Innate Immune Responses Associated with Resistance against Haemonchus contortus in Morada Nova Sheep by João Henrique Barbosa Toscano, Cintia Hiromi Okino, Isabella Barbosa dos Santos, Luciana Aparecida Giraldelo, Marei Borsch von Haehling, Sérgio Novita Esteves, Ana Carolina de Souza Chagas

“…The exacerbated proinflammatory response observed in susceptible animals, at both local and systemic levels, may be a consequence of high H. contortus parasitism. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Conclusions A profile of non-invasive physical health indicators associated with cognitive performance was established, which warrants future incorporation of non-invasive physical health indicators in early risk screening systems for MCI, enabling timely intervention and prevention in older adults. …”
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Effects of Semaglutide Treatment on Psoriatic Lesions in Obese Patients with Type 2 Diabetes Mellitus: An Open-Label, Randomized Clinical Trial by Jelena Petković-Dabić, Ivana Binić, Bojana Carić, Ljiljana Božić, Sanja Umičević-Šipka, Nataša Bednarčuk, Saša Dabić, Mirna Šitum, Snježana Popović-Pejičić, Miloš P. Stojiljković, Ranko Škrbić

“…In conclusion, semaglutide, based on its systemic anti-inflammatory characteristics, could contribute to the treatment of psoriatic obese patients with T2DM.…”
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Medium- to long-term health condition of patients post-COVID-19, exercise intolerance and potential mechanisms: A narrative review and perspective by Fabian Schwendinger, Denis Infanger, Debbie J Maurer, Thomas Radtke, Justin Carrard, Julia M Kröpfl, Aglaia Emmenegger, Henner Hanssen, Christoph Hauser, Udo Schwehr, Hans H Hirsch, Julijana Ivanisevic, Karoline Leuzinger, Aurélien E Martinez, Marc Maurer, Thomas Sigrist, Lukas Streese, Roland von Känel, Timo Hinrichs, Arno Schmidt-Trucksäss

“…Evidence suggests long-term dysfunction in multiple organ systems and exercise intolerance due to various factors, including endothelial damage and, in some patients, subclinical ventricular dysfunction. …”
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Mismatch repair, p53, and L1 cell adhesion molecule status influence the response to chemotherapy in advanced and recurrent endometrial cancer by Jung Chul Kim, Byungsoo Ahn, Yong Jae Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim, Young Tae Kim, Eunhyang Park, Jung-Yun Lee

“…Abstract Objective This study aimed to identify the recurrence and survival rates according to the mismatch repair (MMR), p53, and L1 cell adhesion molecule (L1CAM) status in patients with advanced and recurrent endometrial cancer (EC) receiving systemic chemotherapy. Methods This single-center retrospective cohort study included chemotherapy-naïve patients with advanced-stage (III/IV) or recurrent EC between January 2015 and June 2022 (n = 156), who were administered chemotherapy as adjuvant therapy or first-line palliative treatment. …”
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Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids by Janesh Pillay, Antine W. Flikweert, Matijs van Meurs, Marco J. Grootenboers, Simone van der Sar-van der Brugge, Peter H. J. van der Voort, Morten A. Karsdal, Jannie M. B. Sand, Diana J. Leeming, Janette K. Burgess, Jill Moser

“…Abstract Background Severe and critical COVID-19 is characterized by pulmonary viral infection with SARS-CoV-2 resulting in local and systemic inflammation. Dexamethasone (DEX) has been shown to improve outcomes in critically ill patients; however, its effect on tissue remodeling, particularly collagen turnover, remains unclear. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

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Exploring dual-lidar mean and turbulence measurements over Perdigão's complex terrain by I. L. Coimbra, J. Mann, J. M. L. M. Palma, V. T. P. Batista

“…We suspect that with a stable and less turbulent atmosphere, the scan synchronisation in the dual-lidar systems had a lower impact on the measurement accuracy. …”
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CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

“…Several treatments (eg, chemotherapy, surgery, radiations, hormonal therapy, etc.) are conventionally prescribed for the treatment of BC; however, these are associated with serious systemic aftermaths. In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. …”
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Categorising implementation determinants and strategies within the US HIV implementation literature: a systematic review protocol by Justin D Smith, Brian Mustanski, Virginia McKay, James Lorenz Merle, Dennis Li, Brennan Keiser, Alithia Zamantakis, Artur Queiroz, Carlos G Gallo, Juan A Villamar, Juan Pablo Zapata, Nanette Benbow

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ANTHROPOLOGICAL PROBLEMS IN THE PHILOSOPHICAL WORKS OF RUSSIAN SPIRITUAL ACADEMIES’ TEACHERS OF THE EARLY 20TH CENTURY by M. A. Ershova

“…Scientific novelty. The author systemizes and sums up anthropologic views of the most recognizable ecclesiastical academics in the early 20th century. …”
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Measuring the age-friendliness of cities in the Russian Federation: The translation, validation and application of the age-friendly cities and communities Questionnaire in the city... by Liliya E. Ziganshina, Aizyara F. Garaeva, Liliya I. Talipova, Rustem N. Khairullin, Jeroen Dikken, Joost van Hoof

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Integrating WHO thinking healthy programme for maternal mental health into routine antenatal care in China: a randomized-controlled pilot trial by Anum Nisar, Juan Yin, Jingjun Zhang, Wenli Qi, Jie Yu, Jiaying Li, Xiaomei Li, Atif Rahman

“…Integrating evidence based non-stigmatizing interventions within existing health systems is crucial to reducing psychosocial distress during pregnancy and preventing perinatal depression. …”
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A Comprehensive Review of Direction-of-Arrival Estimation and Localization Approaches in Mixed-Field Sources Scenario by Amir Masoud Molaei, Bijan Zakeri, Seyed Mehdi Hosseini Andargoli, Muhammad Ali Babar Abbasi, Vincent Fusco, Okan Yurduseven

“…By reviewing advances in methodologies and techniques, as well as outlining future research directions aimed at addressing the complexities of mixed-field scenarios, this paper paves the way for the development of more robust and reliable localization systems capable of handling real-world complexities.…”
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Research Progress and Prospects of Key Navigation Technologies for Facility Agricultural Robots by HE Yong, HUANG Zhenyu, YANG Ningyuan, LI Xiyao, WANG Yuwei, FENG Xuping

“…Depending on the type of sensors employed, SLAM technology could be subdivided into vision-based, laser-based and fusion systems. Fusion localization is further categorized into data-level, feature-level, and decision-level based on the types and stages of the fused information. …”
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The baked side: Cow's milk and egg protein threshold dose distributions in children reacting to baked milk and baked egg by Rocco Luigi Valluzzi, MD, Carla Riccardi, MD, Sara Urbani, MD, Davide Ursi, MD, Deborah Zavettieri, MD, Francesco Di Girolamo, PhD, Lamia Dahdah, MD, Veronica Calandrelli, PharmD, Vincenzo Fierro, MD, Alessandro Fiocchi, MD

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Influence of Abutment Screw-Tightening Methods on the Screw Joint: Immediate and Long-Term Stability by Manlin Sun, Yusen Shui, Yuqiang Zhang, Ruiyang Ma, Yuwei Zhao, Hongyu Chen, Ping Yu, Zhi Li, Tingting Wu, Haiyang Yu

“…A total of 150 implants of three different implant systems with different diameters were used in this study. …”
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Enhancing healthcare utilization and reducing preventable hospitalizations: exploring the healthcare-seeking propensity of patients with non-communicable diseases in Rural China by Yanqiu Hou, Wenyu Li, Shangai Li, Linxuan Chen, Jiayu An, Shan Lu

“…Abstract Objective Understanding healthcare-seeking propensity is crucial for optimizing healthcare utilization, especially for patients with chronic conditions like hypertension or diabetes, given their substantial burden on healthcare systems globally. This study aims to evaluate hypertensive or diabetic patients’ healthcare-seeking propensity based on the severity of symptoms, categorizing symptoms as either major or minor. …”
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Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides by Heqian Zhang, Yihan Wang, Yanran Zhu, Pengtao Huang, Qiandi Gao, Xiaojie Li, Zhaoying Chen, Yu Liu, Jiakun Jiang, Yuan Gao, Jiaquan Huang, Zhiwei Qin

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INNOVATIVE METHODS OF TEACHING HISTORY AT MODERN UNIVERSITIES by A. Yu. Suslov, M. V. Salimgareev, Sh. S. Khammatov

“…A modern view on historical education has been proposed as means of students’ systems thinking formation, designing the ideas about the world historical process among students, the mission ofRussia in this process, and evolution ofRussia as a part of the modern civilization. …”
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