Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu... by Maram B Alhawarri, Mohammad G Al-Thiabat, Amit Dubey, Aisha Tufail, Katreen Banisalman, Ghazi A Al Jabal, Eman Alkasasbeh, Esra'a Ibrahim Al-Trad, Bilal Harieth Alrimawi

“…The radius of gyration (Rg) results indicated a consistent value of ~15.3 Å across systems, confirming the role of SG-A in maintaining protein integrity. …”
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Characterizing microcycles’ workload when combining two days structure within single training sessions during congested fixtures in an elite male soccer team by Antonio Gómez-Díaz, Fábio Yuzo Nakamura, Pedro Menezes, João Barreira, Pedro Figueiredo, Diogo Coutinho

“…External load was collected with global positioning systems, while internal load with the rating of perceived exertion (RPE). …”
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Reestablishment of Redox Homeostasis in the Nociceptive Primary Afferent as a Mechanism of Antinociception Promoted by Mesenchymal Stem/Stromal Cells in Oxaliplatin-Induced Chronic... by Anna Lethicia L. Oliveira, Gisele G. L. Santos, Renan F. Espirito-Santo, Gessica Sabrina A. Silva, Afrânio F. Evangelista, Daniela N. Silva, Milena B. P. Soares, Cristiane Flora Villarreal

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Data-driven machine learning approaches for simultaneous prediction of peak particle velocity and frequency induced by rock blasting in mining by Yewuhalashet Fissha, Prashanth Ragam, Hajime Ikeda, N. Kushal Kumar, Tsuyoshi Adachi, P.S. Paul, Youhei Kawamura

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Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital by Ieva Renata Jonaitytė, Vita Karpavičiūtė, Gediminas Kiudelis, Juozas Kupčinskas, Laimas Jonaitis

“…Data on the prevalence of mu-cocutaneous manifestations in IBD patients are very limited, therefore, the aim of this study was to assess the prevalence of skin and mucosal lesions and to determine the relationship with demographic factors, clinical features, and systemic treatment. Materials and methods: Prospective study included 162 out-patients with IBD who were managed in the tertiary care center. …”
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The Efficacy of Conversational AI in Rectifying the Theory-of-Mind and Autonomy Biases: Comparative Analysis by Marcin Rządeczka, Anna Sterna, Julia Stolińska, Paulina Kaczyńska, Marcin Moskalewicz

“…Addressing cognitive biases in AI-human interactions requires systems that can both rectify and analyze biases as integral to human cognition, promoting precision and simulating empathy. …”
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Long-Term Evaluation of Capsulotomy Shape and Posterior Capsule Opacification after Low-Energy Bimanual Femtosecond Laser-Assisted Cataract Surgery by Tommaso Verdina, Chiara Peppoloni, Lucrezia Barbieri, Maria Rosaria Carbotti, Bruno Battaglia, Rodolfo Mastropasqua, Gian Maria Cavallini

“…Methods. 74 eyes operated by a well-trained surgeon with bimanual FLACS technique using low-energy LDV Z8 (Ziemer Ophthalmic Systems AG, Port, Switzerland) were included in the study. …”
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Comprehensive Analysis of VOCs in an Industrial Harbor City: Spatiotemporal Distribution, Health Risk, and Potential Sources by Thi-Hieu Le, Chung-Shin Yuan, Chitsan Lin, Zhi-Ping Hsu, I-Hsin Hsu, Lin-Chi Wang

“…Air VOCs samples were collected continuously in 24 h by canister and analyzed by GC/MS with pre-concentration systems according to U.S. EPA Method TO-15. The source apportionment was defined by diagnostic ratio analysis and positive matrix factorization (PMF) model while ozone formation potentials (OFP) were estimated by maximum incremental reactivity method. …”
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Connective tissue disease-associated interstitial lung disease – A multicenter observational study from India by Sham Santhanam, Pravin Patil, Mohit Goyal, C B Mithun, Parthajit Das, Kavitha Mohanasundaram, Neeraj Jain, Vijaya Prasanna, Keerthi Talari, Himanshu Pathak, Parshant Aggarwal, Deepika Ponnuru, Vikram Raj Jain, Sharath Kumar

“…Rheumatoid arthritis (RA) was the most common CTD associated with ILD followed by systemic sclerosis and mixed connective tissue disorder. …”
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Short-Term Motor Outcomes in Parkinson’s Disease after Subthalamic Nucleus Deep Brain Stimulation Combined with Post-Operative Rehabilitation: A Pre-Post Comparison Study by Kazunori Sato, Yoshihide Hokari, Eriko Kitahara, Nana Izawa, Kozo Hatori, Kaoru Honaga, Genko Oyama, Taku Hatano, Hirokazu Iwamuro, Atsushi Umemura, Yasushi Shimo, Nobutaka Hattori, Toshiyuki Fujiwara

“…The Mini-Balance Evaluation Systems Test (Mini-BESTest), Timed Up and Go test (TUG) seconds and steps, Trunk Impairment Scale (TIS), seconds for 10 times toe-tapping, lower limb extension torque using StrengthErgo240, and center of pressure sway in the quiet standing posture were evaluated preoperatively, postoperatively, and at discharge. …”
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Barriers and facilitators to global access to life-saving skills training: an international cross-sectional survey by Marcus Eng Hock Ong, Freddy Lippert, Lin Zhang, Willem Stassen, So Yeon Joyce Kong, Audrey L Blewer, Yeh Lai Chern, Andrew Fu Wah Ho

“…Where emergency care systems are nascent or absent, bystanders represent the only prehospital emergency care that victims might receive. …”
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A methodical approach for evaluating the variability of productivity and fruit quality in the genetic collections of strawberry (Fragaria × ananassa Duch.) by V. I. Lapshin, V. V. Yakovenko, S. N. Shcheglov, V. N. Podorojny

“…A complicated genomic composition, the  diversity of genetic control systems, and a strong modifying effect of growing conditions on the implementation of quantitative traits make it necessary to improve  methods for analysis of the  genotypic variability of economically  valuable  traits with the  aim of identifying genotypes that  are characterized by stability and adaptive qualities in a wide ecological  range  of growing  conditions. …”
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Enabling regulatory policy globally will promote realization of the potential of animal biotechnology by Eric Hallerman, Justin Bredlau, Luiz Sergio A. Camargo, Maria Lucia Zaidan Dagli, Margaret Karembu, Daniel Kovich, Anne Ndanu Muia, Mariana L. Murrone, Pedro Jesus Rocha-Salavarrieta, Rhodora Romero-Aldemita, Mark Tizard, Mark Walton, Diane Wray-Cahen

“…Abstract Animal biotechnologies have the potential to improve the sustainability and security of our global food systems. Government regulatory authorities are responsible for ensuring the safety of food their citizens consume, whether it is produced via conventional breeding methods or biotechnologies. …”
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Assessment of Treatment Outcomes and Associated Factors Among Pediatric Patients With Burkitt Lymphoma at Kenyatta National Hospital by Divya Kumari Toor, Amsalu Degu, Peter N. Karimi

“…ABSTRACT Background In developing countries, the treatment outcomes of Burkitt lymphoma are poor due to the poorly equipped healthcare systems. In addition, there is limited comprehensive data within the African continent, including Kenya, about the outcomes of treatment for this cancer. …”
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Multisensor Data Fusion and GIS-DRASTIC Integration for Groundwater Vulnerability Assessment With Rainfall Consideration by Wu Jiazhe, Dai Xinrui, Su Yancheng, Zheng Xiangtian, Bushra Ghaffar, Rabiya Nasir, Ahsan Jamil, Zeeshan Zafar, Mohammad Suhail Meer, M. Abdullah-Al-Wadud, Rahila Naseer, Hesham El-Askary

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Cost-effectiveness analysis for implementation of smoking cessation strategies at primary health care settings in Tamil Nadu. by Vasantha Mahalingam, Ramesh Kumar Santhanakrishnan, Muniyandi Malaisamy, Karthick Chelvanayagam, Kavi Mathiyazhagan, Adhin Bhaskar, Karikalan Nagarajan, Jerard Maria Selvam, Surendran Veeraiah, Kavitha Rajsekar, Kirti Tyagi, Ponnuraja Chinnaiyan

“…It is a leading cause of preventable diseases and deaths, with a significant economic burden on healthcare systems and society as a whole. Recognizing the need to address this issue, the implementation of smoking cessation strategies at primary health care (PHC) settings has gained attention. …”
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Long-Term Effects of COVID-19 on Optic Disc and Retinal Microvasculature Assessed by Optical Coherence Tomography Angiography by Mine Ozturk, Deniz Kumova Guler, Ekin Ece Oskan, Feyza Onder

“…We emphasize the need for long-term ophthalmologic and systemic follow-up of COVID-19 patients regarding potential complications.…”
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Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis by Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé

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Hotspots in peril: Misalignment of conservation efforts and ecological values in a shallow coastal sea by Kasper J. Meijer, Oscar Franken, Sterre Witte, Sander J. Holthuijsen, Tjisse van der Heide, Laura L. Govers, Han Olff

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Characterization and in vitro anticancer study of PEGylated liposome dually loaded with ferulic acid and doxorubicin by Andang Miatmoko, Patricia Kinanti Christy, Alfionita Isnaini, Berlian Sarasitha Hariawan, Devy Maulidya Cahyani, Margaret Ahmad, Nuzul Wahyuning Diyah, Mohamad Faris Adrianto, Ravi Kiran Deevi, Iwan Sahrial Hamid, Juni Ekowati

“…Moreover, changes to the DSC thermogram were observed following the incorporation of ferulic acid into the liposome, while the Lipo DOX-FA exhibited a relatively rapid drug release compared to Lipo DOX suggesting a slightly shorter period necessary to attain both therapeutic efficacy and the maintenance of a stable drug encapsulation in the systemic circulation. An in vitro study of LLC and HeLa cells showed that the IC50 values of Lipo DOX-FA were 0.70 µg/mL and 1.56 µg/mL, while the CC50 value in normal HEK cells was 6.50 µg/mL. …”
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