Nomogram-derived immune-inflammation-nutrition score could act as a novel prognostic indicator for patients with head and neck squamous cell carcinoma by Wen-Yan Wang, Yue Chen, Qian Chen, Hong-Wei Sun, Nuo-Xuan Niu, Hong-Hui Li, Yu-Dan Cao, Yan-Xia Bai, Xiang Li, Xiang Li

“…The prognostic accuracy of the SIIN score was assessed by exploiting receiver operating characteristic (ROC) analysis, Kaplan-Meier survival analysis, Cox proportional hazard regression models, calibration and DCA curves.ResultsThe SIIN score was formulated based on six biomarkers-platelet-lymphocyte ratio (PLR), prognostic nutritional index (PNI), systemic immune-inflammation index (SII), albumin-bilirubin index (ALBI), fibrinogen (FIB) and monocyte count-identified by LASSO regression analysis. (1)The SIIN score demonstrated superior predictive value, achieving area under the ROC curve (AUC) values of 0.736 and 0.700 for 3- and 5-year OS. …”
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Climate change and the sustainable use of medicinal plants: a call for “new” research strategies by Olha Mykhailenko, Olha Mykhailenko, Banaz Jalil, Lyndy J. McGaw, Javier Echeverría, Marce Takubessi, Marce Takubessi, Michael Heinrich, Michael Heinrich

“…Despite these growing challenges, there is limited knowledge of potential strategies to prevent or mitigate these impacts, particularly for vulnerable species collected from the wild or harvested from traditional production systems. Hence, effective strategies for preserving and increasing plant populations are urgently needed. …”
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Impact of commercial gut health interventions on caecal metagenome and broiler performance by Gladys Maria Pangga, Banaz Star-Shirko, Androniki Psifidi, Dong Xia, Nicolae Corcionivoschi, Carmel Kelly, Callie Hughes, Ursula Lavery, Anne Richmond, Umer Zeeshan Ijaz, Ozan Gundogdu

“…GHI supplementation generally affected the abundance of microbial enzymes relating to carbohydrate and protein digestion and metabolic pathways relating to energy, nucleotide synthesis, short-chain fatty acid synthesis, and drug-transport systems. These shifts are hypothesised to differentiate performance among groups and cycles, highlighting the beneficial role of several bacteria, including Rikenella microfusus and UBA7160 species. …”
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Expert evaluation of large language models for clinical dialogue summarization by David Fraile Navarro, Enrico Coiera, Thomas W. Hambly, Zoe Triplett, Nahyan Asif, Anindya Susanto, Anamika Chowdhury, Amaya Azcoaga Lorenzo, Mark Dras, Shlomo Berkovsky

“…Similar results were obtained when the systems were evaluated by clinicians, with ChatGPT scoring the highest in four domains (coherency 0.573, consistency 0.908, fluency 0.96 and overall clinical use 0.862). …”
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Case Report: Robot-assisted laparoscopic bladder diverticulectomy: a case series and initial experience by Guangju Ge, Haihong Wang, Qiming Zheng, Shuai Zhang, Huan Wang, Liang Ma

“…To minimize the risk of intraoperative tumor spread, we implemented enhanced surgical techniques. Systemic chemotherapy and adjuvant intravesical chemotherapy were recommended to reduce the risk of tumor recurrence and metastasis.ResultsPostoperative pathology confirmed papillary urothelial carcinoma in all three cases. …”
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Assessment of Knowledge and Practices of Standard Precaution against Blood Borne Pathogens among Doctors and Nurses at Adult Emergency Room in Addis Ababa, Ethiopia by Yohanis Asmr, Lemlem Beza, Hywot Engida, Tariku Bekelcho, Netsanet Tsegaye, Yibeltal Aschale

“…In addition sustainable supply systems should be available in each hospital management.…”
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Effect of High-Pressure Homogenization on the Functional and Emulsifying Properties of Proteins Recovered from <i>Auxenochlorella pyrenoidosa</i> by Alexandros Katsimichas, Maria Katsouli, Nikolaos Spantidos, Maria C. Giannakourou, Petros Taoukis

“…Due to APPC’s great emulsifying properties, <i>A. pyrenoidosa</i> proteins have a promising potential for various applications such as delivery systems stabilization. Additionally, the low energy requirements, continuous processing capability, and scalability of HPH make it a suitable process for industrial applications.…”
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Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey by Sidous, Mellina, Cubaynes, Sarah, Gimenez, Olivier, Drouet-Hoguet, Nolwenn, Dray, Stéphane, Bollache, Loïc, Madhlamoto, Daphine, Ngwenya, Nobesuthu Adelaide, Fritz, Hervé, Valeix, Marion

“…We discuss why signals of prey and predator population dynamics decoupling are less likely to be observed in systems with a high diversity of prey, such as African savannas, and why inputs of mega-carcasses as pulsed resources hardly impacted top-down relationships in the long run. …”
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Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury by Jinlong Zhang, Jinlong Zhang, Longju Qi, Yuyu Sun, Yuyu Sun, Shiyuan Chen, Jinyi Liu, Jiaxi Chen, Fangsu Yan, Wenqi Wang, Qinghua Wang, Liang Chen

“…To address this, we conducted bioinformatics and systems biology analyses to identify molecular biomarkers and pathways that link SCI to chronic pain. …”
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Body composition as an indicator of metabolic changes in mice obtained by <i>in vitro</i> fertilization by M. V. Anisimova, Yanli Gon, G. V. Kontsevaya, A. V. Romashchenko, N. V. Khotskin, A. K. Stanova, L. A. Gerlinskaya, M. P. Moshkin

“…To identify body systems subject to epigenetic transformation during in vitro fertilization (IVF), comparative morphological and functional studies were performed on sexually mature offspring of outbred CD1 mice, specific-pathogen-free (SPF), obtained by IVF (experiment) and natural conception (control). …”
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Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments by Amit Verma, Vikas Pandey, Catherine Sherry, Taylor Humphrey, Christopher James, Kailie Matteson, Jason T. Smith, Alena Rudkouskaya, Xavier Intes, Margarida Barroso

“…The study demonstrates that FLI is a powerful analytical tool to monitor the delivery of antibodydrugs both in cell cultures and in vivo live systems. Especially, MFLI FRET is a unique imaging modality that can directly quantify target engagement with the potential to elucidate the role of the TME in drug delivery efficacy in intact live tumor xenografts.…”
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Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study by Erin P. Ferranti, Jennifer K. Frediani, Rebecca Mitchell, Jolyn Fernandes, Shuzhao Li, Dean P. Jones, Elizabeth Corwin, Anne L. Dunlop

“…These findings support that there are systemic metabolic disruptions that are detectable in early pregnancy (8-14 weeks of gestation) among pregnant African American women who develop PE and gHTN. …”
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Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review by Irfan Anjum, Ayesha Nasir, Faiza Naseer, Faiza Naseer, Ahsan Ibrahim, Bisma Rehman, Fawad Bashir, Qura Tul Ain

“…The coupling of phytotherapy with novel drug delivery systems such as nanoparticles, liposomes, nanotubes, quantum dots, etc. can help translate these beneficial effects of phytochemicals into clinical practice. …”
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The impact of food-based incentive behaviors on oral health among Saudi children: a cross-sectional study by Yasir Dilshad Siddiqui, Saud Hamdan Almaeen, Ahmed Shawkat Hashem, Ahmed Ali Ahmed Almuntashiri, Mohammed Nadeem Baig, Abdullah Hammad Alshammari, Rital Jamal Alwaqid, Haifa Ali Almutairi, Raha Ahmed, Rakhi Issrani, Farooq Ahmad Chaudhary

“…These findings highlight the need for targeted educational and intervention strategies that address cultural practices and promote healthier reward systems. By reducing sugary food rewards and encouraging non-food-based incentives, improvements in children’s oral health can be achieved.…”
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Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite by Alta E. G. Howells, Alta E. G. Howells, Lilja M. Quinn, Lilja M. Quinn, Miguel G. Silva, Miguel G. Silva, Kylie Akiyama, Kylie Akiyama, Lucas M. Fifer, Lucas M. Fifer, Grayson Boyer, Srishti Kashyap, Kirt Robinson, Kirt Robinson, Jared Broddrick, Everett L. Shock, Tori M. Hoehler

“…These results demonstrate the applicability of an energy availability framework for interpreting methanogen ecology in serpentinizing systems.…”
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A Seventeen Multilevel High-Power Application Inverter with Low Total Harmonic Distortion by Ajmal Farooq, Shanshan Tu, Fiaz Ahmad, Muhammad Zeeshan Malik, Obaid U. Rehman, Ghulam Hafeez, Sadaqat ur Rehman

“…In this paper, a new topology of multilevel inverter (MLI) is designed with a fewer number of components and low total harmonic distortion (THD) for high-power photovoltaic (PV) systems. The key limitations of conventional MLI topologies are high total harmonic distortion (THD) and the use of a large number of switching components due to which the cost of the overall inverter is high. …”
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A complete structural analysis of the FⅠ17 strike-slip fault and its hydrocarbon enrichment factors, Tarim basin, NW China by Shi Chen, Shi Chen, Xinxin Liang, Xinxin Liang, Xingguo Song, Xingguo Song, Yintao Zhang, Zhou Xie, Yuan Neng, Yuan Neng, Pengfei Kang, Jianxun Zhou, Jianxun Zhou

“…Analyzing the FⅠ17 fault offers crucial insights into the role of basement structures on the evolution and formation of intracratonic strike-slip fault systems. This study utilizes the latest seismic data and integrating the foundation of previous research to conduct a detailed investigation into the spatial distribution, deformation intensity, activity phases, and formation mechanisms of the fault. …”
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Combatting Salmonella: a focus on antimicrobial resistance and the need for effective vaccination by Junaid Nazir, Tasaduq Manzoor, Afnan Saleem, Ubaid Gani, Sahar Saleem Bhat, Shabir Khan, Zulfqarul Haq, Priyanka Jha, Syed Mudasir Ahmad

“…Strengthening surveillance systems and promoting collaborative global efforts are essential to effectively control and reduce the burden of Salmonella.…”
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Integrating microplastic research in sustainable agriculture: Challenges and future directions for food production by Marcelo Illanes, María-Trinidad Toro, Mauricio Schoebitz, Nelson Zapata, Diego A. Moreno, María Dolores López-Belchí

“…Microplastics (MPs) have been identified as modifiers of plant physiology; therefore, these particles present a risk to the quality and safety of plant food production systems. One relevant question is how these emerging pollutants interact with the increasingly extreme environmental conditions of today. …”
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The clean analysis process of Mn2+ for industries: a comparative study on direct determination of high-concentration Mn2+ in solution using spectrophotometry by Yanli Xu, Fuyuan Xu, Yong Liu, Guangbin Zhu, Ying Chen, Ning Duan

“…The EC method’s minimal time consumption and cost-effectiveness make it suitable for automation and integration into industrial systems for continuous, real-time monitoring. This research offers valuable insights into high-concentration Mn2+ determination using spectrophotometry, highlighting the EC method’s potential for real-time monitoring and its adaptability for large-scale industrial operations. …”
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