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70841
A Nationwide Exploration of Social Inequalities in Cancer Mortality Amidst the COVID‐19 Pandemic in Belgium
Published 2025-01-01“…ABSTRACT Background The COVID‐19 pandemic disrupted global health systems, impacting cancer care and potentially increasing cancer mortality, especially among socioeconomically disadvantaged individuals. …”
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70842
Lyme disease associated neurological and musculoskeletal symptoms: A systematic review and meta-analysis
Published 2025-02-01“…Background and objective: Lyme disease, caused by Borrelia burgdorferi, presents major health challenges worldwide, leading to serious neurological and musculoskeletal issues that impact patients' lives and healthcare systems. This systematic review and meta-analysis aim to determine the prevalence and link between Lyme disease and these complications, aiming to enhance clinical and public health approaches. …”
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70843
X-ray pulsed light curves of highly compact neutron stars as probes of scalar–tensor theories of gravity
Published 2024-12-01“…Our investigation is motivated by the increased sensitivity of the pulse to the scalar charge of the spacetime in such high compactness regimes, making these systems exceptionally suitable for scrutinizing deviations from GR, notably phenomena such as spontaneous scalarization, as predicted by STT. …”
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70844
Mutant Fam20c knock-in mice recapitulate both lethal and non-lethal human Raine Syndrome
Published 2025-01-01“…Conclusion This finding also implicated that the osteosclerotic features resulting from Fam20c deficiency could be a semblance on the basis of rickets, which is most likely triggered by the alterations in the systems other than skeleton.…”
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70845
Salvage pathway of vitamin B12 absorption in chickens with mutant tumor virus a receptor
Published 2025-02-01“…Naturally occurring genetic variants in the TVA gene determine susceptibility or resistance to ALV-A and -K, but the effects of these mutated TVA on vitamin B12 uptake have not been investigated systemically. We found four TVA variants comprising the wild type (TVAWT), a single nucleotide polymorphism variant (TVASNP), and two partial deletions in the splicing branch point region (TVAR). …”
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70846
Short-Circuit Performance Analysis of Commercial 1.7 kV SiC MOSFETs Under Varying Electrical Stress
Published 2025-01-01“…By surpassing the shortcomings of lower voltage classes, 1.7 kV SiC MOSFETs can be a more reliable, and efficient choice for operating at higher voltages in next-generation power systems.…”
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70847
Unveiling molecular insights: in silico exploration of TLR4 antagonist for management of dry eye syndrome
Published 2024-05-01“…Celastrol, lumacaftor and nilotinib were selected for further molecular dynamics studies for a deeper understanding of molecular systems consisting of protein and ligands by using the Desmond module of the Schrodinger Suite.Results The docking results revealed that the compounds are having binding affinity in the range of −5.1 to −8.78 based on the binding affinity and three-dimensional interactions celastrol, lumacaftor and nilotinib were further studied for their activity by molecular dynamics. …”
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70848
Case Report: Novel ADA2 variants cause atypical adenosine deaminase 2 deficiency
Published 2025-01-01“…The patient exhibited significant systemic inflammation and multiple vasculitis. Whole-exome sequencing showed c.1358A>G p. …”
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70849
Construction and Release Characteristics of 3D Printed Spaced Multi-layer Structure of Lutein Emulsion Gel
Published 2025-02-01“…The preparation parameters of lutein-loaded and unloaded emulsion gels were screened by evaluating the rheological properties and 3D printing characteristics. 3D printed gel systems with different intervals of multilayers structures were constructed to explore the effects of the number of spacer layers and the positioning of empty layers in spaced multi-layer structures on the release characteristics and bioaccessibility of lutein. …”
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70850
Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms
Published 2025-01-01“…Studying these mechanisms necessitates computational systems biology methods. This work aims to reconstruct and analyze the gene network associated with miRNA regulation of wheat adaptation to drought. …”
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70851
Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department
Published 2025-01-01“… Introduction: Stroke is a leading cause of morbidity and long-term disability worldwide, significantly impacting health systems and personal lives. Disparities in European access to stroke care suggest an increased burden on individuals and society. …”
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70852
Comparative genomics analyses of Actinobacteriota identify Golgi phosphoprotein 3 (GPP34) as a widespread ancient protein family associated with sponge symbiosis
Published 2025-01-01“…Results Our analysis uncovered several differences between symbiotic and free-living bacteria, including an increased abundance of genes encoding prokaryotic defense systems (PDSs) and eukaryotic-like proteins (ELPs) in symbionts. …”
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70853
Mineralogy and geochemistry of shale from Shanxi Formation, Southern North China Basin: Implication for organic matter accumulation
Published 2025-04-01“…This suggests that the intensity of OM modification prior to diagenesis plays a pivotal role in OM accumulation, aligning with the positive correlation between inertinite proportion and TOC content. (3) Organic matter inputs from fluvial systems were likely influenced by upstream mire conditions, where precursor peat may have accumulated. …”
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70854
Combination of ataxia telangiectasia and Rad3-related inhibition with ablative radiotherapy remodels the tumor microenvironment and enhances immunotherapy response in lung cancer
Published 2024-11-01“…These findings underscore the importance of combination therapies for enhancing systemic antitumor immune responses and outcomes.…”
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70855
Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation
Published 2025-01-01“…The administration of the ectodomain of HLA-G2, designated the soluble HLA-G2 homodimer, showed significant immunosuppressive effects in mouse models of rheumatoid arthritis and systemic lupus erythematosus, presumably by binding to a mouse ortholog of LILRB2, paired immunoglobulin-like receptor B. …”
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70856
Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections
Published 2021“…BV activation of the cellular and humoral immune systems should be explored for the application of complementary medicine for the management of SARS-CoV-2 infections. …”
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70857
Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
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70858
THE GYPSY MINORITY IN ROMANIA: A STUDY IN MARGINALITY
Published 2009-07-01“…Les études sociales présentent souvent les tsiganes comme un groupe défavorisé avec un niveau de vie relativement faible et accès réduit au système de santé. Les tsiganes en Roumanie n’en représentent pas une exception et cet étude examine la situation du groupe minoritaire, se référant particulièrement à la période de transition caractérisée par des majeures innovations politiques et améliorations matérielles, surtout à cause d’un gros revenu européen. …”
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70859
Semantic Segmentation Method for High-Resolution Tomato Seedling Point Clouds Based on Sparse Convolution
Published 2024-12-01“…Semantic segmentation of three-dimensional (3D) plant point clouds at the stem-leaf level is foundational and indispensable for high-throughput tomato phenotyping systems. However, existing semantic segmentation methods often suffer from issues such as low precision and slow inference speed. …”
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70860
A novel 3D analytical model and numerical study of bimorph piezoelectric actuators in d33 mode
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