Harnessing the Influence of Pressure and Nutrients on Biological CO₂ Methanation Using Response Surface Methodology and Artificial Neural Network—Genetic Algorithm Appro... by Alexandros Chatzis, Konstantinos N. Kontogiannopoulos, Nikolaos Dimitrakakis, Anastasios Zouboulis, Panagiotis G. Kougias

“…The results highlight the synergistic effects of pressure and trace metals in enhancing gas–liquid mass transfer and enzymatic pathways, demonstrating the potential of computational modeling and experimental validation to optimize biological methanation systems, contributing to sustainable methane production.…”
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The Influence of Osteoporosis and Diabetes on Dental Implant Stability: A Pilot Study by Liliana Sachelarie, Ioana Scrobota, Felicia Cioara, Timea Claudia Ghitea, Corina Laura Stefanescu, Liana Todor, Georgiana Ioana Potra Cicalau

“…<i>Background and Objectives</i>: Dental implants are a reliable solution for tooth loss; however, systemic conditions like osteoporosis and diabetes, which affect bone quality, healing, and stability, underline the importance of understanding their impact on enhanced outcomes. …”
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Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival by Monika Komza, Jesminara Khatun, Jesse D. Gelles, Andrew P. Trotta, Ioana Abraham-Enachescu, Juan Henao, Ahmed Elsaadi, Andriana G. Kotini, Cara Clementelli, JoAnn Arandela, Sebastian El Ghaity-Beckley, Agneesh Barua, Yiyang Chen, Mirela Berisa, Bridget K. Marcellino, Eirini P. Papapetrou, Masha V. Poyurovsky, Jerry Edward Chipuk

“…Here, we investigated a potent small molecule inhibitor to Class I glucose transporters, KL-11743, using glycolytic leukemia cell lines and patient-based model systems. Our results reveal that while several metabolic adaptations occur in response to acute glucose uptake inhibition, the most critical is increased mitochondrial oxidative phosphorylation. …”
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Protocol to assess bottlenecks inhibiting the scaling up of evidence-based family planning practices in low-income and middle-income countries using mixed methods by James Kiarie, Moazzam Ali, Rita Kabra, Komal Preet Allagh, Kathryn Church, Abdulmumin Saad, Petrus Steyn

“…To gain a better understanding of the factors that may be hindering the sustained scale-up of these interventions, WHO has developed an assessment protocol to systematically identify the health systems’ ‘bottlenecks’ to implementation and to then identify solutions and develop strategies to address them.Methods and analysis A mixed method approach that includes document review, secondary data analysis (from surveys, service delivery data and case studies) and key informant interviews with policymakers, programme managers, health providers and community groups will be used to identify bottlenecks. …”
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Study on the insulation performance of C5F10O gas mixture in cold climates by Runlong Zhang, Xiaohui Zhang, Zhilei Xu, Keliang Dong, Jinfeng Zheng, Shicheng Feng, Zhaolin Zhou, Hui Zhu

“…Gas-insulated switchgear (GIS) is essential for the safe, stable, and efficient operation of high-voltage power systems. Insulating gas plays a critical role in achieving electrical insulation and stable operation in GIS equipment. …”
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Patient selection criteria for transcatheter implantation of aortic valve by M.B. Todurov, O.V. Zelenchuk, A.V. Khokhlov, M.V. Stan, N.O. Yashchenko

“…As the experience of interventional cardiologists increases and new valve designs and delivery systems are developed, better clinical outcomes and lower complication rates can be expected, which will contribute to the expansion of indications for TAVI. …”
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Persistent Retinal Detachment in Retinoblastoma: The Challenges by Sophia El Hamichi, Dhariana Acon, Veronica Kon Graversen, Aaron S. Gold, Audina M. Berrocal, Timothy G. Murray

“…Eight eyes had local treatment with transpupillary laser, 6 eyes received IAC, and 3 patients received systemic chemotherapy. In 9 eyes, the RD had both exudative and tractional components. …”
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Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke by Payam Saadat, Alijan Ahmadi Ahangar, Mansor Babaei, Mandana Kalantar, Mohammad Ali Bayani, Hiva Barzegar, Hemmat Gholinia, Farbod Zahedi Tajrishi, Sekineh Faraji, Fatemeh Frajzadeh

“…A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. …”
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Ecological imbalance on the area of Shapahar Upazila, Naogaon district over three decades (1993÷2023) and prediction trend next ten years: a GIS approach by Nazmul Hossain, Ahammodullah Hasan, Jannatul Adnan, Tasmia Jahin Mim, Arman Hossain, Ariful Molla, Noor Hossain, Habib Ibne Jahan, Abdulla Al Mamun

“…This study analyzes land cover changes over three decades (1993-2023) in Shapahar Upazila using Geographic Information Systems (GIS) and remote sensing techniques. The analysis reveals significant shifts in vegetation, water bodies, bare soil, and settlement areas, correlating these changes with shifts in temperature and precipitation. …”
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Evolution of Functional and Paraclinical Markers as Predictive Factors in Pediatric Late-Onset SMA Under Nusinersen Treatment: The Role of CSF pNF-H by Mihaela Badina, Gabriel Cristian Bejan, Corina Sporea, Andrada Mirea

“…Spinal Muscular Atrophy (SMA) is a rare neurodegenerative disease caused by insufficient synthesis of SMN protein, characterized by progressive muscle weakness, atrophy, and complications affecting the respiratory and digestive systems. Disease severity tends to be greater when symptoms manifest at an earlier age. …”
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Robustness and limitations of maximum entropy in plant community assembly by Jelyn Gerkema, Daniel E. Bunker, Andrew M. Cunliffe, Erika Bazzato, Michela Marignani, Tommaso Sitzia, Isabelle Aubin, Stefano Chelli, Julieta A. Rosell, Peter Poschlod, Josep Penuelas, Arildo S. Dias, Christian Rossi, Tanvir A. Shovon, Juan A. Campos, Mark C. Vanderwel, Sharif A. Mukul, Bruno E.L. Cerabolini, Thomas Sibret, Bruno Hérault, Sylvain Schmitt, Pedro Higuchi, James L. Tsakalos, Decky I. Junaedi, Yun-Peng Zhao, Vanessa Minden, Ana Carolina da Silva, Tereza Mašková, Roberto Canullo, Ning Dong, Edwin T. Pos

“…We further hypothesise this could signal that stochastic processes are more dominant within species-rich systems, for example, due to functional redundancy or the existence of multiple fitness strategies. …”
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Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice by Shailendra P. Singh, Lars Bellner, Luca Vanella, Jian Cao, John R. Falck, Attallah Kappas, Nader G. Abraham

“…Obesity and metabolic syndrome and associated adiposity are a systemic condition characterized by increased mitochondrial dysfunction, inflammation, and inhibition of antioxidant genes, HO-1, and EETs levels. …”
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Harnessing the power of proteins in modulation of miRNAs for targeting Iron deficiency Anemia: Opinion for future implications and strategies by Ray Wagiu Basrowi, Ray Wagiu Basrowi, Ray Wagiu Basrowi, Tonny Sundjaya, Tonny Sundjaya, Dessy Pratiwi, Nurlinah Amalia, Nurlinah Amalia, Nurlinah Amalia, Yosi Yohanes Putra Tandi, Muhammad Yasir Syafa’atulloh, Garuda Nusantara Putra Utomo, Muhammad Abdir Rahman Albarok, Fahrul Nurkolis

“…Emerging evidence underscores the pivotal role of miRNAs—such as miR-15a, miR-24, miR-150, and miR-223—in regulating erythropoiesis, with dysregulation linked to hematologic and systemic diseases. Proteins, acting as modulators of miRNA activity, present innovative pathways for intervention by influencing erythropoiesis at multiple stages, from stem cell proliferation to red blood cell maturation. …”
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Atomized Neutrophil Membrane-coated MOF Nanoparticles for Direct Delivery of Dexamethasone for Severe Pneumonia by Yixiao Yang, Lizhen Yan, Han Zhang, Chuanguang Xiao, Kai Wang

“…Background: Dexamethasone has proven life-saving in severe acute respiratory syndrome (SARS) and COVID-19 cases. However, its systemic administration is accompanied by serious side effects. …”
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Lower electronic health record adoption and interoperability in rural versus urban physician participants: a cross-sectional analysis from the CMS quality payment program by A. Jerrod Anzalone, Carol R. Geary, Ran Dai, Shinobu Watanabe-Galloway, James C. McClay, James R. Campbell

“…EHR adoption was significantly higher in urban (74%) than in rural areas (64%). Epic Systems dominated the market in both settings. Multivariable logistic regression indicated lower odds of EHR adoption among rural physicians (OR: 0.79, CI: 0.76–0.82). …”
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Spermidine alleviates thymopoiesis defects and aging of the peripheral T-cell population in mice after radiation exposure by Kengo Yoshida, Zhenqiu Liu, Yoshiko Kubo, Masahiko Miura, Mika Yamaoka, Hiroko Nagamura, Munechika Misumi, Yoichiro Kusunoki

“…However, the mechanisms by which these systemic factors interact to cause T cell aging remain unclear. …”
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Honest Computing: achieving demonstrable data lineage and provenance for driving data and process-sensitive policies by Florian Guitton, Axel Oehmichen, Étienne Bossé, Yike Guo

“…It ensures that computer systems and software operate honestly and reliably without hidden agendas, biases, or unethical practices. …”
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Promoting ER stress in a plasmacytoid dendritic cell line drives fibroblast activation by Beatriz H. Ferreira, Inês S. Silva, Andreia Mendes, Fátima Leite-Pinheiro, Adrienne W. Paton, James C. Paton, Iola F. Duarte, Philippe Pierre, Catarina R. Almeida

“…Abstract Background Fibrosis remains a major complication in several chronic diseases, including systemic sclerosis (SSc). Plasmacytoid dendritic cells (pDCs) are innate immune cells that play a key role in the development of fibrosis in SSc patients, through still poorly defined mechanisms. …”
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Enhancing the efficacy of near-infrared photoimmunotherapy through intratumoural delivery of CD44–targeting antibody–photoabsorber conjugatesResearch in context by Yuichi Adachi, Kotaro Miyake, Kika Ohira, Shingo Satoh, Kentaro Masuhiro, Ryuya Edahiro, Yuya Shirai, Maiko Naito, Yujiro Naito, Takayuki Shiroyama, Shohei Koyama, Haruhiko Hirata, Kota Iwahori, Izumi Nagatomo, Yoshito Takeda, Atsushi Kumanogoh

“…The conventional PIT regimen involves the systemic delivery of an antibody–photoabsorber conjugate, followed by a 24-h waiting period to ensure adequate localisation on the target cells. …”
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In-situ/operando study of Cu-based nanocatalysts for CO2 electroreduction using electrochemical liquid cell TEM by Jiawei Wan, Jiawei Wan, Qiubo Zhang, Ershuai Liu, Ershuai Liu, Yi Chen, Yi Chen, Jiana Zheng, Jiana Zheng, Amy Ren, Walter S. Drisdell, Walter S. Drisdell, Haimei Zheng, Haimei Zheng

“…Using Cu and CuAg nanowire catalysts for CO2RR as model systems, we describe the experimental procedures and findings. …”
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