Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β by Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen

“…Neurodegenerative diseases such as Alzheimer’s disease (AD) pose substantial challenges to patients and health-care systems, particularly in countries with aging populations. …”
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Radiomics-based biomarker for PD-1 status and prognosis analysis in patients with HCC by Gulizaina Hapaer, Feng Che, Qing Xu, Qian Li, Ailin Liang, Zhou Wang, Jituome Ziluo, Xin Zhang, Yi Wei, Yuan Yuan, Bin Song, Bin Song

“…PurposeTo investigate the impact of preoperative contrast-enhanced CT-based radiomics model on PD-1 prediction in hepatocellular carcinoma (HCC) patients.MethodsThe study included 105 HCC patients (training cohort: 72; validation cohort: 33) who underwent preoperative contrast-enhanced CT and received systemic sorafenib treatment after surgery. Radiomics score was built for each patient and was integrated with independent clinic radiologic predictors into the radiomics model using multivariable logistic regression analysis.ResultsSeventeen radiomics features were finally selected to construct the radiomics score. …”
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Nitrogen-rich covalent organic polymers for efficient solid phase extraction of nonsteroidal anti-inflammatory drugs from water samples by Yuqi Cheng, Jia Li, Xiaochen Xiu, Xinghua Teng, Wen Zhang, Lei Ji, Leilei Wang

“…Non-steroidal anti-inflammatory drugs (NSAIDs) have received increasing attention owing to their ubiquitous occurrence in environmental water systems and adverse effects. In order to monitor trace levels of NSAIDs from complex water samples, development of facile and efficient sample pretreatment is of great significance. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms by Irina Tiganova, Yulia Zhizhimova, Eteri Tolordava, Elena Makarova, Natalia Shevlyagina, Alexander Barmashov, Maria Baryshnikova, Vladimir Zhukhovitsky, Yulia Romanova

“…Aim: Biofilms of pathogenic bacteria are phenotypically resistant to antibiotics and other antimicrobial agents, host immune systems, and adverse environmental conditions, and are responsible for most chronic infections. …”
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A Multimodal Approach to Analgesia in Anorectal Surgery by T. N. Garmanova, D. R. Markaryan, E. A. Kazachenko, A. M. Lukianov, M. A. Kazachenko, M. A. Agapov

“…Acetaminophen combined with other systemic analgesics is advisable for patients with severe pain. …”
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A Rapid Screening Method for Sibutramine Hydrochloride in Natural Herbal Medicines and Dietary Supplements by Qi Liang, Yue Zhuang, Jun Ma, Jinyan Wang, Rui Feng, Ruisi He, Zhuoya Luo, Honghao Wang, Ruoting Zhan

“…While a variety of chromatography- and electrophoresis-based systems have been reported to measure this analyte, they generally suffer from high costs, complicated sample preparation, and a costly analytical infrastructure. …”
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ConciliaMed: an interactive mobile and web tool to reconcile chronic medications of patients undergoing elective surgery by Bernardo Santos-Ramos, Eva Rocío Alfaro-Lara, María Dolores Santos-Rubio, Pablo Ciudad-Gutiérrez, Paloma Suárez-Casillas, Ana Belén Guisado-Gil

“…The triggering of dose and duplication alerts for users or the integration of ConciliaMed with electronic prescription systems were some of the more requested adaptations by the test participants.Discussion The ability to generate an editable reconciliation report or transfer information between users are some of the features of ConciliaMed that encourage its use. …”
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What drives consumers’ intention towards fairness-oriented products purchasing? An emotion-extended model of theory of planned behaviour by Antonella Samoggia, Giulia Rossi, Andrea Fantini, Evangelia Mouchtaropoulou, Notis Argiriou

“…Fairness-oriented products have attracted increased interest in the last few years, particularly within the context of agrifood systems. However, in scholarly literature, limited studies are available where researchers discuss what drives consumers' choices towards fair food. …”
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Artisanal and farmer bread making practices differently shape fungal species community composition in French sourdoughs by Michel, Elisa, Masson, Estelle, Bubbendorf, Sandrine, Lapicque, Léocadie, Nidelet, Thibault, Segond, Diego, Guézenec, Stéphane, Marlin, Thérèse, Devillers, Hugo, Rué, Olivier, Onno, Bernard, Legrand, Judith, Sicard, Delphine

“…Preserving microbial diversity in food systems is one of the many challenges to be met to achieve food security and quality. …”
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Effect of Proinflammatory Cytokines (IL-6, TNF-α, and IL-1β) on Clinical Manifestations in Indian SLE Patients by Vinod Umare, Vandana Pradhan, Milind Nadkar, Anjali Rajadhyaksha, Manisha Patwardhan, Kanjaksha K. Ghosh, Anita H. Nadkarni

“…Systemic lupus erythematosus (SLE) is an inflammatory rheumatic disease characterized by production of autoantibodies and organ damage. …”
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Effects of Dexmedetomidine Infusion on Inflammatory Responses and Injury of Lung Tidal Volume Changes during One-Lung Ventilation in Thoracoscopic Surgery: A Randomized Controlled... by Chun-Yu Wu, Yi-Fan Lu, Man-Ling Wang, Jin-Shing Chen, Yen-Chun Hsu, Fu-Sui Yang, Ya-Jung Cheng

“…One-lung ventilation in thoracic surgery provokes profound systemic inflammatory responses and injury related to lung tidal volume changes. …”
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Cognitive-Behavioral Therapists’ Experience on Relevance of Sleep and Sleep Disorders in Training and Clinical Practice: A Survey Study from Italy by Chiara Baglioni, Andrea Galbiati, Debora Meneo, Greta Cavadini, Francesca Gelfo, Francesco Mancini, Carlo Buonanno

“…Adding information on different countries is important, as national health systems differ significantly, and distinct evidence-based pathways for change may be proposed. …”
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Impact of Ag Coating Thickness on the Electrochemical Behavior of Super Duplex Stainless Steel SAF2507 for Enhanced Li-Ion Battery Cases by Hyeongho Jo, Jung-Woo Ok, Yoon-Seok Lee, Sanghun Lee, Yonghun Je, Shinho Kim, Seongjun Kim, Jinyong Park, Jonggi Hong, Taekyu Lee, Byung-Hyun Shin, Jang-Hee Yoon, Yangdo Kim

“…This result is expected to aid the development of advanced Li-ion battery systems in the future.…”
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Exploring the influence of pregnancy on cognitive function in women: a systematic review by Jana Younis, Malak Bleibel, Jad El Masri, Ali Ismail, Linda Abou‑Abbas

“…Such initiatives aim to mitigate potential impacts on maternal well-being, advocating for comprehensive support systems tailored to pregnant individuals navigating cognitive shifts during this transformative period.…”
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Validity of E-PASS Score for Evaluating Perioperative Minor Complications Associated with Carotid Endarterectomy by Yutaka MORISHIMA, Masahito KAWABORI, Yoichi ITO, Masayuki GEKKA, Koji FURUKAWA, Yoshimasa NIIYA, Miki FUJIMURA

“…To predict long-term morbidity and mortality, various scoring systems have been considered; nonetheless, a model that can be utilized to estimate nonmajor temporary complications and minor complications is currently lacking. …”
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Assessing the Efficacy of Gelatin Composite 3D Scaffolds in Cardiovascular Tissue Engineering: An In Vitro Study by Mohammad Mahdi Safikhani, Azadeh Asefnejad, Rouhollah Mehdinavaz Aghdam, Sadegh Rahmati

“…This study confirms that 3D-printed SA/HA/Gel scaffolds incorporating heparin exhibit desirable physicochemical and biological attributes, making them suitable for drug release systems in cardiovascular tissue applications.…”
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Enhancing Infection Control in ICUS Through AI: A Literature Review by Aditya Amit Godbole, Paras, Maanya Mehra, Sumitaksha Banerjee, Poulami Roy, Novonil Deb, Sarang Jagtap

“…Real‐time patient monitoring and alert systems powered by AI are shown to enhance infection detection and patient outcomes. …”
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Clinical trial participation, clinical care, and patient outcomes by practice setting: a real-world database analysis of patients with Chronic Lymphocytic Leukemia or Mantle Cell L... by Debora S. Bruno, Manoj Khanal, Xiaohong Li, Maricer P. Escalon, Katherine Winfree, Lisa M. Hess

“…Eligible patients were diagnosed with either CLL or MCL from 2013–2022 who received systemic therapy for their disease. Overall survival (OS) was analyzed using Kaplan Meier method, censoring patients without events at last observation in the database. …”
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Biochemical Properties of the Acid Ectophosphatase Activity of <i>Phytomonas serpens</i> Involved in Cell Proliferation by Luiz Fernando Carvalho-Kelly, Anita Leocadio Freitas-Mesquita, Thaís Souza Silveira Majerowicz, José Roberto Meyer-Fernandes

“…Given that <i>P. serpens</i> can uptake inorganic phosphate (P_i) from the extracellular medium, it is likely that its ectophosphatase activity acts together with the transport systems in the P_i acquisition process. …”
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Uncertainty impact of isotherm models on liquid-phase adsorption thermodynamics: A bayesian inference perspective by Thiago Reschützegger, Nina Paula Gonçalves Salau

“…P(ΔH∘<0)>0.5), which often deviate from established thermodynamic expectations across different systems. Despite achieving good fit statistics (e.g., R² ≈ 0.99), this flexibility in the Sips model does not consistently translate into reliable thermodynamic interpretations. …”
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