Understanding Nigeria’s antibiotic resistance crisis among neonates and its future implications by Victor Oluwatomiwa Ajekiigbe, Ikponmwosa Jude Ogieuhi, Temiloluwa Adebayo Odeniyi, Praise Oluwatobi Ogunleke, Josiah Temitope Olatunde, Adedoyin Veronica Babalola, Akintunde Abisoye Omoleke, Tolulope Felix Omitade, Damilare Emmanuel Olakanmi, Adewunmi Akingbola, Chidera Stanley Anthony

“…Some reasons for the continuous trend include but are not limited to unregulated antibiotic purchase and use, inadequate surveillance systems, and cultural determinants and socioeconomic issues. …”
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Diagnosing and Treating ANCA-Associated Vasculitis within the COVID-19 Era: A Challenging Case Report by Erjola Likaj, Larisa Shehaj, Deniona Nunci, Lordian Nunci, Irda Rrugeja, Merita Rroji, Saimir Seferi, Nertila Gjonaj, Alma Idrizi, Arjana Strakosha

“…Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)- associated vasculitis (AAV) is a rare group of systemic autoimmune diseases that primarily target small blood vessels. …”
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Evaluation of Inflammatory Markers in a Large Sample of Obstructive Sleep Apnea Patients without Comorbidities by Izolde Bouloukaki, Charalampos Mermigkis, Nikolaos Tzanakis, Eleftherios Kallergis, Violeta Moniaki, Eleni Mauroudi, Sophia E. Schiza

“…Systemic inflammation is important in obstructive sleep apnea (OSA) pathophysiology and its comorbidity. …”
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Indigenous university students' perceptions regarding nature, their daily lives and climate change: a photovoice study by Ieda M. A. V. Dias, Antonio Jose Grande, Paulo T. C. Jardim, Alessandra Aparecida Vieira Machado, Jacks Soratto, Maria Inês da Rosa, Luciane Bisognin Ceretta, Leonardo Roever, Xanthi Zourntos, Seeromanie Harding

“…Results The study revealed key themes, including (1) the fragility of ecosystems critical to Indigenous livelihoods, (2) the erosion of traditional knowledge systems due to environmental and social disruptions, and (3) the need for community-driven strategies to protect territories and preserve cultural identities. …”
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Evaluating the implementation and impact of a volunteer navigation oncology support programme: study protocol for a pragmatic, real-world hybrid type 2 study by Charlotte Waugh, Noah Federman, Gabrielle B Rocque, D'Ambra N Dent, Emily K Hill, Ian Bostock Rosenzweig, Bonny Morris, Arif Kamal

“…This pragmatic evaluation of real-world implementation of volunteer navigation in the oncology setting will support future efforts to scale-up this intervention across US health systems.Ethics and dissemination This study was approved by University of Morehouse School of Medicine Social and Behavioral (IRB), which served as the IRB for record for this project (IRB-2025819–2). …”
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Identification of Biomarkers of Arrhythmogenic Cardiomyopathy (ACM) by Plasma Proteomics by Sinda Zarrouk, Houda Ben-Miled, Nadia Rahali, Josef Finsterer, Fatma Ouarda

“…High-throughput plasma proteomic profiling, a powerful tool for gaining insights into disease pathophysiology at the systems biology level, has not been used to study ACM. …”
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Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer by Jeremy L. Pinyon, Georg vonJonquieres, Stephen L. Mow, Amr Al Abed, Keng‐Yin Lai, Mathumathi Manoharan, Edward N. Crawford, Stanley H. Xue, Sarah Smith‐Moore, Lisa J. Caproni, Sarah Milsom, Matthias Klugmann, Nigel H. Lovell, Gary D. Housley

“…Delivery of DNAs encoding secreted alkaline phosphatase and Cal/09 influenza virus hemagglutinin antigen generate high systemic circulating recombinant protein levels and antibody titres. …”
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5,7-Dihydroxyflavone acts on eNOS to achieve hypotensive effects in spontaneously hypertensive rats by Zi-Han Shen, Tongjie Ye, Baozhen Chen, Congchao Wan, Xiaolin Lu, Ting-Hsu Chen, Shuang Lin, Jia-Xin Ye, Liping Xie, Yaw-Syan Fu

“…This study will focus on the systemic antihypertensive mechanisms of 5,7-dihydroxyflavone from in silico simulations to in vivo validations. …”
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Roofing Highways With Solar Panels Substantially Reduces Carbon Emissions and Traffic Losses by Hou Jiang, Ning Lu, Jun Qin, Ling Yao, Xu Lian, Jijiang He, Tang Liu, Chenghu Zhou

“…Here, we combine solar PV output modeling with the global highway distribution and levelized cost of electricity to estimate the potential and economic feasibility of deploying highway PV systems worldwide. We also quantify its co‐benefits of reducing CO2 equivalent emissions and traffic losses (road traffic deaths and socio‐economic burdens). …”
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AI-Based Holistic Framework for Cyber Threat Intelligence Management by Arnolnt Spyros, Ilias Koritsas, Angelos Papoutsis, Panos Panagiotou, Despoina Chatzakou, Dimitrios Kavallieros, Theodora Tsikrika, Stefanos Vrochidis, Ioannis Kompatsiaris

“…Cyber Threat Intelligence (CTI) is an important asset for organisations to facilitate the safeguarding of their systems against new and emerging cyber threats. CTI continuously provides up-to-date information which enables the design and implementation of better security measures and mitigation strategies. …”
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Leucine-rich alpha-2-glycoprotein 1 deficiency suppresses ischemia–reperfusion injury-induced renal fibrosis by Naohito Okami, Hiromichi Wakui, Kengo Azushima, Tomohito Miyazawa, Eisuke Kubo, Shunichiro Tsukamoto, Mari Sotozawa, Shinya Taguchi, Shingo Urate, Kohei Ishiga, Sho Kinguchi, Tomohiko Kanaoka, Kouichi Tamura

“…Unilateral IRI was induced in C57BL/6J wild-type (WT) mice and systemic LRG1 knockout (KO) mice. In C57BL/6J WT mice, renal LRG1 mRNA expression was significantly elevated on the ischemia/reperfusion side compared to the sham side over a 28-day period. …”
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Transcriptome analysis of liver injury of fatty liver disease induced by ALDH2 deficiency by Ziying Xu, Yagang Gao, Zihui Yu, Rui Zhang, Ruikun Wang, Shang Li, Shuowen Wang, Bing Du, Ziyan Tian, Lijuan Huang, Zanbo Ding, Jing Yuan

“…Despite these insights, further research is needed to clarify the systemic effects on aldehyde metabolism and the full implications of Aldh2 deficiency and HiAlc Kpn in liver injury.…”
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Estimation of Soil Evaporation in Apple Orchards Based on Hydrogen and Oxygen Isotopes by Jialiang Huang, Yi Hua, Li Zhang, Chunxiu Yu, Kexin Chen, Linyun Gu, Yi Wu, Haoyan Wei, Min Li

“…These results are helpful to guide the scientific development of irrigation systems for apple orchards and provide a reference for enhancing apple yield and promoting the sustainable development of the apple industry.…”
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Methodology to Evaluate Dripper Sensitivity to Clogging due to Solid Particles: An Assessment by Rogério Lavanholi, Fabricio C. Oliveira, Antonio P. de Camargo, José A. Frizzone, Bruno Molle, Nassim Ait-Mouheb, Séverine Tomas

“…Emitter clogging is a major problem in microirrigation systems, which may result from the isolated or combined effects of physical, chemical, and biological agents. …”
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Clinical pathological characteristics and prognosis of orbital myeloid sarcoma-a single center retrospective study with 14 Chinese patients by Tianyi Zhou, Jiaqi Guan, Huijing Ye, Huasheng Yang

“…Early and consistent systemic chemotherapy can result in long-term survival.…”
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Research progress of Traditional Chinese Medicine nursing for patients with diabetes (糖尿病中医护理研究进展) by ZHENG Xiaoyan (郑晓艳), LI Jiayue (李佳玥), ZHANG Ying (张莹), GUO Peng (郭鹏)

“…Patients with diabetes will suffer from systemic vascular injury and various complications due to the continuous increase of blood sugar. …”
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Identification of Suitable Sites for Rainwater Harvesting Using AHP and GIS in the Middle and High Moulouya Basin, Morocco by Amiri Mustapha, Bouguelba Smail, Sbai Abdelkader, Ghzal Mohamed, Qadem Zohair, Salem Ali

“…In this study, a methodology integrating remote sensing data and geographic information systems was developed based on a model created in SIG software. …”
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Precision Analysis of Multi-Parameter Multi-Epoch Emitter Localization Radar in Three-Satellite Formation by Yiming Lian, Yuxuan Wu, Yaowen Chen, Xian Liu, Liming Jiang

“…This method enhances robustness and provides a viable strategy for addressing localization challenges caused by underdetermined systems of equations. Additionally, the results verify that an accumulated almanac element duration of 20 s ensures high positioning accuracy while maintaining a low computational cost. …”
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Association between physical activity, cardiometabolic risk factors and vitamin D in children and adolescents: a systematic review by Patricia Ribeiro Paes Corazza, Maiara Cristina Tadiotto, Derick Andrade Michel, Jorge Mota, Neiva Leite

“…Cardiometabolic risk factors included obesity, insulin resistance, systemic arterial hypertension and unfavorable changes in the lipid profile (low levels of high-density lipoprotein, elevated low-density lipoprotein and triglycerides). …”
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A Hybrid Transformer Architecture for Multiclass Mental Illness Prediction Using Social Media Text by Adnan Karamat, Muhammad Imran, Muhammad Usman Yaseen, Rasool Bukhsh, Sheraz Aslam, Nouman Ashraf

“…Therefore, machine learning and deep learning algorithms have been utilized in the existing literature for the detection of mental illness. However, current systems exhibit suboptimal performance primarily due to their reliance on traditional embedding techniques and generic language models to generate text embeddings. …”
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