Potential of Peroxisome Proliferator-Activated Receptor Gamma Antagonist Compounds as Therapeutic Agents for a Wide Range of Cancer Types by Jack D. Burton, David M. Goldenberg, Rosalyn D. Blumenthal

“…Most studies address agonist compounds, with substantially fewer reports on anticancer effects of PPARγ antagonists. In cancer model systems, some effects of PPARγ agonists were not inhibited by PPARγ antagonists, suggesting noncanonical or PPARγ-independent mechanisms. …”
Get full text

A high coverage reference transcriptome assembly of pea (<i>Pisum sativum</i> L.) mycorrhizal roots by A. M. Afonin, I. V. Leppyanen, O. A. Kulaeva, O. Y. Shtark, I. A. Tikhonovich, E. A. Dolgikh, V. A. Zhukov

“….), a widely cultivated crop and an important model for genetics, is capable of forming triple symbiotic systems consisting of the plant, AM fungi and nodule bacteria. …”
Get full text

Cadmium Sulfide Thin Films Deposited onto MWCNT/Polysulfone Substrates by Chemical Bath Deposition by M. Moreno, G. M. Alonzo-Medina, A. I. Oliva, A. I. Oliva-Avilés

“…These results show that the MWCNT/PSF composites with electric field-tailored MWCNTs represent a suitable option to be used as flexible conducting substrate for CdS thin films, which represents an important step towards the developing of flexible systems for photovoltaic applications.…”
Get full text

Integration of ordered porous materials for targeted three-component gas separation by Xue Jiang, Yu Wang, Hui Wang, Lu Cheng, Jian-Wei Cao, Jin-Bo Wang, Rong Yang, Dong-Hui Zhang, Run-Ye Zhang, Xiu-Bo Yang, Su-Hang Wang, Qiu-Yu Zhang, Kai-Jie Chen

“…We introduced a pore integration strategy of modularizing ordered pore structures with specific functions for on-demand assembly to deal with complex multi-component separation systems, which are unattainable by each individual pore. …”
Get full text

Syzygium aromaticum extract mediated, sustainable silver nanoparticle synergetic with heterocyclic antibiotic clarithromycin and their antimicrobial activities by Zehra Edis, Zehra Edis, Samir Haj Bloukh, Samir Haj Bloukh, Akram A. Ashames, Akram A. Ashames, Moawia M. Al-Tabakha, Moawia M. Al-Tabakha, Moyad J. S. A. Shahwan, Moyad J. S. A. Shahwan, Hamed Abu Sara, Hamed Abu Sara, Sai H. S. Boddu, Sai H. S. Boddu, Sohaib N. Khan, Sohaib N. Khan, Ibrahim Haj Bloukh, Maram Eladdasy, Somayeh Sadeghi, Haneen Alkubaisi, Iman Haj Bloukh, Nageeb A. G. M. Hassan, Nageeb A. G. M. Hassan

“…Clove extract derived nanoparticle synthesis is a promising method of combining therapeutics with metals at nanoscale. Such nanostructured systems in combination with the heterocyclic antibiotic clarithromycin could potentiate the action of plant extracts, decrease drug side effects and improve antimicrobial activity. …”
Get full text

Self-Supervised Chinese Ontology Learning from Online Encyclopedias by Fanghuai Hu, Zhiqing Shao, Tong Ruan

“…We explore the three largest online Chinese encyclopedias for ontology learning and describe how to transfer the structured knowledge in encyclopedias, including article titles, category labels, redirection pages, taxonomy systems, and InfoBox modules, into ontological form. …”
Get full text

Mitigating CaCO3 crystal nucleation and growth through continuous ion displacement via alternating electric fields by Yiming Liu, Minhao Xiao, Xiaochuan Huang, Jane Park, Matthew E. Hoffman, Yuren Feng, Alicia Kyoungjin An, Qilin Li, Eric M. V. Hoek, David Jassby

“…Overall, the technique has potential for preventing mineral crystal formation in heat exchangers and many other industrially relevant systems.…”
Get full text

Optimizing photovoltaic power plant forecasting with dynamic neural network structure refinement by Dácil Díaz-Bello, Carlos Vargas-Salgado, Manuel Alcazar-Ortega, David Alfonso-Solar

“…Abstract Reliable prediction of photovoltaic power generation is key to the efficient management of energy systems in response to the inherent uncertainty of renewable energy sources. …”
Get full text

Occult Langerhans Cell Histiocytosis Presenting with Papillary Thyroid Carcinoma, a Thickened Pituitary Stalk and Diabetes Insipidus by Michael S. Gordon, Murray B. Gordon

“…This case illustrates that one must be vigilant for extrapituitary manifestations of systemic diseases to diagnose the etiology of TPS. …”
Get full text

Ischemic Heart Disease Prognosis: A Hybrid Residual Attention-Enhanced LSTM Model by D. Cenitta, R. Vijaya Arjunan, Ganesh Paramasivam, N. Arul, Anisha Palkar, Krishnaraj Chadaga

“…The proposed HRAE-LSTM outperforms existing cardiac disease prediction systems by 97.7 % with the UCI dataset, respectively.…”
Get full text

Assessments of Wind-Energy Potential in Selected Sites from Three Geopolitical Zones in Nigeria: Implications for Renewable/Sustainable Rural Electrification by Joshua Olusegun Okeniyi, Olayinka Soledayo Ohunakin, Elizabeth Toyin Okeniyi

“…However, econometrics of electricity power simulation at different hub heights of low wind-speed turbine systems showed that the cost of electric-power generation in the three study sites was converging to affordable cost per kWh of electric energy from the wind resource at each site. …”
Get full text

Healthcare utilisation by pregnant patients with asthma in South Korea: a cohort study using nationwide claims data by Deog Kyeom Kim, Chang-Hoon Lee, Ho Il Yoon, Jae-Joon Yim, Eun Jin Jang, Jimin Kim, Yun Jung Kim, Seongmi Choi, Joon-Ho Lee

“…Among those with asthma requiring healthcare utilisation, 6.9% were hospitalised and treated with systemic steroids and short-acting β2-agonists during pregnancy. …”
Get full text

Who does technology serve? A critical analysis of sociocultural factors shaping opportunities, practices and barriers faced by a smallholders in south-western Colombia by Marcela Ramos, Natalia Triana, Stefan Burkart, Jhon Freddy Gutiérrez, Diana María Gutiérrez-Zapata, Alejandro Ruden, Lady Sepúlveda, Brian Barrett

“…Specifically, improved forages, silvopastoral systems and new practices, such as the implementation of rotational pasturing, have been promoted as relevant new approaches. …”
Get full text

Significance of Circulating and Crevicular Matrix Metalloproteinase-9 in Rheumatoid Arthritis-Chronic Periodontitis Association by Isabela Silosi, Manole Cojocaru, Lili Foia, Mihail Virgil Boldeanu, Florin Petrescu, Petra Surlin, Viorel Biciusca

“…The purpose of this study was to evaluate the utility of determining systemic and crevicular levels of metalloproteinase-9 (MMP-9) as potential biomarkers for association between RA and CP. …”
Get full text

Production, Characterization, and In Vitro Antifungal Evaluation of Itraconazole-Loaded Fibrous Sheets Prepared by Electrospinning with a Factorial Design by Emőke-Margit Rédai, Orsolya Péterfi, Attila Levente Gergely, Enikő Barabás, Andrada Pintea, Paula Antonoaea, Robert-Alexandru Vlad, Nicoleta Todoran, Cornelia-Titiana Cotoi, Adriana Ciurba, Emese Sipos

“…Itraconazole (ITZ) is a broad-spectrum triazole antifungal agent suitable for the treatment of superficial and systemic mycoses. This study aimed to formulate, characterize, and evaluate the in vitro antifungal performance of single-jet electrospun itraconazole-loaded polyvinylpyrrolidone-based fibers. …”
Get full text

Gastrointestinal Bleeding in Antithrombotic Therapy in Patients with Coronary Heart Disease: Risk Factors, Pathogenesis and Treatment by N. S. Lapina, A. A. Alekseeva, A. D. Vershinina, N. S. Khruleva, F. N. Muradova, L. Y. Koroleva

“…Pathogenesis of GIB in the course of antithrombotic therapy is associated with systemic hypocoagulation and local damaging effects of these drugs. …”
Get full text

Controlling Factors of Artificial Irregularities Triggered by Chemical Release at Low Latitude Ionosphere by Jing‐Fan Gao, Zheng‐Wen Xu, Li‐Xin Guo, Kun Xue, Hai‐Sheng Zhao

“…It is a helpful tool to both recognize the physical mechanism for modeling space weather and mitigate adverse effects on technological systems. Based on the well‐developed instability simulation, the rate of change of total electron content index (ROTI) theory is employed as a diagnosis method in this paper. …”
Get full text

Targeting C-Reactive Protein in Inflammatory Disease by Preventing Conformational Changes by J. R. Thiele, J. Zeller, H. Bannasch, G. B. Stark, K. Peter, S. U. Eisenhardt

“…Recent findings brought up the idea of CRP to be not only a systemic marker but also a mediator of inflammation. …”
Get full text

Limiting the development of anti-cancer drug resistance in a spatial model of micrometastases by Ami B. Shah, Katarzyna A. Rejniak, Jana L. Gevertz

“…While chemoresistance in primary tumors is well-studied, much less is known about the influence of systemic chemotherapy on the development of drug resistance at metastatic sites. …”
Get full text

Fiber-tip photonic crystal for real-time referenced biosensing in serum by Mathias Dolci, Paco Dreverman, Mildred S. Cano-Velázquez, Arthur L. Hendriks, Emiel Veth, P.J. van Veldhoven, Andrea Fiore, Peter Zijlstra

“…These referenced fiber-tip PhC biosensors may pave the way for fluidic integrated systems in environmental, industrial, and healthcare applications, and open up the possibility of biosensing in the human body by integrating them into catheters.…”
Get full text