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67781
Screening of SIRT2 inhibitors from natural product databases using computer-aided drug design and molecular dynamics simulation
Published 2025-01-01“…The Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (YaTCM) has been thoroughly explored to identify SIRT2 inhibitors, and the discovered compounds have been validated using molecular dynamics simulation. …”
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67782
Study on Deformation and Stability of Rock-Like Materials Retaining Structure during Collaborative Construction of Super-Adjacent Underground Project
Published 2021-01-01“…The results show that due to the difference between the supporting systems of rock-like materials on both sides and other reasons, the upper part of the retaining structure and the limited soil in the adjacent area tilt greatly to one side at the same time, and the surface settlement in the limited soil area also increases with the increase of the excavation depth of the foundation pit. …”
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67783
Demystifying early childhood computational thinking: An umbrella review to upgrade the field
Published 2024-12-01“…The Bee‐Bot and various LEGO kits were prevalent among CT learning tools, with interfaces ranging from physical buttons to hybrid systems. Efficacy was noted in tangible activities like unplugged applications and robotics in enhancing concrete understanding and competencies in coding, CT, and spatial skills. …”
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67784
Non-melanoma skin cancer treated with hypofractionated 192—Ir contact brachitherapy: a single institution series
Published 2025-01-01“…Therapeutic management of NMSC includes a variety of options, such as surgery, radiotherapy, and topical or systemic treatments. High-dose fractionated contact brachytherapy (c-HDR-BRT) is a viable therapeutic option for treating NMSCs.MethodsAt our center, we treated 39 patients with BCC or SCC, with a total of 46 lesions, treated with c-HDR-BRT. …”
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67785
Doppler weather radars as a game changer in desert locust swarm tracking
Published 2024-12-01“…Findings reveal the potential to establish early warning systems with lead times of 5–7 h and spatial coverage of approximately 100 km, empowering timely mitigation efforts. …”
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67786
A critical review of compensation converters for capacitive power transfer in wireless electric vehicle charging circuit topologies
Published 2025-04-01“…This review paper proposed various designs of compensation circuit topologies to achieve the effectiveness of the CPT scheme for Wireless Power Transfer (WPT) systems.…”
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67787
Is in situ simulation in emergency medicine safe? A scoping review
Published 2022-07-01“…The possible negative impact of ISS on real ED patients was assessed in two studies (2.5%), through a questionnaire and not through patient outcomes.Conclusion Most studies use ISS for systems-based or education-based applications. Patient safety during ISS is often evaluated in the context of identifying or mitigating LSTs and rarely on the potential impact and risks to patients simultaneously receiving care in the ED. …”
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67788
Enhancing Environmental Control in Broiler Production: Retrieval-Augmented Generation for Improved Decision-Making with Large Language Models
Published 2025-01-01“…The growing global demand for animal protein, particularly chicken meat, challenges poultry farming to adapt production systems through the adoption of digital technologies. …”
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67789
Exploring aneuploidies in two-center isolated bovine embryonic stem cell lines: Implications for cultured meat production
Published 2025-06-01“…This research underscores the necessity for systematic monitoring and optimizing culture conditions to mitigate genomic instabilities, ensuring the safe application of bESCs in sustainable food systems. Our findings pave the way for future innovations in clean food processing and utilising new food ingredients.…”
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67790
A multi-band dual-layer encoded microwave absorber with angle selectivity
Published 2025-03-01“…To meet the pressing demands of modern wireless communication systems for controllable, angle-selective, transparent, and multi-band microwave absorbers, the designed absorber consists of upper and lower transparent coded structures with an intermediate air layer.Further analysis of the absorber’s operating principle revealed that under normal incidence conditions, the absorber exhibits four resonant peaks at 13.1 GHz, 25.0 GHz, 33.5 GHz, and 35.6 GHz, with absorption rates exceeding 99.8 %.Ultimately, we fabricated samples and measured their absorption performance within the frequency range of 0–26 GHz under experimental conditions. …”
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67791
Adaptive Traffic Signal Control Model on Intersections Based on Deep Reinforcement Learning
Published 2020-01-01“…Controlling traffic signals to alleviate increasing traffic pressure is a concept that has received public attention for a long time. However, existing systems and methodologies for controlling traffic signals are insufficient for addressing the problem. …”
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67792
Detection of The TNFSF Members BAFF, APRIL, TWEAK and Their Receptors in Normal Kidney and Renal Cell Carcinomas
Published 2011-01-01“…In advanced renal cell carcinoma (RCC), surgery combined with systemic chemotherapy and immunotherapy have had limited effectiveness. …”
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67793
ACCIDENTS AND OCCUPATIONAL ILLNESS ASSESSMENTS FOR 400/220/110/20 kV URECHESTI POWER SUBSTATION
Published 2023-12-01“…In response to these social phenomena, public institutions, economic agents in the industry, researchers in the disciplines involved have proposed methods of risk forecasting, aimed at developing prevention and protection systems that improve the risk management process. …”
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67794
Occurrence, distribution, and potential ecological risks of psychoactive substances in the mangrove environment, Hainan Island of South China
Published 2025-01-01“…Conclusions Generally, this study provided valuable insights into the environmental occurrence, spatial variations, and ecological risks of PSs in mangrove wetlands systems for the first time, serving as a foundation for understanding their influence on the mangrove ecosystem, which may aid in protection of those unique and vulnerable areas.…”
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67795
Test setup for analyzing the electrical resistance during fatigue loading for metastable austenite AISI 304L and its diffusion-brazed joints
Published 2025-03-01“…To quantify and compensate the effects of geometry, temperature, and deformation-induced austenite-martensite transformation on the electrical resistance during fatigue loading, a complex experimental setup was developed which includes several measurement systems. The combination of strain measurement and potential drop enables a direct transfer of measured strain to electrical resistance. …”
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67796
Interleukin 15‐Presenting Nanovesicles with Doxorubicin‐Loaded Ferritin Cores for Cancer Immunochemotherapy
Published 2025-01-01“…However, IL15 supplementary therapy encounters challenges such as systemic inflammation and non‐specific stimulation of cancer cells. …”
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67797
A Case of Simultaneous, Biopsy-Proven, Classic, ANCA-Positive Wegener's Granulomatosis and Anti-GBM Disease, but without Detectible Circulating Anti-GBM Antibodies
Published 2010-01-01“…Wegener's granulomatosis (WG) is a systemic, necrotizing, granulomatous vasculitis of unknown etiology. …”
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67798
The impact of refuges on Citrus orchards associated with arthropods in different agroecosystem in Malang, Indonesia
Published 2025-12-01“…Temperature and wind speed significantly affect insect abundance. Polyculture systems have higher species richness and diversity indices than monocultures, thus supporting higher species diversity and more stable ecosystems.…”
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67799
A Rare Cause of Secondary Amyloidosis: Common Variable Immunodeficiency Disease
Published 2012-01-01“…Here, we present a case of systemic amyloidosis that developed secondary to the common variable immunodeficiency disease causing recurrent infections in a young female patient. …”
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67800
Seeing beyond words: nanotechnology in hepatocellular carcinoma - a bibliometric study
Published 2025-01-01“…The research mainly focused on drug delivery systems and apoptosis, highlighting significant advancements in utilizing nanotechnology for HCC treatment.ConclusionThis bibliometric study underscores the critical role of nanotechnology in advancing the diagnosis and treatment of hepatocellular carcinoma, with a particular emphasis on drug delivery and apoptosis. …”
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