Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer by Luca Mastracci, Patrizio Castagnola, Elia Bari, Francesca Ferrera, Tiziana Altosole, Sara Perteghella, Pierluigi Mauri, Rossana Rossi, Giulia Passignani, Martina Galati, Giuseppina Iliana Astone, Maddalena Mastrogiacomo, Daniela Fenoglio, Dario Di Silvestre, Maria Luisa Torre, Gilberto Filaci

“…Cancer dimensions/survival time were monitored, while, at the molecular level, system biology approaches based on graph theory and experimental proteomic data were performed.Results SFNs were efficiently in vitro uptaken by cancer and dendritic cells. …”
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Desain Layanan E-Surat untuk Desa Waru Barat, Pamekasan, Madura menggunakan QR-Code by Wahyudi Agustiono, Intan Rofika Putri, Devie Rosa Anamisa

“…Despite these practical implication, the contribution of this research, especially to the IT discipline which could be adopted in the future study, is the system architecture and e-certificate application along with the algorithm for generating unique QR Code to ensure the security and validity of the document.            …”
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Cohort profile: the Western Cape Pregnancy Exposure Registry (WCPER) by Landon Myer, Amy L Slogrove, Ushma Mehta, Mary-Ann Davies, Max Kroon, Greg Petro, Alexa Heekes, Andrew Boulle, Karen Fieggen, Chantal Stewart, Ayesha Osman, Natasha Rhoda, Emma Kalk, Florence Phelanyane, Jonathan Euvrard, Stefan Gebhardt, Kim Anderson

“…Analysis of key obstetric and neonatal health indicators derived from the PER are consistent with the aggregate data in the District Health Information System.Future plans This represents significant infrastructure, able to address clinical and epidemiological concerns in a low/middle-income setting.…”
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Application of fuzzy logic in decision-making process for relocation of floating net cages in river fish farming by R. Pramana, B.Y. Suprapto, Z. Nawawi

“…This study aims to develop an early warning system for water quality and create a decision-making program as a reference for fishermen to relocate floating net cages when the river water quality deteriorates.METHODS: The device was tested at 39 locations within a radius of approximately 3400 meters, and the distance between locations varied between 55 and 334 meters. …”
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Spatial distribution and determinants of children ever born among reproductive age women in Ethiopia: spatial and multilevel analysis of 2019 mini Ethiopian demographic health surv... by Ahmed Fentaw Ahmed, Bezawit Adane, Tilahun Degu Tsega, Mekides Nigusu, Kalaab Esubalew Sharew, Abebaw Molla, Mulugeta Tesfa

“…STATA and Aeronautical Reconnaissance Coverage Geographic Information System (ArcGIS) 10.8 software was used. The primary outcome, CEB, was categorized as “low” if fewer than five children were born and “high” if five or more children were born. …”
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Intervertebral Disc Degeneration in Long-Term Postoperative Patients with Adolescent Idiopathic Scoliosis: MRI Evaluation 34-51 Years after Surgery and its Changes during Middle an... by Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Yasushi Iijima, Yoshiaki Torii, Jun Ueno, Atsuhiro Yoshida, Ken Tomochika, Sumihisa Orita, Yawara Eguchi, Kazuhide Inage, Yasuhiro Shiga, Junichi Nakamura, Yusuke Matsuura, Takane Suzuki, Hisateru Niki, Seiji Ohtori, Shohei Minami

“…DD was evaluated using the Pfirrmann grading system. Various factors, such as surgical levels, sagittal alignment, and PROMs, were analyzed for their association with DD. …”
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Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

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Physico-Chemical Properties of Granular Sorbents Based on Natural Bentonite Modified by Polyhydroxocations of Aluminum and Iron (III) by Co-Precipitation by Bakytgul Kussainova, Gaukhar Tazhkenova, Ivan Kazarinov, Marina Burashnikova, Raigul Ramazanova, Yelena Ivashchenko, Bekzat Saurbayeva, Batima Tantybayeva, Ainur Seitkan, Gulsim Matniyazova, Khalipa Sadiyeva, Aisha Nurlybayeva, Aidana Bazarkhankyzy

“…Then the sorption process begins to proceed in a mixed diffusion mode, when it limits both the external diffusion factor and the internal diffusion factor (the diffusion of the sorbent to the active centers through the system of pores and capillaries). To determine the contribution of the chemical stage to the rate of adsorption of bichromate and arsenate anions and nickel(II) cations with the studied granular sorbents, kinetic curves were processed using the equations of chemical kinetics (pseudo-second-order model). …”
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Research on the Seismic Response Law of Complete Morphology of Butted Well Salt Cavern for Large-Scale Underground Energy Storage by Haitao Li, Dewen Zheng, Kang Li, Qiqi Wanyan, Lina Ran, Yanxia Kou, Song Bai, Jianan Wu, Jianchao Jia, Yunfei Wen, Yuanqing Wang, Hongyan Xing, Kuoyuan Zhu, Jingen Deng

“…Based on 3D seismic data, well logging data, and measured cavity shape parameters from the Yexian salt mine region in Henan Province, China, a geological model and observation system were established. The seismic response characteristics of the butted well salt cavern model, encompassing five distinct morphological attributes such as cavity spacing, cavity diameter, cavity height, sediment height, and horizontal connection channel height, were thoroughly investigated. …”
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Global Mountain Safeguard Research (GLOMOS): Five Years Into Action by Stefan Schneiderbauer, Paola Fontanella Pisa, Lina Rodriguez, Navneet Kumar, Federica Romagnoli, Dipesh Chapagain, Jörg Szarzynski

“…GLOMOS represents the only mountain-focused research program within the global system of the UNU. With a focus on risks in mountains, and considering the complex interrelations and interdependences of upland and lowland areas, GLOMOS fosters the development of sustainable and resilient mountain communities. …”
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Tropical upper-tropospheric trends in ozone and carbon monoxide (2005–2020): observational and model results by L. Froidevaux, D. E. Kinnison, B. Gaubert, M. J. Schwartz, N. J. Livesey, W. G. Read, C. G. Bardeen, J. R. Ziemke, J. R. Ziemke, R. A. Fuller

“…The MLS zonal mean CO UT trend for 20° S–20° N is <span class="inline-formula">−0.25</span> <span class="inline-formula">±</span> 0.30 % yr<span class="inline-formula">⁻¹</span>, while the corresponding CAM-chem trend is 0.0 <span class="inline-formula">±</span> 0.14 % yr<span class="inline-formula">⁻¹</span> when anthropogenic emissions are taken from the Community Emissions Data System (CEDS) version 2. The CAM-chem simulation driven by CAMS-GLOB-ANTv5 emissions yields a tropical mean CO UT trend of 0.22 <span class="inline-formula">±</span> 0.19 % yr<span class="inline-formula">⁻¹</span>, in contrast to the slightly negative MLS CO trend. …”
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Ice-proximal sea ice reconstruction in the Powell Basin, Antarctica, since the Last Interglacial by W. W. Khoo, J. Müller, J. Müller, J. Müller, O. Esper, W. Xiao, C. Stepanek, P. Gierz, G. Lohmann, G. Lohmann, G. Lohmann, W. Geibert, J. Hefter, G. Mollenhauer, G. Mollenhauer, G. Mollenhauer

“…<p>In Antarctica, the presence of sea ice not only plays a critical role in the climate system but also contributes to enhancing the stability of the floating ice shelves. …”
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Influencing factors of the participation of patients with severe mental disorders in community health service management by Shiming Li, Yingying Ji, Queping Yang, Ying Jiang, Qitao Yin, Haohao Zhu

“…ObjectiveThis study aimed to explore the participation of patients with severe mental disorders in community health service management and its influencing factors in Wuxi.MethodsThe data of patients with severe mental disorders were extracted from the Jiangsu Provincial Management System between 2019 and 2021. The participation of patients in community health service management was analyzed. …”
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A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024 by Saijilafu, Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu

“…With 17 publications, the University of California System led the institutional rankings. A thorough keyword analysis revealed pivotal themes in the field, encompassing the optic nerve, gene expression, CST integrity and regeneration, diffusion tensor imaging, myelin-associated glycoproteins, inhibitors of neurite outgrowth, and methods of electrical and intracortical microstimulation.ConclusionThis investigation provides a bibliometric analysis of CST regeneration, underscoring the significant contribution of the United States to this field. …”
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Risk Factors for Intrauterine Device Malposition by Ann C. Frisse, Jay B. Louik, Isha A. Kachwala, Haotian Wu, Nicole Felix, Thammatat Vorawandthanachai, Karina Avila, Nerys C. Benfield

“…Methods: We performed a retrospective cohort study of IUD users with ultrasounds performed between July 2014 and July 2017 within a large urban medical system. Our primary outcome was IUD malposition. We used Fisher’s Exact Test and Wilcoxon Rank Sum Test to compare clinical characteristics between patients with malpositioned and non-malpositioned IUDs. …”
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Development of a Recombinant Fusion Vaccine Candidate Against Lethal <i>Clostridium botulinum</i> Neurotoxin Types A and B by Eun-Sun Choi, Seong-Wook Pyo, So-Hyeon Kim, Jun-Ho Jeon, Gi-Eun Rhie, Mi-Ran Yun, Hwajung Yi, Yoon-Seok Chung

“…Background: Botulinum neurotoxins (BoNTs), produced by <i>Clostridium botulinum</i>, are potent protein toxins that can cause botulism, which leads to death or neuroparalysis in humans by targeting the nervous system. BoNTs comprise three functional domains: a light-chain enzymatic domain (LC), a heavy-chain translocation domain (HC_N), and a heavy-chain receptor-binding domain (HC_C). …”
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<i>Rubus idaeus RiACS1</i> Gene Is Involved in Ethylene Synthesis and Accelerates Fruit Ripening in <i>Solanum lycopersicum</i> by Tiemei Li, Wenjiao Xin, Hang Zhang, Jiarong Jiang, Kunmiao Ding, Mengyu Liu, Nanyan Li, Guohui Yang

“…The subcellular localization analysis of the RiACS1 protein in the tobacco transient expression system revealed that the RiACS1-GFP fusion protein was mainly located in the nucleus. …”
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Enhanced energy storage performance in Ag(Nb,Ta)O3 films via interface engineering by Xiao Zhai, Jun Ouyang, Weijie Kuai, Yinxiu Xue, Kun Wang, Nengneng Luo, Hongbo Cheng, Hanfei Zhu, Chao Liu, Limei Zheng

“…An extremely large breakdown field Eb∼4.3 MV/cm is achieved, being the highest value up to date in the niobate system. A high recoverable energy density Wrec∼62.3 J/cm3 and a decent efficiency η∼72.3% are obtained, much superior to that of the Ag(Nb,Ta)O3 monolayer film (Wrec∼46.4 J/cm3 and η∼80.3% at Eb∼3.3 MV/cm). …”
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Molecular testing stratifies the risk of structural recurrence in high risk differentiated thyroid cancer: a retrospective cohort study by Jie Liu, Wensi Gao, Xiong Zheng, Shuping Wu, Yi Shi, Feng Wang, Yu Wu

“…BackgroundHigh-risk differentiated thyroid cancer in 2015 American Thyroid Association risk stratification system (ATA-RSS) exhibits a significantly increased probability of recurrence and poor outcomes. …”
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MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis by Huifang Bai, Qianqian Dang, Guoliang Chen, Lingfeng Xie, Saining Wang, Ning Jiang, Xiaoxia Wu, Shuyan Zhang, Xuelin Wang

“…Abstract Trichinella spiralis (T. spiralis) has been reported to induce inflammation, which can cause immune system dysregulation. Myeloid differentiation primary response gene 88 (MyD88) is implicated in inflammation signalling pathways. …”
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