Peroxidase (POD) Mimicking Activity of Different Types of Poly(ethyleneimine)-Mediated Prussian Blue Nanoparticles by Udara Bimendra Gunatilake, Briza Pérez-López, Maria Urpi, Judit Prat-Trunas, Gerard Carrera-Cardona, Gautier Félix, Saad Sene, Mickaël Beaudhuin, Jean-Charles Dupin, Joachim Allouche, Yannick Guari, Joulia Larionova, Eva Baldrich

“…Thus, the elucidation of the catalytic POD mimicry of these systems is of significant scientific interest but has not been investigated in depth yet. …”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…Results In this study, we utilized the SpyTag (ST)/SpyCatcher (SC) bioconjugation system to couple OMV and SARS-CoV-2 RBD in vitro. …”
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Diagnostic criteria for asthenic accommodative asthenopia in patients with computer vision syndrome by I.G. Ovechkin, I.S. Gadzhiev, Kozhukhov A.A, E.I. Belikova

“…</i> </p> <p> <i><b>Conclusion</b>: asthenic accommodative asthenopia is characterized by specific clinical functional and diagnostic criteria identified by both conventional and modern methods of the examination of visual accommodative system. These criteria can be recommended to assess the efficacy of preventive and therapeutic measures.…”
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Biochanin A Reduces Inflammatory Injury and Neuronal Apoptosis following Subarachnoid Hemorrhage via Suppression of the TLRs/TIRAP/MyD88/NF-κB Pathway by Ling-yun Wu, Zhen-nan Ye, Zong Zhuang, Yongyue Gao, Chao Tang, Chen-hui Zhou, Chun-xi Wang, Xiang-sheng Zhang, Guang-bin Xie, Jing-peng Liu, Meng-liang Zhou, Chun-hua Hang, Ji-xin Shi

“…Neurobehavioral function was evaluated via the modified water maze test and modified Garcia neurologic score system. Thus, we confirmed that BCA markedly decreased the activated level of TLRs/TIRAP/MyD88/NF-κB pathway and the production of cytokines. …”
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Decades of leopard coexistence in the Himalayas driven by ecological dynamics, not climate change by Paras Bikram Singh, Pradip Saud, Prakash Chandra Aryal, Pawan Rai, Jeff R. Muntifering, Huijian Hu, Ajay Karki, Yiming Hu, Kumar P. Mainali

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Penentuan Guru Berprestasi Menggunakan Metode Analytical Hierarchy Process (AHP) dan VIseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) by Kharis Hudaiby Hanif, Anton Yudhana, Abdul Fadlil

“…The stages of the research are data collection, determining the criteria weights, the AHP method, the VIKOR method, manual and system calculations. There are four criteria used, namely pedagogic, personality, social, and professional. …”
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Obstetric risk profiles and causes of death: Estimating their association with cesarean sections among maternal deaths in Mexico. by Pablo Martínez-Garrido, Jimena Fritz, Alejandra Montoya, Mayra J Garza, Héctor Lamadrid-Figueroa

“…An algorithm was developed to extract the Robson Ten Group Classification System from clinical summaries text, facilitating a nuanced analysis of C-section rates. …”
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Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound databa... by Xuan Li, Minwen Huang, Yue-Mei Zhao, Wenxin Liu, Nan Hu, Jie Zhou, Zi-Yi Wang, Sheng Tang, Jian-Bin Pan, Hian Kee Lee, Yao-zuo Yuan, Taijun Hang, Hai-Wei Shi, Hongyuan Chen

“…A high concentration of phosphate buffer mobile phase was used in the first-dimensional LC system to get the components well separated. For efficient and high-accuracy screening of CMS, a targeted method based on a self-constructed high resolution (HR) mass spectrum database of CMS components was established. …”
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Vagal Blocking Improves Glycemic Control and Elevated Blood Pressure in Obese Subjects with Type 2 Diabetes Mellitus by S. Shikora, J. Toouli, M. F. Herrera, B. Kulseng, H. Zulewski, R. Brancatisano, L. Kow, J. P. Pantoja, G. Johnsen, A. Brancatisano, K. S. Tweden, M. B. Knudson, C. J. Billington

“…Twenty-eight subjects were implanted with a VBLOC device (Maestro Rechargeable System) at 5 centers in an open-label study. Effects on weight loss, HbA1c, fasting blood glucose, and BP were evaluated at 1 week to 12 months. …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca²⁺concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic>&lt;0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic>&lt;0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic>&lt;0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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Engagement féminin en Kabylie et intersection des revendications (1980-2001). Dominations, expériences et négociations identitaires by Margherita Rasulo

“…The “Black Spring” led to a reaffirmation of the patriarchal system, including in the structuring of the protest movement of this period.…”
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Association between different modalities of opioid use disorder-related care delivery and opioid use disorder-related patient outcomes: A retrospective cohort study by Nahiyan Bin Noor, George Pro, Mahip Acharya, Hari Eswaran, Corey J. Hayes

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Basic Characteristics of Ionic Liquid-Gated Graphene FET Sensors for Nitrogen Cycle Monitoring in Agricultural Soil by Naoki Shiraishi, Jian Lu, Fatin Bazilah Fauzi, Ryo Imaizumi, Toyohiro Tsukahara, Satoshi Mogari, Shosuke Iida, Yusuke Matsukura, Satoshi Teramoto, Keisuke Yokoi, Izumi Ichinose, Mutsumi Kimura

“…Then, we analyzed their transfer characteristics in our developed N₂O evaluation system using different concentrations of N₂O and air. …”
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Socially interactive industrial robots: a PAD model of flow for emotional co-regulation by Fabrizio Nunnari, Dimitra Tsovaltzi , Matteo Lavit Nicora , Matteo Lavit Nicora , Sebastian Beyrodt , Pooja Prajod , Lara Chehayeb , Ingrid Brdar , Antonella Delle Fave , Luca Negri , Elisabeth André, Patrick Gebhard , Matteo Malosio 

“…Additional results from a first evaluation of the overall system (Study 2, N = 12) align with these findings and provide support for the use of socially interactive industrial robots to support wellbeing, job satisfaction, and involvement, while reducing unproductive emotional experiences and their regulation.…”
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Regulation of Paneth cell-specific genes in COVID-19 patients and SARS-CoV-2-infected mice by quantification of mRNA from exfoliated cells in stool samples by Gill Diamond, Erika L. Figgins, Denny Gao, Tanya O. Robinson, Kenneth Wilson, Jon D. Gabbard, Charles D. Anderson, Lalit Batra, Chithra Sreenivasan, Jian Zheng, Uyen Do, Braden Mulcahy, Lisa K. Ryan, Nathaniel McLaughlin, Anna H. Owings, Neha Dhaliwal, Haley B. Williams, T. Grant Wichman, Michelle Galeas-Pena, Sarah C. Glover

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Cellular rejuvenation protects neurons from inflammation-mediated cell death by Sienna S. Drake, Abdulshakour Mohammadnia, Aliyah Zaman, Christine Gianfelice, Kali Heale, Adam M.R. Groh, Elizabeth M.-L. Hua, Matthew A. Hintermayer, Yuancheng Ryan Lu, David Gosselin, Stephanie Zandee, Alexandre Prat, Jo Anne Stratton, David A. Sinclair, Alyson E. Fournier

“…Summary: In multiple sclerosis (MS), inflammation of the central nervous system results in demyelination, neuroaxonal injury, and cell death. …”
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Understanding secondary hypogammaglobulinemia and its implications for cancer prognosis in children: A retrospective cohort study by Ana Lucía Guzmán, Isabella Villamil, Sofía Martínez-Betancur, Oriana Arias-Valderrama, Jacobo Triviño-Arias, Jessica Largo, Viviana Lotero, Alexis Franco, Ximena Castro, Pamela Rodríguez, Luz Angela Urcuqui, Diego Medina, Manuela Olaya

“…Immunodeficiencies are disturbances in the immune system that can affect cell function, quantity, or both. …”
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Producing hydrogen from biomass and seawater using immobilized carbon nitride photocatalysts by Ana L. Machado, Ricardo A. Oliveira, Goran Dražić, Joana C. Lopes, Cláudia G. Silva, Joaquim L. Faria, Maria J. Sampaio

“…Despite a slight decrease in H₂ evolution compared with the powdered catalysts, the use of immobilized photocatalyst exhibited remarkable stability in both ultrapure water and seawater, maintaining its performance across multiple reuse cycles. The photocatalytic system demonstrated remarkable efficiency for H₂ production, avoiding phases separation processes, promotes the transition to continuous flow reactors and preserve freshwater resources.…”
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Perbandingan Algoritme Machine Learning untuk Memprediksi Pengambil Matakuliah by Fitra A. Bachtiar, Indra K. Syahputra, Satrio A. Wicaksono

“…Thus, there is a need to build a system that can predict students taking courses. However, there are many algorithms that can be used for the prediction. …”
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Current trends of unicompartmental knee arthroplasty (UKA): choosing between robotic-assisted and conventional surgeries and timing of procedures by Kelvin S. C. Cheung, Kai Chun Augustine Chan, Amy Cheung, Ping Keung Chan, Michelle Hilda Luk, Kwong Yuen Chiu, Henry Fu

“…Primary outcomes included utilization of UKA compared to TKA and percentage utilization of different UKA systems, namely, conventional, Mako, and Cori/Navio systems, from 2021–2023. …”
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