Clinical significance of HER2 in urothelial carcinoma and analysis of its correlation with glycolytic metabolic characteristics by Andong Guo, Andong Guo, Chenrui Wu, Jishuang Cao, Kejia Zhu, Kejia Zhu, Sentai Ding, Sentai Ding

“…HER2 status was determined using a standardized scoring system from the 2021 Clinical Pathological Expert Consensus on HER2 Testing in UC, China. …”
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Structural, magnetic, and optical characteristics of undoped and chromium, iron, cobalt, copper, and zinc doped nickel oxide nanopowders by Farzaneh Asaldoust, Khosro Mabhouti, Akbar Jafari, Maryam Taleb-Abbasi

“…In addition, doping of Cr, Fe, Co, Cu, and Zn into the NiO system did not induce any other secondary phase. Moreover, the estimation of the crystalline size for the pristine and doped samples was carried out using the Debye-Scherrer formula, yielding values ranging from 16 to 28 nm which is deemed suitable for the study of doping effects. …”
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Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin by A. Valle, J. Sastre-Serra, C. Pol, A. M. Miró, J. Oliver, P. Roca

“…Proteins involved in other cellular functions such as stress response, cytosqueleton remodeling and proteins belonging to ubiquitin-proteasome system, were also identified. Furthermore, leptin-treated cells showed a substantial uptake of the serum carrier proteins albumin and alpha-2-HS-glycoprotein. …”
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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…The collected data will be linked to secondary sources such as cancer registries and National Health Insurance Service data to provide a comprehensive analysis of the impact of hereditary cancer on health and survival.Ethics and dissemination The study protocol was approved by all the Ethics Committees: the National Cancer Center IRB (NCC2023-0179), the Samsung Medical Center IRB (SMC2023-09-057), the Yonsei University Health System, Severance Hospital IRB (4-2023-0627), the Hanyang University Guri Hospital IRB (GURI2023-08-021) and the Keimyung University IRB (DSMC IRB 2024-05-048). …”
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CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses by Alice Bergamini, Barbara Camisa, Attilio Bondanza, Fabio Ciceri, Chiara Bonini, Monica Casucci, Beatrice Greco, Camilla Bove, Silvia Arcangeli, Laura Falcone, Rita El Khoury, Anna De Lucia

“…To this aim, we took advantage of immunodeficient mice reconstituted with a human immune system (HuSGM3) and engrafted with the B-cell acute lymphoblastic leukemia cell line NALM-6, a model that allows to thoroughly study efficacy and toxicity profiles of CD19 CAR-T cell products.Results CD4 CAR-T cells showed superior proliferation and activation potential, which translated into stronger stimulation of myeloid cells, the main triggers of adverse events. …”
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Enhanced phosphorus weathering contributed to Late Miocene cooling by Yi Zhong, Zhiguo Li, Xuefa Shi, Terry Isson, Jimin Yu, Sev Kender, Zhou Liang, George E. A. Swann, Alex Pullen, Michael E. Weber, Jinlong Du, Juan C. Larrasoaña, Jingyu Zhang, Yafang Song, F. J. González, Stefanie Kaboth-Bahr, Hai Li, Qi Zhang, Debo Zhao, Wei Cao, Mingyu Zhao, Qingsong Liu

“…Despite its relevance for understanding the climate system, the driving mechanisms underlying profound climate and carbon cycle changes – including the enigmatic Late Miocene cooling from 7 to 5.4 million years ago – remain unclear. …”
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A Multicenter Observational Prospective Cohort Study of Association of the Prehospital National Early Warning Score 2 and Hospital Triage with Early Mortality by Francisco Martín-Rodríguez, Raúl López-Izquierdo, Carlos del Pozo Vegas, Juan F. Delgado-Benito, Carmen del Pozo Pérez, Virginia Carbajosa Rodríguez, Agustín Mayo Iscar, José Luis Martín-Conty, Carlos Escudero Cuadrillero, Miguel A. Castro-Villamor

“…The Prehospital Emergency Medical Services should evaluate the implementation of the NEWS2 as a routine evaluation, which, together with the structured hospital triage system, effectively serves to predict early mortality and detect high-risk patients.…”
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Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…For this purpose a direct absorption solar collector set-up was constructed to measure evaporation rate under natural solar light, a pyranometer to measure light intensity, a K-thermocouple system to measure temperature and digital balance to measure mass loss. …”
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Ophthalmologists’ and patients’ perspectives on treatments for diabetic retinopathy and maculopathy in Vietnam: a descriptive qualitative study by Tunde Peto, Nathan Congdon, Lynne Lohfeld, Hoang Tran, Katie Curran, Van Thu Nguyen, Tung Thanh Hoang, Hue Thi Nguyen, Quan Nhu Nguyen, Catherine Dardis, Hoang Huy Tran, Anh Tuan Vu, Mai Quoc Tung

“…Recommendations by all participants included ensuring that both laser and anti-VEGF injections are widely available across the country and controlling costs for patients and the healthcare system.Conclusions Reducing DR treatment costs, optimising treatments options, and expanding the network of clinics offering treatment outside metropolitan areas were the main issues raised by participants. …”
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Gait spatiotemporal alterations in schoolchildren with overweight or obesity: a cross-sectional study by José Omar Larios-Tinoco, Xochiquetzalli Tejeda-Castellanos, Carlos Maximiliano Sánchez-Medina, Ma. Elena Ortiz-Cornejo, Horacio Márquez-González, María de Lourdes Martín-López, Salvador Villalpando-Carrión, Claudia Gutiérrez-Camacho, José Luis Alaniz-Arcos

“…Subsequently, we performed a gait study using a 3D motion analysis system and extracted the spatiotemporal parameters, and we compared the parameters obtained between the study groups. …”
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Virtual Integration of Satellite and In-situ Observation Networks (VISION) v1.0: In-Situ Observations Simulator (ISO_simulator) by M. R. Russo, M. R. Russo, S. L. Bartholomew, S. L. Bartholomew, D. Hassell, D. Hassell, A. M. Mason, E. Neininger, A. J. Perman, D. A. J. Sproson, D. Watson-Parris, D. Watson-Parris, N. L. Abraham, N. L. Abraham

“…Although this code was initially tested within the Unified Model (UM) framework, which is shared by the UK Earth System Model (UKESM), it was written as a flexible tool and it can be extended to work with other models.…”
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Restraint stress effects on glutamate signaling protein levels in the rats’ frontal cortex: Does β1 adrenoceptor activity matter? by Agnieszka Zelek-Molik, Anna Gądek-Michalska, Michał Wilczkowski, Adam Bielawski, Katarzyna Maziarz, Grzegorz Kreiner, Irena Nalepa

“…IntroductionStress-evoked dysfunctions of the frontal cortex (FC) are correlated with changes in the functioning of the glutamatergic system, and evidence demonstrates that noradrenergic transmission is an important regulator of this process. …”
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Biosynthesis, characterization, and in-vitro anticancer effect of plant-mediated silver nanoparticles using Acalypha indica Linn: In-silico approach by Luailik Madaniyah, Saidun Fiddaroini, Elok Kamilah Hayati, Moh. Farid Rahman, Akhmad Sabarudin

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Intra-articular Glenoid Fracture Managed by Arthroscopic Fixation and Open Reduction and Internal Fixation Techniques: An Analytical Study by Prahalad K Singhi, Sivakumar Raju, Chidambaram Muthu, Gopi Kumarasamy, Vinoth Thangamani, Muthukishore Marichamy

“…These patients were followed up, and functional evaluation with Constant–Murley and the University of California, Los Angeles (UCLA) scoring system were done. Results and discussion: The mean constant score at 1 and 2 years follow-up were 63.2 ± 9.3 and 78 ± 9.7, respectively. …”
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Characteristics and combustion kinetics of fuel pellets composed of waste of polyethylene terephthalate and biomass by K. Manatura, U. Samaksaman

“…CONCLUSION: These findings may provide crucial information on fuel pellets from blended polyethylene terephthalate/biomass to assist the design and operation of a co-combustion system with traditional solid fuels. Such modifications of fuel pellets suggest the possibility of operating in large-scale furnace applications and can further be upgraded to other fuels production via modern bioenergy conversion processes. ========================================================================================== COPYRIGHTS©2021 The author(s). …”
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Development of a checklist for cognitive assessment requirements (CARE) based on a Delphi consensus study by Vahid Nejati, Reza Estaji, Vicent Balanzá-Martínez, David A Balota, Suzanne Barker-Collo, Morris Bell, Jacquelyn H Berry, Khatereh Borhani, Munro Cullum, Anthony Feinstein, Charles J Golden, Raul Gonzalez, Jordan Henry Grafman, Steven D Hollon, Petra Jansen, Nicole A Kochan, Ryan Van Patten, Olivier Piguet, Sarah A Raskin, Sean B. Rourke, Andrew Scholey, Yaakov Stern, Steven Paul Woods, Michael I. Posner

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Estimated Aerosol Health and Radiative Effects of the Residential Coal Ban in the Beijing-Tianjin-Hebei Region of China by Kelsey R. Bilsback, Jill Baumgartner, Michael Cheeseman, Bonne Ford, John K. Kodros, Xiaoying Li, Emily Ramnarine, Shu Tao, Yuanxun Zhang, Ellison Carter, Jeffrey R Pierce

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Comparative genomic analysis of ten Elizabethkingia anophelis isolated from clinical patients in China by Fei Wu, Yan Wu, Miaomiao Zhang, Lijun Tian, Xue Li, Xi Luo, Yiquan Zhang, Renfei Lu

“…Based on comparative analyses, we identified a key strain, NT06, that carried a unique capsule type of X and the siderophore-mediated iron acquisition system (yclNOPQ-like genes). These findings advance our understanding of the genomic plasticity, evolution, and pathogenicity determinants of E. anophelis.…”
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Assessing the Effect of Groundnut Shell Ash-Lime Stabilization of Reclaimed Asphalt Pavement for Road Construction. by Tumusiime, Innocent

“…RAP was classified as A-1-a using the AASHTO classification system and the general rating as sub-grade in accordance with AASHTO (1986) is excellent too good. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
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