Legionella pneumophila IrsA, a novel, iron-regulated exoprotein that facilitates growth in low-iron conditions and modulates biofilm formation by Alberto E. Lopez, Joshua Mayoral, Huaixin Zheng, Nicholas P. Cianciotto

“…L. pneumophila exists in many natural and human-made water systems and can be transmitted to humans through inhalation of contaminated water droplets. …”
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Equalizer Design: HBOA-DE-trained radial basis function neural networks by Santosh Kumar Das, Satya Ranjan Pattanaik, Pradyumna Kumar Mohapatra, Saroja Kumar Rout, Abdulaziz S. Almazyad, Muhammed Basheer Jasser, Guojiang Xiong, Ali Wagdy Mohamed

“…Communication systems that rely on wireless technology require signal processing techniques to improve their channel performance. …”
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Bullatine A suppresses glioma cell growth by targeting SIRT6 by Zhi Wang, Yushuai Zhu, Can Luo, Fan Zhang, Jiannong Zhao, Chuanyi Fu

“…Gliomas are the most common primary tumors of the nervous system, which is generally treated using adjuvant chemotherapy following surgical resection. …”
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Barriers and facilitators to implementation of a home-based cardiac rehabilitation programme for patients with heart failure in the NHS: a mixed-methods study by Rod S Taylor, Paulina Daw, Samantha B van Beurden, Jet J C S Veldhuijzen van Zanten, Alexander Harrison, Sinead T J McDonagh, Patrick J Doherty, Colin J Greaves, Hasnain M Dalal, Grace E R Wood

“…Different implementation contexts (urban/rural), timing (during the COVID-19 pandemic) and factors outside the healthcare team/system (quality of the REACH-HF training) were observed to negatively or positively impact the implementation process.Conclusions The findings are highly relevant to healthcare professionals involved in planning, delivering and commissioning of cardiac rehabilitation for patients with heart failure. …”
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Comparing Virtual Reality–Based and Traditional Physical Objective Structured Clinical Examination (OSCE) Stations for Clinical Competency Assessments: Randomized Controlled Trial... by Tobias Mühling, Verena Schreiner, Marc Appel, Tobias Leutritz, Sarah König

“…Student perceptions of the VRS were collected through a quantitative and qualitative postexamination online survey, which included a 5-point Likert scale ranging from 1 (minimum) to 5 (maximum), to evaluate the acceptance and usability of the VR system. Organizational and technical feasibility as well as cost-effectiveness were also evaluated. …”
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A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study by Michael Zeiler, Nikolas Dietzel, Fabian Haug, Julian Haug, Klaus Kammerer, Rüdiger Pryss, Peter Heuschmann, Elmar Graessel, Peter L Kolominsky-Rabas, Hans-Ulrich Prokosch

“…The app’s usability was evaluated using the System Usability Scale (SUS), and verbal feedback by the end users was obtained using the think-aloud method. …”
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Heterogeneous occurrence of evergreen broad-leaved forests in East Asia: Evidence from plant fossils by Jiagang Zhao, Shufeng Li, Jian Huang, Wenna Ding, Mengxiao Wu, Tao Su, Alexander Farnsworth, Paul J. Valdes, Linlin Chen, Yaowu Xing, Zhekun Zhou

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The Relationship between Side of Onset and Cerebral Regional Homogeneity in Parkinson’s Disease: A Resting-State fMRI Study by Kai Li, Hong Zhao, Chun-Mei Li, Xin-Xin Ma, Min Chen, Shu-Hua Li, Rui Wang, Bao-Hui Lou, Hai-Bo Chen, Wen Su

“…The changed brain activity in the right temporal pole may play a compensatory role for depression and anxiety in PD, and the altered cerebral function in the right frontal motor area in RPD may represent the reorganization of the motor system in RPD.…”
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The impact of Covid-19 on harm reduction policies in Iran: an interrupted time series analysis by Siavash Beiranvand, Meysam Behzadifar, Aidin Aryankhesal, Seyed Jafar Ehsanzadeh, Masoud Behzadifar

“…Abstract Background The global emergence of the Covid-19 pandemic in 2019 posed unprecedented challenges to healthcare systems, disrupting routine services and necessitating swift adaptations. …”
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Influence of light quality on the profiling of metabolites and the status of Lactobacillus community in the phyllosphere of hydroponically grown ginseng by Nooruddin Bin Sadiq, Ji-Eun Lee, Muhammad Hamayun, Seda Nur Kabadayı, Na-Yun Park, Bokyung Lee, Ho-Youn Kim

“…Environmental factors, such as light intensity and quality, are known to influence the composition and function of phyllosphere microbiota. In hydroponic systems, these interactions are particularly relevant, as they can significantly affect plant growth and yield. …”
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Effect of Acupuncture Exercise Therapy On Isokinetic Muscle Strength and Exercise Ability of Patients after Anterior Cruciate Ligament Reconstruction by Wen YAN, Jiaying MURONG, Shuyi CUI, Wanwen HE, Xun ZHUANG

“…Before and after four courses of treatment, the range of motion of knee active joint was measured by protractor, the knee function was evaluated by Lysholm knee joint score and IKDC subjective knee score, and the peak torque (PT), average power (AP) and total work (TW) of quadriceps femoris during knee extension were collected by isokinetic muscle strength test system.Results:Before treatment, there was no significant difference in maximum flexion, Lysholm score, IKDC score, PT, AP and TW of quadriceps femoris between the two groups (<italic>P</italic>&gt;0.05). …”
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DAMPs prognostic signature predicts tumor immunotherapy, and identifies immunosuppressive mechanism of pannexin 1 channels in pancreatic ductal adenocarcinoma by Qianxue Wu, Qian Xiao, Qian Xiao, Xin Tang, Liuying Li, Daqiang Song, Yang Zhou, Benhua Li, Benhua Li, Guosheng Ren, Guosheng Ren, Fang Luo

“…Mechanically, through Bulk-RNA sequencing and experiments, we found that PANX1 promoted tumor progression and immune regulation via the ATP release to active NOD1/NFκB signaling pathway in PDAC.ConclusionOur in silico analyses established a classification system based on ICD-related DAMPs genes in PDAC, and constructed a DAMPs-related prognostic model to predict the efficacy of immunotherapy. …”
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Dairy Production in the Chuvash Republic: Success Factor Analysis by Natalya M. Suray, Alexander L. Tatochenko, Elena A. Krasil'nikova, Naila A. Teplaia, Alexey P. Mikhalev, Galina V. Zhdanova

“…However, the comprehensive system of state support measures remains the most important success factor.…”
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Analysis of geothermal impact on metabolite compounds of heat-tolerant plant species using clustering and similarity cliff by N.B. Maulydia, K. Khairan, T.E. Tallei, F. Mohd Fauzi, R. Idroes

“…Clustering analysis and similarity cliff were assessed by employing the simplified molecular input line-entry system and fragment-based fingerprint.FINDINGS: Fifteen different plant species from diverse families—Apocynaceae, Asteraceae, Euphorbiaceae, Fabaceae, Lamiaceae, Moraceae, Pteridaceae, Rhamnaceae, and Verbenaceae were found in this study. …”
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Reverse Shoulder Arthroplasty Baseplate Stability Is Affected by Bone Density and the Type and Amount of Augmentation by Daniel Ritter, Patric Raiss, Patrick J. Denard, Brian C. Werner, Manuel Kistler, Celina Lesnicar, Micheal van der Merwe, Peter E. Müller, Matthias Woiczinski, Coen A. Wijdicks, Samuel Bachmaier

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Establishment of Fermentation Kinetic Model of Streptococcus thermophilus JM108 by Wen SUN, Baolei LI, Baochao HOU, Weilian HONG, Jian HE, Chao LIANG, Yu ZHANG, Chaoxin MAN, Yujun JIANG, Ling GUO

“…The viable bacteria count, lactic acid content, and glucose content of Streptococcus thermophilus JM108 in the fermentation system were measured every 2 h. The measured values were nonlinearly fitted using the three classical models: Logistic model, Boltzmann model, and SGompertz model. …”
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Prevalence of attention deficit hyperactive disorder (ADHD) symptoms in selected government primary schools in Wakiso District, Uganda by Josephine Ssirimuzaawo, Miph Musoke, Pio Frank Kiyingi

“…By addressing this research gap, the paper adds valuable insights to the field of ADHD research, shedding light on the prevalence of ADHD symptoms, which can be used to investigate the impact of ADHD on academic performance within the Ugandan education system further. The findings of this study have the potential to inform educational policies and interventions tailored to address the needs of children with ADHD in Africa and beyond.…”
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Sessile Serrated Lesions: Searching for the True Prevalence and Risk Factors in China by Bing-Yue Yao, Li Zhang, Chuan-Xia Wu, Liang Zheng, Ben-Song Duan, Qin-Wei Xu, Jing-Jing Lian, Hai-Bin Zhang, Yu Wang, Jia Cao

“…Data were sourced through the electronic medical record system and included information such as age, sex, lesion location, number, and pathology. …”
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Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Outcomes Among Patients with Trauma in the Emergency Department: A Comparison with the Modified Early Warni... by Min Woo Kang, Seo Young Ko, Sung Wook Song, Woo Jeong Kim, Young Joon Kang, Kyeong Won Kang, Hyun Soo Park, Chang Bae Park, Jeong Ho Kang, Ji Hwan Bu, Sung Kgun Lee

“…Purpose To evaluate the severity of trauma, many scoring systems and predictive models have been presented. …”
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Fusidic Acid and Lidocaine-Loaded Electrospun Nanofibers as a Dressing for Accelerated Healing of Infected Wounds by Alsulami KA, Bakr AA, Sirwi A, Elfaky MA, Shaik RA, Alshehri BY, Aodah AH, Al Fayez N, Alshehri AA, Almughem FA, Halwani AA, Tawfik EA

“…Herein, two polymer-based nanofibrous systems were developed using poly-lactic-co-glycolic-acid (PLGA) and polyvinylpyrrolidone (PVP) loaded with a combination of an antibiotic (Fusidic acid, FA) and a local anesthetic (Lidocaine, LDC) via electrospinning technique for an expedited healing process by preventing bacterial infections while reducing the pain sensation.Results: The fabricated nanofibers showed an excellent morphology with an average fiber diameter of 556 ± 71 nm and 291 ± 87 nm for the dual drug-loaded PLGA/PVP and PVP nanofibers, respectively. …”
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