Generation of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination by Dongjin Oh, Nayoung Hong, Kiyoung Eun, Joohyeong Lee, Lian Cai, Mirae Kim, Hyerin Choi, Ali Jawad, Jaehyung Ham, Min Gi Park, Bohye Kim, Sang Chul Lee, Changjong Moon, Hyunggee Kim, Sang-Hwan Hyun

“…This melanoma-inducing system, heritably transmitted to offspring, supports large-scale studies. …”
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Radioprotective effects of polysaccharides from Poria cocos peels against 60Co-γ induced oxidative damage in vitro and in vivo by Keke Suo, Chaoqiang Zheng, Zhipeng Li, Limin Hao, Jiaqing Zhu, Changcheng Zhao, Yanling Shi, Juanjuan Yi, Jike Lu

“…Animal experiment results showed that PCPP could effectively reduce IR-induced oxidative damage of spleens and livers in mice, and alleviate the damage to the hematopoietic system. Furthermore, PCPP could greatly increase the activity of superoxide dismutase (SOD) and the content of glutathione (GSH) in serum, livers and spleens of 60Co-γ induced mice, and correspondingly reduce the accumulation of malondialdehyde (MDA), along with the prominent reduction of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum and livers in mice. …”
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Dietary rosemary oil with/without zymogen forte improves water quality, growth hormones, immune-physiological response, stress resilience, and health status of Chelon ramada grown... by Ashraf I. G. Elhetawy, Mohammed F. El Basuini, Ahmed I. A. Mansour, Shimaa A. Shahin, Amira A. Omar, Mohamed M. Zayed, Mohamed M. Abdel-Rahim

“…In addition, there were significant enhancements observed in the levels of innate immune markers, such as white blood cells, total protein, albumin, and immunoglobulin. The complement system, specifically complement 3 and complement 4, also showed considerable improvements. …”
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One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS by Shouhong Gao, Zhengbo Tao, Jingya Zhou, Zhipeng Wang, Yunlei Yun, Mingming Li, Feng Zhang, Wansheng Chen, Yejun Miao

“…The Agilent G6410A triple quadrupole liquid chromatography-mass spectrometry system was operated under the multiple reaction monitoring mode with an electrospray ionization in the positive mode. …”
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Effect of Bloodletting Therapy on Patients with Spastic Wrist Dorsiflexion Dysfunction after Stroke by LIN Wanqing, XIE Xuemin, CHEN Bin, ZHENG Xinyi

“…Before treatment and after treatment for four weeks, the modified Ashworth scale (MAS) was used to evaluate limb spasticity; passive range of motion (PROM) of wrist dorsiflexion joint was used to evaluate wrist dorsiflexion function; the simplified Fugl-Meyer assessment upper extremity scale (FMA-UE) was used to evaluate upper limb motor function; surface electromyography such as integrated electromyogram (iEMG) and root-mean-square value (RMS) were used to evaluate the functional status of the neuromuscular system on the affected side; the clinical effects of the two groups were compared.ResultsThere was no significant difference in MAS grade, PROM score, iEMG, RMS, and FMA-UE score between the two groups before treatment (<italic>P</italic>&gt;0.05). …”
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Spatial and Temporal Variations in 94-GHz Radar Backscatter From a Springtime Snowpack by William D. Harcourt, Duncan A. Robertson, David G. Macfarlane, Brice R. Rea, Mike R. James, Mark Diggins, Blair Fyffe

“…AVTIS2 is a tripod-mounted, real-aperture radar system which mechanically scans across a scene of interest to map normalized radar cross section <inline-formula><tex-math notation="LaTeX">$(\sigma ^{0})$</tex-math></inline-formula> and 3-D point clouds. …”
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Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients by Minjie Li, Yu Gao, Lin Han, Ping Wang, Jie Li, Junhua Song, Shasha Du, Yunfei Zhang, Yumin Lyu

“…Dicentric chromosomes were searched automatically using a high-throughput chromosome analysis system and were then confirmed manually. Finally, the relationships of the frequency of dicentric chromosomes (also referred to as the dic frequency) with acute skin and marrow toxicities were assessed. …”
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Preferences of Integrated Care and the Influencing Factors Among Chinese Community-Dwelling Older Adults by Liu S, Zhao J, Liu N, Qin T, Wang F

“…Siqi Liu,1,&ast; Jun Zhao,1,&ast; Nan Liu,1 Tingting Qin,2 Fang Wang3 1Center of Health System and Policy, Institute of Medical Information & Library, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, People’s Republic of China; 2Department of Science and Technology, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 3School of Health Policy and Management, Peking Union Medical College, Beijing, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Fang Wang, School of Health Policy and Management, Peking Union Medical College, No. 9 Dongdan 3rd Alley, Dongcheng District, Beijing, 100730, People’s Republic of China, Email wang.fang@imicams.ac.cnObjective: Population aging and epidemiological transition have prompted requests for integrating health and social care. …”
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In Vivo Functional Assessment of Sodium-Glucose Cotransporters (SGLTs) Using [18F]Me4FDG PET in Rats by Yohji Matsusaka, Xinyu Chen, Paula Arias-Loza, Rudolf A. Werner, Naoko Nose, Takanori Sasaki, Steven P. Rowe, Martin G. Pomper, Constantin Lapa, Takahiro Higuchi

“…We investigated healthy rats using a dedicated small animal PET system. Dynamic imaging was conducted after administration of the reference radiotracer 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG), or the SGLT-targeting agent, [18F]Me4FDG either directly into the digestive tract (for assessing intestinal absorption) or via the tail vein (for evaluating kidney excretion). …”
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A bioinformatic search for correspondence between differentially expressed genes of domestic versus wild animals and orthologous human genes altering reproductive potential by M. P. Ponomarenko, I. V. Chadaeva, P. M. Ponomarenko, A. G. Bogomolov, D. Yu. Oshchepkov, E. B. Sharypova, V. V. Suslov, A. V. Osadchuk, L. V. Osadchuk, Yu. G. Matushkin

“…Belyaev’s discovery of destabilizing selection during the domestication of animals and that this selection affects only gene expression regulation (not gene structure) and influences systems of neuroendocrine control of ontogenesis in a stressful environment. …”
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Development of single-pin, un-barbed, pole-tagging of free-swimming dolphins and sharks with satellite-linked transmitters by Michael J. Moore, Thomas M. Lanagan, Randall S. Wells, Jason Kapit, Aaron A. Barleycorn, Jason B. Allen, Robin W. Baird, Camrin D. Braun, Gregory B. Skomal, Simon R. Thorrold

“…The latter showed very short touch/response intervals and highlighted the need for several iterative revisions of the pneumatic system. This resulted in reducing the total time from triggering to tag application to ~ 20 ms. …”
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Thymus ad astra, or spaceflight-induced thymic involution by Wataru Muramatsu, Wataru Muramatsu, Maria Maryanovich, Maria Maryanovich, Maria Maryanovich, Taishin Akiyama, Taishin Akiyama, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis, George S. Karagiannis

“…Among the most vulnerable organs is the thymus, a cornerstone of immune system functionality, tasked with generating naive T cells essential for adaptive immunity. …”
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Expert-Based Narrative Review on Compression UltraSonography (CUS) for Diagnosis and Follow-Up of Deep Venous Thrombosis (DVT) by Mario D’Oria, Laura Girardi, Ahmed Amgad, Mohab Sherif, Gabriele Piffaretti, Barbara Ruaro, Cristiano Calvagna, Philip Dueppers, Sandro Lepidi, Marco Paolo Donadini

“…Deep venous thrombosis (DVT) is a pathological condition that develops when a thrombus forms within the deep venous system. Typically, it involves the lower limbs and, less frequently, the upper extremities or other unusual districts such as cerebral or splanchnic veins. …”
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Atmospheric reductive catalytic fractionation of lignocellulose integrated with one-pot catalytic conversion of carbohydrate yielding valuable lignin monomers and platform chemical... by Meng-Ying Liu, Zhe-Hui Zhang, Xue-Qi Wang, Qian Sun, Chen Zhang, Yu Li, Zhuohua Sun, Katalin Barta, Feng Peng, Tong-Qi Yuan

“…Subsequently, in a dimethyl carbonate system, the carbohydrate component underwent complete conversion in a one-pot process, yielding furfural and 5-methoxymethylfurfural as the primary products with an impressive yield of 47.7%.…”
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A Global Empirical Model of Electron Density Profile in the F Region Ionosphere Basing on COSMIC Measurements by Qiaoling Li, Libo Liu, Maosheng He, He Huang, Jiahao Zhong, Na Yang, Man‐Lian Zhang, Jinzhe Jiang, Yiding Chen, Huijun Le, Jun Cui

“…In this study, a high precision Ne profile model, named α‐Chapman Based Electron Density Profile Model (α‐Chapman‐Based‐EDP), was built by using ∼4.5 million Ne profiles from the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC‐1) radio occultations. …”
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Concentration of traffic air pollutants and influencing metrological factors in Hawassa City roadways, Ethiopia by Asmare Asrat Yirdaw, Amanuel Ejeso, Samrawit Mokie Belayneh, Lamrot Yohannes, Anmut Endalkachew Bezie, Embialle Mengistie Beyene

“…This study aimed to determine the concentration levels and spatial and temporal variations of traffic air pollutants in Hawassa and to investigate the influence of metrological parameters on the concentration of traffic air pollutants.MethodsA real-time monitoring system of Aero-Qual Series 300/500 was used to monitor pollutants, and 24 monitoring sites were included on both heavy and low-traffic volume roads. …”
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Selectively expressed RNA molecules as a versatile tool for functionalized cell targeting by Frederik Rastfeld, Marco Hoffmann, Sylvie Krüger, Patrick Bohn, Anne-Sophie Gribling-Burrer, Laura Wagner, Nils Hersch, Carina Stegmayr, Lukas Lövenich, Sven Gerlach, Daniel Köninger, Christina Hoffmann, Helene L. Walter, Dirk Wiedermann, Hajaani Manoharan, Gereon R. Fink, Rudolf Merkel, Heribert Bohlen, Redmond P. Smyth, Maria A. Rueger, Bernd Hoffmann

“…We effectively treat breast tumor cell clusters in mixed cell systems and shrink early U87 glioblastoma cell clusters in the brain of male mice without detectable side effects. …”
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Therapeutic Effect of Yijinjing Rehabilitation Training Combined with Interference Current Therapy on Patients with Knee Osteoarthritis by XU Ming, LI Ya, QIN Shuang, LU Xiaoye, AI Kun, ZHANG Hong

“…Before and after treatment, visual analogue score (VAS) was used to evaluate the severity of pain; universal goniometer was used to measure the active range of motion (AROM); timed "up and go" test (TUGT) was used to evaluate the functional walking ability; Western Ontario and McMaster University Arthritis Index (WOMAC) score was used to evaluate knee function; and Berg balance scale (BBS) and balance function test system were used to evaluate balance function (left and right swing index, center of gravity track length, track rectangular area, track peripheral area, and track length per unit area with eyes open or closed).ResultsCompared with that before treatment, TUGT, pain, stiffness and physical function scores and total score of WOMAC, left and right swing index, center of gravity track length, track rectangular area and track peripheral area with eyes open or closed in both groups after treatment decreased significantly, the proportion of low VAS score (0-2 points), the maximum AROM, the BBS score and track length per unit area with eyes open or closed increased significantly, and the differences were statistically significant (<italic>P</italic>&lt;0.05). …”
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Application of response surface methodology (RSM) for experimental optimization in biogenic silica extraction from rice husk and straw ash by Yigezu Temesgen Zewide, Temesgen Atnafu Yemata, Adane Adugna Ayalew, Hawi Jihad Kedir, Asab Alemneh Tadesse, Asmarech Yeshaneh Fekad, Alemayehu Keflu Shibesh, Fentahun Adamu Getie, Tegen Dagnew Tessema, Tessera Alemneh Wubieneh, Wondmagegn Wonago Kululo, Muluken Tilahun Mihiret

“….%) may be new materials in the Si–C–O system that may be used in construction, ceramics and silica gel that helps to absorb moisture.…”
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Peningkatan Efisiensi Waktu Seleksi Karyawan dengan Kombinasi Metode Analytical Hierarchy Process dan Simple Additive Weighting by Julianto Lemantara, I Ketut Adi Suprianta, Lidya Ananda Arsyanti, Oktavia Deyo Lago

“…Therefore, this research aims to produce a Decision Support System (DSS) that can present appropriate recommendations in selecting the best prospective employees using Analytical Hierarchy Process (AHP) and Simple Additive Weighting (SAW) methods with a faster and more efficient time. …”
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