Transcranial vibration stimulation at 40 Hz induced neural activity and promoted the coupling of global brain activity and cerebrospinal fluid flow by Linghan Kong, Wei Jin, Yue Jiang, Fuhua Yan, Jun Liu, Eric C. Leuthardt, Guang-Zhong Yang, Yuan Feng

“…Additionally, this study investigates alterations in the global blood-oxygen-level-dependent (gBOLD) signal and cerebrospinal fluid (CSF) inflow coupling, which serve as indicators of glymphatic system function. Methods: A custom-built head actuator was used to apply 40 Hz TVS to human brain. …”
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Analysis of spatial patellofemoral alignment using novel three-dimensional measurements based on weight-bearing cone-beam CT by Yurou Chen, Fan Yu, Fanzhuang Rong, Furong Lv, Fajin Lv, Jia Li

“…Eight landmarks, two lines and a coordinate system were defined on 3D bone models of knees based on weight-bearing CT and non-weight-bearing CT. …”
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Intelligent measurement of adolescent idiopathic scoliosis x-ray coronal imaging parameters based on VB-Net neural network: a retrospective analysis of 2092 cases by Jinlong Liu, Haoran Zhang, Pei Dong, Danyang Su, Zhen Bai, Yuanbo Ma, Qiuju Miao, Shenyu Yang, Shuaikun Wang, Xiaopeng Yang

“…The uAI DR scoliosis analysis system with multi-resolution VB-Net convolution network architecture was used to measure CA, CBD, CV, RSH, T1 Tilt, PT, LLD, SS, AVT, and TS parameters. …”
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The Real-World Clinical Outcomes of Heavily Pretreated HER2+ and HER2-Low Metastatic Breast Cancer Patients Treated with Trastuzumab Deruxtecan at a Single Centre by Anna-Maria Lazaratos, Matthew Dankner, Aalya Hamouda, Soumaya Labidi, Victor Cohen, Lawrence Panasci, Jennifer E. Friedmann, François Patenaude, Cristiano Ferrario, Mark Basik, April A. N. Rose, Parvaneh Fallah

“…Of these, 15 patients had classically defined HER2-positive (HER2+) breast cancer, 4 of whom had active central nervous system (CNS) metastases. A total of 23 patients had HER2-low breast cancer, 2 of whom had active CNS disease. …”
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A Submicrosecond-Response Ultrafast Microwave Ranging Method Based on Optically Generated Frequency-Modulated Pulses by Yifei Sun, Yongchao Chen, Longhuang Tang, Xing Jia, Heli Ma, Xiang Wang, Long Chen, Shenggang Liu, Tianjiong Tao, Jian Wu, Chengjun Li, Shuanyu Liu, Weilu Chen, Wei Gu, Jia Shi, Jidong Weng

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Development of Tandem Ion Mobility Spectrometry with High-voltage Fragmentation Unit at Atmospheric Pressure for Explosives Detection by Kang-yi LIU, Tian-xin XIAN, Ling-feng LI, Yun-jing ZHANG, Xing-li HE, Peng LI

“…By changing the switch status of the ion gate and fragmentation grid, this system is capable of selecting specific parent mobility ions for fragmentation under ambient pressure. …”
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Evaluation of Renal Gene Expression of Protein Kinase C (PKC) Isoforms in Diabetic and Nondiabetic Proliferative Glomerular Diseases by Salwa Ibrahim, Laila Rashed, Sawsan Fadda

“…The increased expression of the PKC β gene in LN and MPGN highlights its role in regulation of the immune system. This may represent potential therapeutic targets for prevention of progressive kidney injury in diabetic and proliferative glomerular diseases.…”
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Network pharmacology and multi-omics validation of the Jianpi-Yishen formula in the treatment of chronic kidney disease by Yuyan Li, Yueming Luo, Yilan Hu, Siting Li, Guandong Li, Wanyangchuan Zhang, Xiufen Gu, Jianting Wang, Shunmin Li, Hong Cheng

“…However, the molecular mechanisms by which JPYS targets and modulates the host immune response remain unclear.MethodsThis study utilized network pharmacology, RNA sequencing (RNA-seq), and metabolic analyses using in vivo and in vitro models to investigate the impact of the JPYS formula on inflammation and the immune system. Specifically, the study focused on macrophage polarization and metabolic changes that may slow down the progression of CKD.ResultsA total of 14,946 CKD-related targets were identified from the GeneCards and Online Mendelian Inheritance in Man (OMIM) databases through network pharmacology analyses. 227 potential targets of the JPYS formula were predicted using the TCMSP database. …”
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Relationships Among Growth, Carcass Characteristics, and <i>Myf5 Myf6</i>, <i>MyoD,</i> and <i>MyoG</i> Genes Expression Level in Saanen Male Kids with Varying Slaughter Weights by Uğur Şen, Dilek Gökçek, Ömer Faruk Yılmaz, Hüseyin Mert Yüksel, Hasan Önder, Emre Şirin, Sibel Bozkurt, Sezen Ocak Yetişgin, Ceyhun Yücel, Karlygash Omarova, Thobela Louis Tyasi

“…Twenty male kids of the Turkish Saanen breed were individually fattened for 60 days after weaning under an intensive management system. The kids were divided into two groups: low slaughter weight (L; <i>n</i> = 11; ≤29 kg) and high slaughter weight (H; <i>n</i> = 13; >29) at the end of the fattening. …”
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Can electronic monitoring with a digital smart spacer support personalised medication adherence and inhaler technique education in patients with asthma?: Protocol of the randomised... by Job F. M. van Boven, Boudewijn H.J. Dierick, Maria Achterbosch, Sandra Been-Buck, Titia Klemmeier, Susanne J. van de Hei, Paul Hagedoorn, Huib A.M. Kerstjens, Janwillem W.H. Kocks

“…At t=1, usability and satisfaction will be analysed using the System Usability Scale and interviews with patients and healthcare providers. …”
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Bisphenol A induces apoptosis and disrupts testosterone synthesis in TM3 cells via reactive oxygen species-mediated mitochondrial pathway and autophagic flux inhibition by Wenzhe Yang, Feilong Pan, Tong Zhao, Fangfang Chen, Wenqi Shao, Jinhao Wang, Shirui Wang, Zichen Zhao, Kexiang Liu, Shuchen Zhao, Lijia Zhao

“…Bisphenol A (BPA) is a common endocrine disruptor chemical that is widely used in the production of food plastic packaging, and it has been shown to potentially harm the reproductive system. However, the specific mechanism by which BPA induces apoptosis of Leydig cells (LCs) and inhibits testosterone synthesis in these cells is unclear. …”
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Study on the application of thermal-meltable recovery of CFRP strand anchors by Yize Zuo, Yize Zuo, Shanchang Xu, Shanchang Xu, Xin Fan, Weiwei Liu, Shuai Guan, Ruixin Jia, T. Tafsirojjaman

“…Conventional pressure-type anchoring systems face challenges such as difficulty in recovery, low recovery efficiency, and insufficient durability over long-term use. …”
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Expanding the concept of ID conversion in TogoID by introducing multi-semantic and label features by Shuya Ikeda, Kiyoko F. Aoki-Kinoshita, Hirokazu Chiba, Susumu Goto, Masae Hosoda, Shuichi Kawashima, Jin-Dong Kim, Yuki Moriya, Tazro Ohta, Hiromasa Ono, Terue Takatsuki, Yasunori Yamamoto, Toshiaki Katayama

“…With its ability to obtain IDs related in different semantic relationships, a user-friendly web interface, and a regular automatic data update system, TogoID has been a valuable tool for bioinformatics. …”
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Urban and rural residence: their influence on food group consumption in Iran by Susan Darroudi, Sara Saffar Soflaei, Farzam Kamrani, Zahra Khorasanchi, Zahra Abdollahi, Nasrin Talkhi, Maryam Allahyari, Seyyed Reza Sobhani, Maryam Mohammadi-Bajgiran, Amirmohammad Naderkhmseh, Maliheh Aghasizadeh, Habibollah Esmaily, Gordon Ferns, Majid Ghayour-Mobarhan

“…Methods This study utilized data from Iran’s Food and Nutrition Surveillance System (FNS). A total of 1697 participants were randomly recruited from different rural (N = 568), urban (N = 568), and suburban (N = 561) regions across Iran. …”
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Rapid diagnostic testing combined with an immediate infectious disease consultation increases the rate of septic intensive care unit patients on targeted antibiotic therapy by Evelyn Kramme, Nadja Käding, Nadja Käding, Tobias Graf, Karolin Schmoll, Heidi Linnen, Katharina Nagel, Esther Grote-Levi, Susanne Hauswaldt, Dennis Nurjadi, Dennis Nurjadi, Jan Rupp, Jan Rupp, Jan Rupp

“…Overall adherence to the local antibiotic therapy guideline for sepsis was significantly lower in the control than in the intervention group (27.8% versus 89.3%, p&lt;0.001).ConclusionIntegration of an RDT system in the microbiological workflow for septic patients in ICU combined with a standardized ID intervention led to a significantly higher percentage of adequate antimicrobial treatment and greater adherence to local antibiotic therapy recommendations, even in a setting where 24/7 service is not available.…”
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Detection of atrial fibrillation in primary care with radial pulse palpation, electronic blood pressure measurement and handheld single-lead electrocardiography: a diagnostic accur... by Wim A M Lucassen, Henk C P M van Weert, Bjorn Winkens, Henri E J H Stoffers, J André Knottnerus, Steven B Uittenbogaart, Nicole Verbiest-van Gurp, Petra M G Erkens

“…We present pooled diagnostic parameters.Setting 47 general practices participated between September 2015 and August 2018.Participants In the electronic medical record system of the participating general practices (n=47), we randomly marked 200 patients of ≥65 years without AF. …”
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Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma by Guiyu Kang, Hui Song, Lei Bo, Qi Liu, Qiang Li, Jingtan Li, Pan Pan, Jingting Wang, Yanfei Jia, Haiji Sun, Xiaoli Ma

“…Through diverse bioinformatics analyses and immunohistochemistry, the expressions of α5-nAChR and SOX2 as well as their relations were dissected. α5-nAChR regulated the differentiation of monocytes into M2 macrophages by targeting the STAT3/SOX2/CSF-1 signaling in the coculture system by western blotting and ChIP. α5-nAChR-mediated macrophage-mediated LUAD cell migration via SOX2/CSF-1 signaling in the cocultured medium. …”
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The potential endocrine-disrupting of fluorinated pesticides and molecular mechanism of EDPs in cell models by Yalan Liu, Fengzhong Wang, Lin Li, Bei Fan, Zhiqiang Kong, Jianxin Tan, Minmin Li

“…Environmental endocrine disruptors constitute a category of exogenous compounds that interfere with the endocrine system's functions in organisms or cells. As a class of particularly representative endocrine-disrupting chemicals, the accumulation of per- and polyfluoroalkyl substances potentially leads to adverse health effects, including hormonal disruptions, developmental issues, and cancer. …”
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Inhibition of anti-tumour reactivity of immune cells in the salivary gland cancer: A proteomic approach by Rajdeep Chakraborty, Charbel Darido, Aidan Tay, Thiri Zaw, Shoba Ranganathan, Fei Liu, Giuseppe Palmisano

“…Therefore, we hypothesised that salivary gland cancer cells produce a higher number of immunosuppressive proteins that cause suppression of the immune system's anti-tumour reactivity. Method: To determine differential protein expressions in OSCC, MEC, and ACC, we constructed cancer–immune cell co-culture models using different oral and salivary gland cancer cells. …”
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The role of the Global Observatory in addressing Gender Based Violence in Sport+ by Hayley Truskewycz, Lombe Mwambwa

“…Gender equality, sport and the United Nation’s system: A historical overview of the slow pace of progress. …”
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