Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi... by Mutasim E. Ibrahim, Mohammed Abbas, Abdullah M. Al-Shahrai, Bahaeldin K. Elamin

“…Isolates were identified by the Phoenix identification system. Antimicrobial susceptibility was tested by the Kirby–Bauer disk procedure. …”
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Case Report of Jingyun Platform's Cognitive Training on Cognitive Impairment with Aphasia by Yu ZHOU, Zhuoming CHEN, Hantian GUAN, Chaoping OUYANG

“…Compared with traditional cognitive training, Jingyun platform is move effective in improving the cognition with its precise training system, and has certain advantages in response, attention, memory and in the directional improvement.…”
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Biaxial fatigue behavior of a powder metallurgical TRIP steel by S. Ackermann, T. Lippmann, D. Kulawinski, S. Henkel, H. Biermann

“…Different types of major cracks were observed on the sample surfaces after biaxial cyclic deformation by using electron monitoring in an electron beam universal system and scanning electron microscopy (SEM). Specimens with strain ratios of 1, 0.5, -0.1 and -0.5 showed mode I major cracks (perpendicular to the axis of maximum principal strain). …”
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Study on the Electromigration Organization and Mechanical Properties of Sn2.5Ag0.7Cu0.1RE/Cu Solder Joints by Yuming Wang, Keke Zhang, Chao Zhang, Fupeng Huo, Yijie Gao

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Three-dimensional linkage analysis with digital PCR for genome integrity and identity of recombinant adeno-associated virus by Tam Duong, Michele Firmo, Chien-Ting Li, Bingnan Gu, Peng Wang

“…Importantly, due to the random partitioning property of a digital PCR system, the 3D linkage analysis of rAAV viral genome requires a proper mathematical model to identify the true linked DNA molecules (full-length/intact DNA) from the population of false/unlinked DNA molecules (fragmented/partial DNA). …”
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Advances, challenges and future applications of liver organoids in experimental regenerative medicine by Da Gong, Jiaye Mo, Jiaye Mo, Mei Zhai, Fulin Zhou, Guocai Wang, Shaohua Ma, Xiaoyong Dai, Xiaoyong Dai, Xuesong Deng

“…Liver organoid technology represents a novel in vitro culture system. After several years of refinement, human liver organoids can now accurately replicate the liver’s morphological structure, nutrient and drug metabolism, gene expression, and secretory functions, providing a robust model for liver disease research. …”
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Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination by Yue Zhang, Xia Lei, Hongdan Xu, Guoliang Liu, Yeqiu Wang, Huifeng Sun, Fang Geng, Ning Zhang

“…Compared with the 8-month-old rats, a higher concentration of naringin was found in the ovaries of the 18-month-old rats; this result indicated that it may regulate the autonomic nervous dysfunction of the cerebrospinal system through the hypothalamus-pituitary-ovary axis, thus playing an anti-AD role, but further research is needed. …”
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Asthma and obesity increase inflammatory markers in children by Harshita Shailesh, Safa Noor, Lena Hayati, Antonisamy Belavendra, Nicholas Van Panhuys, Abdul Badi Abou-Samra, Stefan Worgall, Ibrahim Janahi, Ibrahim Janahi

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Effectiveness of nicotine salt vapes, cytisine, and a combination of these products, for smoking cessation in New Zealand: protocol for a three-arm, pragmatic, community-based rand... by Natalie Walker, Amanda Calder, Joanne Barnes, George Laking, Varsha Parag, Chris Bullen

“…Participants will be randomised (3:3:2 ratio) to 12 weeks of: 1) e-cigarettes (closed pod system, 3% nicotine salt, tobacco flavour) plus cytisine; 2) e-cigarettes alone, or 3) cytisine alone. …”
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Pathogenicity and Whole Genome Sequence Analysis of a Pseudorabies Virus Strain FJ-2012 Isolated from Fujian, Southern China by Xue-min Wu, Qiu-yong Chen, Ru-jing Chen, Yong-liang Che, Long-bai Wang, Chen-yan Wang, Shan Yan, Yu-tao Liu, Jin-sheng Xiu, Lun-jiang Zhou

“…FJ-2012-infected piglets developed symptoms like high body temperature and central nervous system disorders and had high mortality rate. In addition, we identified typical micropathological changes such as multiple gross lesions in infected piglets through pathological analysis and conclude that the FJ-2012 genome is significantly different from known pseudorabies viruses, in which insertions, deletions, and substitutions are observed in multiple immune and virulence genes. …”
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Rapid growing mass of the mandible due to an oral metastasis of thymoma: Case report of an extremely rare localization and review of published cases by Francesco Scilla, Cosimo Rupe, Gioele Gioco, Luca Raffaelli, Filippo Lococo, Ciro Mazzarella, Guido Rindi, Romeo Patini, Carlo Lajolo

“…Thymomas and thymic carcinomas are the two main tumors that can affect the thymus, a lymphatic gland that plays an important role in regulating the immune system. The aims of this paper are (i) to describe an extremely rare case of thymoma metastasis to the oral cavity (ii) report all published cases of thymic tumor metastases to the oral cavity. …”
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First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies by Peter Ellmark, Jeffrey Yachnin, Ana Carneiro, Lena Schultz, Amanda Hahn, Sumeet Ambarkhane, Karin Enell Smith, Gustav J. Ullenhag

“…Exploratory objectives included pharmacodynamic (PD) assessment of immune system biomarkers.Results Of the 27 patients screened, 25 received treatment with ATOR-1017. …”
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Master Robotic Net by Vladimir Lipunov, Victor Kornilov, Evgeny Gorbovskoy, Nikolaj Shatskij, Dmitry Kuvshinov, Nataly Tyurina, Alexander Belinski, Alexander Krylov, Pavel Balanutsa, Vadim Chazov, Artem Kuznetsov, Petr Kortunov, Anatoly Sankovich, Andrey Tlatov, A. Parkhomenko, Vadim Krushinsky, Ivan Zalozhnyh, A. Popov, Taisia Kopytova, Kirill Ivanov, Sergey Yazev, Vladimir Yurkov

“…Such a survey will make it possible to address a number of fundamental problems: search for dark energy via the discovery and photometry of supernovae (including SNIa), search for exoplanets, microlensing effects, discovery of minor bodies in the Solar System, and space-junk monitoring. All MASTER telescopes can be guided by alerts, and we plan to observe prompt optical emission from gamma-ray bursts synchronously in several filters and in several polarization planes.…”
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Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish by Wang Lin, Ling Liao, Ling Ling, Huimin Luo, Ying Jiang, Xinru Li, Yilong Yao, Pinhong Yang

“…However, the joint effects of microcystin-LR (MCLR) in combination with polystyrene microplastics (PSMPs) on the thyroid endocrine system of adult fish remains unclear. In our study, male zebrafish (Danio rerio) were exposed to environmentally relevant concentrations of MCLR alone (0, 0.8, 4, 20 μg/L) and a mix of MCLR and PSMPs (100 μg/L) for 60 days. …”
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Genomic insights into multidrug-resistant Acinetobacter baumannii strains isolated from Dhaka, Bangladesh by Sadia Ferdous, K M Shayerul Abedin Shayer, Afia Anjum, Sabbir R. Shuvo, Ishrat Jabeen, Kristi Paul Hridi, A.K.M. Imrul Hassan, Md Imran Khan, Mohammad Fazle Alam Rabbi, Mahmud Hossain, Kazi Nadim Hasan, Sohidul Islam

“…Multidrug-resistant (MDR) A. baumannii is a growing concern to the healthcare system in Bangladesh, necessitating the elucidation of the genetic characteristics of this species. …”
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Presenting the Model of Eco-Leadership in Elementary Schools with an Interpretive Phenomenological Approach by Adel Zahed babolan, Seyyedmohammad Seyyedkalan

“…Many principals and teachers argue that talking about ecological educational and training activities and observing the environmental conditions of schools is still the missing link in the educational system, which is impossible without valid reflections and criticisms of the school environment. …”
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Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy by D. A. Rozenko, A. I. Shikhlyarova, L. N. Vaschenko, N. N. Popova, Yu. Yu. Arapova, A. Yu. Ardzha, A. A. Korobov

“…The functional state of the central nervous system in all patients was assessed by the parameters of the electroencephalography (EEG) bioelectrical activity. …”
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Unlocking the potential for optic nerve regeneration over long distances: a multi-therapeutic intervention by Zhen-Gang Liu, Zhen-Gang Liu, Lai-Yang Zhou, Lai-Yang Zhou, Lai-Yang Zhou, Lai-Yang Zhou, Yong-Quan Sun, Yong-Quan Sun, Yong-Quan Sun, Yong-Quan Sun, Yi-Hang Ma, Chang-Mei Liu, Chang-Mei Liu, Chang-Mei Liu, Chang-Mei Liu, Bo-Yin Zhang

“…These strategies are crucial not only for optic nerve regeneration but also for broader applications in central nervous system repair. In this review, we discuss multifactors therapeutic strategies for optic nerve regeneration, offering insights into advancing nerve regeneration research.…”
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From Pioneering Discoveries to Innovative Therapies: A Journey Through the History and Advancements of Nanoparticles in Breast Cancer Treatment by Basingab FS, Alshahrani OA, Alansari IH, Almarghalani NA, Alshelali NH, Alsaiary AH, Alharbi N, Zaher KA

“…This article also discusses the latest advancements in nanoparticle research, including drug delivery systems and combination therapy innovations, while addressing the current technical, biological, and regulatory challenges. …”
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Valorization of mixed blackwater/agricultural wastes for bioelectricity and biohydrogen production: A microbial treatment pathway by G. Plason Z. Plakar, Abdulsalami S. Kovo, Kanayo L. Oguzie, Emeka E. Oguzie

“…This study underscores the potential for generating bioelectricity and biohydrogen from the microbial treatment of mixed blackwater and agricultural wastes in a single system, eliminating the need for separate treatment and the use of external energy source. …”
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