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53461
Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol
Published 2025-01-01“…Deoxynivalenol (DON), a prevalent mycotoxin produced by Fusarium species, contaminates global agricultural products and poses significant health risks, particularly to the gastrointestinal (GI) system. DON exposure disrupts ribosomal function, inducing stress responses linked to various inflammatory diseases, including inflammatory bowel disease (IBD). …”
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53462
Diagnostic Accuracy of Mammography, Ultrasound, and Fine-Needle Aspiration in Detecting Breast Cancer in Patients with Painful Breast Masses:A Medical Record-Base Study
Published 2025-01-01“…Based on the grading system, 59 participants had grade II tumors, six had grade I tumors, and one had a grade III tumor. …”
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53463
Bridging the Gap Between Machine Learning and Medicine: A Critical Evaluation of the Dworak Regression Grade in Rectal Cancer
Published 2024-01-01“…We examined the impact of grading system subjectivity on the algorithm. Analyzing clinical parameters and medical notes from 85 rectal cancer patients, we identified patients with ambivalent grades, the “gray-zone patients,” and explored the algorithm’s difficulty in predicting their regression grade. …”
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53464
Utilization of a Joint Point Regression Model for Predicting Mortality Rates of Common Cancers in Babol City
Published 2025-01-01“…Methods This cross‐sectional study considered all registered cancer‐related deaths from 2013 to 2021 in the Babol University of Medical Sciences' death registration and classification system. Crude and age‐standardized rates and cancer trends were calculated and predicted for the next 5 years, overall and by type of cancer and gender. …”
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53465
A Digital-based Talent Acquisition Framework for Start-ups: A Qualitative Multiple Case Study
Published 2024-06-01“…Implementing an agile selection system using technology is recommended for talent selection while updating onboarding processes for agility is vital in the onboarding phase. …”
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53466
A bioprocess engineering approach for the production of hydrocarbons and fatty acids from green microalga under high cobalt concentration as the feedstock of high-grade biofuels
Published 2024-05-01“…However, cultivating and scaling up B. braunii using conventional aqua-suspended cultivation systems remains a challenge. In this study, we optimized medium components and light intensity to enhance lipid and hydrocarbon production in a multi-cultivator airlift photobioreactor. …”
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53467
Femtomolar hydrogen sulfide detection via hybrid small-molecule nano-arrays
Published 2024-12-01“…Among these, hydrogen sulfide (H2S) has emerged as a critical player in cardiovascular and nervous system signaling. On-chip immunoassays, particularly nanoarray-based interfacial detection, offer promising avenues for ultra-sensitive analysis due to their confined reaction volumes and precise signal localization. …”
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53468
Inflammatory Response in Preterm and Very Preterm Newborns with Sepsis
Published 2016-01-01“…The response of the adaptive immune system is usually less intense in premature neonates than term neonates. …”
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53469
Lipid Nanoparticles With Fine‐Tuned Composition Show Enhanced Colon Targeting as a Platform for mRNA Therapeutics
Published 2025-01-01“…Using interleukin‐10‐encoding mRNA as therapeutic cargo, n‐LNPs demonstrated a reduction of pathological burden in colitis‐bearing mice. n‐LNPs represent a starting point to further investigate the influence of LNPs composition on systemic biodistribution, ultimately opening new therapeutic modalities in different pathologies.…”
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53470
SFMHANet: Surface Fitting Constrained Multidimensional Hybrid Attention Network for Aero-Optics Thermal Radiation Effect Correction
Published 2025-01-01“…When an aircraft is flying at hypervelocity in the atmosphere, the airflow and the optical cowl rub against each other, and the airflow's kinetic energy in the boundary layer is transformed into thermal energy, which causes the cowl's surface temperature to rise nonuniformly and produces thermal radiation interference with the imaging system of the detector. In practical application scenarios, the aero-optical thermal radiation patterns in degraded images are not fixed, and types of aero-optics thermal radiation are more variable and complex. …”
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53471
Psychological and pedagogical readiness of a guide to work with disabled people
Published 2020-01-01“…The conclusion was reached that the methods of education in higher education institutions and the system of advanced training for specialists-guides need to be further developed and improved in order to maximise the implementation of pedagogical function of culture-oriented sightseeing tourism. …”
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53472
The safety of cyclosporine and tacrolimus in pediatric nephrotic syndrome patients: a disproportionate analysis based on the FAERS database
Published 2025-01-01“…ObjectiveThis study aimed to systematically evaluate the safety of cyclosporine (CsA) and tacrolimus (TAC) in pediatric nephrotic syndrome (NS) patients using real-world data from the FDA Adverse Event Reporting System (FAERS).MethodsWe analyzed adverse event (AE) reports from the FAERS database between Q4 2003 and Q2 2024, focusing on AEs associated with CsA and TAC in NS patients aged 18 years and younger. …”
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53473
A headspace-gas chromatography method for isopropanol determination in warfarin sodium products as a measure of drug crystallinity
Published 2018-03-01“…A headspace-gas chromatography (HS-GC) method was developed and validated for IPA determination in the WS drug product. n-propanol (NPA) was used as internal standard and the method was validated for specificity, system suitability, linearity, accuracy, precision, range, limits of detection and quantification, and robustness. …”
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53474
Immunogenic properties of nickel-doped maghemite nanoparticles and the implication for cancer immunotherapy
Published 2024-12-01“…They are also increasingly being implemented in cancer immunotherapy because of their ability to deliver drugs and modulate the immune system. However, the effect of nanoparticles on immune cells involved in the anti-tumor immune response is not well understood. …”
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53475
Alterations in the social-conditioned place preference and density of dopaminergic neurons in the ventral tegmental area in Clsnt2-KO mice
Published 2023-04-01“…This study aims to evaluate the social-conditioned place preference as well as density of dopaminergic (DA) neurons in the ventral tegmental area (VTA), which belongs to the brain reward system, in the males of the Clstn2-KO strain using wild type C57BL/6J males as controls. …”
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53476
Magnetic Targeted Delivery of Induced Pluripotent Stem Cells Promotes Articular Cartilage Repair
Published 2017-01-01“…The histologic grading score was significantly better in the treatment group compared to the control group. m-iPS cells maintained pluripotency, and the magnetic delivery system proved useful and safe for cartilage repair using iPS cells.…”
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53477
Scalable information extraction from free text electronic health records using large language models
Published 2025-01-01“…Methods We conducted a cross-sectional study using EHR data from the Mass General Brigham (MGB) system, analyzing free-text notes for SDoH information. …”
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53478
Economic impact of potentially inappropriate prescribing and related adverse events in older people: a cost-utility analysis using Markov models
Published 2019-01-01“…We developed Markov models incorporating the AEs of each PIP, populated with published estimates of probabilities, health system costs (in 2014 euro) and utilities.Participants A hypothetical cohort of 65 year olds analysed over 35 1-year cycles with discounting at 5% per year.Outcome measures Incremental cost, quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios with 95% credible intervals (CIs, generated in probabilistic sensitivity analysis) between each PIP and an appropriate alternative strategy. …”
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53479
Triboelectric tactile sensor for pressure and temperature sensing in high-temperature applications
Published 2025-01-01“…The proposed self-powered multimodal sensing system offers a wider range of possibilities for human/robot/environment interaction applications.…”
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53480
STABILITY OF DEVELOPMENT OF FUTURE PROFESSIONALS’ EMOTIONAL INTELLIGENCE
Published 2018-09-01“…In this regard, the problem of emotional competency formation of future experts is becoming topical in the system of vocational training.The aim of this paper is to generalize the results of the study on the sustainable development of student emotional intelligence by means of active forms of education (training sessions and workshops).Methodology and research methods. …”
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