Clinical Evaluation of Faricimab in Real-World Diabetic Macular Edema in India- A Multicenter Observational Study by Chakraborty D, Das S, Maiti A, Sinha TK, Das A, Sheth J, Boral SK, Mondal S, Nandi K

“…Significant reductions in HRF were also observed across both inner (P< 0.001) and outer retinal layers (P< 0.001). No ocular or systemic adverse events were reported.Conclusion: Faricimab treatment resulted in significant improvements in visual acuity and anatomical outcomes in both treatment-naïve and recalcitrant DME eyes, highlighting its potential as a valuable therapeutic option in diverse clinical settings. …”
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Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection by Trever T. Greene, Yeara Jo, Carolina Chiale, Monica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L. Codrington, Katelynn R. Kazane, Elizabeth Akbulut, Shobha Swaminathan, Yu Fujita, Patricia Fitzgerald-Bocarsly, Thekla Cordes, Christian Metallo, David A. Scott, Elina I. Zúñiga

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Factors accounting for limited sexual reproduction in a long-lived unisexual plant species by Irene Bisang, Flavien Collart, Flavien Collart, Alain Vanderpoorten, Lars Hedenäs

“…IntroductionPlant dispersal directly depends on reproduction success, and hence, on sexual systems. In bryophytes, wherein fertilization involves a continuous film of water between male and female sexual organs, reproduction in unisexual species involves the sympatric distribution of male and female sex-expressing individuals. …”
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Why do acute healthcare staff engage in unprofessional behaviours towards each other and how can these behaviours be reduced? A realist review protocol by Ruth Abrams, Aled Jones, Johanna Westbrook, Jill Maben, Russell Mannion, Judy M Wright, Mark Pearson, Justin Avery Aunger

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Diagnostic Phase of Calcium Scoring Scan Applied as the Center of Acquisition Window of Coronary Computed Tomography Angiography Improves Image Quality in Minimal Acquisition Windo... by Eriko Maeda, Kodai Yamamoto, Shigeaki Kanno, Kenji Ino, Nobuo Tomizawa, Masaaki Akahane, Rumiko Torigoe, Kuni Ohtomo

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Changing Our Mental and Emotional Trajectory (COMET): The Feasibility and Acceptability of a Rural Community-Based Strategy to Prevent Mental and Emotional Health Problems by Linda Zittleman, Maret Felzien, Kristen Curcija, Christopher Bennett, Kaitlyn Bennett, Joseph Carrica, Christin Sutter, Ashley Sherrill, John M Westfall

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The WF1 (White Flower 1) gene controlling the white color of petals and flowering time in lines from a mapping population of flax (Linum usitatissimum L.) by N. B. Brutch, I. I. Matvienko, E. A. Porokhovinova, A. V. Pavlov

“…The analysis of segregation in F2 held under  the long (19 hours) and short (12 hours, daylength at the equator) day conditions showed that  the number of leaves on the plant stem was associated with the flowering time and controlled by close genetic systems only under the long-day conditions. In addition, no relationship between the flowering time and petal color was found under  the short-day  conditions. …”
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Effects of Soil Conservation Practice and Crop Rotation on Selected Soil Physicochemical Properties: The Case of Dembecha District, Northwestern Ethiopia by Melkamu Degu, Asmare Melese, Wondwosen Tena

“…Crop rotation systems especially dominated by cereals (maize and wheat) are intimately linked to soil properties. …”
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Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients by Mohamed Abdel-Raoof Fouda, Mohamed Abdel-Wahhab, Ahmed Esmail Abdelkader, Mohsen El-Sayd Ibrahim, Taher Abozeid Elsheikh, Hisham Mohammad Aldeweik, Nora Elfeky

“…Abstract Background Liver transplantation (LT) is a critical intervention for individuals with end-stage liver disease; yet, post-transplant problems, especially infections, graft rejection, and chronic liver disease, are often linked to systemic inflammation. Cytokines, small signaling molecules, significantly influence immune responses during and post-liver transplantation. …”
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Early antiretroviral therapy in SIV-infected rhesus macaques reveals a multiphasic, saturable dynamic accumulation of the rebound competent viral reservoir. by Brandon F Keele, Afam A Okoye, Christine M Fennessey, Benjamin Varco-Merth, Taina T Immonen, Emek Kose, Andrew Conchas, Mykola Pinkevych, Leslie Lipkey, Laura Newman, Agatha Macairan, Marjorie Bosche, William J Bosche, Brian Berkemeier, Randy Fast, Mike Hull, Kelli Oswald, Rebecca Shoemaker, Lorna Silipino, Robert J Gorelick, Derick Duell, Alejandra Marenco, William Brantley, Jeremy Smedley, Michael Axthelm, Miles P Davenport, Jeffrey D Lifson, Louis J Picker

“…The rebound competent viral reservoir (RCVR)-virus that persists during antiretroviral treatment (ART) and can reignite systemic infection when treatment is stopped-is the primary barrier to eradicating HIV. …”
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Assessment of Patient’s Satisfaction and Associated Factors regarding Postoperative Pain Management at the University of Gondar Compressive Specialized Hospital, Northwest Ethiopia... by Yosef Belay Bizuneh, Girmay Fitiwi Lema, Demeke Yilkal Fentie, Yophtahe Woldegerima Berhe, Henos Enyew Ashagrie

“…ASA1 (AOR = 3.55: 95% CI = 1.20–10.55) and ASA2 patients (AOR = 3.72: 95% CI = 1.04–13.28), absence of postoperative pain (AOR = 1.86: 95% CI = 1.02–3.39), peripheral nerve block done (AOR = 9.14: 95% CI = 3.93 20.86), received analgesic before request (AOR = 6.90: 95% CI = 3.72–12.83), and received systemic analgesics (AOR = 6.10: 95% CI = 1.17–33.91) were significantly associated with the level of satisfaction. …”
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Impact of social isolation during the COVID-19 pandemic on the mental health of university students and recommendations for the post-pandemic period: A systematic review by Tamiris Beppler Martins, Joaquim Henrique Lorenzetti Branco, Taís Beppler Martins, Gilmar Moraes Santos, Alexandro Andrade

“…Additionally, universities should implement proactive support systems to cultivate a safe and inclusive environment for students.…”
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Human health risk assessment of aluminium in water treated with aluminium-based coagulants in a rural area by Fernando García-Ávila, Tatiana Encalada-Alvear, Luis M. Alvarez-Altamirano, Alex Avilés-Añazco, Lorgio Valdiviezo-Gonzalez, Emigdio Alfaro-Paredes

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Atomic Force Microscopy (AFM) nanomechanical characterization of micro- and nanoplastics to support environmental investigations in groundwater by Massimiliano Galluzzi, Michele Lancia, Chunmiao Zheng, Viviana Re, Valter Castelvetro, Shifeng Guo, Stefano Viaroli

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Dataset of shotgun metagenomic evaluation of Sorghum bicolor rhizosphere microbiome in soils preceded by Glycine maxNCBINCBINCBINCBI by Olubukola Oluranti Babalola, Ben Jesuorsemwen Enagbonma

“…Actinomycetota and Function unknown dominated the microbiomes across all cropping systems. The insights gained from this dataset hold promise for advancing sustainable agricultural practices, particularly through optimizing crop rotations, developing microbial bioinoculants, and enhancing soil health. …”
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The effect of blood glucose levels on serum triglyceride clearance in patients with hyperlipidemic acute pancreatitis by Yuxin Liu, Shuqi Qin, Si Dai, Jing Zhou, Zhendan Wang, Guojian Yin

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Pivotal roles of Plasmodium falciparum lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalization by Junpei Fukumoto, Minako Yoshida, Suzumi M. Tokuoka, Eri Saki H. Hayakawa, Shinya Miyazaki, Takaya Sakura, Daniel Ken Inaoka, Kiyoshi Kita, Jiro Usukura, Hideo Shindou, Fuyuki Tokumasu

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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…We now examined for the first time how LD-RT influences FLS and bone marrow-derived macrophages in co-culture systems of an experimental model of RA to reveal further mechanisms of immune modulatory effects of low and intermediate dose of ionizing radiation. …”
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Practice on Metered Dose Inhaler Techniques and Its Associated Factors among Asthmatic Patients at Debre Markos Comprehensive Specialized Hospital, East Gojjam, Ethiopia: A Prospec... by Tadele Asmare, Anteneh Belayneh, Bekalu Dessie

“…A metered-dose inhaler remains the principal route for drug administration, and it has greater advantages over systemic treatment. In routine use, however, a majority of patients make inhalation errors. …”
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Microbial Contamination and Food Safety Aspects of Cassava Roasted Flour (“Rale”) in Mozambique by Andreia Massamby, Su-lin L. Leong, Bettina Müller, Lucas Tivana, Volkmar Passoth, Custódia Macuamule, Mats Sandgren

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