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52521
Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro...
Published 2025-03-01“…Conclusions: Community-onset BSIs demonstrated substantial prevalence of resistant pathogens, including ESBL and MRSA, emphasizing the need for robust surveillance systems. Age is a critical factor in guiding empirical antibiotic therapy in the ED.…”
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52522
Methanotroph-methylotroph lipid adaptations to changing environmental conditions
Published 2025-02-01“…Assessing the interaction and physiological status of these two microbial groups is essential for determining the microbial methane buffering capacity of environmental systems. Microbial membrane lipids are commonly used as taxonomic markers of specific microbial groups; however, few studies have characterized the changes of membrane lipids under different environmental conditions. …”
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52523
Periodontitis promotes tumor growth and immune evasion via PD-1/PD-L1
Published 2024-11-01“…Abstract Background Our study investigated the role of experimental periodontitis on tumor growth, local and systemic immunosuppressive status, and programmed death receptor 1 (PD-1) / programmed death ligand 1 (PD-L1) expression in oral squamous cell carcinoma (OSCC) and prostate cancer. …”
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52524
Laser powder bed fusion of Ti6Al4V using low-cost high efficiency 450 nm diode point melting
Published 2025-01-01“…It uses high power fibre lasers directed by a galvanometric scanner to rapidly melt powdered feedstock. LPBF systems are expensive, making them inaccessible to many sectors and have challenges related to in-process thermal control, production of large components and scalability limitations. …”
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52525
Evaluation of the Management of Patients with Detectable Viral Load after the Implementation of Routine Viral Load Monitoring in an Urban HIV Clinic in Uganda
Published 2019-01-01“…Despite the implementation of internal systems to manage patients failing ART, we found substantial leakages in the monitoring “cascade”. …”
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52526
Current Trends in Mortality Attributable to Racial or Ethnic Disparities in Post-Surgical Population in The United States: A Population-Based Study
Published 2023-12-01“…Our data provides a framework for incorporating population and health systems measures for eliminating disparity in surgical mortality within the next decade.…”
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52527
Climate change and the sustainable use of medicinal plants: a call for “new” research strategies
Published 2025-02-01“…Despite these growing challenges, there is limited knowledge of potential strategies to prevent or mitigate these impacts, particularly for vulnerable species collected from the wild or harvested from traditional production systems. Hence, effective strategies for preserving and increasing plant populations are urgently needed. …”
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52528
Impact of commercial gut health interventions on caecal metagenome and broiler performance
Published 2025-01-01“…GHI supplementation generally affected the abundance of microbial enzymes relating to carbohydrate and protein digestion and metabolic pathways relating to energy, nucleotide synthesis, short-chain fatty acid synthesis, and drug-transport systems. These shifts are hypothesised to differentiate performance among groups and cycles, highlighting the beneficial role of several bacteria, including Rikenella microfusus and UBA7160 species. …”
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52529
Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey
Published 2024-05-01“…We discuss why signals of prey and predator population dynamics decoupling are less likely to be observed in systems with a high diversity of prey, such as African savannas, and why inputs of mega-carcasses as pulsed resources hardly impacted top-down relationships in the long run. …”
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52530
Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury
Published 2025-02-01“…To address this, we conducted bioinformatics and systems biology analyses to identify molecular biomarkers and pathways that link SCI to chronic pain. …”
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52531
Body composition as an indicator of metabolic changes in mice obtained by <i>in vitro</i> fertilization
Published 2023-07-01“…To identify body systems subject to epigenetic transformation during in vitro fertilization (IVF), comparative morphological and functional studies were performed on sexually mature offspring of outbred CD1 mice, specific-pathogen-free (SPF), obtained by IVF (experiment) and natural conception (control). …”
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52532
Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments
Published 2025-01-01“…The study demonstrates that FLI is a powerful analytical tool to monitor the delivery of antibodydrugs both in cell cultures and in vivo live systems. Especially, MFLI FRET is a unique imaging modality that can directly quantify target engagement with the potential to elucidate the role of the TME in drug delivery efficacy in intact live tumor xenografts.…”
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52533
Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study
Published 2020-01-01“…These findings support that there are systemic metabolic disruptions that are detectable in early pregnancy (8-14 weeks of gestation) among pregnant African American women who develop PE and gHTN. …”
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52534
Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review
Published 2025-02-01“…The coupling of phytotherapy with novel drug delivery systems such as nanoparticles, liposomes, nanotubes, quantum dots, etc. can help translate these beneficial effects of phytochemicals into clinical practice. …”
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52535
The impact of food-based incentive behaviors on oral health among Saudi children: a cross-sectional study
Published 2025-02-01“…These findings highlight the need for targeted educational and intervention strategies that address cultural practices and promote healthier reward systems. By reducing sugary food rewards and encouraging non-food-based incentives, improvements in children’s oral health can be achieved.…”
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52536
Energetic and genomic potential for hydrogenotrophic, formatotrophic, and acetoclastic methanogenesis in surface-expressed serpentinized fluids of the Samail Ophiolite
Published 2025-01-01“…These results demonstrate the applicability of an energy availability framework for interpreting methanogen ecology in serpentinizing systems.…”
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52537
Combatting Salmonella: a focus on antimicrobial resistance and the need for effective vaccination
Published 2025-01-01“…Strengthening surveillance systems and promoting collaborative global efforts are essential to effectively control and reduce the burden of Salmonella.…”
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52538
Integrating microplastic research in sustainable agriculture: Challenges and future directions for food production
Published 2025-06-01“…Microplastics (MPs) have been identified as modifiers of plant physiology; therefore, these particles present a risk to the quality and safety of plant food production systems. One relevant question is how these emerging pollutants interact with the increasingly extreme environmental conditions of today. …”
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52539
The clean analysis process of Mn2+ for industries: a comparative study on direct determination of high-concentration Mn2+ in solution using spectrophotometry
Published 2025-01-01“…The EC method’s minimal time consumption and cost-effectiveness make it suitable for automation and integration into industrial systems for continuous, real-time monitoring. This research offers valuable insights into high-concentration Mn2+ determination using spectrophotometry, highlighting the EC method’s potential for real-time monitoring and its adaptability for large-scale industrial operations. …”
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52540
Role of digital technology in epidemic control: a scoping review on COVID-19 and Ebola
Published 2025-01-01“…Future efforts should focus on integrating digital solutions into health systems, ensuring equitable access and addressing ethical concerns. …”
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