Real-World Outcomes of Pralsetinib in RET Fusion-Positive NSCLC by Francesca Lucibello, MD, Valérie Gounant, MD, PhD, Mihaela Aldea, MD, PhD, Michaël Duruisseaux, MD, PhD, Maurice Perol, MD, Christos Chouaid, MD, Jaafar Bennouna, MD, PhD, Vincent Fallet, MD, Aldo Renault, MD, Florian Guisier, MD, PhD, Etienne Giroux-Leprieur, MD, PhD, Marie Wislez, MD, PhD, Anne-Claire Toffart, MD, PhD, Julien Mazieres, MD, PhD, Clémence Basse, MD, PhD, Nadia Hegarat, PhD, Matthieu Carton, MD, Nicolas Girard, MD, PhD

“…Objective response rate was 68% (95% CI: 50%–82%), and disease control rate was 89% (95% CI: 75%–97%). Subsequent line of systemic therapy was initiated in 11 patients. Median overall survival from pralsetinib initiation was 23.8 (95% CI: 16.5–not reached) months. …”
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Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping by Shaghayegh Soleimani, Shaghayegh Soleimani, Ozgur Albayrak, Kayra Somay, Hong Yang, Buket Yigit, Burge Ulukan, Dila Atak, Murat Akyildiz, Metehan Gursoy, Elif Demirtas, Adil Mardinoglu, Adil Mardinoglu, Atay Vural, Atay Vural, Murat Dayangac, Mujdat Zeybel

“…BackgroundChronic liver disease due to alcohol-related liver disease and chronic viral hepatitis pose a substantial burden on healthcare systems. Chronic liver disease may predispose to hepatocellular carcinoma, for which therapeutic options are limited. …”
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Biomechanics Parameters of Gait Analysis to Characterize Parkinson’s Disease: A Scoping Review by Michela Russo, Marianna Amboni, Noemi Pisani, Antonio Volzone, Danilo Calderone, Paolo Barone, Francesco Amato, Carlo Ricciardi, Maria Romano

“…The main findings of our review highlighted the use of optoelectronic systems for recording kinematic parameters and force plates for measuring kinetic parameters, due to their high accuracy. …”
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Machine-learning versus traditional methods for prediction of all-cause mortality after transcatheter aortic valve implantation: a systematic review and meta-analysis by Clara K Chow, Aravinda Thiagalingam, Rohan Jayasinghe, Sarah Zaman, Stephen Bacchi, Justin Chan, Aashray Gupta, Shaun Evans, Pramesh Kovoor, Brandon Stretton, Jayme Bennetts, Ammar Zaka, Naim Mridha, Joshua Kovoor, Gopal Sivagangabalan, Cecil Mustafiz, Daud Mutahar, Shreyans Sinhal, James Gorcilov, Benjamin Muston, Fabio Ramponi, Dale J Murdoch

“…While integration of ML algorithms into electronic healthcare systems may improve periprocedural risk stratification, immediate implementation in the clinical setting remains uncertain. …”
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Transformer-based travel time estimation method for plateau and mountainous environments by Guangjun Qu, Kefa Zhou, Rui Wang, Dong Li, Yingpeng Lu, Zhihong Lv, Dequan Zhao, Aijun Zhang, Qing Zhang

“…Abstract Travel time estimation (TTE) is a critical function in intelligent driving systems. Current research and applications related to TTE primarily focus on urban environments. …”
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Mapping groundwater potential zone by robust machine learning algorithms & remote sensing techniques in agriculture dominated area, Bangladesh by M. M. Shah Porun Rana, Muhammad Tauhidur Rahman, Md Fuad Hassan

“…Several machine learning algorithms and analytical hierarchy process (AHP) models along with geographic information systems (GIS) software integrate sixteen thematic layers, including elevation, slope, soil types, topographic wetness index (TWI), normalized difference water index (NDWI), normalized difference vegetation index (NDVI), curvature, soil permeability, physiography, topographic position index (TPI), terrain roughness index (TRI), stream power index (SPI), distance from river, rainfall, drainage density, and land use land cover (LULC) to create a groundwater potential zone map. …”
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A mixed methods crossover randomized controlled trial exploring the experiences, perceptions, and usability of artificial intelligence (ChatGPT) in health sciences education by Mirella Veras, Joseph-Omer Dyer, Holly Shannon, Bryce J M Bogie, Morgan Ronney, Harmehr Sekhon, Derek Rutherford, Paulo Goberlânio Barros Silva, Dahlia Kairy

“…Results Easiness of learnability for personal use and a perception of quick learnability towards ChatGPT-3.5 were significantly higher, compared to conventional online tools from the Systems Usability Scale. Qualitative results highlighted strong benefits of ChatGPT-3.5, such as being a tool for increased overall productivity and brainstorming. …”
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Investigating the effect of electric field amplitude on the thermal behavior of paraffin/Cu nanostructure in a tube containing non-connected rotating ribs using molecular dynamics... by Ahmed Shawqi Sadeq, Rassol Hamed Rasheed, Shaima Albazzaz, Mohammad N. Fares, Soheil Salahshour, Rozbeh Sabetvand

“…These findings have practical implications for optimizing materials in thermal management and energy storage systems by tailoring electric field conditions to enhance performance.…”
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Synergistic thermal and surface area properties of Al2O3–TiO2/water hybrid nanofluids by Yokanan Gustino Djentoe, Farrel Yoga Widiasto, Hilbran Tama Dida Effendi, Musabbikhah, Sri Hartati, Budi Santoso, Budi Kristiawan, Agung Tri Wijayanta

“…The potential of hybrid nanofluids in long-term thermal management systems is demonstrated in this case study.…”
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Extraction, Chemical Composition and Antidiabetic Potential of Crude Polysaccharides from Centella asiatica (L.) Urban by Meng Li, Muhammad Shahid, Xiaobin Zhang, Douglas Law, Mukram Muhammad Mackeen, Arnida Hani Teh, Ahmad Abdul Kareem Najm, Shazrul Fazry, Babul Airianah Othman

“…The global prevalence of diabetes mellitus (DM) is escalating, posing a significant challenge to human healthcare systems. In the present study, mineral and monosaccharide compositions, and antidiabetic potential of polysaccharide fractions separated from Centella asiatica (L.) leaves (CAL) were assessed. …”
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Random-Parameter Multivariate Negative Binomial Regression for Modeling Impacts of Contributing Factors on the Crash Frequency by Crash Types by Chenzhu Wang, Fei Chen, Jianchuan Cheng, Wu Bo, Ping Zhang, Mingyu Hou, Feng Xiao

“…Road geometry plays a critical role in dynamic driving systems. Contributing factors such as plane, longitudinal alignment, and traffic volume, as well as drivers’ sight characteristics, determine the safe operating speed of cars and trucks. …”
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Electroacupuncture and Tongbian decoction ameliorate CUMS-induced depression and constipation in mice via TPH2/5-HT pathway of the gut-brain axis by Yi Chen, Peihua Shen, Qi Li, Shun Seng Ong, Yunzhi Qian, Hai Lu, Ming Li, Tianshu Xu

“…In conclusion, EA + TB regulates the TPH2/5-HT pathway via the gut-brain axis, demonstrating synergistic regulation of the nervous and gastrointestinal systems, with favorable antidepressant and prokinetic effects.…”
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Targeting Cytokine Storm in COVID-19: A Role of Online Hemodiafiltration with Asymmetric Cellulose Triacetate in Maintenance Hemodialysis Patients—A Report of 10 Cases by José C. De La Flor, Francisco Valga, Alexander Marschall, Tania Monzon, Cristina Albarracín, Elisa Ruiz, Miguel Rodeles

“…Furthermore, we evaluate the removal of hyperinflammatory parameters with the ATA membrane in postdilution online hemodiafiltration (OL-HDF) in these patients through a variety of biomarkers of systemic inflammation from the diagnosis until stripping. …”
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Nurse management of minor problems in primary care emergencies: a non-randomized controlled trial by Jordi Estarlich-Corominas, Neus Soler-Abril, Anna Casanellas-Chuecos, Sara Becerra-Corzo, Andrea Sofia Bianco, Pere Torán-Monserrat, Rosa García-Sierra

“…Abstract Background Health systems must implement strategies to adapt to the high demand in primary care caused by social changes. …”
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The Association Between Periodontitis, Gingivitis, Tooth Loss and Stroke: An Umbrella Study with Meta-Analysis by Jad El Masri, Ahmad Al Malak, Diala El Masri, Maya Ghazi, Silva Al Boussi, Yasmina El Masri, Mohammad Hassoun, Maryam Tlayss, Pascale Salameh, Hassan Hosseini

“…Periodontal diseases (PD) have a modifiable role in causing CVA, where several studies suggested direct or indirect correlations with systemic diseases. This study aims to summarize, evaluate and analyze all the evidence available in literature, to reach a better understanding of the relation between periodontitis, gingivitis, tooth loss and CVA. …”
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Epidemiology of Pediatric Traumatic Brain Injury at Sylvanus Olympio University Hospital of Lomé in Togo by Pilakimwe Egbohou, Tabana Mouzou, Pikabalo Tchetike, Hamza Doles Sama, Sarakawabalo Assenouwe, Gnimdou Akala-Yoba, Lonlongnon Randolph, Kadjika Tomta

“…Factors associated with mortality were secondary systemic insults, worse GCS < 6, and ISS > 20.…”
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Should you hold onto the treadmill handrails or not? Cortical evidence at different walking speeds by Monica Biggio, Costanza Iester, Davide Cattaneo, Simone Cutini, Ambra Bisio, Ludovico Pedullà, Alessandro Torchio, Marco Bove, Laura Bonzano

“…The use of handrails embedded in treadmill systems is debated, and current literature only explores the issue from a behavioral perspective. …”
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Evaluation of Five Ready-to-Use Bases for the Topical Administration of Propranolol Hydrochloride to Treat Infantile Hemangioma by Chiara Lacassia, Annalisa Cutrignelli, Flavia Maria la Forgia, Sergio Fontana, Antonio Lopalco, Nunzio Denora, Angela Assunta Lopedota

“…Although oral propranolol therapy at a dosage of 3 mg/kg/die is effective, it can cause systemic adverse reactions. This therapy is not necessarily applicable to all patients. …”
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Do dogs preferentially encode the identity of the target object or the location of others’ actions? by Lucrezia Lonardo, Christoph J. Völter, Robert Hepach, Claus Lamm, Ludwig Huber

“…Future research will need to further probe the suitability of anticipatory looking as measure of dogs’ socio-cognitive abilities given differences between the visual systems of dogs and primates.…”
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Implication of IL-17 in Bone Loss and Structural Damage in Inflammatory Rheumatic Diseases by Benoit Le Goff, Béatrice Bouvard, Thierry Lequerre, Eric Lespessailles, Hubert Marotte, Yves-Marie Pers, Bernard Cortet

“…Proinflammatory cytokines play an important role in the systemic and focal bone loss associated with chronic inflammatory diseases. …”
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