Loss of flavonoids homeostasis leads to pistillody in sua-CMS of Nicotiana tabacum by Jie Xu, Zhuo Wei, Jugou Liao, Keliang Tao, Junpeng Zhang, Yu Jiang, Yongzhi Niu, Yunye Zheng, Limeng Zhang, Xuemei Wei

“…This phenomenon is widely present in plants, and might be induced by intracellular communication (mitochondrial retrograde signaling), but its systemic regulating mechanism is still unclear. In this study, morphological observation showed that the stamens transformed into pistil-like structures, leading to flat and dehiscent pistils, and fruit set decrease in sua-CMS (MS K326, somatic fusion between Nicotiana. tabacum L. …”
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Prognostic Factors on the Graft-versus-Host Disease-Free and Relapse-Free Survival after Adult Allogeneic Hematopoietic Stem Cell Transplantation by Yao-Chung Liu, Sheng-Hsuan Chien, Nai-Wen Fan, Ming-Hung Hu, Jyh-Pyng Gau, Chia-Jen Liu, Yuan-Bin Yu, Liang-Tsai Hsiao, Tzeon-Jye Chiou, Cheng-Hwai Tzeng, Po-Min Chen, Jin-Hwang Liu

“…A novel composite endpoint of GVHD-free/relapse-free survival (GRFS) in which events include grades 3-4 acute GVHD, chronic GVHD requiring systemic therapy, relapse, or death is censored to completely characterize the survival without mortality or ongoing morbidity. …”
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Dysregulated Circulating Dendritic Cell Function in Ulcerative Colitis Is Partially Restored by Probiotic Strain Lactobacillus casei Shirota by Elizabeth R. Mann, Jialu You, Verena Horneffer-van der Sluis, David Bernardo, Hafid Omar Al-Hassi, Jon Landy, Simon T. Peake, Linda V. Thomas, Cheng T. Tee, Gui Han Lee, Ailsa L. Hart, Parveen Yaqoob, Stella C. Knight

“…Conclusions. We demonstrate a systemic, dysregulated DC function in UC that may account for the propensity of UC patients to develop cutaneous manifestations. …”
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Evaluation of Cyclic Fatigue of Hyflex EDM, Twisted Files, and ProTaper Gold Manufactured with Different Processes: An In Vitro Study by Pooja D. Khandagale, Prashant P. Shetty, Saleem D. Makandar, Pradeep A. Bapna, Mohmed Isaqali Karobari, Anand Marya, Pietro Messina, Giuseppe Alessandro Scardina

“…Hence, it is of immense importance to know which file systems have more cyclic fatigue resistance. Methodology. …”
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Maximizing zearalenone removal: Unveiling the superior efficiency of pre-treated carbon in adsorption and photocatalysis by J.C. Gómez-Vilchis, G. García-Rosales, L.C. Longoria-Gándara, E.O. Pérez-Gómez, D. Tenorio-Castilleros

“…To prevent its release into aquatic systems, effective tertiary treatment methods are essential. …”
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Sexual and reproductive health and rights, HIV and migration in southern Africa: A rapid review by G Musuka, I Chingombe, E Moyo, T Chikava, B Moyo, M Mapingure, H Musuka, T Dzinamarira

“…Projects ranged from peer-education interventions to community-based referral systems, aiming to improve knowledge, access and outcomes related to SRH and HIV. …”
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Integrative transcriptome profiling for identifying ALS potential treatment using the drug repurposing approach by Navid Kashani, Amir Sabbaghian, Fatemeh EmamiPari, Mohammad Khalili Gorjimahalleh, Mahdi Aalikhani

“…Thus, we here attempted to identify crucial genetic biomarkers through transcriptome profiling and systems biology methodologies to advance our knowledge of the diagnosis and pathogenesis of ALS. …”
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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome. by Brittany E Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L Underwood, Jun Hyoung Park, Huihui Fan, Julian A Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K Berg, Danielle A Bazer, Christopher Vellano, Philip Jones, Holger K Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L Wang, Dung-Fang Lee

“…Inhibition of mitochondrial respiratory complex I activity by IACS-010759 selectively suppressed cellular respiration and cell proliferation of RTS osteoblasts. Furthermore, systems analysis of IACS-010759-induced changes in RTS osteoblasts revealed that chemical inhibition of mitochondrial respiratory complex I impaired cell proliferation, induced senescence, and decreased MAPK signaling and cell cycle associated genes, but increased H19 and ribosomal protein genes. …”
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Lack of HLH in FMF by Ozge Basaran, Erdal Sag, Elif Arslanoglu Aydın, Busra Aydın, Nur Kübra Tasdemir, Elif Celikel, Yagmur Bayındır, Semanur Özdel, Yelda Bilginer, Alexei A Grom, Seza Ozen

“…Abstract Background Macrophage activation syndrome (MAS) is a severe complication of systemic juvenile idiopathic arthritis (sJIA), driven by excessive activation of T cells and macrophages, resulting in a cytokine storm. …”
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Temporal variability of dissolved inorganic nitrogen and key environmental drivers in a dam-induced subtropical urban lake by Peng Tang, Boyu Ren, Tianyang Li, Qiwen Xu, Baoxiang Yang, Shunyao Zhu, Binghui He

“…The dissolved inorganic nitrogen (DIN) is a critical indicator of the organism growth and ecological balance within aquatic systems. Various water quality determinants influence the temporal variations in DIN concentration, making the identification of key drivers essential for a deeper understanding of nutrient cycling and the formulation of targeted management strategies. …”
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Spleno-Mesenteric Venous Blood Flow Dynamics in Adult Patients with Chronic Portal Vein Thrombosis Analyzed by Sequential CT-Spleno- and Mesenterico-Portography by Alexandra Schlitt, Andrea Goetz, Christian Stroszczynski, Florian Zeman, Christina Hackl, Hans J. Schlitt, Ernst-Michael Jung, Wibke Uller, Simone Hammer

“…In patients without PVCT, small bowel varices were fed by both systems or the SMV, while in patients with PVCT they were fed by the SMV (<i>p</i> = 0.031). …”
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Nanostructured, Self-Assembling Peptide K5 Blocks TNF-α and PGE2 Production by Suppression of the AP-1/p38 Pathway by Woo Seok Yang, Yung Chul Park, Ji Hye Kim, Hye Ri Kim, Tao Yu, Se Eun Byeon, Larry D. Unsworth, Jaehwi Lee, Jae Youl Cho

“…Nanostructured, self-assembling peptides hold promise for a variety of regenerative medical applications such as 3D cell culture systems, accelerated wound healing, and nerve repair. …”
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Challenges Faced by Migrant Students in Education: A Comprehensive Analysis of Legal, Psychological, and Economic Barriers by Khasanboy Abdusamatov, Dinara Babajanova, Dilshodjon Egamberdiev, Yunus Xodjiyev, Uktamjon Tukhtaev, Nodirbek Yusupov, Sitora Shoislomova

“…In addition, 50 in-depth interviews with educators, policy makers, and migration experts were conducted to gain insights into systemic issues. The study revealed that migrant students face significant challenges across all three dimensions—legal, psychological, and economic. …”
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Dynamics of salt intrusion in complex estuarine networks: an idealised model applied to the Rhine–Meuse Delta by B. Biemond, W. M. Kranenburg, W. M. Kranenburg, Y. Huismans, Y. Huismans, H. E. de Swart, H. A. Dijkstra

“…We identify and quantify the characteristics of salt intrusion in such systems using an idealised model. The Rhine–Meuse Delta is selected as a prototype example of a complex network with many channels. …”
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Extreme Environment Streptomyces: Potential Sources for New Antibacterial and Anticancer Drug Leads? by Periyasamy Sivalingam, Kui Hong, John Pote, Kandasamy Prabakar

“…Most of the drugs currently used in the health care systems were of Streptomyces origin or their synthetic forms. …”
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Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits by A. M. A. M. Zonaed Siddiki, Gous Miah, Md. Sirazul Islam, Mahadia Kumkum, Meheadi Hasan Rumi, Abdul Baten, Mohammad Alamgir Hossain

“…The availability of reference whole-genome assembly of goats, annotated genes, and transcriptomics makes comparative genomics a useful tool for systemic genetic upgradation. Identification and characterization of trait-associated sequence variations and gene will provide powerful means to give positive influences for future goat breeding program.…”
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Feature selection enhances peptide binding predictions for TCR-specific interactions by Hamid Teimouri, Hamid Teimouri, Zahra S. Ghoreyshi, Zahra S. Ghoreyshi, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Anatoly B. Kolomeisky, Jason T. George, Jason T. George, Jason T. George, Jason T. George

“…To evaluate our approach across different TCR systems, we utilized a dataset that includes peptide libraries tested against three distinct murine TCRs. …”
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CMACGSA: Improved Gravitational Search Algorithm Based on Cerebellar Model Articulation Controller for Optimization by Nazmiye Ebru Bulut, Emre Dandil, Ugur Yuzgec, Alpaslan Duysak

“…These algorithms often take inspiration from natural phenomena, systems or biological behaviour to find optimal solutions. …”
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Current scenario of emerging pollutants in farmlands and water reservoirs: Prospects and challenges by Muhammad Fahad Sardar, Fazila Younas, Hongna Li, Jawad Ali, Pengcheng Zhu, Xiaona Yu, Zhaojie Cui, Weihua Guo

“…Numerous methods have been developed to address this emerging issue, including electrochemical degradation, advanced oxidation processes, photocatalytic degradation, biosurfactants, micro- and nano-bubble systems, ultrasonic cavitation, nanotechnology, constructed wetlands, and many hybrid approaches. …”
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Rainfall forecasts, learning subsidies and conservation agriculture adoption: Experimental evidence from Zambia by Hambulo Ngoma, Esau Simutowe, João Vasco Silva, Isaiah Nyagumbo, Kelvin Kalala, Mukwemba Habeenzu, Christian Thierfelder

“…Adapting smallholder rainfed farming systems to climate change requires adoption of technologies that build resilience to climate shocks. …”
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