Prolonged Cardiopulmonary Bypass Time-Induced Endothelial Dysfunction via Glypican-1 Shedding, Inflammation, and Matrix Metalloproteinase 9 in Patients Undergoing Cardiac Surgery by Shiyi Li, Katherine V. Nordick, Iván Murrieta-Álvarez, Randall P. Kirby, Rishav Bhattacharya, Ismael Garcia, Camila Hochman-Mendez, Todd K. Rosengart, Kenneth K. Liao, Nandan K. Mondal

“…Conclusions: A prolonged CPB triggers a systemic inflammatory response and activates MMP9, leading to glypican-1 shedding and endothelial dysfunction.…”
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Experimental approach to obtaining subcutaneous xenograft of non-small cell lung cancer by E. A. Lukbanova, M. V. Mindar, E. A. Dzhenkova, A. Yu. Maksimov, A. S. Goncharova, Yu. S. Shatova, A. A. Maslov, A. V. Shaposhnikov, E. V. Zaikina, Yu. N. Lazutin

“…The created PDX models can be recommended as test systems for preclinical studies of the effectiveness of new pharmacological substances with potential antitumor activity.…”
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Enhancing Maize Production Through Timely Nutrient Supply: The Role of Foliar Fertiliser Application by Brian Ssemugenze, Akasairi Ocwa, Ronald Kuunya, Costa Gumisiriya, Csaba Bojtor, János Nagy, Adrienn Széles, Árpád Illés

“…Foliar fertilisation offers a complementary method to traditional soil fertilisation amongst resource-limited agricultural systems, providing a more efficient solution to nutrient deficiencies, especially in suboptimal soil conditions. …”
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Sevoflurane Preconditioning plus Postconditioning Decreases Inflammatory Response with Hemodynamic Recovery in Experimental Liver Ischemia Reperfusion by Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Cinthia Lanchotte, Ana Maria Mendonça Coelho, Mauro Nakatani, Eduardo Ryoiti Tatebe, Jonathan Augusto Venceslau Lima, Camilla Oliveira Mendes, Bruno Camargo Rocha Paim de Araujo, Emilio Elias Abdo, Luiz Carneiro D’Albuquerque, Flavio Henrique Ferreira Galvão

“…Furthermore, sevoflurane postconditioning promoted systemic hemodynamic recovery with a decrease in inflammatory response.…”
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Keratin/chitosan film promotes wound healing in rats with combined radiation-wound injury by Yu-mei Wang, Tong Xin, Hao Deng, Jie Chen, Shen-lin Tang, Li-sheng Liu, Xiao-liang Chen

“…A rat model of combined radiation-wound injury was employed to evaluate the therapeutic efficacy of the KRT/CS film. Finally, the systemic biotoxicity of KRT/CS film was assessed through histological analysis. …”
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Uncertainty Analysis of Biogas Generation and Gas Hydrate Accumulations in the Baiyun Sag, South China Sea by Pibo Su, Jinqiang Liang, Huai Cheng, Yaoyao Lv, Wei Zhang, Zuofei Zhu

“…In this study, we use petroleum systems modeling (PSM) to quantitatively simulate the uncertainty of biogenic gas generation modes and their impact on the spatial distribution and resource assessment of gas hydrates in the Baiyun Sag, South China Sea. …”
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Genomic Insight into <i>Vibrio</i> Isolates from Fresh Raw Mussels and Ready-to-Eat Stuffed Mussels by Artun Yibar, Muhammed Duman, Hilal Ay, Nihed Ajmi, Gorkem Tasci, Fatma Gurler, Sabire Guler, Danny Morick, Izzet Burcin Saticioglu

“…The presence of nine different biosynthetic gene clusters (BGCs), 27 prophage regions, and eight CRISPR/Cas systems in 15 <i>Vibrio</i> strains provides information about their potential pathogenicity, survival strategies, and adaptation to different habitats. …”
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A Weighted Bayesian Kernel Machine Regression Approach for Predicting the Growth of Indoor-Cultured Abalone by Seung-Won Seo, Gyumin Choi, Ho-Jin Jung, Mi-Jin Choi, Young-Dae Oh, Hyun-Seok Jang, Han-Kyu Lim, Seongil Jo

“…These findings underscore the potential of advanced machine learning techniques in enhancing aquaculture practices and offer a robust framework for managing complex, multi-variable systems in sustainable farming.…”
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Directly Gel‐Thermal Processing of Linker‐Mixed Crystal‐Glass Composite Membranes for Sorption‐Preferential Gas Separation by Yihao Xiao, Yanqing Yu, Xinxi Huang, Da Chen, Wanbin Li

“…The membranes exhibit outstanding gas separation performance for the challenging systems of CH4/N2 and O2/N2, with mixture selectivities up to 9.3 and 9.6, respectively, far exceeding those of polymer, MOF, and mixed‐matrix membranes. …”
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Soil health of bananas cultivated in Ribeira River Valley – the major producing region of Brazil by Cavalieri-Polizeli Karina Maria Vieira, da Silva Anderson Lucas, Cremonesi Marcus, Lima Juliana Domingues, Cipriano Patriciani Estela, Cherubin Maurício Roberto, Rozane Danilo Eduardo

“…All soil quality indexes tested here can be used to verify soil health; however, soil quality index-2 was the best for a total dataset, and soil management assessment framework was the best for a minimum dataset, demonstrating no statistical difference in soil health between banana and forest soil systems.…”
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Frontal Face Generation Based on Attitude Point Guidance and Attention Mechanism Improvement by Jihui Zhao, Zhengyi Yuan, Junhu Zhang, Haitao Li, Hui Li

“…The deflection of face angle is the most important factor affecting the accuracy in face recognition, non-frontal faces make some face recognition systems lose their due functions, the existing frontal face conversion methods often have the phenomenon of distortion and lack of identity. …”
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Anaesthetic Management of a Neonate with Ebstein’s Anomaly Undergoing a Meningomyelocele Surgery: A Case Report by Prakriti, Monika Yadav, Vaishali Gupta, Komal Yadav, Shikha Garg

“…Key cardiovascular goals for this patient included maintaining normal sinus rhythm, ensuring adequate preload while avoiding significant changes in Systemic Vascular Resistance (SVR) or PVR, avoiding medications and factors that depress myocardial function, and promptly identifying haemodynamic instability or inadequate tissue perfusion with appropriate corrections. …”
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Protective Effect of Liposome-Encapsulated Glutathione in a Human Epidermal Model Exposed to a Mustard Gas Analog by Victor Paromov, Sudha Kumari, Marianne Brannon, Naga S. Kanaparthy, Hongsong Yang, Milton G. Smith, William L. Stone

“…Liposomes containing water-soluble antioxidants and/or lipid-soluble antioxidants were evaluated using in vitro model systems. Initially, we found that liposomes containing encapsulated glutathione (GSH-liposomes) increased cell viability and attenuated production of reactive oxygen species (ROS) in HaCaT cells exposed to CEES. …”
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Temporal and spatial characterization of keratinocytes supporting orf virus replication by Byung-Joon Seung, Sushil Khatiwada, Daniel L. Rock, Gustavo Delhon

“…Keratinocytes, the main cells of the epidermis, are found in different stages of a differentiation program that produces the critical barrier against environmental damage. While systemic poxviruses (e.g. smallpox virus, sheeppox virus) also infect other cell types, the parapoxvirus orf virus (ORFV), which causes localized infections in sheep and goats, has not been shown to replicate in cells other than keratinocytes. …”
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Generation of transgenic chicken through ovarian injection by Jinghua Jiang, Caiying Wang, Xuguang Du, Fei Gao, Sen Wu

“…This technique simplifies the transgenic process for chickens and has the potential to be adapted for other avian species, especially those without established PGCs culture systems.…”
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Exploring damped and undamped frequencies in beam structures with viscoelastic supports using GFEM and state-space formulation by Gulnaz Kanwal, Hani Alahmadi, Rab Nawaz, Tayyab Nawaz

“…Additionally, the study introduces the application of state-space formulations combined with the Runge–Kutta method (RK4) to precisely analyze the response of damped systems, which adds significant value in exploring complex beam dynamics. …”
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Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…The incidence of cancer continues to increase worldwide, resulting in significant physical, emotional, and financial challenges for individuals, families, communities, and healthcare systems. Cancer is projected to be responsible for approximately 10 million deaths in 2020, accounting for one in six deaths globally. …”
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Mendelian randomization analysis does not support a causal influence between lipoprotein(A) and immune-mediated inflammatory diseases by Yun Ti, Dan Xu, Xiaoning Qin, Yang Hu, Yuru Xu, Qingzhao Zhao, Peili Bu, Jingyuan Li

“…We performed a bidirectional two-sample mendelian randomization analyses based on genome-wide association study (GWAS) summary statistics of Lp(a) and nine IMIDs, specifically celiac disease (CeD), Crohn’s disease (CD), ulcerative colitis (UC), inflammatory bowel disease (IBD), multiple sclerosis (MS), psoriasis (Pso), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), type 1 diabetes (T1D), and summary-level data for lipid traits. …”
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Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus by Xinai Han, Xiaoming Zhang, Rui Song, Shiqi Li, Shujing Zou, Quanguang Tan, Tianyang Liu, Shugeng Luo, Zhe Wu, Hongyu Jie, Jinhong Wang

“…Diffuse alveolar haemorrhage (DAH) is a rapidly developing condition owing to a lack of effective treatment and resulting in a high mortality rate in systemic lupus erythematosus (SLE). Neutrophil extracellular traps (NETs) contain numerous antigens and proinflammatory substances that directly damage the vascular endothelium and aggravate vascular inflammation, which is considered an important pathogenic factor of DAH in SLE. …”
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cAMP analogues downregulate the expression of granulocyte macrophage colony-stimulating factor (GM-CSF) in human bone marrow stromal cells in vitro by G. Bug, J. Aman, C. Huber, C. Peschel, H. G. Derigs

“…The stimulation of granulocyte macrophage-colony stimulating factor (GM-CSF) by interleukin-1 (IL-1) has been shown to be counteracted in different mesenchymal cell systems by cyclic adenosine monophosphate (cAMP) agonists. …”
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