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  1. 40541
  2. 40542
  3. 40543

    A fuzzy logic approach within the DPSIR framework to address the inherent uncertainty and complexity of water security assessments by Liang Yuan, Zhijie Zhou, Weijun He, Xia Wu, Dagmawi Mulugeta Degefu, Juan Cheng, Lin Chai, Thomas Stephen Ramsey

    Published 2025-01-01
    “…In this paper, an index system for evaluating and diagnosing water security in the Mekong River Basin (MRB) was constructed based on the DPSIR model. …”
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  4. 40544

    Editorial by Jörg Tremmel, Edward Page, Konrad Ott

    Published 2009-10-01
    “…Combined with other inertias integral to the climate system, the bulk of the expected harm to humans from climate change will be felt by future generations…”
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  5. 40545
  6. 40546

    Understanding experiences of neglected tropical diseases of the skin: a mixed-methods study to inform intervention development in Ethiopia by Michael Marks, David Mabey, Ruth Canter, Elizabeth Allen, Charles Opondo, Jennifer Palmer, Iris Mosweu, Jacob Novignon, Sinéad Langan, Maria Zuurmond, Catherine Pitt, Stephen L Walker, Dorothy Yeboah-Manu, Tara Mtuy, Rachel L Pullan, Richard Phillips, Daniel Okyere, Anthony Ablordey, Samantha Owen, Portia Boakye Okyere, Kidist Bobosha, Katherine Halliday, Steve Walker, Galana Mamo Ayana, Rachel Pullan, Mirgissa Kaba, Tara B Mtuy, Yaw Amoako, Adwoa Asante-Poku, Abigail Agbanyo, Eric Koka, Joseph Timothy, Yohannes Hailemichael, Abebaw Yeshambel Alemu, Teklu Cherkose, Getachew Kebebew, Fikregabrail Aberra Kassa, Tedros Nigusse, Kibur Engedawork, Zenebu Begna, Abay Waday, Saba Lambert, Katherine Elizabeth Halliday, Endalamaw Gadisa, Vanessa Yardley, Collins Ahorlu, Anita Achiaa Gyekye, Emmanuel Afreh, Esther Amon, Abraham Kwabena Anang, Ruth Dede Tuwor, Giulia D’Odorico, Kibur Engidawork, Mehari Getaneh, Bernadette Morkporkpor, Emmanuel Narh, Dorcas Opai-Tetteh, Yohannes Michael, Amel Mohammed, Fewzia Shikur Mohammed, Shimelis Doni Nigusse, Maja Niksic, Edmond Okloo, Michael Oppong, Lucy Owusu, Ishaque Siam, Ingrid Sobel, Feleke Tilahum, Joseph Tuffour, Abay Woday, Abebaw Yeshambel, Adelaide Forkuo- Boadu, Derrick Kontoh, Jojo Cobbinah

    Published 2025-02-01
    “…To inform these strategies, we aimed to understand the social, economic and health system context of skin NTD care in Kalu woreda, Amhara region, Ethiopia, where cutaneous leishmaniasis (CL) and leprosy are endemic.Methods Between October 2020 and May 2022, we surveyed and reviewed records of 41 primary healthcare facilities and explored common disease experiences in focus group discussions (n=40) and interviews with people affected by leprosy (n=37) and CL (n=33), health workers (n=23), kebele authorities and opinion leaders (n=33) and traditional healers (n=7). …”
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  7. 40547
  8. 40548

    Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy by Baijin Xia, Huolun Feng, Xinmiao Jiang, Jialing Guo, Keming Lin, Wenxing Zhang, Fan Xing, Lixue Cao, Yong Li, Hui Zhang, Xu Zhang, Wenyu Li, Fei Yu

    Published 2025-03-01
    “…We fused nanobody (Nb) targeting CD30 and CD5 with GrB and coupled them to human ferritin (h-HFn) using the Gv/Sd system, creating a novel therapeutic nanoparticle named BiCD30/5-GF, which specifically targets CD30 and CD5 receptors on TCL tumor cells. …”
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  9. 40549

    Editorial by Christian Gütl

    Published 2025-01-01
    “…Ulrike Krießmann from the Library of the Graz University of Technology, the TIB - Leibniz Information Centre for Science and Technology University Library in Germany, and the Institute of Interactive Systems and Data Science from TU Graz for their financial support. …”
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  10. 40550

    β-synuclein in cerebrospinal fluid as a potential biomarker for distinguishing human prion diseases from Alzheimer’s and Parkinson’s disease by Bing Xu, Kang Xiao, Xiaoxi Jia, Rundong Cao, Donglin Liang, Ruhan A, Weiwei Zhang, Chunjie Li, Liping Gao, Cao Chen, Qi Shi, Xiaoping Dong

    Published 2025-02-01
    “…Abstract Background β-synuclein (β-syn), mainly expressed in central nerve system, is one of the biomarkers in cerebrospinal fluid (CSF) and blood for synaptic damage, which has been reported to be elevated in CSF and blood of the patients of prion diseases (PrDs). …”
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  11. 40551

    Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae by Chenkai Ge, Zhijun Ye, Weitao Hu, Jingrong Tang, Huimin Li, Fasheng Liu, Xinjun Liao, Jianjun Chen, Shouhua Zhang, Zigang Cao

    Published 2025-01-01
    “…This study expands our understanding of the potential effects of the pesticide pyrazosulfuron-ethyl on injured fish, highlights the link between the immune system and the regeneration process, and demonstrates the potential application of fin regeneration in risk assessments of environmental toxicology to assess drug toxicity.…”
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  12. 40552

    Modern theoretical-methodological and economic-legal problems of implementing the concept of sustainable development of tourism and recreation in Ukraine by Ion Dubovich, Alla Anishchenko, Nadia Yurkiv, Yuliia Volkovska, Rostyslav Matsko, Oleh Rozhkovych, Mariana-Nadiia Dubovich, Oksana Pylypiak

    Published 2024-10-01
    “…It is noted that tourism and recreation in Ukraine is an industry with great potential and prospects, but at the same time it is a complex and dynamic system that covers various regional, ecological, economic, organizational and other aspects.It is emphasized that Ukraine, due to its unique natural resources, rich historical heritage and socio-cultural values, has great potential in the field of tourism and recreation, which creates opportunities for its development throughout the year.It is found that in order to achieve effective results regarding the organization, functioning and development of tourism and recreation, a number of regulatory legal acts were adopted in Ukraine. …”
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  13. 40553

    Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone by Shujing GUO, Li ZHANG

    Published 2025-01-01
    “…Mapping the high temperature disaster risk in the urban development area of Wuhan and analyzing the high temperature disaster risk and influencing factors thereof at the local scale can provide an important basis for the prevention of high temperature disasters in the city.MethodsBased on the “hazard – exposure – vulnerability” high temperature disaster risk assessment framework proposed by the Intergovernmental Panel on Climate Change, this research constructed an assessment system by utilizing multi-source data, and then pre-processes all relevant indicators to make them dimensionless. …”
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  14. 40554
  15. 40555
  16. 40556

    Proteomic analysis to explore potential mechanism underlying pseudomale sperm defect in Cynoglossus semilaevis by Xihong Li, Lu Li, Zhongkai Cui, Ming Li, Xuexue Sun, Zhijie Li, Zhangfan Chen, Lanqing Ding, Dongdong Xu, Wenteng Xu

    Published 2025-03-01
    “…Dysfunction of chaperones targeting client polypeptides for degradation via the ubiquitin-proteasome system (UPS) or ferroptosis might be a possible cause of pseudomale sperm abnormalities. …”
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  17. 40557
  18. 40558

    Efficacy of Streptococcus agalactiae vaccine strains N3M and N4M in fry tilapia infected by different strains of S. agalactiae by Sukenda, Sukenda, Arif Lukman Firmansyah, Rahman, Rahman, Sri Nuryati, Dendi Hidayatullah

    Published 2018-07-01
    “…This study aimed to analyze a specific and nonspecific immune system in fry tilapia that has been given with S. agalactiae vaccine from N3M and N4M strain and examine the protective immunity against S. agalactiae N3M, N4M, N17O, NK1,  and N14G strains infection. …”
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  19. 40559

    Evaluation of Urban Composite Carbon Sink Value: A Case Study of Shenyang by Tiemao SHI, Di WANG, Yu TANG, Peiying LI

    Published 2025-01-01
    “…ObjectiveIn view of the urgent necessity to achieve the carbon peaking and carbon neutrality goals and establish an effective ecological compensation system, it is of crucial significance to evaluate the carbon sink value. …”
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  20. 40560

    Podophyllotoxin mediates hepatic toxicity via the C5a/C5aR/ROS/NLRP3 and cGMP/PKG/mTOR axis in rats based on toxicological evidence chain (TEC) concept by phosphoproteomic analysis by Chuanxin Liu, Xiaobin Huang, Jiao Kong, Xuejiao Li, Yuming Wang, Fangfang Zhang, Jiajia Duan

    Published 2025-01-01
    “…Conclusion: PPT activates the complement system through the C5a/C5aR/ROS/NLRP3 pathway and induces the formation of inflammasomes, promoting pyroptosis. …”
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