A Metapopulation Model to Assess Water Management Impacts on the Threatened Australian Lungfish, <i>Neoceratodus forsteri</i> by Charles R. Todd, Andrew J. McDougall, Scott M. C. Raymond, Robin Hale, Timothy R. Brown, John D. Koehn, Henry F. Wootton, Steven G. Brooks, Adrian M. Kitchingman, Tom Espinoza, Benjamin G. Fanson, Peter K. Kind, Sharon M. Marshall, David T. Roberts

“…Our modeling approach substantially advances conservation management of this species, as it can be adapted to suit other populations in other river systems and used to test sensitivity to recovery actions.…”
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Analisis Kualitas Website Balai Besar Taman Nasional Gunung Gede Pangranggo (BBTNGGP) menggunakan Metode Webqual 4.0 by Muhammad Syahid Qadhafi, Atit Pertiwi

“…Dengan harapan mengetahui tingkat kualitas layanan website Balai Besar Taman Nasional Gunung Gede Pangranggo dari persepsi pengguna akhir dengan menganalisis system yang sesuai harapan para penggunanya.   Abstract In this century the use of information technology has become a crucial need for each individual, organization, education, business to government. …”
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A comprehensive, population level evaluation of previously reported drug triggers of pemphigus highlights immunomodulatory capacity as a common characteristic by Justin Baroukhian, Kristina Seiffert-Sinha, Animesh A. Sinha

“…FindingsIn this series of observational, retrospective, case-control, pharmacovigilance analyses of the FDA Adverse Event Reporting System, the odds of reporting the adverse event pemphigus were significantly elevated among individuals exposed to 11/36 previously reported trigger drugs namely, gold sodium thiomalate, penicillamine, piroxicam, rifampin, hydroxychloroquine, imiquimod, hydrochlorothiazide, irbesartan, lisinopril, nivolumab, and nifedipine.MeaningEnvironmental exposures such as drugs are relevant players in the pathogenesis of autoimmune diseases and clinicians who treat patients with autoimmune blistering diseases such as pemphigus should consider performing a detailed medication history leveraging this information regarding deleterious drug-disease interactions at initial evaluation as well as longitudinal monitoring of patients to better inform clinical care decisions.ImportancePemphigus vulgaris (PV) is a rare, potentially fatal autoimmune disease with pathogenic contributions from both genetic as well as environmental factors, notably drug exposures. …”
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Role of PI3K/AKT/mTOR signaling pathway and sirtuin genes in chronic obstructive pulmonary disease development by G. F. Korytina, L. Z. Akhmadishina, V. A. Markelov, Y. G. Aznabaeva, O. V. Kochetova, T. R. Nasibullin, A. P. Larkina, N. N. Khusnutdinova, N. Sh. Zagidullin, T. V. Victorova

“…Chronic obstructive pulmonary disease (COPD) is a multifactorial disease of the respiratory system which develops as a result of a complex interaction of genetic and environmental factors closely related to lifestyle. …”
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High-accuracy crRNA array assembly strategy for multiplex CRISPR by Xiangtong Zhao, Lixian Yang, Peng Li, Zijing Cheng, Yongshi Jia, Limin Luo, Aihong Bi, Hanchu Xiong, Haibo Zhang, Hongen Xu, Jinrui Zhang, Yaodong Zhang

“…Simultaneous targeting of multiple loci with the CRISPR system, a tool known as multiplex CRISPR, offers greater feasibility for manipulating and elucidating the intricate and redundant endogenous networks underlying complex cellular functions. …”
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Perancangan User Experiance Website Travel Mabruro Menggunakan Pendekatan Human-Centered Design by Safira Nur Rahmah, Hanifah Muslimah Az- Zahra, Yusi Tyroni Mursityo

“…Focusing on producing a service system that can be useful and beneficial by involving humans (in this case users and stakeholder) which aims to meet the needs and satisfaction of users and also achieve organizational goals that are previously planned. …”
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Clinical Characteristics During and After COVID‐19 Infection Among Healthcare Workers During the First Wave of Omicron in Chongqing, China by Haoling Tang, Zhiwei Chen, Tianquan Huang, Pingping Yu, Qiao Tang, Yue Qiu, Yunling Xue, Jing Tang, Nan Cai, Hong Ren, Mingli Peng, Peng Hu

“…These symptoms can be further categorized into five groups: fever type, upper respiratory tract type, influenza type, digestive system type, and systemic type—all showing complex and diverse patterns. …”
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Fhl1, a new spatially specific protein, regulates vein graft neointimal hyperplasia by Chaoqun Wang, Jiantao Chen, Zicong Feng, Bohao Jian, Suiqing Huang, Kangni Feng, Haoliang Liu, Zhuoming Zhou, Ziyin Ye, Jing Lu, Mengya Liang, Zhongkai Wu

“…Conclusion These findings indicate that, following grafting into the arterial system, the newly formed repair cells external to the grafted vein play a pivotal role in NIH, with neointimal cells exhibiting stable and continuous Fhl1 expression. …”
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Do doctors in dispensing practices with a financial conflict of interest prescribe more expensive drugs? A cross-sectional analysis of English primary care prescribing data by Ben Goldacre, Carl Reynolds, Anna Powell-Smith, Alex J Walker, Tom A Yates, Richard Croker, Liam Smeeth

“…This is the largest study ever conducted on dispensing practices, and the first contemporary research suggesting some UK doctors respond to a financial conflict of interest in treatment decisions. The reimbursement system for dispensing practices may generate unintended consequences. …”
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Enhanced interannual variability of the terrestrial carbon sink in China under high emissions by Han Wu, Li Zhang, Honglin He, Xiaoli Ren, Mengyu Zhang, Dingjin Chu, Yuanhao Zheng

“…Our results highlight the crucial influence of future fluctuations in monsoon climate systems on terrestrial carbon sink IAV and the urgency of reducing the uncertainties of Earth system models in predicting both climate in monsoon regions and the responses of carbon cycling processes to temperature.…”
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Bioenergetic Modeling of the Relationship Between Voltage and Electroactive Microbial Biomass Yield for Bioelectrochemical Carbon Dioxide Reduction to Methane by Vafa Ahmadi, Nabin Aryal

“…Optimal product synthesis in bioelectrochemical systems (BESs) requires a comprehensive understanding of the relationship between external voltage and microbial yield. …”
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Sources of right to freedom of peaceful assembly by М. А. Sambor

“…By far, the most widespread source of the right to freedom of peaceful assembly and with didactic features of knowing this right in the system of Ukrainian law is a legal act. The Constitution of Ukraine belongs to this type of sources of the right to freedom of peaceful assembly (as its special norms intended to regulate public relations in the exercise of the right to freedom of peaceful assembly in Ukrainian society, as well as general rules that ensure the ordering of relations and the formation of legal space for the implementation of the said rights), the Civil Code of Ukraine, the Code of Administrative Judiciary of Ukraine, as well as other procedural normative legal acts, which, although they do not contain any special rules, are directed to regulate relations precisely with the exercise of the right to freedom of peaceful assembly, but in their general form provide the opportunity to regulate a number of aspects of the exercise of the right to freedom of peaceful assembly. …”
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Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology by Andrés F. Londoño, Ajay Sharma, Jared Sealy, Vipin S. Rana, Shelby D. Foor, Vera Y. Matrosova, Elena K. Gaidamakova, Robert P. Volpe, Michael J. Daly, Brian M. Hoffman, Utpal Pal, J. Stephen Dumler

“…B. burgdorferi appears to have evolved a system not to protect from irradiation, but presumably to protect from oxidative stress when cyclically transmitted from tick to mammalian host and back. …”
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Neurological manifestations associated with COVID-19 vaccine by R. Alonso Castillo, J.C. Martínez Castrillo

“…The most frequently reported adverse events were Bell’s palsy 4936/13 809 (35.7%), headache (4067/13 809), cerebrovascular events 2412/13 809 (17.47%), Guillain-Barré syndrome 868/13 809 (6.28%), central nervous system demyelination 258/13 809 (1.86%) and functional neurological disorder 398/13 809 (2.88%). …”
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Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018 by Bouchez-Zacria, Malika, Calenge, Clément, Villers, Alexandre, Lecollinet, Sylvie, Gonzalez, Gaelle, Quintard, Benoit, Leclerc, Antoine, Baurier, Florence, Paty, Marie-Claire, Faure, Éva, Eraud, Cyril, Decors, Anouk

“…The responsiveness of such a network system could be improved by automating alerts.…”
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The Characteristics and Mortality of Osteoporosis, Osteomyelitis, or Rheumatoid Arthritis in the Diabetes Population: A Retrospective Study by Jin-Feng Huang, Qi-Nan Wu, Xuan-Qi Zheng, Xiao-Lei Sun, Chen-Yu Wu, Xiao-Bing Wang, Chen-Wei Wu, Bin Wang, Xiang-Yang Wang, Michael Bergman, Ai-Min Wu

“…We analyzed osteoporosis, osteomyelitis, and RA deaths associated with diabetes from 1999–2017 using the CDC WONDER system (CDC WONDER; https://wonder.cdc.gov). We used ICD-10 codes to categorize the underlying and contributing causes of death. …”
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CO2 field-flooding devices offer potential value for cardiopulmonary bypass procedures for CHD performed via a right-side small incision approach by Zhangke Guo, Zhimin Li, Song Bai, Feng Tong, Jia Zheng, Nan Ding, Xiaofeng Li

“…The use of such a CO2 field-flooding device at a flow rate of 5 L/min may help protect against cardiac and nervous system damage in children undergoing CHD surgery.…”
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Ações de conscientização sobre uso de repelentes e formas de combate ao mosquito Aedes aegypti by Denise de Abreu Garófalo, Anna Luiza Behling Pinto Chize, Luiz Eduardo Fileto Caldeira, Dalila dos Santos Cerqueira Pinto, Luciana Betzler de Oliveira de Siqueira, Ana Paula dos Santos Matos, Bárbara da Silva e Souza Lorca, Zaida Maria Faria de Freitas, Eduardo Ricci Júnior

“…In order to (i) inform adults and/or pregnant women and (ii) raise awareness among children and adolescents from the state school system about the correct use of repellents against diseases caused by Aedes aegypti, the research group composed of undergraduate and graduate students, professors and pharmacists of the University Pharmacy of the Federal University of Rio de Janeiro prepared information brochures and interactive games, in partnership with the UFRJ School of Fine Arts, and promoted lectures for adults and pregnant women in different public and private institutions around the city of Rio de Janeiro. …”
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Chromosome-level reference genome and annotation of the Arctic fish Anisarchus medius by Ruoyu Liu, Ziyu Meng, Yinan Mu, Ran Zhang, Hanhui Ma, Jingjing Hu, Yanan Wang, Yuxin Shi, Yanan Li, Chaofeng Wang, Weini Zhang, Longshan Lin, Ping Zheng, Xinhua Chen

“…Molecular pathway related to the endocrine system, carbohydrate metabolism, folding, sorting, and degradation, signal transduction, and transport and catabolism contribute to A. medius adaptation to extreme Arctic environments. …”
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Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment by Tatsuya Usui, Masashi Sakurai, Shuhei Enjoji, Hideyoshi Kawasaki, Koji Umata, Takashi Ohama, Nobuyuki Fujiwara, Ryotaro Yabe, Shunya Tsuji, Hideyuki Yamawaki, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Koichi Sato

“…However, ALI organoid culture system from tissues of colorectal cancer patients has not been established. …”
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