Amyloidogenic immunoglobulin light chains disturb contractile function and calcium transients in a human cardiac spheroid model of light chain (AL) amyloidosis by Mélanie Bézard, Jean-Sébastien Vartanian-Grimaldi, Julien Henri, Denisa Calin, Amira Zaroui, Mounira Kharoubi, Thibaud Damy, Onnik Agbulut, Ekaterini Kordeli

“…Abstract Light chain (AL) amyloidosis is a serious systemic disease caused by the deposition of free misfolded immunoglobulin light chains (LCs) in the form of amyloid fibrils within tissues. …”
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Construction and management of echelon talent of Integrated Chinese and Western Medicine nursing in general hospitals (综合性医院中西医结合护理人才梯队建设管理实践)... by TAN Lei (谭蕾), CUI Yuqian (崔玉倩), ZHANG Zhenyu (张振宇)

“…Objective To explore the construction and management of Traditional Chinese Medicine nursing team and talent training, improve the supervision system, establish a reasonable structure, professional, high quality of integrated traditional Chinese and western medicine nursing talent echelon, and then lead and promote the high-quality development of nursing work in the hospital. …”
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Implementasi Algoritma Catboost Dan Shapley Additive Explanations (SHAP) Dalam Memprediksi Popularitas Game Indie Pada Platform Steam by Mohammad Teddy Syamkalla, Siti Khomsah, Yohani Setya Rafika Nur

“…The existence of steam trading cards category, RPG genre and compatibility on mac operating system will increase the popularity. This also happens with the higher prices and achievements provided. …”
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Evaluation of the Therapeutic Effect of Traditional Chinese Medicine on Osteoarthritis: A Systematic Review and Meta-Analysis by Lin Wang, Xiao-Fei Zhang, Xue Zhang, Dong-Yan Guo, Yu-Wei Duan, Zhi-Chao Wang, Li-Shan Pei, Han Ru, Jiang-Xue Cheng, Ya-Jun Shi, Jun-Bo Zou

“…The quality evaluation included in the study was evaluated independently according to the Cochrane intervention system evaluation manual. In this meta-analysis, 68.18% of the literature correctly described the conditions for the generation of random assignment sequences, only 6.82% of the literature correctly mentioned the hidden details of allocation, and all studies mentioned randomly assigned participants. …”
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Is global health truly global? A hashtag analysis of #GlobalHealth disparities on X by Zara Arshad, Pranav Sharma, Shweta Sharma, Mustafa Sajjad Cheema, Mustafa Sajjad Cheema, Charu Agarwal, Charu Agarwal, Tamara Tango, Tamara Tango, Farhan Bin Matin, Atanas G. Atanasov, Atanas G. Atanasov, Atanas G. Atanasov, Bodrun Naher Siddiquea, Maima Matin, Olga Adamska, Artur Stolarczyk, Rahul Kashyap, Rahul Kashyap, Faisal A. Nawaz, Faisal A. Nawaz

“…The analysis was performed using Symplur Signals to assess several parameters, such as the cumulative number of posts, impressions, category of users, co-occurring hashtags, and geolocation. The Symplur Rank system was used to assess the impact of influencers using the hashtag.ResultsA total of 843,762 posts were shared by 150,408 X users, with 4,639,144,304 impressions. …”
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Numerical simulation of Stephan blowing impacts on thermally laminated 3D flow of MHD trihybrid nanofluid with Soret and Dufour effects by Noureddine Elboughdiri, Munawar Abbas, Hamdi Ayed, Abir Mouldi, Nahid Fatima, Dilsora Abduvalieva, Mohamed Said, Ibrahim Mahariq, Ahmed S. Hendy, Ahmed M. Galal

“…By accurately forecasting the behavior of nanofluids, the model aids in the optimization of thermal management in these systems, enhancing system dependability and energy efficiency. …”
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The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

“…The ArcAB two-component system includes a histidine kinase sensor (ArcB) and a regulator (ArcA) that respond to changes in cell oxygen availability. …”
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Incidence and temporal trends of out-of-hospital cardiac arrest in Shenzhen, China (2011–2018) by Hong Zhu, Junpeng Liu, Tianqi Yang, Yan Zhang, Yanjun Xu, Yunfeng Xu, Hao Wu, Li Li, Yufeng Luo, Cai Wen, Tao Yu

“…Low bystander intervention rated and prolonged response times contribute to poor outcome, underscoring the need for system improvements.…”
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Assessing the feasibility of measuring residents’ quality of life in English care homes and the construct validity and internal consistency of measures completed by staff proxy: a... by Claire Goodman, Julienne Meyer, Karen Spilsbury, Barbara Hanratty, Rachael Carroll, Adam L Gordon, Gizdem Akdur, Anne Killett, Jennifer Burton, Ann-Marie Towers, Stacey Rand, Nick Smith, Sinead Palmer, Stephen Allan, Lucy Anne Webster

“…All homes used a digital record system from one of two suppliers.Participants Data were extracted from 748 residents. …”
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Development of a core measurement set for research in degenerative cervical myelopathy: a study protocol (AO Spine RECODE-DCM CMS) by Robert Chen, Angus G K McNair, Vafa Rahimi-Movaghar, Julio C Furlan, Benjamin M Davies, Oliver D Mowforth, Iwan Sadler, Bizhan Aarabi, Brian K Kwon, Michael G Fehlings, James S Harrop, Armin Curt, Ellen Sarewitz, Carl Moritz Zipser, Timothy F Boerger, Mark R N Kotter, James Milligan, Lindsay Tetreault, Danyal Khan, Keng Siang Lee, Alvaro Yanez Touzet, Ricardo Rodrigues-Pinto, James D Guest, Sukhvinder Kalsi-Ryan, Shirley Widdop

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The Financial Implications of Pancreatic Surgery: The Hospital Is the Big Winner, Not the Surgeon! by Nitzan Zohar, MD, Avinoam Nevler, MD, Sean P. Maher, Matthew C. Rosenthal, Florence Williams, Wilbur B. Bowne, MD, FACS, Charles J. Yeo, MD, FACS, Harish Lavu, MD, FACS

“…Nevertheless, in the context of the current US health care system, the reimbursement to the surgeon in the form of professional fees is a relatively small fraction of the total health care receipts for these patients. …”
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KATALIKŲ BAŽNYČIOS KAITA LIETUVOJE TRANSFORMACIJŲ LAIKOTARPIU by Valdas Pruskus

“…If civic society is defined as system of various groups, societies, unions, the Church becomes one of many groups of interest. …”
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Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…We hypothesized that the presence of a secondary system for L-met production conferred by MetAB in W7 but not IA3902 might explain the difference in both chicken colonization and L-met availability. …”
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Whole-genome sequencing and phylogenetic analysis of Salmonella isolated from pullets through final raw product in the processing plant of a conventional broiler complex: a longitu... by Yagya Adhikari, Matthew A. Bailey, Steven Kitchens, Pankaj Gaonkar, Luis R. Munoz, Stuart B. Price, Dianna V. Bourassa, Laura Huber, Richard J. Buhr, Kenneth S. Macklin

“…Samples were screened with 3M Molecular Detection System and were further processed for the confirmation of results. …”
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Isomeric Differentiation of Four Triterpene Acids Using Full Collision Energy Ramp-MS2 Analysis by Li-juan WU, Rui-ru NAN, Qian WANG, Xin CHEN, Wen-jing LIU, Yue-lin SONG

“…These compounds, characterized by their ring system structures, can be further categorized into several subtypes, primarily tetracyclic and pentacyclic triterpenoid acids. …”
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Association of iron deposition in MS lesion with remyelination capacity using susceptibility source separation MRI by Hyeong-Geol Shin, Woojun Kim, Jung Hwan Lee, Hyun-soo Lee, Yoonho Nam, Jiwoong Kim, Xu Li, Peter C.M. van Zijl, Peter A. Calabresi, Jongho Lee, Jinhee Jang

“…Objectives: Susceptibility source-separation (χ-separation) MRI provides in-vivo proxy of myelin (diamagnetic susceptibility, χdia) and iron concentrations (paramagnetic susceptibility, χpara) in the central nervous system, potentially uncovering myelin- and iron-related pathology in multiple sclerosis (MS) lesions (e.g., demyelination, remyelination, and iron-laden microglia/macrophages formation). …”
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Trichoderma virens XZ11-1 producing siderophores inhibits the infection of Fusarium oxysporum and promotes plant growth in banana plants by Haiyang Cui, Qifeng Cheng, Tao Jing, Yufeng Chen, Xiaojuan Li, Miaoyi Zhang, Dengfeng Qi, Junting Feng, Farinaz Vafadar, Yongzan Wei, Kai Li, Yankun Zhao, Dengbo Zhou, Jianghui Xie

“…Pot experiments demonstrated that T. virens XZ11-1 could colonize in the root system of banana plants. The symbiotic interaction not only improve plant resistance to Foc TR4, but also enhance iron absorption of roots to promote plant growth by secreting siderophores. …”
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Real life outcome analysis of breast cancer brain metastases treated with Trastuzumab Deruxtecan by Alessandra Fabi, Alessandro Rossi, Roberta Caputo, Simona Pisegna, Simone Scagnoli, Francesco Pantano, Giuliana D’Auria, Palma Fedele, Agnese Fabbri, Claudio Vernieri, Michela Palleschi, Luisa Carbognin, Gianluigi Ferretti, Elena Di Monte, Ida Paris, Francesco Pavese, Ornella Garrone, Antonio Franco, Michelino De Laurentiis, Gianluca Franceschini, Giovanni Scambia, Diana Giannarelli, Riccardo Masetti, Andrea Botticelli

“…Abstract Tumor dissemination to the central nervous system (CNS) is almost a rule in the treatment journey of advanced HER2+ breast cancer (BC). …”
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An improved statistical bias correction method for Global Climate Model (GCM) precipitation projection: A case study on the CMCC-CM2-SR5 model projection in China’s Huaihe River Ba... by Yuning Luo, Ke Zhang, Wen Wang, Xinyu Chen, Jin Feng, Haijun Wang, Wei Liu, Cheng Guo, Cuiying Chen, Xiaozhong Wang

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A concept of natural genome reconstruction. Part 2. Effect of extracellular double-stranded DNA fragments on hematopoietic stem cells by V. S. Ruzanova, S. G. Oshikhmina, A. S. Proskurina, G. S. Ritter, S. S. Kirikovich, E. V. Levites, Y. R. Efremov, T. V. Karamysheva, M. I. Meschaninova, A. L. Mamaev, O. S. Taranov, A. S. Bogachev, S. V. Sidorov, S. D. Nikonov, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, E. V. Dolgova, S. S. Bogachev

“…A direct interaction of CD34 and CD84 (SLAMF5) glycoproteins, markers of hematopoietic stem cells, with double-stranded DNA fragments was demonstrated using an electrophoretic mobility shift assay system. In cells negative for CD34, which also internalize fragments, concatemerization of the fragments delivered into the cell occurs. …”
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