Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

“…Methods: Chemical composition of Coronil was determined by the Prominence-XR UHPLC system. The ELISA-based ACE2 binding inhibition assay was performed to delineate the effect of Coronil on the interaction between human ACE2 receptor and different Omicron variant S-proteins such as BA.4/BA5, XBB, BA.2.75.2, BA4.6/BF.7, BA.2.75.2, BQ.1.1 and a recently found spike protein variant JN.1 which is thought to emerge from BA.2.86. …”
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Immune Profile Differences between IgG4-Related Diseases and Primary Sjögren’s Syndrome by Qin Y, Shang L, Wang Y, Feng M, Liang Z, Wang N, Gao C, Luo J

“…Moreover, IgG4-RD patients with mouth and eye dryness had higher levels of B (p = 0.006), Th (p = 0.026), Th2 (p = 0.007), and Treg cells (p = 0.028) than IgG4-RD patients without mouth and eye dryness.Conclusion: Immune system disorder is an outstanding feature of IgG4-RD, and its feature differ from pSS. …”
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Gastric Cancer Cell Lines Have Different MYC-Regulated Expression Patterns but Share a Common Core of Altered Genes by Jersey Heitor da S. Maués, Helem Ferreira Ribeiro, Giovanny R. Pinto, Luana de Oliveira Lopes, Letícia M. Lamarão, Carla Mariana F. Pessoa, Caroline de Fátima Aquino Moreira-Nunes, Raimundo Miranda de Carvalho, Paulo P. Assumpção, Juan A. Rey, Rommel M. Rodríguez Burbano

“…When we analyzed our DEGs considering KEGG metabolic pathways, we found 12 common branches covering a wide range of biological functions, and three of them were common to all three cell lines: ubiquitin-mediated proteolysis, ribosomes, and system and epithelial cell signaling in Helicobacter pylori infection. …”
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Hubungan Konsumsi Makanan Sumber Antioksidan dan Omega-3 Terhadap Tekanan Darah Masyarakat di Sumatera Barat by Harris Putra Reza, Nur Indrawati Lipoeto, Husnil Kadri

“…</p><p><strong>Kata kunci:</strong> antioksidan, omega-3, tekanan darah</p><p> </p><p><strong><em>Abstract</em></strong><strong><em></em></strong></p><p>             <em>Blood pressure regulation involves many systems, one of the most important is endothelial system through nitric oxide activity. …”
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Protocol for process evaluation of SMART Mental Health cluster randomised control trial: an intervention for management of common mental disorders in India by Anushka Patel, David Peiris, Pallab K Maulik, Graham Thornicroft, Shekhar Saxena, Sudha Kallakuri, Amanpreet Kaur, Siddhardha Devarapalli, Mercian Daniel, Beverley M Essue, Shashi Kant, D Praveen, Usha Raman, Rajesh Sagar, Ankita Mukherjee

“…Systematic Medical Appraisal, Referral and Treatment (SMART) Mental Health integrates a community-level stigma reduction campaign and task sharing with the help of a mobile-enabled electronic decision support system (EDSS)—to reduce psychiatric morbidity due to stress, depression and self-harm in high-risk individuals. …”
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Neural Network and Hybrid Methods in Aircraft Modeling, Identification, and Control Problems by Gaurav Dhiman, Andrew Yu. Tiumentsev, Yury V. Tiumentsev

“…That is, it is required to solve also the identification problem for dynamical systems. We propose an approach to solving the above-mentioned problems based on artificial neural networks (ANNs) and hybrid technologies. …”
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SARS-CoV-2 transmission dynamics in Mozambique and Zimbabwe during the first 3 years of the pandemic by Roselyn F. Kaondera-Shava, Marta Galanti, Matteo Perini, Jiyeon Suh, Shannon M. Farley, Sergio Chicumbe, Ilesh Jani, Annette Cassy, Ivalda Macicame, Naisa Manafe, Wafaa El-Sadr, Jeffrey Shaman

“…Here, to better understand SARS-CoV-2 transmission dynamics in two southern African countries, Mozambique and Zimbabwe, we developed a dynamic model-Bayesian inference system to estimate key epidemiological parameters, namely the transmission and ascertainment rates. …”
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Quantitative Validation of Hematocrit Percentage Drop Cutoff Points in Postpartum Hemorrhage: An Automated Gravimetric Approach by Venance Basil Kway, José Enrique Calacuayo Rojas, Josué Sidonio Rodríguez Cuevas, Ursula Medina Moreno, José Sergio Camacho Juárez, Jorge Francisco Ayala González, Karla Krebs Larraga, Ilse Veronica Castro Martinez, Roberto Arturo Castillo Reyther, Antonio Gordillo Moscoso, Yang Pan

“…Blood loss was measured by an automated gravimetric system integrated into a suction blood collector and surgical gauze weighing systems to automatically sum up blood loss immediately after hysterectomy and fetal delivery. …”
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Feminization of Maroon Clownfish (<I>Amphiprion biaculeatus<I/>, Bloch 1790) with 17β-Estradiol Hormonal Induction by Helena Sahusilawane, Agus Oman Sudrajat, Muhmmad Agus Suprayudi, Dinar Tri Soelistyowati, Ligaya I. T. A. Tumbelaka, Irzal Effendi

“…Five fish composed of α-fish, β-fish, and three γ-fish were reared in each aquarium for 90 days with a flowing water system. The α- and β-fish were then removed, while the γ-fish was injected with hormone. …”
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Exploring multi-level factors determining social participation of students with intellectual disabilities in inclusive physical education classes by Christoffer Klenk, Matthias Buser

“…Discussion/Conclusion Assuming that not the SwID, but the education system has to adapt its structures for effective participation of all students, focus for enhancing SP for teacher training should be on class-related variables, in particular how to develop a positive class climate. …”
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Positively charged polysilsesquioxane/iodide lonic liquid as a quasi solid-state redox electrolyte for dye-sensitized photo electrochemical cells: infrared, <mml:math alttext="$^{{...

“…DSPEC cells based on a titania-dye system with MTMSPI<mml:math alttext="$^+I^-$"> <mml:mrow> <mml:msup> <mml:mi></mml:mi> <mml:mtext>+</mml:mtext> </mml:msup> <mml:msup> <mml:mtext>I</mml:mtext> <mml:mo>&#x2212;</mml:mo> </mml:msup> </mml:mrow> </mml:math> electrolyte containing iodine (0.1 M) reached an overall efficiency between 3.3&#8211;3.7%.…”
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Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study by Mingyi Zhao, Jingyi Diao, Peng Huang, Jinqi Li, Yihuan Li, Yang Yang, Liu Luo, Senmao Zhang, Letao Chen, Tingting Wang, Ping Zhu, Jiabi Qin

“…We collected the mothers’ information by questionnaire and detected children’s NKX2.5 variants with a MassARRAY system. The interaction coefficient (γ) was used to quantify the estimated gene-environment interactions. …”
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Implementation of prehospital point-of-care ultrasound using a novel continuous feedback approach in a UK helicopter emergency medical service by Salman Naeem, Shadman Aziz, Thomas Hirst, Johannes Strobel, Jamin M. Mulvey, Ailidh Lang, Jankee Patel, Alexander Smith, Ka Jun Cheng, Michael Palmer, Jonas Schlautmann, Michael D. Christian, Daniel Nevin

“…Conclusion Introduction of prehospital PoCUS in a HEM service utilizing high quality training, user-friendly workflow and image archiving system, robust governance framework and continuous feedback may be feasible allowing high quality ultrasound examinations. …”
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Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight by Yu Du, Bing Han, Katharina Biere, Nathalie Abdelmalek, Xinyu Shu, Chaoyang Song, Guangyao Chen, Ning Li, Marina Tuschen, Huan Wu, Shujin Sun, Alexander Choukér, Mian Long, Dominique Moser

“…To investigate the impact of partial gravity on immune cell attachment to vessel endothelia, THP-1 cells and HUVEC cell layers were monitored in a flow chamber system during parabolic flight in lunar (0.16 g) or Martian (0.38 g) gravity. …”
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Akkermansia muciniphila and its metabolite propionic acid maintains neuronal mitochondrial division and autophagy homeostasis during Alzheimer’s disease pathologic process via GPR4... by Zifan Wang, Cai Wang, Boyu Yuan, Li Liu, Haoming Zhang, Mingqiang Zhu, Hongxia Chai, Jie Peng, Yanhua Huang, Shuo Zhou, Juxiong Liu, Liyong Wu, Wei Wang

“…In addition, short-chain fatty acids (SCFA) produced by intestinal microbiota metabolism have been considered to be important factors affecting central nervous system (CNS) homeostasis. Among the main mediators of host-microbe interactions, volatile fatty acids play a crucial role. …”
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Anterior Controllable Antedisplacement and Fusion (ACAF) for Cervical Stenosis Patients With Hyperextension Injury: A Retrospective Study by Shuangxi Sun, Yingying Miao, Tao Xu, Kaiqiang Sun, Yijuan Lu, Jingchuan Sun, Jiuyi Sun, Jiangang Shi

“…Neurological function was assessed using the American Spinal Injury Association (ASIA) grading system and Japanese Orthopaedic Association (JOA) score. …”
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Modeling the determinants of attrition in a two-stage epilepsy prevalence survey in Nairobi using machine learning by Daniel M. Mwanga, Isaac C. Kipchirchir, George O. Muhua, Charles R. Newton, Damazo T. Kadengye, Abankwah Junior, Albert Akpalu, Arjune Sen, Bruno Mmbando, Charles R. Newton, Cynthia Sottie, Dan Bhwana, Daniel Mtai Mwanga, Damazo T. Kadengye, Daniel Nana Yaw, David McDaid, Dorcas Muli, Emmanuel Darkwa, Frederick Murunga Wekesah, Gershim Asiki, Gergana Manolova, Guillaume Pages, Helen Cross, Henrika Kimambo, Isolide S. Massawe, Josemir W. Sander, Mary Bitta, Mercy Atieno, Neerja Chowdhary, Patrick Adjei, Peter O. Otieno, Ryan Wagner, Richard Walker, Sabina Asiamah, Samuel Iddi, Simone Grassi, Sloan Mahone, Sonia Vallentin, Stella Waruingi, Symon Kariuki, Tarun Dua, Thomas Kwasa, Timothy Denison, Tony Godi, Vivian Mushi, William Matuja

“…Methods: All individuals in the Nairobi Urban Health and Demographic Surveillance System (NUHDSS) (Korogocho and Viwandani) were screened for epilepsy in two stages. …”
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Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model by Zigui Chen, Chunyuan Zhang, Yuhua Fang, He Zhang, Jiawei Luo, Changfeng Miao, Jiale Li, Jun Peng, Yingqi Qiu, Ying Xia, Qisheng Luo

“…Meanwhile, OM-MSCsNrf2 inhibited the levels of pro-inflammatory genes and affected the glycolysis in PC12 cells. In the co-cultured system of OM-MSCsNrf2 and BV2 cells, M2 microglial polarization was observed, and the levels of M2 microglia-relevant genes and the phosphorylation of STAT6/AMPKα/SMAD3 were elevated. …”
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Spatial analysis of measles cases and vaccination coverage in the Somali region, eastern Ethiopia by Abdilahi Ibrahim Muse, Abdilahi Ibrahim Muse, Mahdi Yonis Kayat, Mohamed Harir Aden, Jemal Beksisa Shuramu, Shikur Mohammed, Musse Ahmed Ibrahim, Musse Ahmed Ibrahim, Binyam Mohammedbirhan Berhe, Ahmed Abdi Kalinle, Sahardiid Ali Abdilahi

“…It can be prevented by two doses of the measles vaccine, either alone or in combination with measles-rubella (MR), which is a low-cost strategy for lowering morbidity and mortality among children.ObjectivesTo conduct spatial analysis of measles cases and vaccination coverage in the Somali region, Eastern Ethiopia.MethodsThis retrospective study was done by using public health emergency directorate measles data from 2022 to 2023 and four years (July 2019–July 2023) of vaccination data from district health information system version 2.36. After the data completeness and consistency were ensured, it was cleaned and recoded. …”
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Role of calcium overload-mediated disruption of mitochondrial dynamics in offspring neurotoxicity due to methylmercury exposure during pregnancy and lactation by Lingxu Kong, Huajie Yang, Jing Yang, Liujiangshan Jiang, Bin Xu, Tianyao Yang, Wei Liu

“…MeHg crosses the placental barrier and accumulates in the brain of the fetus, affecting the growth and development of the central nervous system. Although it has been demonstrated that MeHg induces neuronal calcium overload in the rat cerebral cortex, the role of calcium overload in MeHg-induced neurodevelopmental toxicity remains unclear. …”
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