Regulatory T Cell Phenotype Related to Cytokine Expression Patterns in Post‐COVID‐19 Pulmonary Fibrosis and Idiopathic Pulmonary Fibrosis by Sara Gangi, Laura Bergantini, Irene Paggi, Marco Spalletti, Paolo Cameli, Elena Bargagli, Miriana d'Alessandro

“…High cytokine values showed a pro‐fibrotic environment in PCLF patients, suggesting dysregulation of the immune system of these patients. Moreover, the immunological similarity between IPF and PCLF patients suggests that SARS‐CoV2 infection may trigger the activation of biological pathways common with IPF.…”
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The application of Vavilov’s approaches to the phylogeny and evolution of cultivated species of the genus <i>Avena</i> L. by I. G. Loskutov, A. A. Gnutikov, E. V. Blinova, A. V. Rodionov

“…The theoretical basis of this concept consisted of the law of homologous series in variation, research on the problem of species as a system, botanical and geographical bases of plant breeding, and the key theory of the centers of origin of cultivated plants. …”
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hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling by Mengbo Yang, Xinda Chen, Ming Zhang, Xiaolin Zhang, Dongdong Xiao, Huiming Xu, Mujun Lu

“…In vitro, CCSMCs underwent hypoxia and were then co-cultured with ADSC or hUC-MSC using a transwell system. The mitochondrial mass and function, as well as signaling pathways, were investigated. …”
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Exploring the assessment of post-cardiac valve surgery pulmonary complication risks through the integration of wearable continuous physiological and clinical data by Lixuan Li, Yuekong Hu, Zhicheng Yang, Zeruxin Luo, Jiachen Wang, Wenqing Wang, Xiaoli Liu, Yuqiang Wang, Yong Fan, Pengming Yu, Zhengbo Zhang

“…We examined 100 cardiac valvular surgery patients, where wearable technology was utilized to collect and analyze nocturnal physiological data at the 24-hour admission, in conjunction with clinical data extraction from the Hospital Information System’s electronic records. We systematically evaluated three different input types (physiological, clinical, and both) and five classifiers (XGB, LR, RF, SVM, KNN) to identify the combination with strong predictive performance for PPCs. …”
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Benchmarking the identification of a single degraded protein to explore optimal search strategies for ancient proteins by Rodriguez Palomo, Ismael, Nair, Bharath, Chiang, Yun, Dekker, Joannes, Dartigues, Benjamin, Mackie, Meaghan, Evans, Miranda, Macleod, Ruairidh, Olsen, Jesper V., Collins, Matthew J.

“…We systematically investigated the performance of a wide range of sequencing tools and search engines in a controlled system: the experimental degradation of the single purified bovine β-lactoglobulin (BLG), heated at 95°C and pH 7 for 0, 4 and 128 days. …”
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Development and validation of a novel artificial intelligence algorithm for precise prediction the postoperative prognosis of esophageal squamous cell carcinoma by Zichen Wang, Zhihan Xiao, Tongyu Zhang, Meiyou Lu, Hai Li, Jing Cao, Jianan Zheng, Yichan Zhou, Juncheng Dai, Cheng Wang, Liang Chen, Jing Xu

“…The purpose of this study is to develop a novel clinically prognostic prediction system to facilitate the individualized postoperative care. …”
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Resensitizing β‐Lactams by Reprogramming Purine Metabolism in Small Colony Variant for Osteomyelitis Treatment by Tingwang Shi, Qiong Wu, Zesong Ruan, Zhiyuan Luo, Wenbo Wang, Zhao Guo, Yihong Ma, Xin Wang, Guangyu Chu, Han Lin, Min Ge, Yunfeng Chen

“…Therefore, a co‐delivery system for lonidamine and oxacillin is constructed with amino‐modified dendritic mesoporous silica as a carrier, which showed high efficacy and safety in combating SCV both in vitro and in vivo experiments. …”
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Microwave Ablation of T1a and T1b Renal Masses: A Retrospective Study by Assim Saad Eddin, Karan Rao, Bradford Oliva, Ajmain Chowdhury, Shetty Zubin, Chad Tracy, Brian J. Smith, Sandeep T. Laroia

“…The Solero microwave tissue ablation system (Angiodynamics, Latham, NY, United States) was utilized. …”
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Inflammatory Indices and MAFLD Prevalence in Hypertensive Patients: A Large-Scale Cross-Sectional Analysis from China by Shen D, Cai X, Hu J, Song S, Zhu Q, Ma H, Zhang Y, Ma R, Zhou P, Yang W, Hong J, Zhang D, Li N

“…Complete blood counts were used to calculate inflammatory indices, including the monocyte-to-lymphocyte ratio (MLR), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic inflammatory response index (SIRI), systemic immune-inflammation index (SII), and aggregate index of systemic inflammation (AISI). …”
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Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles by Kowichi Jimbow, Yasue Ishii-Osai, Shosuke Ito, Yasuaki Tamura, Akira Ito, Akihiro Yoneta, Takafumi Kamiya, Toshiharu Yamashita, Hiroyuki Honda, Kazumasa Wakamatsu, Katsutoshi Murase, Satoshi Nohara, Eiichi Nakayama, Takeo Hasegawa, Itsuo Yamamoto, Takeshi Kobayashi

“…During these therapeutic processes, NPrCAP was also expected to provide melanoma-targeted drug delivery system.…”
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La transformation de l’ancien centre de détention secrète de Derb Moulay Cherif en musée des « années de plomb » (Casablanca, Maroc) by Anissa Habane

“…For several decades, this secret site, the centerpiece of the repressive system, held, tortured and killed political activists, union members and student activists, as well as random individuals. …”
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Advances and applications on non-Hermitian topological photonics by Yan Qiuchen, Zhao Boheng, Zhou Rong, Ma Rui, Lyu Qinghong, Chu Saisai, Hu Xiaoyong, Gong Qihuang

“…On one hand, photonics system can introduce artificially-constructed gain and loss to study non-Hermitian physics. …”
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Lactic acid in the vaginal milieu modulates the Candida-host interaction by Diletta Rosati, Marisa Valentine, Mariolina Bruno, Arnab Pradhan, Axel Dietschmann, Martin Jaeger, Ian Leaves, Frank L. van de Veerdonk, Leo A.B. Joosten, Sumita Roy, Mark H. T. Stappers, Neil A.R. Gow, Bernhard Hube, Alistair J.P. Brown, Mark S. Gresnigt, Mihai G. Netea

“…We examined how lactic acid abundance in the vaginal niche impacts the interaction between C. albicans and the human immune system using an in vitro culture in vaginal simulative medium (VSM). …”
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Corrosion behavior of Fe amorphous/Al-12Si piston composites with core-shell structure by Yingdong Wang, Zuxiang Lin, Chengzhou Liu, Deyong Zhao, Chunqiong Li, Yuan Wang

“…Abstract The current piston material, Al-12Si, lacks sufficient passivation in the acidic lubrication system of biodiesel engines, making it prone to corrosion in the presence of Cl−. …”
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Polish Historiography of Polish - Lithuanian Union of 20th Century by Mečislovas Jučas

“…They found functions of Lithuanian statehood, at first the existence of the separate state institutions: chancellor, marshal, treasury, and army; also law, court system, Lithuanian parliamentarism. They considered, however, the reforms of the end of the 17th century as an abolishment of Lithuanian statehood. …”
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Blended digital health intervention for adolescents at high risk with digital media use disorders: protocol for a randomised controlled trial within the Res@t-Consortium by Oliver Labrenz, Oliver Labrenz, Lucie Waedel, Lucie Waedel, Michael Kölch, Michael Kölch, Susanne Lezius, Christina Wacker, Antonia Fröhlich, Antonia Fröhlich, Kerstin Paschke, Rainer Thomasius, Olaf Reis, Olaf Reis

“…In particular, children and adolescents who live in families that are part of the child and youth welfare system and receive support services are considered to be at high risk of developing mental disorders. …”
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Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022 by Rebecca F. Wilson, Xin Yue, Karen E. Thomas, Krishna Kiran Kota, Carter J. Betz

“…Participants and methods: This study integrated National Violent Death Reporting System (NVDRS) data, county poverty data, and population estimates data. …”
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Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening by Wei Jin, Yexuan Deng, John E. La Marca, Emily J. Lelliott, Sarah T. Diepstraten, Christina König, Lin Tai, Valentina Snetkova, Kristel M. Dorighi, Luke Hoberecht, Millicent G. Hedditch, Lauren Whelan, Geraldine Healey, Dan Fayle, Kieran Lau, Margaret A. Potts, Moore Z. Chen, Angus P. R. Johnston, Yang Liao, Wei Shi, Andrew J. Kueh, Benjamin Haley, Jean-Philippe Fortin, Marco J. Herold

“…We further demonstrate successful in vivo gene editing, using normal and cancer-prone enAsCas12a stem cells to reconstitute the haematopoietic system of wild-type mice. We also present compact, genome-wide Cas12a knockout libraries, with four crRNAs per gene encoded across one (Scherzo) or two (Menuetto) vectors, and demonstrate the utility of these libraries across methodologies: in vitro enrichment and drop-out screening in lymphoma cells and immortalised fibroblasts, respectively, and in vivo screens to identify lymphoma-driving events. …”
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3D-AttenNet model can predict clinically significant prostate cancer in PI-RADS category 3 patients: a retrospective multicenter study by Jie Bao, Litao Zhao, Xiaomeng Qiao, Zhenkai Li, Yanting Ji, Yueting Su, Libiao Ji, Junkang Shen, Jiangang Liu, Jie Tian, Ximing Wang, Hailin Shen, Chunhong Hu

“…Abstract Purposes The presence of clinically significant prostate cancer (csPCa) is equivocal for patients with prostate imaging reporting and data system (PI-RADS) category 3. We aim to develop deep learning models for re-stratify risks in PI-RADS category 3 patients. …”
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Experimental Investigation of the Dependence of Accessible Porosity and Methane Sorption Capacity of Carbonaceous Shales on Particle Size by Garri Gaus, Anton Kalmykov, Bernhard M. Krooss, Reinhard Fink

“…Poor interconnectivity of the pore system and slow, diffusion-controlled transport will massively retard gas production. …”
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