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39681
Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2
Published 2025-01-01“…Function enrichment analyses revealed that the FRGs were mainly associated with responses to chemical stress and cytokine signaling in the immune system. Protein–protein interaction network analyses identified 8 hub FRGs including EZH2, EGFR, HIF1A, IL6, PTGS2, MAPK1, IL1B and SRC. …”
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39682
Evaluation of the efficacy of a novel lumbar exoskeleton with multiple interventions for patients with lumbar disc herniation: a multicenter randomized controlled trial of non-infe...
Published 2025-01-01“…The development of portable lumbar exoskeleton devices offers a new approach, combining traction, range of motion (ROM) exercises, and resistance training in a single system, potentially reducing treatment complexity and enhancing LDH patient outcomes.ObjectiveThis study aims to evaluate the efficacy and safety of a novel lumbar exoskeleton device compared to traditional traction methods combined with rehabilitation therapy for patients with LDH.MethodsA multicenter, non-inferiority randomized controlled trial was conducted with 118 participants diagnosed with LDH. …”
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39683
Transcription factors MhyFIL1 and MhyFIL3 <i>(Monotropa hypopitys)</i> determine the asymmetric development of above-ground lateral organs in plants
Published 2019-07-01“…Also, changes in the architecture of the aerial part and the root system of transgenic plants, including aberrant phyllotaxis and arrest of the shoot and root apical meristem development, were noted. …”
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39684
Systematic underestimation of type-specific ecosystem process variability in the Community Land Model v5 over Europe
Published 2025-01-01“…</p> <p>Here, we evaluated CLM5's predictions of water and energy fluxes using observations from eddy covariance stations from the Integrated Carbon Observation System (ICOS), remote sensing, and reanalysis data sets. …”
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39685
Radioprotective effects of polysaccharides from Poria cocos peels against 60Co-γ induced oxidative damage in vitro and in vivo
Published 2025-11-01“…Animal experiment results showed that PCPP could effectively reduce IR-induced oxidative damage of spleens and livers in mice, and alleviate the damage to the hematopoietic system. Furthermore, PCPP could greatly increase the activity of superoxide dismutase (SOD) and the content of glutathione (GSH) in serum, livers and spleens of 60Co-γ induced mice, and correspondingly reduce the accumulation of malondialdehyde (MDA), along with the prominent reduction of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum and livers in mice. …”
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39686
Dietary rosemary oil with/without zymogen forte improves water quality, growth hormones, immune-physiological response, stress resilience, and health status of Chelon ramada grown...
Published 2025-01-01“…In addition, there were significant enhancements observed in the levels of innate immune markers, such as white blood cells, total protein, albumin, and immunoglobulin. The complement system, specifically complement 3 and complement 4, also showed considerable improvements. …”
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39687
One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS
Published 2018-01-01“…The Agilent G6410A triple quadrupole liquid chromatography-mass spectrometry system was operated under the multiple reaction monitoring mode with an electrospray ionization in the positive mode. …”
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39688
Spatial and Temporal Variations in 94-GHz Radar Backscatter From a Springtime Snowpack
Published 2025-01-01“…AVTIS2 is a tripod-mounted, real-aperture radar system which mechanically scans across a scene of interest to map normalized radar cross section <inline-formula><tex-math notation="LaTeX">$(\sigma ^{0})$</tex-math></inline-formula> and 3-D point clouds. …”
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39689
Increased dicentric chromosome in peripheral lymphocytes is related to acute skin toxicity induced by radiotherapy in cancer patients
Published 2025-02-01“…Dicentric chromosomes were searched automatically using a high-throughput chromosome analysis system and were then confirmed manually. Finally, the relationships of the frequency of dicentric chromosomes (also referred to as the dic frequency) with acute skin and marrow toxicities were assessed. …”
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39690
A bioinformatic search for correspondence between differentially expressed genes of domestic versus wild animals and orthologous human genes altering reproductive potential
Published 2022-03-01“…Belyaev’s discovery of destabilizing selection during the domestication of animals and that this selection affects only gene expression regulation (not gene structure) and influences systems of neuroendocrine control of ontogenesis in a stressful environment. …”
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39691
Development of single-pin, un-barbed, pole-tagging of free-swimming dolphins and sharks with satellite-linked transmitters
Published 2024-04-01“…The latter showed very short touch/response intervals and highlighted the need for several iterative revisions of the pneumatic system. This resulted in reducing the total time from triggering to tag application to ~ 20 ms. …”
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39692
Thymus ad astra, or spaceflight-induced thymic involution
Published 2025-01-01“…Among the most vulnerable organs is the thymus, a cornerstone of immune system functionality, tasked with generating naive T cells essential for adaptive immunity. …”
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39693
Concentration of traffic air pollutants and influencing metrological factors in Hawassa City roadways, Ethiopia
Published 2025-01-01“…This study aimed to determine the concentration levels and spatial and temporal variations of traffic air pollutants in Hawassa and to investigate the influence of metrological parameters on the concentration of traffic air pollutants.MethodsA real-time monitoring system of Aero-Qual Series 300/500 was used to monitor pollutants, and 24 monitoring sites were included on both heavy and low-traffic volume roads. …”
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39694
Peningkatan Efisiensi Waktu Seleksi Karyawan dengan Kombinasi Metode Analytical Hierarchy Process dan Simple Additive Weighting
Published 2023-07-01“…Therefore, this research aims to produce a Decision Support System (DSS) that can present appropriate recommendations in selecting the best prospective employees using Analytical Hierarchy Process (AHP) and Simple Additive Weighting (SAW) methods with a faster and more efficient time. …”
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39695
Tumor aggression-defense index–a novel indicator to predicts recurrence and survival in stage II-III colorectal cancer
Published 2025-01-01“…Abstract Background Although the TNM staging system plays a critical role in guiding adjuvant chemotherapy for colorectal cancer (CRC), its precision for risk stratification in stage II and III CRC patients with proficient DNA mismatch repair (pMMR) remains limited. …”
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39696
The Role of Prenatal Exposure to Lead and Manganese in Child Cognitive Neurodevelopment at 18 Months: The Results of the Italian PHIME Cohort
Published 2025-01-01“…Prenatal lead (Pb) and manganese (Mn) exposure can impair neurodevelopment, targeting the central nervous system. This study investigated the effects of prenatal exposure to Pb and Mn on neurodevelopment in children at 18 months of age, using data from 607 Italian mother–child pairs enrolled in the Northern Adriatic Cohort II (NAC-II). …”
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39697
Assessing the determinants of out-of-pocket health expenditures among Cambodian households in informal employment using survey data
Published 2025-01-01“…Strategically engaging with private providers and pharmacies to improve access to essential services and medicines, coupled with the implementation of an effective referral system are important policy considerations to this end. …”
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39698
Pengembangan Aplikasi Berlatih Membaca Cepat Berbahasa Inggris Berbasis Progressive Web App dengan Metode Prototyping
Published 2024-10-01“…Hasil pengujian kepuasan pengguna melalui pengukuran System Usability Scale (SUS) mencapai nilai 84 dengan kategori grade B dan tergolong acceptable. …”
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39699
Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells
Published 2017-01-01“…Analogues able to inhibit NF-κB/DNA interaction at lower concentration than TMA were found and selected to investigate their biological activity on IB3-1 cells induced with TNF-α. In this biological system, NF-κB-mediated IL-8 gene expression was investigated. …”
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39700
Lidar estimates of birch pollen number, mass, and CCN-related concentrations
Published 2025-02-01“…In turn, this demonstrates the potential of ground-based lidars such as a ceilometer network with the polarization capacity to document large-scale birch pollen outbursts in detail and thus to provide valuable information for climate, cloud, and air quality modeling efforts, elucidating the role of pollen within the atmospheric system.</p>…”
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