Multiplex Bead Array Assay for Detection of 25 Soluble Cytokines in Blister Fluid of Patients with Complex Regional Pain Syndrome Type 1 by Claudia Heijmans-Antonissen, Feikje Wesseldijk, Renate JM Munnikes, Frank JPM Huygen, Patrick van der Meijden, Wim C. J. Hop, Herbert Hooijkaas, Freek J. Zijlstra

“…Multiplex bead array assays are useful systems to establish the involvement of cytokines in inflammatory processes by measurements in blister fluids of CRPS1. …”
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Process Optimization and Antioxidant Activity Analysis of White Kidney Bean Polypeptides Prepared by Composite Strain Fermentation by Sinan LI, Meng WANG, Yu AN, Qing WANG, Kaiyuan XU, Jia WANG, Zhihui ZHANG, Xi WANG, Ying WANG, Lu ZHANG

“…The changes in antioxidant activity of WKBPs after gastrointestinal digestion were evaluated in combination with the simulated digestive system in vitro. The results showed that the yield of WKBPs was 63.47% under the conditions of fermentation time 48 h, temperature 37 ℃, inoculation amount 9% and the ratio of Aspergillus aspergillus and Bacillus subtilis 1:1. …”
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Parastomal hernia repair: A 10-year retrospective study at District General Hospital—Recurrence and complications by Ali Javaid, Karim Muhammad, Nafees Qureshi

“…MATERIALS AND METHODS: This study involved retrospective continuous data collection of all patients coded as having PSH repair on the electronic patients’ record system over a period of 10 years from January 2011 till December 2020 at our District General Hospital. …”
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Fossil and Non-fossil Fuel Sources of Organic and Elemental Carbonaceous Aerosol in Beijing, Shanghai, and Guangzhou: Seasonal Carbon Source Variation by Di Liu, Matthias Vonwiller, Jun Li, Junwen Liu, Sönke Szidat, Yanlin Zhang, Chongguo Tian, Yinjun Chen, Zhineng Cheng, Guangcai Zhong, Pingqing Fu, Gan Zhang

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48-Week Outcome after Cessation of Nucleos(t)ide Analogue Treatment in Chronic Hepatitis B Patient and the Associated Factors with Relapse by Wen-xiong Xu, Qian Zhang, Xiang Zhu, Chao-shuang Lin, You-ming Chen, Hong Deng, Yong-yu Mei, Zhi-xin Zhao, Dong-ying Xie, Zhi-liang Gao, Chan Xie, Liang Peng

“…The study was submitted to ClinicalTrials.gov Protocol Registration and Results System with the assigned NCT ID NCT02883647.…”
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Mineralized Granitic Porphyry of the Yangla Copper Deposit, Western Yunnan, China: Geochemistry of Fluid Inclusions and H-O, S, and Pb Isotopes by Xinfu Wang, Bo Li, ShenJin Guan, Olivier Nadeau, Guo Tang

“…It is demonstrated that the evolution of ore-forming fluid is continuous from the skarn ore body (SOB) stage to the porphyritic ore body stage and belong to the products of the same ore-forming fluid system, and the unisothermal mixing and cooling actions were maybe the main mechanism at the metallic minerals precipitation in mineralized granitic porphyry (MGP). …”
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Protocol for the implementation evaluation of an integrated paediatric and primary care model: Strengthening Care for Children (SC4C) by Yvonne Zurynski, Susan Woolfenden, Peter D Hibbert, Harriet Hiscock, Raghu Lingam, Karen Wheeler, Michael Hodgins, Jade Burley, Rachel Pelly, Jane Le, Sonia Khano, Tammy Meyers Morris, Stephanie Germano

“…We will quantify implementation effectiveness in each general practice clinic using the CFIR validated scoring system. Importantly, we have embedded data collection post intervention to enable assessment of the sustainable adoption of the intervention. …”
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The association between the dietary inflammatory index and multiple myeloma: a case–control study by Hoda Zahedi, Mohammad-Reza Jowshan, Hamid Rasekhi, Maryam Amini, Omid Sadeghi, Mahshid Mehdizadeh, Sayeh Parkhideh, Moloud Payab, Erfan Zamani, Mahdi Shadnoush, Abbas Hajifathali

“…Abstract The dietary inflammatory index (DII) is a common grading system for diet inflammatory potential. Recent investigations link DII to hematopoietic malignancies. …”
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Cell-specific transcriptional signatures of vascular cells in Alzheimer’s disease: perspectives, pathways, and therapeutic directions by Soumilee Chaudhuri, Minyoung Cho, Julia C. Stumpff, Paula J. Bice, Özkan İş, Nilüfer Ertekin-Taner, Andrew J. Saykin, Kwangsik Nho

“…Abbreviations: AD, Alzheimer's disease; NVU, Neurovascular unit; CNS, Central Nervous System.…”
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Transformasi Lontar Babad Lombok Menuju Digitalisasi Berbasis Natural Gradient Flexible (NGF) by Muhammad Tajuddin Anwar, Syahroni Hidayat, Ahmat Adil

“…The aim of this study is to improve the quality of the digitized images before they fed into the database and information system that has been built. The enhanced image quality was measured, MSE and PSNR methods were used to measure the similarity level, and the Entropy and SSIM method were used to measure the information and visual perspective. …”
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Among various such strategies, the rapamycin-inducible dimerisable Cre (DiCre) recombinase system emerged as a powerful approach for conditional editing of essential genes in human-infecting P. falciparum and in the rodent malaria model parasite P. berghei. …”
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Systematic Review of Surgical Care in the Incarcerated Population: Identifying Knowledge Gaps for Future Research by Totadri Dhimal, MD, Paula Cupertino, PhD, Aqsa Ghaffar, BS, Yue Li, PhD, Xueya Cai, PhD, Cristopher Soto, BS, Megha Ramaswamy, PhD, MPH, Bruce W. Herdman, PhD, Fergal J. Fleming, MD, MPH, Anthony Loria, MD, MSCI

“…Background:. The US prison system detains around 2 million individuals, mainly young, indigent males from ethnic and racial minorities. …”
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Major Depressive Disorder as a Condition Negatively Impacting Both Mental and Physical Functioning. What to Do When There Is Treatment Resistance? by Monika Makar, Daria Michałka, Zuzanna Gałuszka, Natalie Papachristoforou, Justyna Głowacka, Aleksandra Kocjan, Emilia Bąk, Natalia Tekiela, Radosław Chmiel, Tomasz Bartuś

“…These include the absence of a standardized definition and grading system, which impedes the comparison of research outcomes. …”
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ASPECTOS PSICOJURÍDICOS DA SÍNDROME ALCOÓLICA FETAL by Eduardo Jorge Sant'Ana Honorato, Dalila Azevedo da Silva, Eunice Braga Borges dos Santos, Alice Sobral, Daniel Cerdeira de Sousa

“…SAF is a disease for which no cure but is completely preventable by withdrawal of alcohol intake during the gestation period when the nervous system is the formation and development process. At that point the family emerges as a protective factor because prevention can start at home with the family where the pregnant women they can be safer, with family watching and meeting their potentialities development needs is also in this context that the psychologist It presents with with its good practice, serving as a link connection between families and public policies to define strategies of integration and inclusion in society and interaction with other professionals. …”
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From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases by Qing Zhao, Linxin Wei, Youxin Chen

“…The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) has emerged as a promising tool for treating ocular diseases through gene editing and expression regulation. This system has contributed to the development of representative disease models, including animal models, organoids, and cell lines, thereby facilitating investigations into the pathogenesis of disease-related genes. …”
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Vaccination with Delta-PGM in the control of buffalo (Bubalus bubalis) brucellosis by Alfredo Sánchez-Villalobos, Leandro Salas, Hengelbert Fuenmayor, Omaira Contreras, Enmanuel Machado

“…In October 2022, diagnostic evaluation was carried out in 1,340 replacement females from this system, vaccinated or not, and divided into four groups according to body weight (G1: less than 170 k; G2: between 171 and 220; G3: from 221 to 270; G4: above 270 k). …”
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Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV by Michaela Helble, Michaela Helble, Xizhou Zhu, Pratik S. Bhojnagarwala, Kevin Liaw, Yangcheng Gao, Amber Kim, Kelly Bayruns, Madison E. McCanna, Joyce Park, Kylie M. Konrath, Kylie M. Konrath, Sam Garfinkle, Sam Garfinkle, Taylor Brysgel, David B. Weiner, David B. Weiner, Daniel W. Kulp, Daniel W. Kulp

“…As such, there is an urgent need to develop effective therapeutic vaccines to drive the immune system’s cellular response against cancer cells. One of the primary goals of cancer vaccination is to increase the potency and diversity of anti-tumor T-cell responses; one strategy to do so involves the delivery of full-length cancer antigens scaffolded onto DNA-launched nanoparticles to improve T-cell priming. …”
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Mucosal Immunization with an Influenza Vector Carrying SARS-CoV-2 N Protein Protects Naïve Mice and Prevents Disease Enhancement in Seropositive Th2-Prone Mice by Mariia V. Sergeeva, Kirill Vasilev, Ekaterina Romanovskaya-Romanko, Nikita Yolshin, Anastasia Pulkina, Daria Shamakova, Anna-Polina Shurygina, Arman Muzhikyan, Dmitry Lioznov, Marina Stukova

“…<b>Background/Objectives:</b> Intranasal vaccination enhances protection against respiratory viruses by providing stimuli to the immune system at the primary site of infection, promoting a balanced and effective response. …”
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Trisomy 21 screening with αlpha software and the Fetal Medicine Foundation algorithm by L Pistorius, C A Cluver, I Bhorat, L Geerts

“…To determine the screen positive and detection rates of prenatal screening for trisomy 21 in the SA private healthcare system. Methods. Data from the three largest laboratories collected between 2010 and 2015 were linked with genetic tests to assess screen positive and detection rates. …”
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Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

“…BackgroundEnhancing an organism’s survival hinges on the development of balanced and adaptable stress response systems. While the initial stress-response set-points in the hypothalamus may be genetically determined, they are further influenced by epigenetic factors during embryonic development. …”
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