miR-223 and Chromogranin A Affect Inflammatory Immune Cell Activation in Liver Metastasis of Neuroendocrine Neoplasms by Lukas Geisler, Katharina Detjen, Teresa Hellberg, Marlene Kohlhepp, Carsten Grötzinger, Jana Knorr, Ines Eichhorn, Raphael Mohr, Theresa Holtmann, Bertram Wiedenmann, Frank Tacke, Christoph Roderburg, Alexander Wree

“…Secretion/posttranslational proteolytic cleavage of CgA results in multiple bioactive fragments, which are essential regulators of the cardiovascular and immune system. miR-223, regulator of Nrlp3 inflammasome and neutrophil activation, was recently found to have decreased in patients with NEN. …”
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Single Exposure to Low-Intensity Focused Ultrasound Causes Biphasic Opening of the Blood-Brain Barrier Through Secondary Mechanisms by Tasneem A. Arsiwala, Kathryn E. Blethen, Cullen P. Wolford, Geoffrey L. Pecar, Dhruvi M. Panchal, Brooke N. Kielkowski, Peng Wang, Manish Ranjan, Jeffrey S. Carpenter, Victor Finomore, Ali Rezai, Paul R. Lockman

“…Low-intensity focused ultrasound (LiFUS), paired with microbubbles is a promising, non-invasive technique for transiently opening the BBB, allowing enhanced drug delivery to the central nervous system (CNS). However, the downstream physiological effects following BBB opening, particularly secondary responses, are not well understood. …”
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Machine Learning–Based Risk Factor Analysis and Prediction Model Construction for the Occurrence of Chronic Heart Failure: Health Ecologic Study by Qian Xu, Xue Cai, Ruicong Yu, Yueyue Zheng, Guanjie Chen, Hui Sun, Tianyun Gao, Cuirong Xu, Jing Sun

“… BackgroundChronic heart failure (CHF) is a serious threat to human health, with high morbidity and mortality rates, imposing a heavy burden on the health care system and society. With the abundance of medical data and the rapid development of machine learning (ML) technologies, new opportunities are provided for in-depth investigation of the mechanisms of CHF and the construction of predictive models. …”
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Association between Growth Hormone and Insulin-like Growth Factor-1 (IGF-1) Levels, Liver Function and Short-Term Survival of Paediatric Liver Recipients by R. M. Kurabekova, O. M. Tsiroulnikova, I. E. Pashkova, L. V. Makarova, N. P. Mozheiko, A. R. Monakhov, O. P. Shevchenko

“…The growth hormone/insulin-like growth factor-1 (IGF-1) system is an important humoral mediator of liver function with an inherent potential for assessing liver condition and survival prognosis following liver transplantation (LT).Aim. …”
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Value of Anterior Band of the Inferior Glenohumeral Ligament Area as a Morphological Parameter of Adhesive Capsulitis by Yun-Sic Bang, Junbeom Park, Sun Young Lee, Jiyeon Park, Sukhee Park, Young Joo, Young Uk Kim, Yoon Kyung Lee

“…We measured the aIGHLA and aIGHLT at the maximal view of the IGHL in the coronal plane using our picture archiving and communication system. The aIGHLA was measured at the whole cross-sectional area of the IGHL in the most hypertrophied segment of the coronal MR images. …”
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Accumulation and distribution of cadmium at organic-mineral micro-interfaces across soil aggregates by Qi Li, Linfeng Li, Bohao Yin, Xiaoyang Lin, Anwen Xiao, Weijie Xue, Hengjie Liu, Yichun Li

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Nutritional intake of micronutrient and macronutrient and type 2 diabetes: machine learning schemes by Mohammad Rashidmayvan, Amin Mansoori, Elahe Derakhshan-Nezhad, Davoud Tanbakuchi, Fatemeh Sangin, Maryam Mohammadi-Bajgiran, Malihehsadat Abedsaeidi, Sara Ghazizadeh, MohammadReza Mohammad Taghizadeh Sarabi, Ali Rezaee, Gordon Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

“…Abstract Background Diabetes mellitus, an endocrine system disease, is a common disease involving many patients worldwide. …”
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Optomechanical Gyroscope Based on Micro-Hemispherical Shell and Optical Ring Resonators by Jamal N. A. Hassan, Wenyi Huang, Maoyuan Wang, Senyu Zhang, Guangjun Wen, Yongjun Huang

“…Silicon photonic integrated circuits and micro-electro-mechanical systems enable the design of compact, high-performance micro-opto-electro-mechanical systems (MOEMS) gyroscopes, such as recently reported optomechanical gyroscopes. …”
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Body mass index impacts the lipid-lowing effects of statins in patients with type 2 diabetes by Lulu Sun, Zhuo Wang, Bai Wang, Yuxiang Jia, Qidi Zhao, Jingjun Zhao, Xingtao Huang

“…We aim to evaluate whether BMI will affect the lipid-lowing effects of statins in patients with T2DM.MethodsIn this retrospective analysis, we screened T2DM patients who were prescribed statins and underwent a 1-year outpatient follow-up recorded in the electronic medical record system. Patients were stratified into three groups: normal weight (BMI < 24 kg/m), overweight (24 kg/m2 ≤ BMI < 28 kg/m2), and obese (BMI ≥ 28 kg/m2). …”
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Regenerative fibroblasts derived from autologous skin tissue for the treatment of Sjögren’s syndrome: a case report by Zhao-Xia Ma, Xing-Fei Wu, Li Cao, Cheng-Yan Jiao, Dai-Ping Ma, Yun-Hui Zhao, Zhi-Xing Yang, Min Hu, Min Hu

“…BackgroundSjögren’s syndrome (SS) is a systemic autoimmune disease, with major symptoms including dry mouth and dry eyes, for which there is no effective treatment. …”
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A Path to High-Value Gastric Cancer Surgery Care Delivery by Swee H. Teh, MD, Sharon Shiraga, MD, Aaron M. Kellem, BS (Math), Robert A. Li, MD, David M. Le, MD, Said P. Arsalane, MSHA, Fawzi S. Khayat, MD, Yan Li, MD, I-Yeh Gong, MD, Jessica M. Lee, MD

“…To compare the outcomes of gastric cancer surgery using 2 different models of care within an integrated healthcare system from February 2012 to March 2023. The primary endpoint was the length of hospital stay. …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Previous research has established a significant connection between NTN1 and nervous system development. In recent years, mounting evidence indicates that NTN1 also plays a crucial role in tumorigenesis and tumor progression. …”
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Plant-Based Antigen Production Strategy for SARS-CoV-2 Nucleoprotein and RBD and Its Application for Detection of Antibody Responses in COVID-19 Patients by Katerina Takova, Valeria Tonova, Ivan Minkov, Eugenia S. Mardanova, Nikolai V. Ravin, Stanislav Kotsev, Maria Pishmisheva, Gergana Zahmanova

“…Our research validates the commercial potential of using plants as an expression system for recombinant protein production and their application as diagnostic reagents for serological detection of infectious diseases, hence lowering the cost of diagnostic kits.…”
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Immunologic and inflammatory consequences of SARS-CoV-2 infection and its implications in renal disease by Hiam Naiditch, Michael R. Betts, H. Benjamin Larman, Moshe Levi, Avi Z. Rosenberg

“…Early infection of both tissue and immune cells, such as macrophages, leading to pyroptosis-mediated inflammasome production in an organ system critical for systemic oxygenation likely plays a central role in the morbidity wrought by SARS-CoV-2. …”
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FORMATION OF STUDENTS’ SCIENTIFIC THINKING BASED ON THE LEARNING OF METHODS OF THE SUBSTANCE ANALYSIS by M. A. Kosareva, L. A. Baikova, E. A. Nikonenko, V. V. Vaitner, A. N. Gabdullin

“…Methodological framework of the article involves the concepts of chemical and natural-science education at the higher school; the principles of the system-based, cognitive, practice-focused and competence-based training. …”
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Methodological aspects in gastroenteric methane evaluation trial in water buffalo by Maria Chiara La Mantia, Emanuela Rossi, Francesco Cenci, David Meo Zilio, Roberto Steri, Miriam Iacurto, Antonella Chiariotti

“…The LMD is a remote CH4 monitoring system for air used in other ruminants, but studies on buffalo are scarce. …”
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Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal by Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani

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Assessing the Causal Relationship Between Various Immune Cells and Attention Deficit Hyperactivity Disorder: Mendelian Randomization Study by Qian Ge, Zhongyan Li, Weijing Meng, Chen Cai, Mengdi Qiu, Yafei Liu, Haibo Zhu

“…ABSTRACT Background Immune system modulation has been shown to have a significant impact on attention deficit hyperactivity disorder (ADHD). …”
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Protocol on establishing a prospective enhanced surveillance of vaccine preventable diseases in residential aged care facilities in Central Queensland, Australia: an observational... by Mohammad Rashidul Hashan, Robert Booy, Michael Kirk, Gulam Khandaker, Gwenda Chapman, Jacina Walker, Sonya Jayne Davidson, Jill Auriac, Nicolas Smoll, Delwar Akbar

“…The increasing burden of emerging and existing VPDs (eg, COVID-19, influenza, pneumococcal, pertussis and varicella-zoster) necessitates the establishment of an active enhanced surveillance system to provide real-time evidence to devise strategies to reduce the burden of VPDs in RACFs.Method and analysis This study proposes a prospective active enhanced surveillance that will be implemented in RACFs across the Central Queensland (CQ) region. …”
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5G Networks Security Mitigation Model: An ANN-ISM Hybrid Approach by Rafiq Ahmad Khan, Habib Ullah Khan, Hathal Salamah Alwageed, Hussein Al Hashimi, Ismail Keshta

“…This paper presents a new security mitigation model using artificial neural network (ANN) with interpretive structure modeling (ISM) to improve the 5G network security system. The main goal of this study is to develop a 5G network security mitigation model (5GN-SMM) that leverages the predictive capabilities of ANN and the analysis of ISM to identify and mitigate security threats by providing practices in 5G networks. …”
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