Seroprevalence of transfusion-transmissible infections among family replacement donors and voluntary non-remunerated blood donors during the COVID-19 pandemic in sub Saharan Africa by Macoura Gadji, Youssou Bamar Gueye, David Motto, Saliou Diop

“…Comparison of HIV, HCV and syphilis markers seroprevalence showed no statistically significant difference between new voluntary donors and new family replacement donors (p>0.05). …”
Get full text

A Mobile Based Technology to Improve Male Involvement in Antenatal Care. by Muhoza, B. Gloria, Ssemaluulu, Paul Mukasa, Mabirizi, Vicent

“…The first visit which is expected to screen and treat anaemia, and syphilis, screen for risk factors and medical conditions that can be best dealt with in early pregnancy and initiate prophylaxis if required (e.g., for anaemia and malaria) is recommended to be made before the end of the fourth month of pregnancy. …”
Get full text

A Mobile Based Technology to Improve Male Involvement in Antenatal Care. by Gloria, Muhoza B., Mukasa, Ssemaluulu Paul, Mabirizi, Vicent

“…The first visit which is expected to screen and treat anaemia, syphilis, screen for risk factors and medical conditions that can be best dealt with in early pregnancy and initiate prophylaxis if required (e.g., for anaemia and malaria) is recommended to be made before the end of the fourth month of pregnancy. …”
Get full text

Insights into Treponema pallidum genomics from modern and ancient genomes using a novel mapping strategy by Marta Pla-Díaz, Gülfirde Akgül, Martyna Molak, Louis du Plessis, Hanna Panagiotopoulou, Karolina Doan, Wiesław Bogdanowicz, Paweł Dąbrowski, Maciej Oziembłowski, Barbara Kwiatkowska, Jacek Szczurowski, Joanna Grzelak, Natasha Arora, Kerttu Majander, Fernando González-Candelas, Verena J. Schuenemann

“…To conduct this comparison, we created a genomic dataset comprising 77 modern and ancient genomes from the three subspecies of T. pallidum, including a newly sequenced seventeenth century genome (35X mean coverage) of a syphilis-causing strain (designated as W86). Our findings show that recombination detection was consistent across different references, but the choice of reference significantly affected ancient genome reconstruction and phylogenetic inferences. …”
Get full text

Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…In 2015, estimated primary aetiologies for vaginal discharge were candidiasis (69.4% [95% confidence interval (CI): 44.3% to 86.6%], n = 50), bacterial vaginosis (50.0% [95% CI: 32.3% to 67.8%], n = 39), chlamydia (16.2% [95% CI: 8.6% to 28.5%], n = 50), and trichomoniasis (12.9% [95% CI: 7.7% to 20.7%], n = 80); for urethral discharge were gonorrhoea (77.1% [95% CI: 68.1% to 84.1%], n = 68) and chlamydia (21.9% [95% CI: 15.4% to 30.3%], n = 48); and for genital ulcer were herpes simplex virus type 2 (HSV-2) (48.3% [95% CI: 32.9% to 64.1%], n = 47) and syphilis (9.3% [95% CI: 6.4% to 13.4%], n = 117). Temporal variation was substantial, particularly for genital ulcer where HSV-2 replaced chancroid as the primary cause. …”
Get full text

Trends and distribution patterns of infant mortality and maternal HIV positivity in South Africa: A decade review (2007 - 2016) by M Makhele, N Ledibane, H Ramatsoma, A Musekiwa

“…This study used a cross-sectional study design by analysing secondary data on infant mortality from the 2007 and 2016 Statistics South Africa Community Surveys (CSs), as well as data from the 2007 National Antenatal Sentinel HIV and Syphilis Prevalence Survey. (Antenatal HIV Sentinel Survey – ANCHSS). …”
Get full text

Progress on HIV and other sexually transmitted infections elimination among youth and adults across BRICS-plus countries: Results from the Global Burden of Disease Study 2021 by Rizhen Wang, Yinuo Sun, Huan Wang, Xiaoran Yu, JiYan Ma, Zuokun Liu, Jing Li, Zhiyong Zou, Yangmu Huang

“…There were evident period risks of morbidity for HIV in Russia and Iran since 2012 and for syphilis and gonorrhea in Brazil since 2012. Younger generations had a higher risk of contracting HIV in Brazil, China, Egypt, Iran, and Russia, and other STIs in Brazil, India, Iran, and South Africa, particularly genital herpes. …”
Get full text

Maternal Hepatitis B Infection Burden, Comorbidity and Pregnancy Outcome in a Low-Income Population on the Myanmar-Thailand Border: A Retrospective Cohort Study by Marieke Bierhoff, Chaisiri Angkurawaranon, Aung Myat Min, Mary Ellen Gilder, Nay Win Tun, Arunrot Keereevijitt, Aye Kyi Win, Elsi Win, Verena Ilona Carrara, Tobias Brummaier, Cindy S. Chu, Laurence Thielemans, Kanlaya Sriprawat, Borimas Hanboonkunupakarn, Marcus Rijken, François Nosten, Michele van Vugt, Rose McGready

“…Women with a confirmed HBsAg status, HIV- and syphilis-negative at first antenatal care screening, singleton fetus and known pregnancy outcome (Aug-2012 to Dec-2016) were included. …”
Get full text

Should the Food and Drug Administration Limit Placebo-Controlled Trials? by Max Goodman, Connor Pedersen

“…Throughout the 20th century there have been numerous bioethical tragedies, including but not limited to the Holocaust and the Tuskegee Syphilis Study.[3] These and other transgressions have become an impetus for establishing ethical research standards preventing human exploitation in the name of science. …”
Get full text

The Bioethics-CSR Divide by Caio Caesar Dib

“…The publication of the Belmont Report[12] in the aftermath of the Tuskegee Syphilis Experiment, as well as the creation of committees such as the “God Committee,”[13] which aimed to develop and enforce criteria for allocating scarce dialysis machines, exemplify this shift. …”
Get full text