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Role of MicroRNA in Governing Synaptic Plasticity
Published 2016-01-01“…Although synaptic plasticity in neural circuits is orchestrated by an ocean of genes, molecules, and proteins, the underlying mechanisms remain poorly understood. …”
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Synaptic Plasticity Changes: Hallmark for Neurological and Psychiatric Disorders
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Hepatocyte Growth Factor in Synaptic Plasticity and Alzheimer's Disease
Published 2010-01-01“…This review describes the role of HGF in hippocampal neurons, synaptic plasticity, and the memory impairment condition, Alzheimer's disease.…”
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Microglia and Spinal Cord Synaptic Plasticity in Persistent Pain
Published 2013-01-01“…In this review, we discuss the recent findings illustrating the importance of microglial mediators in regulating synaptic plasticity of the excitatory and inhibitory pain circuits in the spinal cord, leading to enhanced pain states. …”
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Synaptic Plasticity and Neurological Disorders in Neurotropic Viral Infections
Published 2015-01-01“…Although these neurotropic viruses are able to be harbored in or infect the nervous system, not all the neurotropic viruses have been reported to cause disrupted synaptic plasticity and impaired cognitive functions. In this review, we have discussed the neurotropic viruses, which play a major role in altered synaptic plasticity and neurological disorders.…”
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In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders
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P-Body Components, microRNA Regulation, and Synaptic Plasticity
Published 2007-01-01“…Namely, that P-body proteins may play important roles in regulation of dendrite-localized mRNAs and, thereby, in synaptic plasticity. A wide range of protein localization and early functional data support this hypothesis. …”
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Synaptic plasticity in fronto-insular circuits underlying stress susceptibility and resilience
Published 2025-02-01Get full text
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Transcriptional Control of Synaptic Plasticity by Transcription Factor NF-κB
Published 2016-01-01“…Activation of nuclear factor kappa B (NF-κB) transcription factors is required for the induction of synaptic plasticity and memory formation. All components of this signaling pathway are localized at synapses, and transcriptionally active NF-κB dimers move to the nucleus to translate synaptic signals into altered gene expression. …”
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Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome
Published 2016-01-01“…But for now, most studies excessively emphasized the one-sided factor on the change of synaptic plasticity participating in the generation of anxiety during the development of FXS. …”
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BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex
Published 2014-01-01“…Our results indicate that BACE1 plays an essential role in sensory experience-dependent homeostatic synaptic plasticity in the neocortex.…”
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Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease
Published 2016-01-01“…Here, we studied synaptic plasticity phenomena and evaluated ERKs activation in the hippocampus of BALB/c NPC1−/− mice, a well described animal model of the disease. …”
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The Role of Neuroglial Crosstalk and Synaptic Plasticity-Mediated Central Sensitization in Acupuncture Analgesia
Published 2021-01-01“…This study summarizes the pathogenesis of central sensitization from the perspective of neuroglial crosstalk and synaptic plasticity and underlines the related analgesic mechanisms of acupuncture. …”
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Modulating synaptic plasticity with metal−organic framework for information-filterable artificial retina
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Tau oligomers impair memory and synaptic plasticity through the cellular prion protein
Published 2025-01-01“…To investigate whether PrPC mediates TauO detrimental activities, we compared their effects on memory and synaptic plasticity in wild type (WT) and PrPC knockout (Prnp 0/0) mice. …”
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Inhibition of DNA Methylation Impairs Synaptic Plasticity during an Early Time Window in Rats
Published 2016-01-01“…Although the importance of DNA methylation-dependent gene expression to neuronal plasticity is well established, the dynamics of methylation and demethylation during the induction and expression of synaptic plasticity have not been explored. Here, we combined electrophysiological, pharmacological, molecular, and immunohistochemical approaches to examine the contribution of DNA methylation and the phosphorylation of Methyl-CpG-binding protein 2 (MeCP2) to synaptic plasticity. …”
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NMDA Receptor Subunits Change after Synaptic Plasticity Induction and Learning and Memory Acquisition
Published 2018-01-01“…Changes in GluN1 or NMDAR levels induced by synaptic plasticity and by spatial memory formation seem to occur in different waves of NMDAR transport/expression/degradation, with a net increase at the postsynaptic side and a rise in expression at both the spine and neuronal soma. …”
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Effects of Treadmill Exercise on Hippocampal Synaptic Plasticity and Expression of Related Proteins in Aging Mice
Published 2023-06-01Subjects: Get full text
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Proteomic Analysis Reveals the Vital Role of Synaptic Plasticity in the Pathogenesis of Temporal Lobe Epilepsy
Published 2022-01-01“…Consequently, the synaptic plasticity-related proteins and synaptic structure were investigated to verify it. …”
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