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Muscarinic cannabinoid suppression of excitation, a novel form of coincidence detection
Published 2025-02-01Subjects: Get full text
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Mitochondrial ROS modulate presynaptic plasticity in the drosophila neuromuscular junction
Published 2025-02-01Subjects: “…Activity-dependent short-term synaptic plasticity…”
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Neural activity responsiveness by maturation of inhibition underlying critical period plasticity
Published 2025-01-01Subjects: Get full text
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Analyzing the potential of neuronal pentraxin 2 as a biomarker in neurological disorders: A literature review
Published 2024-12-01Subjects: Get full text
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MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway
Published 2025-02-01Subjects: Get full text
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DNA methylation, histone acetylation in the regulation of memory and its modulation during aging
Published 2025-01-01“…Dysregulation of synaptic plasticity gene expression affects memory during aging and neurodegenerative diseases. …”
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Ripples Make Waves: Binding Structured Activity and Plasticity in Hippocampal Networks
Published 2011-01-01“…Such events facilitate memory formation by optimising the conditions for synaptic plasticity to occur between contingent neural elements. …”
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Cellular Signal Mechanisms of Reward-Related Plasticity in the Hippocampus
Published 2012-01-01“…Consequently, there is an intense interest in the mechanisms that underline learning and memory. Synaptic plasticity has been hypothesized to be the neuronal substrate for learning. …”
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Lack of UBE3A-Mediated Regulation of Synaptic SK2 Channels Contributes to Learning and Memory Impairment in the Female Mouse Model of Angelman Syndrome
Published 2022-01-01“…In the present study, we investigated UBE3a-mediated regulation of synaptic plasticity and fear-conditioning in female AS mice. …”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration
Published 2019-01-01“…Here, we provide an overview of how GSK-3β is regulated in physiological synaptic plasticity and how aberrant GSK-3β activity contributes to the development of dysfunctional synaptic plasticity in neuropsychiatric and neurodegenerative disorders.…”
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Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses
Published 2002-01-01“…Here we discuss the evidence that these basic mechanisms are used during developmental synaptic plasticity.…”
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Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…Synaptic plasticity refers to the ability of neurons to strengthen or weaken synaptic efficacy in response to activity and is the basis for learning and memory. …”
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Hippocampal Regulation of Postsynaptic Density Homer1 by Associative Learning
Published 2017-01-01“…Genes involved in synaptic plasticity, particularly genes encoding postsynaptic density proteins, have been recurrently linked to psychiatric disorders including schizophrenia and autism. …”
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Erasing Synapses in Sleep: Is It Time to Be SHY?
Published 2012-01-01“…SHY is intuitively appealing because it relates the homeostatic regulation of sleep to an important function (synaptic plasticity). SHY has also received important experimental support from recent studies in Drosophila melanogaster. …”
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The Many Forms and Functions of Long Term Plasticity at GABAergic Synapses
Published 2011-01-01“…Thus, the understanding of inhibitory synaptic plasticity is crucial to fully comprehend the physiology of brain circuits. …”
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Functional Metaplasticity of Hippocampal Schaffer Collateral-CA1 Synapses Is Reversed in Chronically Epileptic Rats
Published 2017-01-01“…A major open question applies to the interdependence between synaptic plasticity and its behavioral correlates. In this context, it has become clear that behavioral aspects may impact subsequent synaptic plasticity, a phenomenon termed behavioral metaplasticity. …”
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Protocol for generating human assembloids to investigate thalamocortical and corticothalamic synaptic transmission and plasticity
Published 2025-03-01“…Summary: Human induced pluripotent stem cells (hiPSCs) can be used to generate assembloids that recreate thalamocortical circuitry displaying short-term and long-term synaptic plasticity. Here, we describe a protocol for differentiating hiPSCs into thalamic and cortical organoids and then fusing them to generate thalamocortical assembloids. …”
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Synaptic motility and functional stability in the whisker cortex
Published 2025-01-01“…Here we used the whisker system of rats and mice to study the interplay between synaptic plasticity (motility) and the transmission of sensory signals downstream. …”
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Spindle Activity Orchestrates Plasticity during Development and Sleep
Published 2016-01-01“…Along with these functional differences, separate synaptic plasticity mechanisms seem to be recruited. Here, we review the generation of spindle oscillations in the developing and adult brain and discuss possible implications of their differences for synaptic plasticity. …”
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