Chemical composition and insecticidal potential of botanical fractionation extracts for the management of Sitophilus zeamais Motschulsky, 1855 (Coleoptera: Curculionidae) in stored... by Fikadu Kifle, Melaku Girma, Araya Gebresilassie, Yitbarek Woldehawariat, Estifanos Ele

“…The findings can contribute to developing eco-friendly, safer and more sustainable alternatives to synthetic chemical insecticides.…”
Get full text

Direct effects of prolonged TNF-α and IL-6 exposure on neural activity in human iPSC-derived neuron-astrocyte co-cultures by Noah Goshi, Doris Lam, Chandrakumar Bogguri, Vivek Kurien George, Aimy Sebastian, Jose Cadena, Nicole F. Leon, Nicholas R. Hum, Dina R. Weilhammer, Nicholas O. Fischer, Heather A. Enright

“…A common factor among these conditions is a sustained immune response and increased levels of inflammatory cytokines. …”
Get full text

Epithelial NSD2 maintains FMO‐mediated taurine biosynthesis to prevent intestinal barrier disruption by Yue Xu, Xiuying Xiao, Chunxiao Ma, Ziyi Wang, Wenxin Feng, Hanyu Rao, Wei Zhang, Ningyuan Liu, Rebiguli Aji, Xiangjun Meng, Wei‐Qiang Gao, Li Li

“…Key points In this study, we investigated the role of the histone methyltransferase NSD2 in preventing intestinal barrier disruption by sustaining taurine biosynthesis. NSD2 levels were reduced in both human specimens and mouse models of IBD. …”
Get full text

MaxEnt-Based Predictions of Suitable Potential Distribution of <i>Leymus secalinus</i> Under Current and Future Climate Change by Shimeng Zhao, Zongxian Zhang, Changyu Gao, Yiding Dong, Zeyao Jing, Lixia Du, Xiangyang Hou

“…The results of this study revealed the suitable climatic conditions and potential distribution range of <i>L. secalinus</i>, which can provide a reference for the conservation, introduction, and cultivation of <i>L. secalinus</i> in new ecological zones, avoiding the blind introduction of inappropriate habitats, and is also crucial for sustaining the economic benefits associated with <i>L. secalinus</i> ecological services.…”
Get full text

Population Dynamics of the Crocodile Shark, <i>Pseudocarcharias kamoharai</i>, in the Tropical Equatorial Pacific Ocean, Ecuador by Marcos Douglas Calle-Morán, Eugenio Alberto Aragón-Noriega, Ana Rosa Hernández-Téllez, Emigdio Marín-Enríquez, Javier Tovar-Ávila, Juan Francisco Arzola-González, Jorge Payán-Alejo

“…The obtained BRPs were <i>F_opt</i> = 0.10 and 0.12 and <i>F_lim</i> = 0.16, which showed that the optimal fishing levels (best possible capture) to achieve long-term sustainable exploitation of the stock encompass 10 to 16% of the fishing effort applied for this species. …”
Get full text

The role of health literacy in intervention studies targeting children living with overweight or obesity and their parents—a systematic mixed methods review by Heidi Holmen, Heidi Holmen, Tone Nygaard Flølo, Tone Nygaard Flølo, Christine Tørris, Astrid Torbjørnsen, Kari Almendingen, Kirsti Riiser, Kirsti Riiser

“…Future research should focus on integrating health literacy into weight management interventions in a systematic and theory-driven manner, ensuring that these interventions are tailored to the specific needs of children and their families and can sustain behavior change over time.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?…”
Get full text

Upadacitinib in active non-radiographic axial spondyloarthritis: 2-year data from the phase 3 SELECT-AXIS 2 study by Filip Van den Bosch, Atul Deodhar, Denis Poddubnyy, Walter P. Maksymowych, Désirée van der Heijde, Tae-Hwan Kim, Mitsumasa Kishimoto, Xenofon Baraliakos, Xianwei Bu, Ivan Lagunes-Galindo, In-Ho Song, Peter Wung, Koji Kato, Anna Shmagel

“…In patients who received continuous upadacitinib, sustained improvement was observed through 2 years of treatment across efficacy endpoints including disease activity, pain, function, enthesitis, quality of life, and MRI measures of inflammation. …”
Get full text

PLGA-based biocompatible nanoparticles improved anti-breast tumor efficacy of 1,25(OH)2D3 through the SOCS3/STAT3/EMT signaling axis by JinJing Pan, Ping Wang, Linghong Xiong, Wenqing Yang, Jie Li, Kai Yang, Bingyan Li

“…However, due to the susceptibility of 1,25(OH)2D3 to degradation in the tumor microenvironment, higher doses were required to sustain its efficacy. This elevated dosage could lead to significant side effects, thereby constraining its practical application in clinical settings. …”
Get full text

Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…The level of HCV RNA was undetectable both at the 4-th week, and at the 12-th week (extended rapid virologic response) in 42 (75%) of 56 previously untreated patients, in 34 (89%) of 38 with relapses after previous treatment, in 4 (57%) of 7 with previous incomplete response, in 22 (52%) of 42 with the previous zero response and in 7 (70%) of 10 with previous virologic breakthrough. Sustained virologic response was achieved in 73 (80%) of patients available for analysis (n=91). …”
Get full text

CD4 T cell depletion increases memory differentiation of endogenous and CAR T cells and enhances the efficacy of Super2 and IL-33-armored CAR T cells against solid tumors by Chrystal Paulos, Mary Jo Turk, Megen C Wittling, Yina H Huang, Asmaa O Mohamed, David Tyler Boone, Shannon L Ferry, Melanie C Peck, Alicia M Santos, Haille E Soderholm

“…Multiple strategies improve persistence by increasing stem-like properties or sustaining CAR T cell activity with combination therapies. …”
Get full text

Leave no child behind: Using data from 1.7 million children from 67 developing countries to measure inequality within and between groups of births and to identify left behind popul... by Antonio P Ramos, Martin J Flores, Robert E Weiss

“…<h4>Background</h4>Goal 3.2 from the Sustainable Development Goals (SDG) calls for reductions in national averages of Under-5 Mortality. …”
Get full text

Modelling of the closed equilibrium system H2O–(CO2)W–CaCO3–NaH2PO4 for wastewater treatment applications by Ivar Zekker, Oleg Artemchuk, Ergo Rikmann, Kalev Uiga, Laura Daija, Faysal-Al Mamun, Andrejs E. Krauklis, Ruta Ozola-Davidane, Taavo Tenno, Toomas Tenno†

Get full text

Rainwater and fog harvesting from solar panels by I. Alazzam, K. Shatanawi, R. Al-Weshah

“…The scarcity of water resources in Jordan is driving the development and advances of non-conventional water techniques that enable integrated management of water resources in addressing water scarcity challenges and promoting sustainable water use. Water harvesting of rainwater and fog techniques is one of the viable solutions to mitigate the water scarcity effects in Jordan. …”
Get full text

Effects of different water and fertilizer treatments on the matrix properties and plant growth of tailings waste by Yanchen Li, Yang Yang, Jialin He, Shan Guo, Xuejing An, Yan Li, Rui Guo, Yipeng Lin, Ruipeng Zhang

“…Abstract Vegetation ecological restoration technology is widely regarded as an environmentally sustainable and green technology for the remediation of mineral waste. …”
Get full text

Long-Term Outcomes of a Health Information System-Based Feedback Intervention Study of Antimicrobial Prescriptions in Primary Care Institutions: Follow-Up of a Randomized Cross-Ove... by Yan Y, Yang J, Lu Y, Cui Z, Chang Y

“…It is reasonable to think that the desired effects will be difficult to maintain without sustained implementation of feedback intervention.Keywords: long-term outcomes, feedback intervention, antimicrobial prescriptions, health information system, primary care institutions…”
Get full text

Parejas heterosexuales serodiscordantes en Chiapas, México. La influencia del género en la expresión de la agencia/Heterosexual HIV-Discordant Couples in Chiapas, Mexico. The Influ... by Francisco Chong-Villareal, Teresa Margarita Torres-López

“…The men resorted to falling in love, to sustain a relationship, where the corresponding partner knew their diagnosis, from information that the men themselves gave them. …”
Get full text

Le port antique de Chelles (Seine-et-Marne) : une course après la rivière by Yann Le Jeune, Corinne Charamond, Christian Charamond

“…The latter are related to erosion due to the development of agriculture across the Marne watershed, which also led to the establishment of an increasingly marked flood regime. The riverbanks sustained various activities and endeavors aimed at maintaining access to water –digging, dredging, depositing backfill, and more advanced developments toward the north in hopes of following the river– an effort which could not be maintained for more than a century and which reflects a veritable race after the river. …”
Get full text

Spatial-Temporal Variation and Driving Forces of Carbon Storage at the County Scale in China Based on a Gray Multi-Objective Optimization-Patch-Level Land Use Simulation-Integrated... by Gui Chen, Qingxia Peng, Qiaohong Fan, Wenxiong Lin, Kai Su

“…Exploring and predicting the spatiotemporal evolution characteristics and driving forces of carbon storage in typical mountain forest ecosystems under land-use changes is crucial for curbing the effects of climate change and fostering sustainable, eco-friendly growth. The existing literature provides important references for our related studies but further expansion and improvements are needed in some aspects. …”
Get full text

Climate change risks illustrated by the Intergovernmental Panel on Climate Change (IPCC) “burning embers” by P. Marbaix, P. Marbaix, P. Marbaix, A. K. Magnan, A. K. Magnan, A. K. Magnan, V. Muccione, V. Muccione, P. W. Thorne, Z. Zommers

Get full text

A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats by Pleydell, David R.J., Ndong Bass, Innocent, Mba Djondzo, Flaubert Auguste, Meta Djomsi, Dowbiss, Kouanfack, Charles, Peeters, Martine, Cappelle, Julien

Get full text