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14961
Localized propranolol delivery from a copper-loaded hydrogel for enhancing infected burn wound healing via adrenergic β-receptor blockade
Published 2025-02-01“…Severe burn injuries immediately trigger a sustained systemic and local stress response. During this process, the sympathetic nervous system releases large amounts of catecholamines, which bind to β-adrenergic receptors (β-AR) on cell membranes, negatively affecting skin regeneration. …”
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14962
Conducting clinical trials with self-collection of pharmacokinetic samples: Experience from an exploratory, phase 1, open-label trial of centanafadine SR in healthy individuals
Published 2025-02-01“…Participants received a single 100-mg oral dose of centanafadine sustained release at visits 1, 2, and 4. Pharmacokinetic samples, electrocardiograms (ECGs; 6-lead [participant] and 12-lead [staff]), and vital signs were collected by clinical personnel (visit 1), under staff supervision (visit 2), and remotely (visit 4), facilitated by the Verily clinical trial application. …”
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14963
Evaluation of urban water cycle health status based on DPSIRM framework and AHP-FCE-Cloud model
Published 2025-01-01“…Furthermore, the analysis of obstacles provides theoretical support for promoting sustainable urban development.…”
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14964
A narrative literature review to inform the development of a health threats preparedness framework in Ireland
Published 2025-02-01“…Adequate resources are required to operationalize effective and sustainable preparedness. Public health leadership must be to the fore.ConclusionAn effective health threats preparedness approach is legislatively mandated for European Member States. …”
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14965
Preparation of Composite Films Based on Methyl Cellulose/Polyvinyl Alcohol-loaded Nanosilver (AgNPs@PVA/MC) and Its Effect on Storage Quality of Ougan
Published 2025-01-01“…Infrared spectroscopy and thermogravimetric analysis showed that composite film with 0.1% AgNPs content had good bonding and thermal stability. 0.1%AgNPs@PVA/MC composite film could effectively reduce the weight loss rate of Ougan during storage, and reduce the consumption rate of soluble solid, titratable acid and VC, delay the maturation of Ougan and significantly inhibit the growth of Penicillium citrinum, which could better maintain the quality of Ougan during the storage period, this study provided support for the sustainable development of Ougan industry.…”
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14966
Entrepreneurship in Medical Education: Evaluation of the Entrepreneurship in Healthcare Seminar Series
Published 2024-12-01“…Physicians are ideally positioned to create sustainable healthcare innovations. However, few medical programs in Canada provide training for students to pursue innovation and entrepreneurship. …”
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14967
Molecular mobility and dielectric properties of dendronized side chain liquid crystalline polyamines with benzoate groups as lateral spacers
Published 2025-01-01“…Dendronized polymers are suitable candidates for the preparation of biomimetic membranes for ion transport in fuel cells, which is nowadays a sustainable way of producing electrical energy. To prepare materials for these high-technology applications, it is necessary to understand the role of the different parts that make up these supramolecular structures. …”
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14968
Efficacy and fibrinogen correlations of defibrinogen therapy in idiopathic sudden sensorineural hearing loss
Published 2025-02-01“…The study findings suggest that batroxobin therapy not only improves hearing recovery but also maintains plasma fibrinogen at a low and safe level. In addition, sustained low fibrinogen level throughout treatment serves as a predictor for better prognosis in TD-ISSNHL.…”
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14969
Reducing catheter-associated urinary tract infections in a large health system: a quality improvement approach using a fractal management system
Published 2024-01-01“…Our goal was to improve the CAUTI rates through multiple hospitals through implementing sustainable practices, including enhancing communication, provider engagement, accountability, and transparency in reporting to achieve long-term improvements. …”
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14970
Hybrid parking space prediction model: integrating ARIMA, Long short-term memory (LSTM), and backpropagation neural network (BPNN) for smart city development
Published 2025-01-01“…The proposed hybrid model can potentially improve parking space prediction, contributing to sustainable and economical smart cities and enhancing the quality of life for citizens.…”
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14971
Management of Neglected Floating Knee with Rotational Deformity and Limb Shortening Using the Ortho-SUV Frame: A Case Report
Published 2025-01-01“…Hereby the authors present the case of a 38-year-old male who sustained a floating knee injury following a high-velocity Road Traffic Accident (RTA). …”
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14972
Inversion of Water Quality Parameters from UAV Hyperspectral Data Based on Intelligent Algorithm Optimized Backpropagation Neural Networks of a Small Rural River
Published 2025-01-01“…The continuous and effective monitoring of the water quality of small rural rivers is crucial for rural sustainable development. In this work, machine learning models were established to predict the water quality of a typical small rural river based on a small quantity of measured water quality data and UAV hyperspectral images. …”
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14973
<i>AcOTApks</i> Gene-Based Molecular Tools to Improve Quantitative Detection of the Mycotoxigenic Fungus <i>Aspergillus carbonarius</i>
Published 2024-12-01“…The results showed that both analytical methods can be suitable for improving the sustainable management of OTA contamination in grapes and their derivatives.…”
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14974
A Metapopulation Model to Assess Water Management Impacts on the Threatened Australian Lungfish, <i>Neoceratodus forsteri</i>
Published 2025-01-01“…As this long-lived species (at least 77 years) has delayed maturity (mature at 10 years), field monitoring alone will not be enough to inform the challenge of ensuring sustainable populations. A stochastic metapopulation model was developed for the Burnett River (Southeast Queensland, Australia), an important habitat for the lungfish that is a highly regulated system with extensive water infrastructure. …”
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14975
The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver
Published 2025-03-01“…We showed successful but low efficient triple trafficking by LNP-rAAV2 carrying EGFP, human factor IX (hFIX), and luciferase (luc), due to its encapsulation characteristic. Additionally, sustained TAC treatment, which dose-dependently downregulated the anti-rAAV2 antibodies, permitted rAAV2 re-administration at dosages of ≥45 mg/kg/3 days. …”
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14976
Sex differences in exercise‐induced arterial hypoxemia and pulmonary edema following high‐intensity exercise in highly trained endurance athletes
Published 2025-01-01“…F: 40.4 (7.5) min, p = 0.006), while females sustained a higher percentage of their visit 1 heart rate (M: 94 (1) vs. …”
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14977
Understanding sociodemographic differences in climate behavior, climate policy acceptance, and political participation
Published 2025-01-01“…Higher education was linked to less sustainable behavior, greater policy acceptance, and higher participation, while municipality size was only linked to the latter two. …”
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14978
The role and contribution of civil society and community actors in COVID-19 prevention and control: the case of the COMVID COVID-19 movement in Burkina Faso
Published 2023-04-01“…Communities should play a crucial role in the fight against public health emergencies but ensuring their effective and sustained engagement remains a challenge in many countries. …”
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14979
Strategies for Healthcare Disaster Management in the Context of Technology Innovation: the Case of Bulgaria
Published 2024-06-01“…In Bulgaria, integrating technology and innovation is crucial for advancing sustainable healthcare disaster management, enhancing disaster response and recovery, and minimizing long-term environmental and social impacts. …”
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14980
Do land models miss key soil hydrological processes controlling soil moisture memory?
Published 2025-01-01“…Most land surface models (LSMs) tend to overestimate surface soil moisture and its persistency (or SMM), sustaining spuriously large soil surface evaporation during dry-down periods. …”
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