Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival by Monika Komza, Jesminara Khatun, Jesse D. Gelles, Andrew P. Trotta, Ioana Abraham-Enachescu, Juan Henao, Ahmed Elsaadi, Andriana G. Kotini, Cara Clementelli, JoAnn Arandela, Sebastian El Ghaity-Beckley, Agneesh Barua, Yiyang Chen, Mirela Berisa, Bridget K. Marcellino, Eirini P. Papapetrou, Masha V. Poyurovsky, Jerry Edward Chipuk

“…Furthermore, we examined the therapeutic potential of these observations by treating a cohort of primary AML patient samples with KL-11743 and witnessed similar dependency on mitochondrial respiration for sustained cellular survival. Together, these data highlight conserved adaptations to acute glucose uptake inhibition in diverse leukemic models and AML patient samples, and position mitochondrial respiration as a key determinant of treatment success.…”
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Characterization and classification of soils in the irrigable land of Achewa small-scale irrigation area, Itang special district, southwest Gambella, Ethiopia by Wasihun Mengiste, Dereje Tsegaye, Samuel Dagalo, Teshome Yitbareke

“…Therefore, implementing site-specific soil management techniques is recommended to enhance and sustain soil fertility and optimize crop and vegetable production, for ensuring long-term soil productivity in the study area.…”
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Protocol to assess bottlenecks inhibiting the scaling up of evidence-based family planning practices in low-income and middle-income countries using mixed methods by James Kiarie, Moazzam Ali, Rita Kabra, Komal Preet Allagh, Kathryn Church, Abdulmumin Saad, Petrus Steyn

“…To gain a better understanding of the factors that may be hindering the sustained scale-up of these interventions, WHO has developed an assessment protocol to systematically identify the health systems’ ‘bottlenecks’ to implementation and to then identify solutions and develop strategies to address them.Methods and analysis A mixed method approach that includes document review, secondary data analysis (from surveys, service delivery data and case studies) and key informant interviews with policymakers, programme managers, health providers and community groups will be used to identify bottlenecks. …”
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Time Series Classification of Raw Voice Waveforms for Parkinson's Disease Detection Using Generative Adversarial Network-Driven Data Augmentation by Marta Rey-Paredes, Carlos J. Perez, Alfonso Mateos-Caballero

“…The experiments were performed using the speech task of sustained vowel /a/ in the PC-GITA database, which contains the recordings of healthy and PD subjects. …”
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Short-term follow-up of antibiotic-loaded calcium sulfate in treating chronic periprosthetic joint infection during two-stage revision by Xiao Sun, Jun Tan, Lijuan Zhan, Mingkui Sheng, Zhongxin Tang, Lingxiao Wu, Jianzhong Xu, Haijun Ma

“…Additionally, there was no significant difference in postoperative complication rates between the two groups.ConclusionThe use of antibiotic-loaded calcium sulfate in two-stage revision surgery for chronic knee PJI ensures sustained local antibiotic release at high concentrations, leading to rapid reduction in inflammatory markers, effective infection control, and a low complication rate. …”
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Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet (HFD) by Tomasz Sawczyn, Dominika Stygar, Katarzyna Nabrdalik, Michał Kukla, Oliwia Masri, Łukasz Magrowski, Wojciech Karcz, Jerzy Jochem

“…Metabolic surgery procedures are designed not only for sustained weight loss but also for achieving positive metabolic changes, including improved glucose tolerance and insulin sensitivity, along with an increase in energy expenditure. …”
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The role of artificial intelligence in pandemic responses: from epidemiological modeling to vaccine development by Mayur Suresh Gawande, Nikita Zade, Praveen Kumar, Swapnil Gundewar, Induni Nayodhara Weerarathna, Prateek Verma

“…The review also focuses on screening, forecasting, contact tracing and monitoring the virus-causing pandemic. It advocates for sustained research, real-world implications, ethical application and strategic integration of AI technologies to strengthen our collective ability to face and alleviate the effects of global health issues.…”
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Atomized Neutrophil Membrane-coated MOF Nanoparticles for Direct Delivery of Dexamethasone for Severe Pneumonia by Yixiao Yang, Lizhen Yan, Han Zhang, Chuanguang Xiao, Kai Wang

“…Results: Drug release experiments revealed UiO66-Dex@NMP to exhibit favorable sustained-release properties. Additionally, UiO66-Dex@NMP demonstrated excellent targeting capabilities both in vitro and in vivo. …”
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Characterization of Avocado (<i>Persea americana</i> Mill) Seed Extract from the Variety Semil 34 Cultivated in the Dominican Republic by Ramon Sanchez-Rosario, Luis Castillo, Alejandra Féliz-Jiménez, Sebastián Vargas, Ramón Pérez-Romero, Mónica Aquino, Maha T. Abutokaikah

“…This study demonstrates the potential of the avocado seed as a source of bioactive compounds and hence a functional ingredient, supporting its value in sustainable production and its possible contribution to environmental goals by reducing waste in the avocado industry.…”
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Bond behavior of galvanized iron fiber reinforced concrete with recycled coarse aggregate and model prediction using machine learning by Md. Jahidul Islam, Ummul Wara Labiba, Tasfiah Faisal Chowdhury, Md. Shahjalal, Tanvir Mustafy, Tanvir Hassan Tusher

“…By utilizing locally available and cost-effective GIF alongside RCA, these findings contribute to sustainable construction practices by enhancing the mechanical and bond properties of concrete while addressing environmental concerns.…”
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Modeling the influence of external heat flux on thermal characteristics of the silica aerogel/paraffin in a cylindrical atomic duct by Lishan Geng, Ali B.M. Ali, Shahram Babadoust, Anjan Kumar, Barno Abdullaeva, Rasha Abed Hussein, Soheil Salahshour, Sh Esmaeili

“…As the price of fuel rises and the environmental impact of greenhouse gases intensifies, a larger population is opting for alternative sources of sustainable energy. Currently, scientists are facing challenges in discovering an energy-saving method that is effective in diverse scenarios and is user-friendly. …”
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Complex Power System Status Monitoring and Evaluation Using Big Data Platform and Machine Learning Algorithms: A Review and a Case Study by Yuanjun Guo, Zhile Yang, Shengzhong Feng, Jinxing Hu

“…Efficient and valuable strategies provided by large amount of available data are urgently needed for a sustainable electricity system that includes smart grid technologies and very complex power system situations. …”
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DNA methylation of ACADS promotes immunogenic cell death in hepatocellular carcinoma by Ze Qian, Yifan Jiang, Yacong Wang, Yu Li, Lin Zhang, Xiaofeng Xu, Diyu Chen

“…Methylation of ACADS MS-2 was associated with worse survival, and mutation of MS-2 increased ACADS mRNA levels in five HCC cell lines. Sustained overexpression of ACADS not only suppressed the proliferation, migration, and invasion of HCC cells but also promoted immunogenic cell death (ICD) via the upregulation of calreticulin. …”
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Multipath joint ablation strategy for focal atrial tachycardia originating from patent foramen ovale: a case report by Fuqiang Liu, Yifei Li, Song Yan, Lijun Liu, Kaiyu Zhou, Yimin Hua

“…Recent research has identified cases of sustained FAT originating from the interatrial septum (IAS); a subset of cases presents a unique challenge, with foci originating from the peri-patent foramen ovale (peri-PFO), requiring specialized management during catheter ablation. …”
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Radial head arthroplasty vs. open reduction and internal fixation in Mason 3 radial head fractures: meta-analysis of prospective trials by Domenico De Mauro, MD, Sami Abou Chakra, Francesco Liuzza, MD, Amarildo Smakaj, MD, Giuseppe Rovere, MD, PhD, Giulio Maccauro, MD, Omar El Ezzo, MD

“…Background: Radial head fractures (RHF) represent about one-third of all elbow fractures, comprising approximately 2%-5% of all fractures sustained. The aims of this systematic review and meta-analysis are as follows: (i) to compare complications rate in patients undergoing radial head arthroplasty (RHA) or open reduction and internal fixation as surgical treatments for Mason type 3 RHF; (ii) to compare clinical outcome and functional score in patients undergoing RHA or ORIF in Mason type 3 RHF. …”
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The Influence of the Cu-Al₂O₃ Ratio of the Receiving Tube in a 50 MW Hybrid Solar Plant by Guillermo Benítez-Olivares, Alejandro Torres-Aldaco, Raúl Lugo-Leyte, José Javier Valencia-López, Luis Alberto Romero-Vázquez, Helen D. Lugo-Méndez

“…These findings demonstrate the potential for hybrid solar thermal plants to provide sustainable and efficient solutions for industrial energy needs.…”
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Performance Evaluation of Bone Glue-Modified Asphalt by Asif Ali, Naveed Ahmad, Muhammad Adeel, Syed Bilal Ahmed Zaidi, Muhammad Sohail Jameel, Farsan Ali Qureshi, Waqas Haroon, Syeda Aamara Asif

“…The bone glue is produced from a sustainable source. It is a cost-effective and eco-friendly material. …”
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Nonlinear response and driving mechanisms of ecological restoration project effectiveness to drought by Xin Liu, Qi Wang, Xiaoyu Zhu, Yujun Zhang

“…The research offers a theoretical foundation for ecological restoration and sustainable development of the APTZNC and scientific guidance for implementing ecological restoration practices in other regions experiencing drought stress globally.…”
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Comparison of Different Materials Used in The Preparation Of Household Bioplastics and Evaluation of a Mixture of Animal Gelatin and Cornstarch by Kamar Shayah, Joseph Shenekji, Durra Balt, Siran Arabanian, Joudy Awyga, Sawsan Salloum

“…The synergistic effects observed in the corn starch-gelatin bioplastic suggest that this formulation represents a promising sustainable alternative to traditional petroleum-based plastics. …”
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Bioelectronic osteosynthesis plate to monitor the fracture bone healing using electric capacitive variations by Diogo G. Pires, Nuno M. Silva, A. Completo, Marco P. Soares dos Santos

“…Over the past few decades, a sustained increase in the number of incidents and prevalent cases have been reported, as well as in the years lived with disability. …”
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