Impact of dental treatments under general anesthesia on oral health-related quality of life in children: a comprehensive meta-analysis by Nasibe Aycan Yilmaz, Mehmet Emin Arayici, Candan Efeoglu

Get full text

Assessment of Nutritional Status, Digestion and Absorption, and Quality of Life in Patients with Locally Advanced Pancreatic Cancer by J. E. Witvliet-van Nierop, C. M. Lochtenberg-Potjes, N. J. Wierdsma, H. J. Scheffer, G. Kazemier, K. Ottens-Oussoren, M. R. Meijerink, M. A. E. de van der Schueren

Get full text

Effects of Particulate Matter Exhaust on Functional Parameters of Organ Systems and Reactive Oxygen Species: A Cross-Sectional Study by Manjula Shivanagappa, SS Malini, Thanmayi Mahadeshwara Prasad, D. R. Mahadeshwara Prasad

Get full text

The efficacy of mindfulness-based interventions for patients with COPD: a systematic review and meta-analysis protocol by Li Li, Ying Wu, Ying Zhang, Lingyun Tian, Yinglan Li

Get full text

Impact of Preoperative Daytime Sleepiness and Insomnia on Therapy Adherence and Neurostimulation Amplitude in Unilateral Hypoglossal Nerve Stimulation by Pordzik J, Ludwig K, Ruckes C, Gouveris H

“…Johannes Pordzik,1,* Katharina Ludwig,1,* Christian Ruckes,2 Haralampos Gouveris1 1Department of Otolaryngology/Head and Neck Surgery & Sleep Medicine Center, University Medical Center Mainz, Mainz, 55131, Germany; 2Interdisciplinary Center for Clinical Trials, University Medical Center Mainz, Mainz, 55131, Germany*These authors contributed equally to this workCorrespondence: Haralampos Gouveris, Email haralampos.gouveris@unimedizin-mainz.deIntroduction: Average adherence to hypoglossal nerve stimulation (HGNS) therapy is more than 5 h/night. …”
Get full text

Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy by Xiaopeng Li, Yang Zhong, Pengyuan Qi, Daoming Zhu, Chenglong Sun, Nan Wei, Yang Zhang, Zhanggui Wang

Get full text

Electroacupuncture regulates ferroptosis to improve postoperative cognitive dysfunction in mice through mediating GRX1/GSK-3β/Nrf2 axis by Xiaqing Zhang, Afen Zhang, Rui Li, Mingna Jiao, Rou Wen, Rongzhi Zheng

“…Results: Our findings revealed that partial hepatectomy surgery impaired learning and memory ability of mice, promoted ferroptosis. inhibited GRX1 and inactivated GSK-3β/Nrf2 pathway. …”
Get full text

Controversies in the Application of AI in Radiology—Is There Medico-Legal Support? Aspects from Romanian Practice by Ana-Maria Ungureanu, Sergiu-Ciprian Matei, Daniel Malita

Get full text

Microscopic Observation of Proliferative Membranes in Fibrocontractive Retinal Disorders by Rino Frisina, Francesco Tessarolo, Ivan Marchesoni, Federico Piccoli, Emiliana Bonomi, Patrizio Caciagli, Edoardo Midena, Giandomenico Nollo

“…Sixty-nine specimens from 64 eyes of 64 consecutive patients were collected at surgery and subjected to a multilevel analysis by means of optical and electron microscopy. …”
Get full text

Pediatric pancreatic acinar cell carcinoma with a non-canonical BRAF-KMT2C fusion and a classic SND1-BRAF fusion: a case report and literature review by Yaqin Wang, Jiasi Zhang, Dimin Nie, Ai Zhang, Qun Hu, Aiguo Liu

“…A multidisciplinary treatment strategy integrating surgery, chemotherapy, and radiation therapy offers a promising precedent for improving therapeutic outcomes and prolonging survival in pediatric PACC cases.…”
Get full text

Crotonylation-Related Prognostic Model of Esophageal Squamous Cell Carcinoma Based on Transcriptome Analysis and Single-Cell Sequencing Analysis by Lin RY, Chen RP, Lin FQ

“…Ruo-Yang Lin,1 Ren-Pin Chen,1 Fu-Qiang Lin2 1Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 2Department of Thoracic Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of ChinaCorrespondence: Fu-Qiang Lin, Email linfq66@qq.comBackground: Crotonylation is an emerging lysine acylation modification implicated in various diseases, yet its role in esophageal squamous cell cancer (ESCC) is unexplored. …”
Get full text

Hydrogel-Based Innovations in Carpal Tunnel Syndrome: Bridging Pathophysiological Complexities and Translational Therapeutic Gaps by Venera Cristina Dinescu, Liviu Martin, Marius Bica, Ramona Constantina Vasile, Andrei Gresita, Marius Bunescu, Mihai Andrei Ruscu, Madalina Aldea, Alexandra Daniela Rotaru-Zavaleanu

Get full text

Tale of two zones: investigating the clinical outcomes and research gaps in peripheral and transition zone prostate cancer through a systematic review and meta-analysis by Pedro Oliveira, Robert G Bristow, Ananya Choudhury, Ashwin Sachdeva, Noel Clarke, Hitesh Mistry, Amin Ali, Thiraviyam Elumalai, BhanuPrasad Venkatesulu, Lauren Hekman, Esther Baena

Get full text

ASSOCIATION BETWEEN SENSORIAL OTOLITHIC DEFICIT AND HEARING LOSS IN CHILDREN by Constantin Guma, Cristian Marius Mârțu, Sebastian Cozma, Raluca Olariu, Luminița Rădulescu, Alexandru Stingheriu, Iustin Iațentiuc, Mădălina Georgescu, Violeta Necula, Oana Bitere-Popa

“…In severe and profound cases, vestibular assessment before cochlear implantation is crucial to detect potential vestibular damage and to suggest the implantation strategy by simultaneous or sequential surgery.…”
Get full text

Hodgkin Lymphoma at the Paediatric Oncology Unit of Gabriel Touré Teaching Hospital, Bamako, Mali: 5-Year Experience by B. Togo, F. Traoré, A. P. Togo, C. B. Traoré, K. Dumke, M. Diawara, A. A. Diakité, M. Sylla, F. Traoré-Dicko, B. Traoré, T. Sidibé

Get full text

Evaluation of root development of mandibular first molar of children (6-12) years old visiting P.O.P. department College of Dentistry/ Hawler Medical University. by Yara Ismail Ameen, Manal Muhammed Taher, Mahmood Fawzi Abduljabar

“… Background and objective: With FPMs between the ages of 6 and 12, the detection of open apex in some children at age 12 underlines the necessity for investigation prior to treating a deep carious lesion.Pulpal involvement was considered before the surgery began. The genesis of the roots is complete. …”
Get full text

Comparison of clinician- and patient-reported outcome measures in 95 abdominoplasty cases using BODY-Q and MCCRO-Q by Samuel Thomas Kitching, Claudia Rocco, Rachel Harwood, Gary Ross

“…Clinicians reported better outcomes in patients who achieved massive weight loss through diet and exercise as opposed to bariatric surgery (p=0.044). Patients who underwent concomitant surgical operation had significantly improved clinician-scored outcomes (p=0.047), and patients with post-operative complications achieved worse clinician-scored outcomes (p=0.036). …”
Get full text

Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat by John Garcia, Claire Mennan, Helen S. McCarthy, Sally Roberts, James B. Richardson, Karina T. Wright

“…Autologous chondrocyte implantation (ACI) is a cell-based therapy that has been used clinically for over 20 years to treat cartilage injuries more efficiently in order to negate or delay the need for joint replacement surgery. In this time, very little has changed in the ACI procedure, but now many centres are considering or using alternative cell sources for cartilage repair, in particular mesenchymal stem cells (MSCs). …”
Get full text

CD34 evaluation of microvasculature in lung adenocarcinoma and its microvascular density predicts postoperative tumor recurrence by Zijian Qiu, Jiaji Wu, Guanchao Pang, Xia Xu, Jun Lin, Pingli Wang

“…Thus, the detection of intratumoral MVD is of great significance for understanding disease progression and predicting patient prognosis.MethodsTumor tissue sections of 238 patients with lung adenocarcinoma (LUAD) who underwent radical surgery were retrospectively analyzed. Immunohistochemical (IHC) staining was carried out using a CD34 polyclonal antibody to determine intratumoral MVD, and the relationship of CD34-MVD with the clinicopathological characteristics and survival time of LUAD patients was analyzed.ResultsCD34-MVD was associated with tumor size, lymph node metastasis, tumor recurrence, and patient survival status; patients with tumor size ≤3 cm (P = 0.015), negative for lymph node metastasis (P = 0.049), no tumor recurrence (P = 0.021), and survival (P = 0.042) had higher MVD. …”
Get full text

Physical impairments in Adults with Developmental Dysplasia of the Hip (DDH) undergoing Periacetabular osteotomy (PAO): A Systematic Review and Meta-Analysis by Michael J M O'Brien, Julie S Jacobsen, Adam I Semciw, Inger Mechlenburg, Lisa U Tønning, Chris J W Stewart, Joshua Heerey, Joanne L Kemp

“…Compared to asymptomatic participants, patients with DDH demonstrate physical impairments during walking which appear to improve after surgery. Hip abduction and flexion strength did not change pre- to post-PAO…”
Get full text