Low Grade Islet but Marked Exocrine Pancreas Inflammation in an Adult with Autoimmune Pre-Diabetes by Hiroshi Nomoto, Tatyana Gurlo, Madeline Rosenberger, Mark D. Girgis, Sarah Dry, Peter C. Butler

“…We obtained pancreas from an individual with pre-T1D obtained at surgery and addressed the question, what is the relative inflammation in the exocrine and endocrine pancreas in pre-T1D in the absence of the potential confounding changes at autopsy or in brain dead organ donors. …”
Get full text

A Case of Primary Hyperparathyroidism due to Intrathyroidal Parathyroid Cyst by Yavuz Yalcin, Turkan Mete, Recep Aktimur, Gultekin Ozan Kucuk, Gulhan Duman, Aysu Basak Ozbalci, Omer Alici

Get full text

Immunotherapy of osteosarcoma based on immune microenvironment modulation by Heping Lian, Heping Lian, Jiakui Zhang, Shuna Hou, Shuang Ma, Jiachen Yu, Wei Zhao, Duoyi Zhao, Zhiyu Zhang

“…Osteosarcoma is a highly malignant tumor with unsatisfactory therapeutic outcomes achieved by chemotherapy, radiotherapy, and surgery. As an emerging oncological treatment, immunotherapy has shown potential in the clinical management of many tumors but has a poor response rate in osteosarcoma. …”
Get full text

Value of contrast-enhanced ultrasound in diagnosis of thrombus in inferior vena cava filter by ZHANG Jian, QIAN Weiqing, YI Xiaolei

Get full text

A Case of an Incidentally Removed Lingual Osseous Choristoma by Tomotaka Hemmi, Jun Suzuki, Satoko Sato, Masumi Tabata, Kojiro Watanabe, Mitsuru Sugawara, Yukio Katori

Get full text

Outcomes of Vitrectomy Combined with Scleral Buckling for Eyes with Early Recurrence of Simple Rhegmatogenous Retinal Detachment Previously Treated by Pars Plana Vitrectomy by Tomoaki Tatsumi, Takayuki Baba, Takehito Iwase, Tomohiro Nizawa, Gen Miura, Hirotaka Yokouchi, Shuichi Yamamoto

“…The significance of the associations between the variants before the surgeries and the final best-corrected visual acuity (BCVA) was determined. …”
Get full text

A Cell Differentiation Trajectory-Related Signature for Predicting the Prognosis of Lung Adenocarcinoma by Fan Yang, Yan Zhao, Xiaohan Huang, Jin Zhang, Ting Zhang

Get full text

Effects of kinesio taping in patients undergoing knee or hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials by Ting Mei, Yuli Shuai, Dandong Wu, Heping Yu

“…Outcomes for knee arthroplasty patients, included pain, oedema, range of motion, and the Hospital for Special Surgery knee score. For hip arthroplasty, the outcome focused on pain. …”
Get full text

Cell Therapy in Patients with Critical Limb Ischemia by Rita Compagna, Bruno Amato, Salvatore Massa, Maurizio Amato, Raffaele Grande, Lucia Butrico, Stefano de Franciscis, Raffaele Serra

Get full text

A large histological images dataset of gastric cancer with tumour microenvironment annotation for AI by Shenghan Lou, Jianxin Ji, Huiying Li, Xuan Zhang, Yang Jiang, Menglei Hua, Kexin Chen, Kaiyuan Ge, Qi Zhang, Liuying Wang, Peng Han, Lei Cao

Get full text

Cell Based Autologous Immune Enhancement Therapy (AIET) after Radiotherapy in a Locally Advanced Carcinoma of the Cervix by Sumana Premkumar, Vidyasagar Devaprasad Dedeepiya, Hiroshi Terunuma, Rajappa Senthilkumar, Thangavelu Srinivasan, Helen C. Reena, Senthilkumar Preethy, Samuel J. K. Abraham

“…However for residual disease in the form of the persistent lymph nodes, surgery or chemotherapy is recommended. As surgery is not acceptable by every patient and chemotherapy has associated side effects, we hereby report the positive outcome of in vitro expanded natural killer cell and activated T lymphocyte based autologous immune enhancement therapy (AIET) for the residual lymphadenopathy in a patient with locally advanced cervical cancer after radiation. …”
Get full text

Does Radar Technology Support the Diagnosis of Pneumothorax? PneumoScan—A Diagnostic Point-of-Care Tool by T. Lindner, M. Conze, C. E. Albers, B. A. Leidel, P. Levy, C. Kleber, M. De Moya, A. Exadaktylos, C. Stoupis

Get full text

Immune Checkpoint Blockade in Melanoma – Earlier is Better? by Vincas Urbonas, Audrius Dulskas, Edita Baltruškevičienė, Daiva Dabkevičienė

“… Administering checkpoint inhibition before surgery, known as neoadjuvant therapy, shows promise in treating bulky yet resectable melanomas, and researchers are investigating its potential in various other cancer types. …”
Get full text

Melanoma-derived cytokines and extracellular vesicles are interlinked with macrophage immunosuppression by Shankar Suman, Wendy K. Nevala, Alexey A. Leontovich, James W. Jakub, Liyi Geng, Sarah A. McLaughlin, Svetomir N. Markovic

Get full text

Expression of Otx Genes in Müller Cells Using an In Vitro Experimental Model of Retinal Hypoxia by Claudio Azzolini, Simone Donati, Giovanni Micheloni, Vittoria Moretti, Roberto Valli, Francesco Acquati, Lucy Costantino, Fulvio Ferrara, Davide Borroni, Elias Premi, Francesco Testa, Francesca Simonelli, Giovanni Porta

Get full text

Phthisis Bulbi in a Retinitis Pigmentosa Patient after Argus II Implantation by Logan Vander Woude, Ramak Roohipour, Gibran Syed Khurshid

“…The patient met the criteria for Argus II implantation and elected to proceed with surgery in his left eye in December 2017. The surgical implantation of the Argus II was successful without any complications. …”
Get full text

Clinical Presentation and Course of Crohn's Disease in Southeastern Ontario by William T. Depew, Jose Medeiros, Ivan T. Beck, Laurington R. Dacosta, Aubrey Groll

“…The frequency of complications and the necessity for surgery were similar to other reported series. None of the patients had either large or small bowel cancer during the follow-up period and there were no deaths related directly to Crohn's disease, its complications or related surgery.…”
Get full text

A Dilemma in Staging of Esophageal Cancer: How Should We Stage ypT0 N2 M0 Esophageal Cancer after Neoadjuvant Therapy? by Sebahattin Celik, Remzi Erten, Abdulsamed Batur, Burak Suvak

“…Six weeks after neoadjuvant therapy, with a curative intention, minimal invasive surgery was performed. The pathology report was as follows. …”
Get full text

Air Bubble Technique for Fundus Visualization during Vitrectomy in Aphakia by Mahmoud Mohamed Farouk, Takeshi Naito, Mohammed Elagouz, Hatem Ammar, Alahmady Hamad Alsmman, Engy Mohamed Mostafa

“…Cases with complicated vitreoretinal pathology were not included in this study. All vitrectomy surgeries were conducted by the air bubble technique in the anterior chamber. …”
Get full text

A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis by Lauro L. Abrahan IV, Stephanie Martha O. Obillos, Jaime Alfonso M. Aherrera, Jose Donato A. Magno, Celia Catherine C. Uy-Agbayani, Ulysses King G. Gopez, Jobelle Joyce Anne R. Baldonado

Get full text