A Rare Case of Post-Partum Hemorrhage with Refractory Thrombotic Microangiopathy, and Hepatic Infarction: A Diagnostic Dilemma with High Mortality by Naved Yousuf Hasan, Asiah Salem Rugaan, Noha Ahmed Mohamed Ali, Masood Iqbal

“…The patient required continuous renal replacement therapy and high supportive care. She stayed in the intensive care unit for 9 days, developed multi-organ failure, and finally expired. …”
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Severe Aplastic Anemia following Acute Hepatitis from Toxic Liver Injury: Literature Review and Case Report of a Successful Outcome by Kamran Qureshi, Usman Sarwar, Hicham Khallafi

“…The liver injury slowly resolved with supportive care and after 4 months of attack of AH, he developed SAA. …”
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Drug-induced Leukocytoclastic Vasculitis Secondary to Trimethoprim/Sulfamethoxazole: A Case Report by Ambika Shivarajpur, Simon Londono, Justin Shaw, Christopher Boccio, Leonid Melnitsky, Jheanelle McKay, Brian Kohen, Eric Boccio

“…Conclusion: Most cases of LCV are limited to cutaneous symptoms and self-resolve with supportive care.…”
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Ethical challenges in palliative sedation of adults: protocol for a systematic review of current clinical practice guidelines by Cécile Jaques, Ralf J Jox, Martyna Tomczyk

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Pain catastrophizing is associated with high-dose opioids in patients with cancer pain by Simon van Rysewyk, Melanie Lovell, Paul Glare

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Cost-effectiveness Analysis of Radium-223 Dichloride in Metastatic Castration-Resistant Prostate Cancer Patients Without Previous Chemotherapy Treatment in Spain by Eva Tirado Mercier, Daniel Callejo Velasco, Marta Rubio Cabezas, Cristina Moretones Agut, Meritxell Granell Villalón

“…**Purpose:** To perform a cost-effectiveness analysis of radium-223 plus Best Supportive Care (BSC) compared to BSC in the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) and without previous docetaxel treatment in Spain. …”
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Asymptomatic Pulmonary Artery Intimal Sarcoma with Chest Wall Metastasis as an Initial Manifestation: An Autopsy Case by Tomoo Kakimoto, Mamoru Sasaki, Shojiroh Morinaga, Robert Nakayama, Naoto Minematsu

“…He was scheduled to receive supportive care, but died of respiratory failure 1 year from the first visit. …”
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A 5-Fluorouracil-Induced Hyperammonemic Encephalopathy Challenged with Capecitabine by Michael Chahin, Nithya Krishnan, Hardik Chhatrala, Marwan Shaikh

“…During her evaluation, she was found to have hyperammonemia (84 mcmol/L), without hepatic failure, that resolved with stopping chemotherapy and supportive care. After a trial of home infusion fluorouracil, she developed hyperammonemic encephalopathy again. …”
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A Case of Reverse Takotsubo Cardiomyopathy Incited by a Spinal Subdural Hematoma by Kyle Sanchez, Steven Glener, Nathan E. Esplin, Okorie N. Okorie, Amay Parikh

“…Repeated echocardiogram demonstrated an EF of 20-25% with a reverse Takotsubo pattern of cardiomyopathy. With supportive care, his clinical picture improved with normalization of cardiac enzyme and BNP values. …”
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Rapid Glomerulotubular Nephritis as an Initial Presentation of a Lethal Diquat Ingestion by Daniel Guck, Reynaldo Hernandez, Steven Moore, Andry Van de Louw, Philippe Haouzi

“…Progressive multiorgan system failure then developed with a significant delay (24–38 hours) including acute renal, liver failure, and then respiratory failure with refractory hypoxemia. Despite maximal supportive care, the end organ failure was lethal. Discussion. …”
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Outcomes of Treatment for Melanoma Brain Metastases by Mantas Janavicius, Nadezda Lachej, Giedre Anglickiene, Ieva Vincerzevskiene, Birute Brasiuniene

“…The shortest survival was observed in the best supportive care group and patients treated by systemic therapy only. …”
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Fat Embolism and Nonconvulsive Status Epilepticus by Yanetsy Olivera Arencibia, Mai Vo, Jennifer Kinaga, Jorge Uribe, Gloria Velasquez, Mario Madruga, S. J. Carlan

“…The diagnosis is clinical and is treated with supportive care, antiepileptic therapy, and sedation. …”
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Fludarabine/Cyclophosphamide Conditioning Regimen in Aplastic Anemia Patients Receiving Matched-Sibling Donor Transplant Is Non-inferior to ATG/Cyclophosphamide: A Single-Center Ex... by Uzma Zaidi, Mushkbar Fatima, Shafaq Abdul Samad, Kashif Shafique, Hira Fatima Waseem, Tasneem Farzana, Tahir Sultan Shamsi

“…The successful outcome of allogeneic hematopoietic stem cell transplant (HSCT) in aplastic anemia patients is driven by suitable donor selection, appropriate conditioning regimen, early intervention, and optimal supportive care after transplant. Pakistan, being a developing country, faces grave economic challenges due to meager health care budget; therefore, cost constraints remain the foremost impediment in optimizing transplant facilities for socioeconomically deprived patients. …”
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The Experience of Melanoma Follow-Up Care: An Online Survey of Patients in Australia by Janine Mitchell, Peta Callaghan, Jackie Street, Susan Neuhaus, Taryn Bessen

“…Focus on strategies for greater consistency in the provision of support, information, and investigations received, may generate a cost dividend which could be reinvested in preventive and supportive care and benefit patient well-being.…”
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Successful Treatment of Cisplatin Overdose with Plasma Exchange by Yasuhiro Yamada, Yoshiaki Ikuta, Kisato Nosaka, Nobutomo Miyanari, Naoko Hayashi, Hiroaki Mitsuya, Hideo Baba

“…Here, we report a case of large cisplatin overdose, successfully managed by plasma exchange, intravenous hydration, granulocyte colony-stimulating factor (G-CSF) administration, and other supportive care. A 67-year-old man with esophageal carcinoma received a large cisplatin overdose of 240 mg/m2, when he received adjuvant therapy following subtotal esophagectomy. …”
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Diagnostic Challenge in a Patient with Severe Anion Gap Metabolic Acidosis by Eugene M. Tan, Ejaaz Kalimullah, M. Rizwan Sohail, Kannan Ramar

“…After 5 days in the intensive care unit (ICU), her mental status improved with supportive care. She was discharged to a nursing facility. …”
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Pathophysiological mechanisms, multidimensional diagnostics and modern therapies of pruritus in pancreatic cancer: review and perspectives by Jagienka Agata Włodyka, Urszula Zelik, Maria Przygoda, Wiktoria Domino, Gabriela Trestka, Sabina Adamczyk, Kamila Stępień, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Jakub Dziewic

“…Lastly, a comprehensive therapeutic approach is addressed, consisting of causal treatment, pharmacological interventions, and supportive care. …”
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Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review by Maria Eleonora Bizzoca, Stefania Leuci, Michele Davide Mignogna, Eleonora Lo Muzio, Vito Carlo Alberto Caponio, Lorenzo Lo Muzio

“…To date, excluding the possibility of vaccination, against SARS-CoV-2 infection it is possible to act only with supportive care and non-virus-specific treatments in order to improve the patient's symptoms. …”
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A three dimensional printed endobronchial stent for the treatment of a broncho-esophageal fistula by Illaa Smesseim, Sophia van Beelen, Jolanda M. van Dieren, Koen J. Hartemink, Johanna van Sandick, Jacobus A. Burgers

“…Despite dual stenting with a custom 3D airway stent, the fistula persisted, and the patient was transitioned to supportive care due to disease progression. This case, the first to use a 3D-printed airway stent for a broncho-esophageal fistula, demonstrates that the stent did not achieve closure, likely due to excessive pressure against the endobronchial wall. …”
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Advances in antiviral strategies targeting mosquito-borne viruses: cellular, viral, and immune-related approaches by Ayyaz Khan, Zakirullah, Shahid Wahab, Seong-Tshool Hong

“…Despite extensive research, effective antiviral treatments for MBVs remain scarce, and current therapies mainly provide symptomatic relief and supportive care. This review examines the viral components and cellular and immune factors involved in the life cycle of MBVs. …”
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