Efficacy of Functional Endoscopic Sinus Surgery and Impact of Chronic Lung Disease on its Outcome in Patients of Chronic Rhinosinusitis by Minakshmi Karmakar, V D Prasanna Kumar Vasamsetty, Bonapart Chowdhury

“…Functional Endoscopic Sinus Surgery (FESS) has gained acceptance throughout the world as a procedure believed to improve the symptoms of chronic rhinosinusitis and consequently the general wellbeing of patients suffering from the condition. Patients with CRS are also known to have comorbidities. …”
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miR-10a in Peripheral Blood Mononuclear Cells Is a Biomarker for Sepsis and Has Anti-Inflammatory Function by Guoping Zheng, Guanguan Qiu, Menghua Ge, Jianbiao Meng, Geng Zhang, Jiangmei Wang, Ruoqiong Huang, Qiang Shu, Jianguo Xu

“…A total of 62 patients (41 with sepsis and 21 with infection suffering from pneumonia but without sepsis) and 20 healthy controls were enrolled into the study. …”
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Identification and functional analysis of a novel SMARCC2 splicing variant in a family with syndromic neurodevelopmental disorder by Ming Li, Jingqi Lin, Hongjun Fei, Jinyu Liu, Yiyao Chen, Xu Han, Yanlin Wang, Jian Wang, Renyi Hua, Shuyuan Li, Niu Li

“…Conclusion We identified and reported a pair of twins suffering from syndromic neurodevelopmental disorders caused by a novel splicing variant of SMARCC2. …”
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Diagnosis and management of type 2 diabetes mellitus in patients with ischaemic heart disease and acute coronary syndromes - a review of evidence and recommendations by Muhammad Usman Shah, Muhammad Usman Shah, Alun Roebuck, Bala Srinivasan, Joanna Kate Ward, Paul Edward Squires, Claire Elizabeth Hills, Kelvin Lee, Kelvin Lee

“…The estimated number of individuals suffering from diabetes mellitus (DM) is expected to rise to 591 million by the year 2035 with 4.4 million in the United Kingdom (UK) alone, 90% of which is attributed to T2DM. …”
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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…This still represents a significant societal burden and these findings may help inform public health initiatives to encourage prevention and evidence‐based interventional strategies and ultimately, improve the quality of life for those suffering with SP in Wales.…”
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Association of social frailty, sarcopenia, and oral frailty with depressive symptoms in Chinese older adults: a cross-sectional study by Yuanhao Sun, Huan Liu, Xiangdong Li, Lin Zhang, Wenwen Xu, Hairong liu, Ting Yuan

“…Abstract Background Depressive symptoms are a serious health issue that can cause profound, lifelong suffering for people who are affected by it. This study aimed to evaluate the effect of sarcopenia, oral frailty, and social frailty on depressive symptoms among Chinese participants aged ≥ 60 years old in China. …”
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Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic live... by Nikolina Canová, Jana Šípková, Mahak Arora, Zuzana Pavlíková, Zuzana Pavlíková, Tomáš Kučera, Ondřej Šeda, Tijana Šopin, Tomáš Vacík, Ondřej Slanař

“…Therefore, this study aimed to investigate the effects of celastrol on the galaninergic system expression in the heart and liver of mice suffering from diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis (MASLD/MASH).MethodsThe male mice C57BL/6J were fed a Western-type high-fat diet for 16 and 20 weeks to induce obesity and MASLD/MASH. …”
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Association of epidural labor analgesia with maternal and neonatal outcomes in women with preeclampsia: a propensity score-matched single-center retrospective cohort study by Xi-Zhu Wu, Tuan-Fang Fang, Yi-Han Zheng, Su-Jing Zhang, Yi Xie, Xiang Gao, Guo-Lin Lu

“…However, it remains unclear whether ELA affects maternal and neonatal outcomes in women suffering from preeclampsia. Methods This study reviewed the medical records of women with preeclampsia at ≥ 28 weeks of gestation between January 2015 and December 2020. …”
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April 15th war and hemodialysis patients in Sudan: a cross-sectional study by Malaz Hassan Dafaalla Idrees, Moez Mohammed Ibrahim Bashir, Balqees Abdeen Ahmed Mohamed, Amal Essam Ali Ahmed, Hamid Mohieldin Mohamed Abdalla, Kamil Mirghani Ali Shaaban

“…Conclusion Hemodialysis patients’ suffering has increased as a result of the war. Hemodialysis patients experience severe mental health problems in addition to physiological problems, including depression and anxiety, as a result of internal displacement and their inability to continue regular hemodialysis sessions. …”
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Using the Oxford Foot Model to determine the association between objective measures of foot function and results of the AOFAS Ankle-Hindfoot Scale and the Foot Function Index: a pr... by Frank Krummenauer, Tanja Kostuj, Felix Stief, Kirsten Anna Hartmann, Katharina Schaper, Mohammad Arabmotlagh, Mike H Baums, Andrea Meurer, Sebastian Lieske

“…Furthermore, factor analysis did not support stratification of the FFI-D into two subscales.Conclusions The AOFAS-AHS showed a good agreement with objective gait parameters and is therefore better suited to evaluate disability and functional limitations of patients suffering from foot and ankle pathologies compared with the FFI-D.…”
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Single or multiple treatments with lusutrombopag in subjects with thrombocytopenia and chronic liver disease needing an invasive procedure by Davide Scalabrini, Paolo Sciuto, Cristina Felicani, Antonia Rudilosso, Pietro Andreone

“…This article reports two different cases concerning respectively an 83-year-old female patient suffering from arterial hypertension, aneurysm of the sub-renal aorta, hepatitis C virus (HCV)-positive liver cirrhosis responsive to treatment with antiviral drugs, and a 2.0 cm diameter hepatocellular carcinoma (HCC) nodule localized in the hepatic segment III and a 53-year-old female patient with HCV-positive liver cirrhosis complicated by portal hypertension with splenomegaly, thrombocytopenia, and F3 esophageal varices at high risk of bleeding. …”
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Sacubitril/valsartan on right ventricular-pulmonary artery coupling and albumin-bilirubin score in heart failure in Chinese patients with reduced ejection fraction by Yanan Shi, Chuanyu Gao, Yu Xu, Fang Yuan

“…Abstract Objective Impaired right ventricular (RV)-pulmonary arterial (PA) coupling, calculated by measuring the tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (PASP), can be used as an early indicator of right ventricular dysfunction (RVD) in patients with heart failure with a reduced ejection fraction (HFrEF). Patients suffering from HFrEF experience improvements in left ventricular (LV) function through the administration of sacubitril/valsartan therapy. …”
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Foxtail millet supplementation improves glucose metabolism and gut microbiota in rats with high-fat diet/streptozotocin-induced diabetes by Xin Ren, Linxuan Wang, Zenglong Chen, Min Zhang, Dianzhi Hou, Yong Xue, Xianmin Diao, Ruihai Liu, Qun Shen

“…Our findings provide further support that consuming more whole-grain FM might be beneficial to individuals suffering from type 2 diabetes.…”
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Socio-economic assessment of drought impacts in Lesotho: implications for early action by Relebohile Agnes Mojaki, Makoala Vitalis Marake, Evan Easton-Calabria, Joalane Rethabile Marunye, Erin Coughlan de Perez

“…This study aims to ask: what are people’s experiences of drought and potential early actions that could save livelihoods and reduce human suffering? Design/methodology/approach – A qualitative research approach was adopted where this paper carried out consultations in three agroecological zones, i.e. …”
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Sistem Pakar Diagnosa Penyakit Campak Rubella pada Anak Menggunakan Metode Certainty Factor Berbasis Website by Pujianti Wahyuningsih, Sitti Zuhriyah

“…The result of this study is when the CF value is >=0.8, and then the system will diagnose the patient is suffering from rubella measles disease. When the CF value is <0.8 and >=0.4 then the system diagnose the patient probably suffer the rubella measles disease, and then when the CF value is <0.4 then the system will diagnose the patient is not hurting the rubella measles disease. …”
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Automated AI-based image analysis for quantification and prediction of interstitial lung disease in systemic sclerosis patients by Julien Guiot, Monique Henket, Fanny Gester, Béatrice André, Benoit Ernst, Anne-Noelle Frix, Dirk Smeets, Simon Van Eyndhoven, Katerina Antoniou, Lennart Conemans, Janine Gote-Schniering, Hans Slabbynck, Michael Kreuter, Jacobo Sellares, Ioannis Tomos, Guang Yang, Clio Ribbens, Renaud Louis, Vincent Cottin, Sara Tomassetti, Vanessa Smith, Simon L. F. Walsh

“…Results We evaluated a group of 75 patients suffering from SSc-ILD, either limited or diffuse, of whom 30 presented progressive pulmonary fibrosis (PPF). …”
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Is Intra-articular Platelet-rich Plasma Injection Safe and Effective in Osteoarthritis Knee? A Prospective Study: A Case Series by R Sahaya Jose, N Kattu Bava, M Syed Moosa

“…In total, 30 patients of either sex, between 40 and 70 years of age, suffering from primary knee OA with Kellgren–Lawrence (KL) grades I, II, or III on standing anteroposterior and lateral knee radiographs, with symptoms for >3 months according to the American College of Rheumatology (ACR) clinical classification criteria and pain score of >4 cm on 10 cm visual analog scale (VAS) was included. …”
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Phantom motor execution as a treatment for phantom limb pain: protocol of an international, double-blind, randomised controlled clinical trial by Brian E McGuire, Lina Bunketorp-Käll, Eva Lendaro, Liselotte Hermansson, Helena Burger, Corry K Van der Sluis, Monika Pilch, Katarzyna Kulbacka-Ortiz, Ingrid Rignér, Anita Stockselius, Lena Gudmundson, Cathrine Widehammar, Wendy Hill, Sybille Geers, Max Ortiz-Catalan

“…Here we present the study protocol for an international (seven countries), multicentre (nine clinics), double-blind, randomised controlled clinical trial to assess the effectiveness of PME in alleviating PLP.Methods and analysis Sixty-seven subjects suffering from PLP in upper or lower limbs are randomly assigned to PME or phantom motor imagery (PMI) interventions. …”
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The effects of TECAR therapy on pain, range of motion, strength and subscale of HAGOS questionnaire in athletes with chronic adductor related groin pain: a randomized controlled tr... by Sara Nazari, Soheil Mansour Sohani, Javad Sarrafzadeh, Hooman Angoorani, Abbas Tabatabaei

“…The objective of the present study is to explore the effect of TECAR therapy on pain, range of motion (ROM), strength, and subscales of the "Copenhagen Thigh and Groin Assessment Scale"(HAGOS) questionnaire in athletes suffering from adductor-related groin pain (ARGP). …”
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Signatures of H3K4me3 modification predict cancer immunotherapy response and identify a new immune checkpoint-SLAMF9 by Tao Fan, Chu Xiao, Ziqin Deng, Shuofeng Li, He Tian, Yujia Zheng, Bo Zheng, Chunxiang Li, Jie He

“…Importantly, this risk-score system showed satisfactory predictive performance for the ICB therapy responses of patients suffering from several cancer types, and we identified that SLAMF9 was one of the immunosuppressive phenotype and immunotherapy resistance-determined genes of H3K4me3-RS. …”
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