Cutaneous amyloidosis in the orbital region (case report) by A.N. Bochkareva, V.V. Egorov, O.V. Kolenko, G.P. Smolyakova, P.A. Banshchikov

“…Insufficient awareness of the disease, due, among other things, to the extremely low incidence of patients with amyloidosis — today about 50 thousand people suffer from amyloidosis in the world. The article presents a clinical case of the early stage of primary systemic AL-amyloidosis affecting the eyelid skin bilaterally with further disease progression involving the skin of palms, soles and the oral mucosa. …”
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Cerebral Cortical Activity During Academic Stress Amongst Undergraduate Medical Students at Kampala International University (Uganda) by Mujinya, Regan, Kalange, Muhamudu, Ochieng, Juma John, Ninsiima, Herbert Izo, Eze, Ejike Daniel, Afodun, Adam Moyosore, Nabirumbi, Ritah, Sulaiman, Sheu Oluwadare, Kairania, Emmanuel, Echoru, Isaac, Okpanachi, Alfred Omachonu, Matama, Kevin, Asiimwe, Oscar Hilary, Nambuya, Grace, Usman, Ibe Michael, Obado, Osuwat Lawrence, Zirintunda, Gerald, Ssempijja, Fred, Nansunga, Miriam, Matovu, Henry, Ayikobua, Emmanuel Tiyo, Nganda, Ponsiano Ernest, Onanyang, David, Ekou, Justine, Musinguzi, Simon Peter, Ssimbwa, Godfrey, Keneth Iceland, Kasozi

“…Conclusion: Preclinical students suffer more from stress and are poorer SS than clinical students. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…Indeed, the sample is based on people who go to hospitals or suffer symptoms, most of the time already severe. …”

Incidence and prevalence of traumatic and non-traumatic wounds and burns and access to wound care in Sierra Leone; data from a nationwide household survey (PRESSCO) 2020 by Jonathan H. Vas Nunes, Alex J. van Duinen, Daniel Boateng, Amidu J. Tommy, Osman Sankoh, Martin P. Grobusch, Håkon A. Bolkan

“…An estimated 44,000 (95 % CI 29,760–67,410) people in Sierra Leone suffer from a severe wound. An estimated 11,000 (95 % CI 6,416–18,268) annual deaths occur due to wounds, predominantly due to RTA's (66.7 %) and accidental injuries (20.0 %). …”
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Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Stu... by Haobin Peng, Jiajun Wen, Manli Chen, Zhengyuan Xia, Ying Jiang, Kaiqi Xie, Weitao Huang, Bangsheng Cui, Peixing Li, Yiwen Zhang, Xianping Wu

“…Abstract Introduction Single-injection pericapsular nerve group (PENG) block with ropivacaine provides clear analgesic effects in preoperative pain management for hip fractures. However, it suffers from insufficient duration, failing to meet the needs of most patients. …”
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Effectiveness of a specialist palliative home care nurse–patient consultation followed by an interprofessional telephone case conference compared with usual care among patients wit... by Judith Dams, Hans-Helmut König, Tim Friede, Nils Schneider, Stephanie Stiel, Martin Scherer, Silke Böttcher, Gabriella Marx, Ingmar Schäfer, Nadine Janis Pohontsch, Hendrik van den Bussche, Friedemann Nauck, Michael Freitag, Eva Hummers, Tina Mallon, Franziska Schade, Manuel Zimansky, Thomas Asendorf, Christiane A Mueller

“…Most of these patients suffer from severe symptoms, reduced quality of life and increased numbers of hospitalisations. …”
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Case report: Successful treatment of hyperbaric oxygen for radiation-induced hemorrhagic cystitis in a 95-year-old patient with bladder cancer by Li Lin, Li Lin, Man He, Yanyan Zeng, Xiaoxiao Ni, Yequn Guo, Xiaojuan Xie, Lingling Sun, Huai Huang

“…However, there is a lack of reported data addressing the applicability of HBOT in very elderly patients (over 90 years old) with severe bleeding necessitating multiple blood transfusions.Case presentationThe patient is a 95-year-old male who suffered from severe hematuria due to RHC after 33 sessions of radiotherapy for muscle-invasive bladder cancer (T2N0M0, stage: II). …”
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A Physics-Based Hyper Parameter Optimized Federated Multi-Layered Deep Learning Model for Intrusion Detection in IoT Networks by Chirag Jitendra Chandnani, Vedik Agarwal, Shlok Chetan Kulkarni, Aditya Aren, D. Geraldine Bessie Amali, Kathiravan Srinivasan

“…Multiple client models collaboratively train a global model while keeping the individual client’s data decentralized and private. This, however, suffers from poor generalization of the individual client data. …”
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Simultaneous non-contrast assessment of cardiac microstructure and perfusion in vivo in the human heart by Camila Munoz, Eunji Lim, Pedro F. Ferreira, Dudley J. Pennell, Sonia Nielles-Vallespin, Andrew D. Scott

“…However, the spin echo-based approaches typically used for cardiac IVIM suffer from low sensitivity to changes in perfusion. …”
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Dietary diversity and its associated factors among school children in conflict affected communities of southern Ethiopia by Tagese Yakob, Eskinder Israel, Begidu Yakob, Mekdes Meshesha, Endale Jambo, Tadewos Utalo, Awoke Abraham

“…BackgroundGlobally, more than 815 million estimated people worldwide suffer from malnutrition or are unable to access enough food due to malnutrition. …”
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Towards water-conscious green hydrogen and methanol production: A techno-economic review by Henrik Wenzel, Gian Müller, Freia Harzendorf, Thomas Schöb, Felix Kullmann, Jann Michael Weinand, Detlef Stolten

“…Finally, the water-conscious and green production of hydrogen and methanol will make the energy transition more sustainable, and regions that are abundant in renewable energy sources but suffer from water-scarcity will also be able to participate.…”
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Curcumin encapsulated in PAMAM dendrimers for the therapeutic treatment of ischemic stroke in rats by Justin Stadler, Justin Stadler, Justin Stadler, Lucas G. Garmo, Lucas G. Garmo, Lucas G. Garmo, David Doyle, David Doyle, David Doyle, Chin-I. Cheng, Garrett Richardson, Garrett Richardson, Zain Waheed, Zain Waheed, Tim Tofan, Bhairavi Srinageshwar, Bhairavi Srinageshwar, Bhairavi Srinageshwar, Ajit Sharma, Robert B. Petersen, Gary L. Dunbar, Gary L. Dunbar, Gary L. Dunbar, Julien Rossignol, Julien Rossignol, Julien Rossignol

“…Curcumin is known to have anti-inflammatory and antioxidant effects yet suffers from poor solubility and bioavailability. …”
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MSCPNet: A Multi-Scale Convolutional Pooling Network for Maize Disease Classification by Mehdhar S. A. M. Al-Gaashani, Reem Alkanhel, Muthana Ali Salem Ali, Mohammed Saleh Ali Muthanna, Ahmed Aziz, Ammar Muthanna

“…Traditional CNN-based models, while effective in extracting spatial features, often fail to capture subtle multi-scale variations necessary for distinguishing between disease symptoms. These models also suffer from high computational complexity when deeper layers are introduced to handle fine-grained details. …”
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Anticancer Peptides Classification Using Long-Short-Term Memory With Novel Feature Representation by Nazer Al Tahifah, Muhammad Sohail Ibrahim, Erum Rehman, Naveed Ahmed, Abdul Wahab, Shujaat Khan

“…Existing techniques either suffer from low accuracy or employ high-dimensional feature sets, frequently producing sparse features and leading to ineffective model designs. …”
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Murine model of cross-IgE sensitization and cross-anaphylactic reactions among multiple group food allergens by Ibrahim Musa, Fariba Ardalani, Nan Yang, Soheila J. Maleki, Xiu-Min Li, Xiu-Min Li, Xiu-Min Li

“…RationaleApproximately 32 million people in the United States suffer from food allergies. Some food groups, such as legumes – peanuts, tree nuts, fish, and shellfish, have a high risk of cross-reactivity. …”
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Cutting-edge Bioinformatics strategies for synthesizing Cyclotriazadisulfonamide (CADA) analogs in next-Generation HIV therapies by Jay Gabriel B. Larga, Wrynan T. Munabirul, Abu Tayab Moin, Md Maisum Sarwar Jyoti, Mst Sanjida Nasrin, Minhaz Abdullah Al Mueid, Abdul Ahad, Anwar Parvez, Mst Sabrina Yeasmin, Rupali M. Barhate, Rajesh B. Patil, Margel C. Bonifacio

“…One proposed mechanism for CADA’s inhibition of the CD4 receptor involves blocking the gates of the Sec61 channel, thereby preventing its translocation. However, CADA suffers from poor solubility and bioavailability. …”
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Fibroblast growth factor 21 predicts arteriovenous fistula functional patency loss and mortality in patients undergoing maintenance hemodialysis by Xinhui Hu, Hong Ding, Qing Wei, Ruoxin Chen, Weiting Zhao, Liqiong Jiang, Jing Wang, Haifei Liu, Jingyuan Cao, Hong Liu, Bin Wang

“…Patients with higher serum levels of FGF21 were more likely to suffer from all-cause mortality (per 1 pg/mL increase, HR 1.002 [95% CI: 1.000–1.003, p = 0.014]). …”
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Endothelial and neuronal engagement by AAV-BR1 gene therapy alleviates neurological symptoms and lipid deposition in a mouse model of Niemann-Pick type C2 by Charlotte Laurfelt Munch Rasmussen, Signe Frost Frederiksen, Christian Würtz Heegaard, Maj Schneider Thomsen, Eva Hede, Bartosz Laczek, Jakob Körbelin, Daniel Wüstner, Louiza Bohn Thomsen, Markus Schwaninger, Ole N. Jensen, Torben Moos, Annette Burkhart

“…Abstract Background Patients with the genetic disorder Niemann-Pick type C2 disease (NP-C2) suffer from lysosomal accumulation of cholesterol causing both systemic and severe neurological symptoms. …”
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Effects of Semaglutide Treatment on Psoriatic Lesions in Obese Patients with Type 2 Diabetes Mellitus: An Open-Label, Randomized Clinical Trial by Jelena Petković-Dabić, Ivana Binić, Bojana Carić, Ljiljana Božić, Sanja Umičević-Šipka, Nataša Bednarčuk, Saša Dabić, Mirna Šitum, Snježana Popović-Pejičić, Miloš P. Stojiljković, Ranko Škrbić

“…Estimates are that approximately 2–3% of the world’s population suffers from this disease. More severe forms of psoriasis are conditions of high inflammation, which is confirmed by the clinical picture and numerous inflammatory parameters such as C-reactive protein (CRP), cytokines and homocysteine, which vary with disease activity. …”
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Combined Transplantation of Adipose Tissue-Derived Stem Cells and Endothelial Progenitor Cells Improve Diabetic Erectile Dysfunction in a Rat Model by Qiyun Yang, Wanmei Chen, Chi Zhang, Yun Xie, Yong Gao, Cuncan Deng, Xiangzhou Sun, Guihua Liu, Chunhua Deng

“…Erectile dysfunction (ED) is a common complication in men suffered with diabetic mellitus. Stem cell transplantation is a promising strategy for the treatment of diabetic ED (DED). …”
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