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19181
Russian Science Foundation grant No. 20-14-00140 supported this study. The authors are thankful to the multi-access Center “Bioinformatics” for the use of computational resources a...
Published 2023-01-01“…Besides, the palatability of plant foods and their health benefits could also be subjected to selection by humans in the past. Nonetheless, it is unclear whether in antiquity, aside from positive selection for beneficial properties of plants, humans simultaneously selected against such detrimental properties as allergenicity. …”
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19182
Genotype Variations and Association between PAI-1 Promoter Region (4G/5G and -844G/A) and Susceptibility to Acute Myocardial Infarction and Chronic Stable Angina
Published 2021-01-01“…It included 100 patients with AMI and stable angina and 100 healthy controls. All study subjects were typed for two PAI polymorphisms (4G/5G and -844G/A) through PCR-RFLP and level of PAI through ELISA. …”
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19183
Association between migraine severity and sleep quality: a nationwide cross-sectional study
Published 2025-01-01“…MIDAS was also significantly positively correlated with the following PSQI components: subjective sleep quality (p = 0.047), sleep latency (p < 0.001), sleep disturbance (p < 0.001), and daytime dysfunction (p < 0.001).ConclusionThese findings suggest a notable correlation between poor sleep quality and increased migraine severity, emphasizing the importance of addressing sleep disturbance as a potential strategy to mitigate migraine severity and improve patient outcomes.…”
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19184
Repeated social defeat in male mice induced unique RNA profiles in projection neurons from the amygdala to the hippocampus
Published 2025-02-01“…These AAV2rg-RiboTag mice were subjected to RSD and ribosomal-bound mRNA was collected from the amygdala for RNA-sequencing. …”
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19185
Lower Circulating miR-122 Level in Patients with HNF1A Variant-Induced Diabetes Compared with Type 2 Diabetes
Published 2018-01-01“…In total, 12 HNF1A-DM patients, 24 gender-, age-, and body mass index-matched (1 : 2) T2DM patients and 24 healthy subjects were included in this study. In addition, 30 monogenic diabetes (11 GCK-DM and 19 MDM) and 17 T1DM patients were included. …”
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19186
Hypothyroidism impairs the circadian rhythmicity of clock genes and proteins involved in gut nutrient absorption in female mice
Published 2025-01-01“…Adult female C57BL/6J mice were subjected to hypothyroidism by the administration of methimazole (0.1%) and sodium perchlorate (1%) in drinking water for 45 days. …”
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19187
Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats
Published 2025-01-01“…To investigate the beneficial effect of relaxin 2 on oxidative stress injury and neuronal apoptosis by GMH, a total of 150 rat pups were subjected to GMH by an intraparenchymal injection of bacterial collagenase. …”
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19188
Low Expression of FFAR2 in Peripheral White Blood Cells May Be a Genetic Marker for Early Diagnosis of Acute Myocardial Infarction
Published 2020-01-01“…Analyzing clinical data of the subjects indicated that the average age of the AMI group was significantly higher than the age of control group (p<0.01). …”
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19189
Three-year course of clinical high-risk symptoms for psychosis in the community: a latent class analysis
Published 2025-01-01“…Class 1 was mainly characterized by subtle, subjectively experienced disturbances in mental processes, including thinking, speech and perception (basic symptoms [BSs]). …”
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19190
Core microbe Bifidobacterium in the hindgut of calves improves the growth phenotype of young hosts by regulating microbial functions and host metabolism
Published 2025-01-01“…Abstract Background The growth and health of young ruminants are regulated by their gut microbiome, which can have lifelong consequences. Compared with subjective grouping, phenotypic clustering might be a more comprehensive approach to revealing the relationship between calf growth state and core gut microbes. …”
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19191
Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019
Published 2025-01-01“…Moreover, motivators and barriers for the application of preventive behaviour should be subject of future studies.…”
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19192
Semen Analysis of Covid-19 Survivors and Uninfected Men: Examining the Motility, Concentration, Vitality, and Morphology Parameters of Spermatozoa
Published 2024-09-01“…This study was an analytical observational study with a cross-sectional design. Subjects were selected through consecutive sampling of up to 26 men of childbearing age who met the predetermined criteria. …”
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19193
Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway
Published 2019-01-01“…The aim of this study was to investigate the effect of PAME on human BM-MSC (hBM-MSC) proliferation and its underlying molecular mechanisms. hBM-MSCs were treated with PAME for 48 h and then subjected to various analyses. The results from the present study show that PAME significantly reduced the levels of G2/M phase regulatory proteins, cyclin-dependent kinase 1 (Cdk1), and cyclin B1 and inhibited proliferation in hBM-MSCs. …”
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19194
Prenatal light exposure affects diurnal rhythms and visual development of the layer embryonic retina
Published 2025-01-01“…Layer eggs (Jingfen No.6) were subjected to white light (5000K, WL) and green light (520 nm/515-525 nm, GL) with a 12L:12D photoperiod throughout the entire incubation period, in contrast to no light incubation (NL). …”
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19195
Guidance for the gastrointestinal evaluation and management of iron deficiency in Sub-Saharan Africa
Published 2024-02-01“…These were reviewed in a round-table discussion and were subjected to two rounds of anonymised consensus voting by the full committee in an electronic Delphi exercise during 2022 using the online platform, Research Electronic Data Capture. …”
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19196
The impact of locus of control on somatic and psychological profiles of patients with irritable bowel syndrome engaging in aerobic exercise
Published 2025-02-01“…The internal LoC subgroup had a higher percentage of physically active subjects and a better physical capacity at baseline than those with external LoC. …”
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19197
Compaction of Hyaloclastite from the Active Geothermal System at Krafla Volcano, Iceland
Published 2020-01-01“…We constrained the evolution of yield curves of the hyaloclastites, subjected to different effective mean stresses in a triaxial press. …”
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19198
Seasonal distribution and cercarial shedding of Bulinus spp. snails: Implications for urogenital schistosomiasis control in the Simiyu Region, northwestern Tanzania
Published 2025-01-01“…The collected snails were morphologically identified and subjected to a cercarial emergence experiment. Water physicochemical characteristics were recorded simultaneously with snail collection using a portable multiparameter water meter. …”
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19199
The efficacy and safety of qiwei baizhu san in the treatment of type 2 diabetes mellitus: a systematic review and meta-analysis
Published 2025-01-01“…Heterogeneity sources were examined via subgroup analyses, the robustness of the results was determined by sensitivity analyses, publication bias was evaluated using funnel plots and Egger’s test, evidence quality was appraised with GRADEpro, and possible mechanisms of QWBZS for T2DM were categorized and summarized.ResultsThis analysis encompassed 14 qualifying trials with a total of 1,169 subjects. The analytical results suggested that QWBZS, when combined with conventional treatment, was more effective than conventional treatment alone in improving FBG, 2hPG, HbA1c, HOMA-IR, TC, TG, LDL-C, and HDL-C. …”
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19200
Clinical expression of facioscapulohumeral muscular dystrophy in carriers of 1–3 D4Z4 reduced alleles: experience of the FSHD Italian National Registry
Published 2016-01-01“…Relatives carrying 1–3 DRA showed a large clinical variability ranging from healthy subjects, to patients with severe motor impairment.Conclusions The size of the D4Z4 allele is not always predictive of severe clinical outcome. …”
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