Association between triglyceride-glucose index and endometriosis: results from a cross-sectional study and Mendelian randomization study by Ting Xu, Yuan Zhuang, Huabin Cao, Jingqi Yang

“…In the cross-sectional study, subjects in the highest quartile of TyG index had the highest risk of incident endometriosis after adjusting for covariates(OR = 2.41, 95% CI:1.31-4.44, P for trend <0.01). …”
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Pathogenicity of germline VHL variants is associated with renal cell carcinoma size in von Hippel-Lindau disease by Gustavo H. Mori, Gustavo F. C. Fagundes, Lucas S. Santana, Felipe Freitas-Castro, Ana Caroline F. Afonso, Delmar M. Lourenço Jr., Maria Adelaide A. Pereira, Fabio Y. Tanno, Victor Srougi, Jose L. Chambo, Mauricio D. Cordeiro, William C. Nahas, Ana O. Hoff, Maria Candida B. V. Fragoso, Berenice B. Mendonca, Ana Claudia Latronico, Madson Q. Almeida

“…ABSTRACT Objective: In this study, our aim was to search for new genotype-phenotype correlations in patients with Von Hippel-Lindau (VHL) disease. Subjects and methods: We retrospectively studied 53 consecutive patients with VHL disease and confirmed genetic diagnoses from 32 relatives. …”
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Dietary Calcium Intake and Calcium Supplementation in Hungarian Patients with Osteoporosis by Gábor Speer, Pál Szamosujvári, Péter Dombai, Katalin Csóré, Kinga Mikófalvi, Tímea Steindl, Ildikó Streicher, Júlia Tarsoly, Gergely Zajzon, Péter Somogyi, Pál Szamosújvári, Péter Lakatos

“…It was lower than recommended in 47.8% of the cases and substantially higher in 17.7% of subjects. Conclusions. We conclude that calcium intake in Hungarian osteoporotic patients is much lower than the current recommendation, while routinely applied calcium supplementation will result in inappropriately high calcium intake in numerous patients.…”
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Cost-effectiveness of metacognitive therapy for cardiac rehabilitation participants with symptoms of anxiety and/or depression: analysis of a randomised controlled trial by David Reeves, Calvin Heal, Patrick Joseph Doherty, Gemma E Shields, Adrian Wells, Lora Capobianco, Anthony Heagerty, Deborah Buck, Linda M Davies, Elizabeth Camacho

“…At a threshold of £30 000 per QALY, MCT intervention of around 76% was likely to be cost-effective.Conclusions Results suggest that intervention may be cost-saving and health-increasing; however, findings are uncertain and subject to limitations. Further research should aim to reduce the uncertainty in the findings (eg, with larger sample sizes) and explore potential longer-term economic benefits associated with MCT in this setting.…”
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Air pollution exposures in early life and brain development in children (ABC): protocol for a pregnancy cohort study by John Kinuthia, R Scott McClelland, Barbra A Richardson, Elizabeth Maleche-Obimbo, Brent R Collett, Sarah Benki-Nugent, Faridah H Were, Anne M Riederer, Michael Gatari, CJ Karr, Edmund YW Seto, Beatrice C Mutai, Susan Wamithi, Priscilla Wanini Edemba, Timothy V Larson, Julian D Marshall

“…Additional exposure assessment in a subset of the cohort includes residential indoor and outdoor air monitoring for fine particulate matter (PM2.5), carbon monoxide (CO), ultrafine particles (UFP) and black carbon (BC).Ethics and dissemination This study was approved by the Kenyatta National Hospital - University of Nairobi Ethics and Research Committee, and the University of Washington Human Subjects Division. Results are shared at annual workshops.…”
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Making stereopsis related to the ability of ocular deviation: a new paradigm for assessment of intermittent exotropia by Jian-Bing Li, Wan-Ting Kong, Tao Shen, Yong-Guang Yuan, Chong-Lin Chen, Dan-Min Peng, Min-Tong Liang, Xuan He, Dan Luo, Jia-Yi Su, Wei Wang, Rui-Xin Wang, Xin-Ping Yu

“…These scores were significantly better than those observed under natural viewing conditions, which were 2.5 (1-5) at a distance and 1 (0-3) at near (Friedman test, P=0.049). Furthermore, those subjects who exhibited exophoria (realignment within 2 seconds) while viewing 3D optotypes with polarized glasses were more likely to have measurable stereo vision (Kendall's τb=-0.344, P=0.018). …”
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The spectrum-efficacy correlation of Kai-Xin-San for cognition of Aβ42 transgenic Drosophila and verification of its active ingredients by Jinfu Wu, Hang Sun, Yiyang Zhao, Lian Lian, Hongsheng Bian, Yong Guo, Dan Li, Lili Huang

“…Finally, the spectrum-effect relationship between the KXS fingerprint and memory improvement was analyzed, with the active ingredients subjected to validation testing.ResultsThe results identified seventeen common peaks in the fingerprint, and eight active components were determined: polygalaxanthone III, 3-6-disinapoylsucrose, ginsenoside Rg1, ginsenoside Rb1, β-asarone, α-asarone, dehydrotumulosic acid, and dehydropachymic acid. …”
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Unlocking the Potential of RNA Sequencing in COVID-19: Toward Accurate Diagnosis and Personalized Medicine by Heba M. Saad Eldien, Abdulrahman H. Almaeen, Ahmed Abo El Fath, Ahmed E. Taha, Rehab Ahmed, Hassabelrasoul Elfadil, Helal F. Hetta

“…A comprehensive literature review was conducted using PubMed, Scopus, Web of Science, and Google Scholar. We employed Medical Subject Headings (MeSH) terms and relevant keywords to identify studies that explored the role of RNAseq in COVID-19 diagnostics, prognostics, and therapeutics. …”
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Gross and applied anatomy pedagogical approaches in occupational therapy education: protocol for a scoping review by Emily S Ho, Anne Agur, Andrea Duncan, Erica Dove, Kelly Hennessy, Athena Kirou-Mauro, Lorna Aitkens

“…After title/abstract and full-text screening, included articles will be charted, collated and summarised.Ethics and dissemination This study will not involve human or animal subjects. Therefore, research ethics approval is not required. …”
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High-Fiber Extruded Purple Sweet Potato ( Ipomoea batatas ) and Kidney Bean ( Phaseolus vulgaris ) Extends the Feeling of Fullness by Eny Palupi, Naufal Muharam Nurdin, Ghina Mufida, Fadhilah Nur Valentine, Ricter Pangestika, Rimbawan Rimbawan, Ahmad Sulaeman, Dodik Briawan, Fitry Filianty

“…The satiety index determination involved 16 subjects with body mass index in optimal range, and data from the visual analogue scale (VAS) questionnaire were used at 0, 30, 60, 90, 120, 150, and 180 min after consumption of the test food. …”
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Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II) by Jaeseong Jo, Chung Mo Nam, Jae Woong Sull, Ji Eun Yun, Sang Yeun Kim, Sun Ju Lee, Yoon Nam Kim, Eun Jung Park, Heejin Kimm, Sun Ha Jee

“…Furthermore, the risk of CRC significantly increased for individuals with a family history of CRC in the highest quartile of GRS when compared to subjects without a family history of CRC in the lowest quartile of GRS (counted GRS odds ratio [OR], 47.9; 95% confidence interval [CI], 4.9 to 471.8 for men; OR, 22.3; 95% CI, 1.4 to 344.2 for women) (weighted GRS OR, 35.9; 95% CI, 5.9 to 218.2 for men; OR, 18.1, 95% CI, 3.7 to 88.1 for women). …”
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Basal-Supported Oral Therapy with Sitagliptin Counteracts Rebound Hyperglycemia Caused by GLP-1 Tachyphylaxis by Shu Meguro, Toshihide Kawai, Tomohiro Matsuhashi, Motoaki Sano, Keiichi Fukuda, Hiroshi Itoh, Yoshihiko Suzuki

“…Materials and Methods. The subjects were 12 men and 3 women aged 59.9±10.0 years who had been treated with GLP-1 analogs. …”
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A Transcriptomic Analysis Reveals Diverse Regulatory Networks That Respond to Cold Stress in Strawberry (Fragaria×ananassa) by Yong Zhang, Yunting Zhang, Yuanxiu Lin, Ya Luo, Xiaorong Wang, Qing Chen, Bo Sun, Yan Wang, Mengyao Li, Haoru Tang

“…Strawberry is often subjected to cold stress in temperate regions when insulation measures are not strictly applied in protected cultivation. …”
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Dexamethasone Prophylaxis in Pediatric Open Heart Surgery Is Associated with Increased Blood Long Pentraxin PTX3: Potential Clinical Implications by Franco Lerzo, Giuseppe Peri, Andrea Doni, Paola Bocca, Fabio Morandi, Angela Pistorio, Anna Maria Carleo, Alberto Mantovani, Vito Pistoia, Ignazia Prigione

“…PTX3 levels significantly increased during CPB in dexamethasone-treated (+D) and dexamethasone-untreated (−D) subjects, but were significantly higher in +D than −D patients. …”
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TRIM26 exacerbates pathological cardiac hypertrophy by activating TAK1 by Xiaochuang Xia, Huajing Shan, Zhaoxia Jin, Tengfei Ma, Yemao Liu, Jianqing Zhang, Han Tian, Bizhen Dong, Chengsheng Xu, Shaoze Chen

“…We observed increased expression of TRIM26 in the myocardium of C57BL/6 mice subjected to transverse aortic constriction (TAC) surgery and neonatal rat cardiomyocytes (NRCMs) treated with phenylephrine (PE). …”
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Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China by Renliang Huang, Zhe Lu, Xinze Li, Duo Zhou, Jing Xu, Dan Lin, Yunxue Fu, Yan Liang, Xuexia Li, Frank Petersen, Qiaomiao Zhou, Xinhua Yu

“…Subsequently, a retrospective cohort comprising 86 cases with chronic hepatitis B virus infection and 129 control subjects recruited from the Hainan Women and Children’s Medical Center from November 2021 and January 2023 was examined. …”
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Effectiveness of nurse-led volunteer support and technology-driven pain assessment in improving the outcomes of hospitalised older adults: protocol for a cluster randomised control... by Max K Bulsara, Christopher Etherton-Beer, Rosemary Saunders, Kate Crookes, Mustafa Atee, Caroline Bulsara, Beverley Ewens, Olivia Gallagher, Renee M Graham, Karen Gullick, Sue Haydon, Kim-Huong Nguyen, Bev O'Connell, Karla Seaman, Jeff Hughes, Seng Giap Marcus Ang, Debra Scaini

“…Two interventions that have the potential to prevent progression of frailty and improve patient outcomes in hospitalised older adults but have yet to be subject to clinical trials are nurse-led volunteer support and technology-driven assessment of pain.Methods and analysis This single-centre, prospective, non-blinded, cluster randomised controlled trial will compare the efficacy of nurse-led volunteer support, technology-driven pain assessment and the combination of the two interventions to usual care for hospitalised older adults. …”
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How integrated knowledge translation worked to reduce federal policy barriers to the implementation of medication abortion in Canada: a realist evaluation by Sarah Munro, Kate Wahl, Sheila Dunn, Courtney Devane, Linda C. Li, Wendy V. Norman

“…The findings may be of relevance to researchers focused on public health topics subject to stigma.…”
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Effect of Acupuncture on Neuroplasticity of Stroke Patients with Motor Dysfunction: A Meta-Analysis of fMRI Studies by Qiuyi Lv, Guixing Xu, Yuxin Pan, Tongtong Liu, Xiaodong Liu, Linqing Miao, Xing Chen, Lan Jiang, Jie Chen, Yingjia He, Rong Zhang, Yihuai Zou

“…R software was used to analyze the continuous variables, and Seed-based d Mapping with Permutation of Subject Images (SDM-PSI) was used to perform an analysis of fMRI data. …”
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Use of virtual reality to remotely train healthcare professionals in paediatric emergency tracheostomy skills: protocol for a multi-centre, non-inferiority educational intervention... by Jonathan R. Abbas, Noorulanne Younis, Emily Johnstone, Azita Rajai, Rachel Isba, Antony Payton, Brendan A. McGrath, Neil Tolley, Iain A. Bruce

“…The primary outcome measure is skill performance in simulation in a pre- and post-intervention structure within subjects. Participant performance will also be assessed using non-inferiority metrics against historical traditional educational control data. …”
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