Effects of early neonatal proinflammatory stress on the expression of BDNF transcripts in the brain regions of prepubertal male rats by D. I. Peregud, S. V. Freiman, A. O. Tishkina, L. S. Sokhranyaeva, N. A. Lazareva, M. V. Onufriev, M. Y. Stepanichev, N. V. Gulyaeva

“…We suggest that specific alterations in BDNF expression may be involved in the susceptibility to the development of behavioral impairments of animals subjected to early proinflammatory stress.…”
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Design of Conformal Cooling of an Additively Printed Aluminium Die-Casting Mold Component by J. Sviželová, L. Socha, A. Mohamed, M. Pinta, K. Koza, T. Sellner, K. Gryc, M. Dvořák, M. Roh

“…The paper describes the design of conformal cooling of an aluminium die-casting mold component using numerical simulations along with validation under industrial conditions. The subject of modifications was the insert. The insert comes into direct contact with the metal during the filling of the mold and solidification of the casting and determines the internal shape of the casting. …”
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Estimated Visceral Adipose Tissue, but Not Body Mass Index, Is Associated with Reductions in Glomerular Filtration Rate Based on Cystatin C in the Early Stages of Chronic Kidney Di... by Ana Karina Teixeira da Cunha França, Alcione Miranda dos Santos, João Victor Salgado, Elane Viana Hortegal, Antônio Augusto Moura da Silva, Natalino Salgado Filho

“…According to BMI, 28.2% of subjects were obese. Prevalence of increased WC and eVAT was 63.9% and 58.5%, respectively. …”
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Pixel-Level Non-Local Method-Based Depth Image Inpainting by Xiaoya Dai, Yingkun Hou, Shuqi Zhang, Hao Hou, Bin Feng, Tao Lin, Mengyu Liu

“…Experimental results show that the proposed method can achieve higher PSNR values than existing methods on public datasets, and the subjective visual quality of the inpainted images is also satisfactory.…”
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Determinants of Brachial-Ankle Pulse Wave Velocity in Chinese Patients with Rheumatoid Arthritis by Ping Li, Cheng-xun Han, Cui-li Ma, Jia-long Guo, Bo Liu, Juan Du, Li-qi Bi

“…Methods. 138 Chinese RA patients and 150 healthy subjects were included. baPWV of all the participants was measured. …”
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The diagnostic and prognostic value of serum miR-199a-5p combined with echocardiography in acute myocardial infarction by Lixin Xu, Jianfeng Lin, Jianke Xia, Deng Chen, Guohan He

“…Objective The clinical significance of serum miR-199a-5p combined with echocardiography in AMI was investigated to provide some reference for clinical treatment. Methods The study subjects were 90 AMI patients and 50 acute chest pain patients (control). …”
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Protocol for the development of a global core outcome set for the surgical treatment of differentiated thyroid cancer: a literature review and international Delphi survey by Anton F Engelsman, Romana T Netea-Maier, Christiaan F Mooij, Robin P Peeters, Menno R Vriens, A S Paul van Trotsenburg, Schelto Kruijff, Joep P M Derikx, Faridi S Jamaludin, Daniël J van de Berg, Hanneke M van Santen, Sarah C Clement, Eveline Bruinstroop, Frederik A Verburg, Angelique Seur, Els J M Nieveen van Dijkum

“…The final COS will be reported in accordance with the COS-Standards for Reporting statement.Ethics and dissemination The medical research ethics committee of the Amsterdam UMC confirmed that the Dutch Medical Research Involving Human Subjects Act (WMO) does not apply to this study and that full approval by the committee is not required. …”
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Influence of the A3669G Glucocorticoid Receptor Gene Polymorphism on the Metabolic Profile of Pediatric Patients with Congenital Adrenal Hyperplasia by Ricardo P. P. Moreira, Larissa G. Gomes, Guiomar Madureira, Berenice B. Mendonca, Tânia A. S. S. Bachega

“…A3669G carriers presented higher LDL-c levels compared to wild-type subjects. BclI-carriers and noncarriers did not differ. …”
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Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…Then, we found that histone H3 acetylation levels were significantly lower in GD and HD patients than in control subjects and these differences were larger than the daily variation in histone acetylation. …”
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General practitioners’ clinical decision-making in patients that could have cancer: a vignette study comparing the Baltic states with four Nordic countries by Alexander Rosendahl, Anet Vanaveski, Liina Pilv-Toom, Jānis Blumfelds, Vija Siliņa, Mette Brekke, Tuomas Koskela, Aurimas Rapalavičius, Hans Thulesius, Peter Vedsted, Michael Harris

“…This study investigated the likelihood of General Practitioners (GPs) investigating or referring patients with a low but significant risk of cancer in these two regions, and how this was affected by GP demographics.Design A survey of GPs using clinical vignettes.Setting General Practice in Denmark, Estonia, Finland, Latvia, Lithuania, Norway, and Sweden.Subjects General Practitioners.Outcome measures A regional comparison of GPs’ stated immediate diagnostic actions (whether or not they would perform a key diagnostic test and/or refer to a specialist) for patients with a low but significant risk of cancer (between 1.2 and 3.6%).Results Of the 427 GPs that completed the questionnaire, those in the Baltic states, and GPs that were more experienced, were more likely to arrange a key diagnostic test and/or refer their patient to a specialist than those in Nordic Countries or who were less experienced (p < 0.001 for both measures). …”
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Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations by Guillem López de Egea, Aida González-Díaz, Randall J Olsen, Gérard Guédon, Dàmaris Berbel, Immaculada Grau, Jordi Càmara, Lucía Saiz-Escobedo, Sara Calvo-Silveria, Irene Cadenas-Jiménez, José María Marimón, Emilia Cercenado, Antonio Casabella, Sara Martí, M. Ángeles Domínguez, Nathalie Leblond-Bourget, James M Musser, Carmen Ardanuy

“…Isolates were tested for antimicrobial susceptibility (European Committee on Antimicrobial Susceptibility Testing 2023), subjected to whole genome sequencing and analyzed for mobile genetic elements (MGEs). …”
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High-flow nasal cannula oxygen therapy versus non-invasive ventilation in healthy respiratory physicians: a non-randomized study by Hong Ye, Dandan Xiang, Xiangyu Zhu, Xiuwei Du, Shengyun Shang, Jing Xu, Yu Li, Yunyun Cheng, Zhongfei Yang

“…This study aims to first establish whether to use HFNC or NIV based on comfort levels, and subsequently evaluate diaphragmatic function under equivalent comfort levels to determine the optimal modality for clinical application.MethodsA self-controlled, non-randomized study was conducted with 10 healthy respiratory physicians as participants. Each subject was exposed to different HFNC settings, including flow rates of 20, 40, and 60 L/min at both 33 and 37°C. …”
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Nucleotide Sequencing and Identification of Some Wild Mushrooms by Sudip Kumar Das, Aninda Mandal, Animesh K. Datta, Sudha Gupta, Rita Paul, Aditi Saha, Sonali Sengupta, Priyanka Kumari Dubey

“…The rDNA-ITS (Ribosomal DNA Internal Transcribed Spacers) fragment of the genomic DNA of 8 wild edible mushrooms (collected from Eastern Chota Nagpur Plateau of West Bengal, India) was amplified using ITS1 (Internal Transcribed Spacers 1) and ITS2 primers and subjected to nucleotide sequence determination for identification of mushrooms as mentioned. …”
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Elevated Circulating hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b in Type 2 Diabetes Mellitus with Diarrhea-Predominant Irritable Bowel Syndrome by Wenhua Tao, Xiaoyun Dong, Guimei Kong, Penghua Fang, Xiaoli Huang, Ping Bo

“…Microarray technology and real-time reverse transcriptase-polymerase chain reaction analysis (RT-PCR) were taken to examine the miRNA expression profiles of T2DM patients with diarrhea-predominant irritable bowel syndrome (D-IBS) compared with patients with T2DM, patients with D-IBS, and control subjects. Results. We have found that 35 miRNAs were differentially expressed in T2DM with D-IBS, in which three representative miRNAs, hsa-miR-106b, hsa-miR-26a, and hsa-miR-29b, were found to be significantly elevated in T2DM with D-IBS by RT-PCR. …”
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The Role of Interpersonal Relationships in Adolescents' Suicidal Behavior: A Qualitative Analysis of Semi-Structured Interviews by N.A. Polskaya, D.K. Yakubovskaya, D.A. Sharova, A.Ya. Basova

“…Within the framework of the thematic analysis, two superordinate themes and nine subthemes were identified, revealing the subjective experience of the suicide attempt. The first superordinate theme, <em>psychological distress</em>, includes the subthemes of &ldquo;negative thoughts and emotions&rdquo;, &ldquo;mental pain&rdquo; and &ldquo;fear of surviving&rdquo;. …”
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Action Imagery and Observation in Neurorehabilitation for Parkinson’s Disease (ACTION-PD): Development of a User-Informed Home Training Intervention to Improve Functional Hand Move... by Judith Bek, Paul S. Holmes, Chesney E. Craig, Zoë C. Franklin, Matthew Sullivan, Jordan Webb, Trevor J. Crawford, Stefan Vogt, Emma Gowen, Ellen Poliakoff

“…Exploratory outcomes also suggested that subjective and objective performance of manual actions should be tested in a larger trial. …”
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Multiple-Wearable-Sensor-Based Gait Classification and Analysis in Patients with Neurological Disorders by Wei-Chun Hsu, Tommy Sugiarto, Yi-Jia Lin, Fu-Chi Yang, Zheng-Yi Lin, Chi-Tien Sun, Chun-Lung Hsu, Kuan-Nien Chou

“…Seven inertial measurement unit (IMU) sensors were placed at seven locations: the lower back (L5) and both sides of the thigh, distal tibia (shank), and foot. The 20 subjects selected to participate in this study were separated into two groups: stroke patients (11) and patients with neurological disorders other than stroke (brain concussion, spinal injury, or brain hemorrhage) (9). …”
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Association between herpes simplex virus infection and Alzheimer’s disease biomarkers: analysis within the MAPT trial by Morgane Linard, Isabelle Garrigue, Bruno Vellas, Nicola Coley, Henrik Zetterberg, Kaj Blennow, Nicholas James Ashton, Pierre Payoux, Anne-Sophie Salabert, Jean-François Dartigues, Joachim Mazere, Sandrine Andrieu, Catherine Helmer

“…The trend toward lower cortical amyloid load in HSV-1-infected participants was unexpected given the pre-existing literature and may be explained either by a modified immune response in HSV-1 infected subjects which could favour the clearance of amyloid deposits or by a selection bias.…”
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Intervention effect of ventilator‑assisted emergency endoscopy in the treatment of cirrhosis‑associated esophagogastric variceal bleeding by Xiu-Lian Wu, Yanmei Gu, Wenhui Wang, Jiayuan Wei, Xiaoqing Sun, Wenyue Hu, Wenhui He

“…The patients may experience stress and anxiety before being subjected to the procedure. Aim: This study aimed to investigate the effect of ventilator-assisted emergency endoscopy in the treatment of cirrhosis-associated EGVB. …”
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Comparison of Two Creatinine-Based Equations for Predicting Decline in Renal Function in Type 2 Diabetic Patients with Nephropathy in a Korean Population by Eun Young Lee, Young-Mi Lee, Kyu Hun Choi, Hyun Chul Lee, Byung-Wan Lee, Beom Seok Kim

“…During the follow-up period (median, 2.4 years), the CKD-EPI equation reclassified 10.9% of all MDRD-estimated subjects: 9.1% to an earlier stage of CKD and 1.8% to a later stage of CKD. …”
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