Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity by Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang

“…A GSTM1 null polymorphism was identified in pharmacogenomics test and the drug concentrations was higher in GSTM1 null subjects than GSTM1 functional subjects. The apparent drug clearance was 13-fold lower in GSTM1 null subjects than GSTM1 functional subjects (p < 0.001). …”
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Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection by Miriam Lichtner, Claudia Mascia, Ilaria Sauzullo, Fabio Mengoni, Serena Vita, Raffaella Marocco, Valeria Belvisi, Gianluca Russo, Vincenzo Vullo, Claudio M. Mastroianni

“…Among TB-infected subjects, the frequencies of multifunctional CD4+ T cells, simultaneously producing all 3 cytokines, are lower in active TB than LTBI subjects P=0.003. …”
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To Determine the Role of Human Papillomavirus in Oral Cancer—A Prospective Study by Mohd Zeeshan, Asim M. Khan, Md Sibgatullah, Jayesh, Rama Brahmam Lanke, Boyapati Ramanarayana, Vikas Singh

“…Methodology: We selected an adequate number of subjects with the same parameters for both the case and the controls based on detailed case histories, specifically taking into account the adverse habits (tobacco in any form and alcohol) that each subject had recorded. …”
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The Influence of Functional Fitness and Cognitive Training of Physical Disabilities of Institutions by I-Chen Yeh, Chia-Ming Chang, Ko-Chia Chen, Wei-Chin Hong, Yu-Hsiung Lu

“…The age of the subjects was between 56 and 98 years with a mean age of 79.08 ± 10.04 years; the subjects of training group implemented 12 weeks of training on physical and cognitive training, while the control group subjects did not have any training program. …”
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Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population by Priti Sharma, Vipin Bihari, Sudhir K. Agarwal, Sudhir K. Goel

“…Exposed symptomatic group consisted of 36.8% subjects who were GSTM1 null genotyped as compared to asymptomatic where only 19.4% subjects were null. …”
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Body Mass Index’s Role in Determining Maximum Mouth Opening Using the Three-Finger Index in People of Aligarh city, Uttar Pradesh by Pradhuman Verma, Kanika Gupta Verma, Abhinaba Das, Mohammed Najmuddin, Naseebia Khan, Muzammil Moin Ahmed

“…Group I included under-weight (18.5 and less) subjects, Group II: normal (18.5 to 24.9), Group III: over-weight (25–29.9), and Group IV: subjects with obesity (≥30), based on BMI. …”
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Mild Late-Onset Sensory Neuropathy Associated with Heterozygous Missense GDAP1 Variants by Nivedita U. Jerath

“…This study presents the clinical and electrophysiological findings of four subjects with a pathogenic heterozygous GDAP1 variant causing Charcot–Marie–Tooth disease 2K (CMT2K) and one additional subject with an uncertain GDAP1 variant and clinical findings of CMT 2K. …”
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Natūrfilosofinės subjekto ir gamtos apibrėžtys: F. W. J. Schellingas ir I. H. Grantas by Domas Junelis

“… This article examines the notions of subject and nature as well as their relationship in F. …”
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Vers une conception de l’élève-sujet : la relation enseignant-élève en dispositif relais by Maël Virat

“…The concept of pupil-subject, although implicit in the teachers’discourse, highlights the recognition of the thoughts and feelings of the pupils. …”
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Sorties scolaires dans les musées de sciences : étudier l’émancipation par l’analyse du sujet didactique by Cora Cohen-Azria

“…From a didactical point of view, studying those situations leads us to analyse them through the notion of subject. Indeed, it comes to analyse together, on one hand, the didactic subject during singular situations like academic visits in museum, on an other hand, the institutional subject according to the reference institution involved in this partnership, finally the subject author of speeches (scientifical, museological or scholastic sciences). …”
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Ralph Waldo Emerson, ou le génie de l’imitation by Thomas Constantinesco

“…Emerson’s essays testify to the writing subject’s desire for originality, his will to stop “[groping] among the dry bones of the past” (Nature, 27) in order to project himself ahead, literally to ex-press himself. …”
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Du « je » au « nous ». Le Théâtre de l’opprimé comme grammaire d’une parole collective by Sophie Coudray

“…The Theatre of the Oppressed appears as a theatrical pedagogy dedicated to “non-actors” – oppressed, vulnerable subjects – whose openly activist purpose implies the construction of a collective political subject. …”
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Comparison of Effect on the Strength Training by Using Positive and Inverted Pyramid Methods by Yanna ZHU, Yupeng LIU, Guanghu YU, Junfeng GUO, Jun LONG, Shujie SU, Shunji SHEN

“…Objective:To compare the training effects of the quadriceps muscle strength of health adults under two training patterns: positive and inverted pyramid methods.Methods:Eighty health adults were divided into two groups: 40 subjects had strength training experience and the other 40 subjects did not have strength training experience. …”
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Subiekt semantyczny w zdaniach typu „Ему хочется спать” w porównaniu z językiem polskim by Anna Rudyk

“…The dative case is the only explicit way to indicate the semantic subject. This kind of subject can also be ascertained from the context or remain undetermined if information about its referent is missing.…”
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Pulse Wave Velocity as Marker of Preclinical Arterial Disease: Reference Levels in a Uruguayan Population Considering Wave Detection Algorithms, Path Lengths, Aging, and Blood Pres... by Ignacio Farro, Daniel Bia, Yanina Zócalo, Juan Torrado, Federico Farro, Lucía Florio, Alicia Olascoaga, Walter Alallón, Ricardo Lluberas, Ricardo L. Armentano

“…A conservative approach was used, and we excluded symptomatic subjects; subjects with history of cardiovascular (CV) disease, diabetes mellitus or renal failure; subjects with traditional CV risk factors (other than age and gender); asymptomatic subjects with atherosclerotic plaques in carotid arteries; patients taking anti-hypertensives or lipid-lowering medications. …”
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Efficacy of Shenqi Pollen Capsules for High-Altitude Deacclimatization Syndrome via Suppression of the Reoxygenation Injury and Inflammatory Response by Binfeng He, Mingdong Hu, Zhihui Liang, Qianli Ma, Yunhai Zi, Zhiwei Dong, Qi Li, Yongjun Luo, Guisheng Qian, Liang Guo, Kexiong Lin, Zhenyu Liu, Guansong Wang

“…All subjects were at the same high altitude (3650 m) for 4-8 months before returning to lower altitudes. …”
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Crossmodal Recruitment of the Ventral Visual Stream in Congenital Blindness by Maurice Ptito, Isabelle Matteau, Arthur Zhi Wang, Olaf B. Paulson, Hartwig R. Siebner, Ron Kupers

“…We used functional MRI (fMRI) to test the hypothesis that blind subjects recruit the ventral visual stream during nonhaptic tactile-form recognition. …”
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Abnormal Blood Glucose as a Prognostic Factor for Adverse Clinical Outcome in Children Admitted to the Paediatric Emergency Unit at Komfo Anokye Teaching Hospital, Kumasi, Ghana by Emmanuel Ameyaw, Kwame Amponsah-Achiano, Peter Yamoah, Jean-Pierre Chanoine

“…Forty subjects died out of whom 30 had dysglycaemia (P=0.001). …”
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Influences of occupational therapy as curricular activity on to psychophysical development of hearing-impaired students by Oana Rusu, Demmy Rusu

“…Two instruments (test-retest at an 18month interval) have been used for the hearingimpaired pupils of the &ldquo;VasilePavelcu&rdquo; Technological Special High School in Iasi: the scale of multidimensional attitudes for self-esteem E.T.E.S. (N=45 subjects, 24 boys and 21 girls, aged between 13 and 18) in elementary and high school, each groups of 15 subjects; the test Ozeretski &ndash; Guillmain (N= 45 de subjects: 25 boys and 20 girls, aged between 8 and 12) in primary and elementary school. …”
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Detection of mental disorders with the Patient Health Questionnaire in primary care settings in Nigeria by Michael O. Olatawura, Olawale Olusegun Ogunsemi, Christopher O. Alebiosu, Olufemi E. Amoran, Adekunle J. Ariba, Francis A. Oluwole, Festus Abasiubong, Adebayo R. Erinfolami

“…The PHC physicians were only able to diagnose disorders relating to mental health in 52 (12.6%) of the subjects. Health and work situations accounted for more than three-quarters of the causes of stress experienced by the subjects. …”
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