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1961
Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort
Published 2024-12-01“…Objectives To describe the population that meets the criteria for major depressive disorder (MDD) in British Columbia (BC), compare patterns of healthcare utilisation between those with MDD who are and are not prescribed pharmacotherapy, and assess these relationships in models that control for potential confounding variables.Design We used a population cross-sectional study design among a cohort of individuals living with MDD and examined the relationship between pharmacotherapy and healthcare utilisation between 2019 and 2020 using linked billing and administrative data.Setting This study identified individuals with MDD using a validated case definition of International Classification of Diseases (ICD) codes in BC, Canada.Participants The final study cohort included 549 029 adult participants who met the MDD case definition.Explanatory variable Explanatory variable was the use of prescription antidepressant medication during the study period, based on BC PharmaNet data.Covariates Covariates include sociodemographic characteristics (age, sex, urban/rural residence, neighbourhood income quintile and comorbidities).Primary outcome measure Primary outcome measure was healthcare utilisation (outpatient physician visits, emergency department (ED) visits and hospitalisations).Results We stratified our analysis based on whether study participants were classified as ‘recently incident’ or ‘actively prevalent’. …”
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Article -
1962
What are the barriers to the diagnosis and management of chronic respiratory disease in sub-Saharan Africa? A qualitative study with healthcare workers, national and regional polic...
Published 2022-07-01“…This study aimed to explore the perspectives of healthcare workers and other health policy stakeholders on the barriers to effective diagnosis and management of CRD in Kenya, Malawi, Sudan, Tanzania and Uganda.Study design Qualitative descriptive study.Settings Primary, secondary and tertiary health facilities, government agencies and civil society organisations in five sub-Saharan African countries.Participants We purposively selected 60 national and district-level policy stakeholders, and 49 healthcare workers, based on their roles in policy decision-making or health provision, and conducted key informant interviews and in-depth interviews, respectively, between 2018 and 2019. …”
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Article -
1963
Body image and attitudes toward cosmetic surgeries among female college students in the United Arab Emirates: A cross-sectional study
Published 2025-01-01“…Methods: This study utilized a cross-sectional study design. Data were collected using Demographic Data Questionnaires, Cosmetic-related Questionnaire, the Body Appreciation Scale (BAS), and the Attitude Toward Cosmetic Surgery Scale (ACSS). …”
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Article -
1964
Hubungan Kecanduan Bermain Video Games Kekerasan dengan Perilaku Agresif pada Murid Laki-laki Kelas IV dan V di SD Negeri 02 Cupak Tangah Pauh Kota Padang
Published 2015-01-01“…The objective of this study was to determine the relationship of behavioral addiction playing violent video games toward aggressive behavior in boys elementary school grade IV and V in State Elementary School 02 Cupak Tangah Pauh Padang.This study used a cross sectional study design with total sample of 83 students grade IV and V. …”
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Article -
1965
Study protocol for key interventions to improve the follow-up adherence postcervical precancerous lesion treatment in Ethiopia: a pragmatic randomised controlled trial
Published 2025-01-01“…Thus, the objective of this study is to evaluate key interventions to improve the follow-up adherence rate among women treated for suspicious cervical lesions in primary healthcare settings in Ethiopia.Method and analysis We will employ a pragmatic randomised control trial study design, using Consolidated Standards of Reporting Trials guidelines for reporting and a Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist for developing the protocol, to evaluate intervention effectiveness. …”
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Article -
1966
Impact of prior SARS-CoV-2 infection and COVID-19 vaccination on the subsequent incidence of COVID-19: a multicentre prospective cohort study among UK healthcare workers – the SIRE...
Published 2022-06-01“…This study aims to determine whether prior SARS-CoV-2 infection or COVID-19 vaccination in healthcare workers protects against future infection.Methods and analysis This is a prospective cohort study design in staff members working in hospitals in the UK. …”
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Article -
1967
A phase Ia study of a novel anti-HER2 antibody–drug conjugate GQ1001 in patients with previously treated HER2 positive advanced solid tumors
Published 2025-01-01“…Methods In this phase Ia trial, a modified 3 + 3 study design was adopted during dose escalation phase. …”
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Article -
1968
Female Adolescent Soccer Players Utilize Different Neuromuscular Strategies Between Limbs During the Propulsion Phase of a Lateral Vertical Jump
Published 2021-06-01“… # Purpose To examine dominant versus non-dominant limb performance using energy generation contribution of the hip, knee, and ankle during the vertical jump component of the lateral vertical jump. # Study Design Cross-sectional observational study. # Methods Seventeen healthy, adolescent female soccer players (age 13.4±1.7 years; height 160.6±6.0 cm; mass 53.1±8.2 kg) participated. …”
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Article -
1969
Supplementation of Nodulisporium sp. KT29 induced by Vibrio harveyi as an immunostimulant for controlling vibriosis in vannamei white shrimp under marine culture system
Published 2020-09-01“…KT29 supplementation with various Vibrio harveyi induction in feed against vibriosis in vannamei white shrimp. The study design included KP (positive control without supplementation Nodulisporium sp. …”
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Article -
1970
Impact of ambient temperatures on Alzheimer's disease and other dementia mortality among elderly patients aged 60 years and older in China
Published 2024-12-01“…Using an individual-level time-stratified case-crossover study design, the relationships between ambient temperatures and AD and other dementia mortality were quantified using conditional logistic regression combined with the distributed lag nonlinear model. …”
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Article -
1971
Automatic deep learning-based colorectal adenoma detection system and its similarities with pathologists
Published 2020-09-01“…The simple criteria of colorectal adenoma diagnosis make it to be a perfect testbed for this study.Design The deep learning model was trained by 177 accurately labelled training slides (156 with adenoma). …”
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Article -
1972
Influence of Organ‐Specific Extranodal Involvement on Survival Outcomes in Stage IV Diffuse Large B‐Cell Lymphoma
Published 2025-01-01“…Additionally, we assessed the effect of ASCT on 5‐year progression‐free survival (PFS) and overall survival (OS) in patients with different extranodal sites involved. Study Design A retrospective bicenter study. Results Univariate analysis revealed a significant decrease in survival rates in patients with a Deauville score of 3 and those with extranodal DLBCL affecting the spleen, bone marrow, nasosinus, and liver. …”
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Article -
1973
Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth.
Published 2020-01-01“…We further constructed a network of these gene signatures and identified the common biological pathways involved.<h4>Study design</h4>We conducted peripheral blood transcriptome profiling at 10-18 weeks of gestation in a nested case-control cohort of 24 pregnant women who participated in the Vitamin D Antenatal Asthma Reduction Trial (VDAART). …”
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Article -
1974
Evaluation of a peer support group programme for vulnerable host population and refugees living with diabetes and/or hypertension in Lebanon: a before-after study
Published 2025-01-01“…We used a before-after study design and included a control group for clinical outcomes. …”
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Article -
1975
Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis
Published 2025-03-01“…We evaluated and compared risk of incident stroke and dementia between old and new equations of eGFR for African American and non-African American participants. Study Design: Prospective observational study. Setting & Participants: Baseline values were collected from 6,814 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort between 2000 and 2002. …”
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Article -
1976
Prenatal vitamin utilization and its determinants among pregnant women in south Gondar zone: multicenter cross-sectional study
Published 2025-01-01“…This study aimed to assess utilization and associated factors of prenatal vitamins among pregnant women attending antenatal care at public hospitals in the south Gondar zone, 2024MethodsMulti center crossectional study design was conducted among 416 pregnant women from March 1 to May 30, 2024. …”
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Article -
1977
Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Pr...
Published 2025-01-01“…Limitations include the retrospective and single-center study design. Conclusions and clinical implications: Prostate volume ≥150 ml is associated with a longer operative time, a higher rate of major complications, and a more frequent need for blood transfusion. …”
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Article -
1978
Incident Heart Failure in Atherosclerotic Renal Artery Stenosis: A Post Hoc Analysis of the CORAL Trial
Published 2025-02-01“…Rationale & Objective: Although renal artery stenosis (RAS) and heart failure (HF) have been linked, the incidence and predictors of HF among patients with RAS are not well described. Study Design: Post hoc analysis of the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) multicenter, open-label, randomized controlled trial (RCT). …”
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Article -
1979
Efficacy and safety of Jianpi Qinghua granules for non-erosive reflux disease with spleen deficiency and damp-heat syndrome: a multicenter, randomized, double-blind, placebo-contro...
Published 2025-01-01“…Jianpi Qinghua (JQ) granules, a traditional Chinese medicine, have shown promise in treating NERD by targeting symptoms of spleen deficiency and damp-heat syndrome.PurposeThis study aims to evaluate the efficacy and safety of JQ granules in treating patients with NERD characterized by spleen deficiency and damp-heat syndrome.Study designA multicenter, randomized, double-blind, placebo-controlled clinical trial was conducted with a total of 78 NERD patients randomly assigned to receive either JQ granules or placebo for 4 weeks, followed by a 4-week follow-up period.MethodsSeventy-eight NERD patients with spleen deficiency and damp-heat syndrome were recruited and randomly assigned to receive either JQ granules (n = 39) or placebo (n = 39). …”
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Article -
1980
