Pathway to care among adolescents and young adults with breast cancer in Nigeria: a mixed methods study by Atara Ntekim, Ayorinde Folasire, Oluwaponmile A. Odukoya, Anthonia Sowunmi, Adewunmi Alabi

“…Methods A mixed-method convergent parallel study design was used. The study was conducted at two academic hospitals in southwest Nigeria. …”
Get full text

Incidence of cancer-related lymphoedema: a protocol for a living systematic review with meta-analysis by Nele Devoogdt, Hildegard Reul-Hirche, Kira Bloomquist, Michael Bernas, Ben Singh, Sandi Hayes, Melanie Plinsinga, Debbie Geyer, Louise Koelmeyer, Neil Piller, Stanley Rockson

“…Two investigators will independently extract data and assess the risk of bias using the Cochrane Risk of Bias Tool Version 2.0, the Risk of Bias in Non-randomised Studies – of Interventions or the National Institutes of Health Heart, Lung and Blood Institute Study Quality Assessment Tools, depending on study design. The overall strength of evidence will be appraised with the Grading of Recommendations, Assessment, Development and Evaluations tool. …”
Get full text

Severe Obesity in Women Can Lead to Worse Memory Function and Iron Dyshomeostasis Compared to Lower Grade Obesity by Jessica M. V. Pino, Vitória F. Silva, Marcos Mônico-Neto, Danielle C. Seva, Melissa Y. Kato, July N. Alves, Gabriela C. Pereira, Hanna Karen M. Antunes, Thales D. Galvao, Lia R. A. Bitterncourt, Sergio Tufik, Lysien I. Zambrano, Ana R. Dâmaso, Lila M. Oyama, David Thivel, Raquel M. S. Campos, Kil S. Lee

“…This study aims to evaluate the cognitive function of subjects with distinct degrees of obesity, comparing class I and II obesity (OBI/II) to class III obesity (OBIII), and to investigate metabolic markers that can distinguish OBIII from OBI/II. Study Design. This is a cross-sectional study, in which 45 females with BMI varying from 32.8 to 51.9 kg/m2 completed a set of 4 cognitive tests (verbal paired-associate test, stroop color, digit span, and Toulouse–Pieron cancellation test) and their plasma metabolites, enzymes, and hormones related to glycemia, dyslipidemia, and liver function, as well as the biomarkers of iron status, were concomitantly analyzed. …”
Get full text

Effectiveness of women-led community interventions in improving tuberculosis preventive treatment in children: results from a comparative, before–after study in Ethiopia by Jacob Creswell, Degu Jerene, Ahmed Bedru, Dawit Assefa, Kalkidan Tesfaye, Samuel Bayu, Samuel Seid, Fikirte Aberra, Amera Khan

“…Objectives Our objective was to evaluate the impact of a service delivery model led by membership-based associations called Iddirs formed by women on tuberculosis preventive treatment (TPT) initiation and completion rates among children.Design Comparative, before-and-after study design.Setting Three intervention and two control districts in Ethiopia.Participants Children who had a history of close contact with adults with infectious forms of tuberculosis (TB). …”
Get full text

Bacteriological quality and predictors of raw meat collected from municipal slaughterhouse and butcher shops in northeast, Ethiopia by Leykun Berhanu, Adinew Gizeyatu, Masresha Abebe, Daniel Teshome, Mohammed Aragaw, Gete Berihun

“…To protect customers’ health from numerous foodborne diseases this study aimed to determine the microbial quality and predictors of meat along the meat value chain in Northeast, Ethiopia.ObjectiveTo determine the bacteriological quality of meat and its predictors obtained from the Dessie City Administration’s municipal slaughterhouse and butcher shops.Materials and methodsA laboratory-based cross-sectional study design was used. In total 177 meat and 354 swab samples were collected. …”
Get full text

Cohort profile: Anhui Maternal–Child Health Study in China by Yunxia Cao, Ruoling Chen, Weiju Zhou, Xiaofeng Xu, Xiaoqing Peng, Jiaqian Yin, Chunmei Liang, Ranjit Khutan, Fang-Biao Tao

“…Purpose The Anhui Maternal–Child Health Study (AMCHS) aims to examine determinants of reproduction, pregnancy and postpartum maternal and child health outcomes in Chinese women who received assisted reproductive technology (ART).Study design and participants AMCHS is an ongoing cohort study starting from May 2017. …”
Get full text

Hubungan Kadar FT4 dengan Gejala Klinis yang Terkait Efek Simpatis berdasarkan Indek Wayne pada Nagari Koto Salak Kabupaten Dharmasraya by Nining Kurniawati, Eva Decroli, Yulistini Alioes

“…This research used cross sectional study design. According to the research found that subjects with elevated levels of FT4 12.96%. …”
Get full text

Development and validation of a novel risk-predicted model for early sepsis-associated acute kidney injury in critically ill patients: a retrospective cohort study by Bo Li, Kun Zhang, Cong-Cong Zhao, Zi-Han Nan, Yan-Ling Yin, Li-Xia Liu, Zhen-Jie Hu

“…Objectives This study aimed to develop a prediction model for the detection of early sepsis-associated acute kidney injury (SA-AKI), which is defined as AKI diagnosed within 48 hours of a sepsis diagnosis.Design A retrospective study design was employed. It is not linked to a clinical trial. …”
Get full text

Comparative cross-sectional study on the prevalence, determinants and willingness to use long-acting reversible contraception among female students attending public and private uni... by Tope Michael Ipinnimo, Taofeek Adedayo Sanni, Kabir Adekunle Durowade, Olusegun Elijah Elegbede, Kayode Rasaq Adewoye, Oluseyi Adedeji Aderinwale, John Olujide Ojo, Ayo Kamal Alabi, Richard Dele Agbana, Joy Bosan

“…The aim of this study was to determine the prevalence, determinants and willingness to use LARC among undergraduate female students attending public and private universities in Ekiti State, Southwest NigeriaDesign This survey employed a cross-sectional comparative study design.Setting Public and private universities in Ekiti State, Southwest Nigeria.Participants 418 female students in their undergraduate years at public and private universities (208 students in public universities and 210 students in private universities).Primary and secondary outcomes A semistructured questionnaire was used to gather data, and analysis was done using IBM SPSS V.25. …”
Get full text

Factors influencing survival outcomes in patients with stroke at three tertiary hospitals in Zimbabwe: A 12-month longitudinal study. by Farayi Kaseke, Lovemore Gwanzura, Cuthbert Musarurwa, Elizabeth Gori, Tawanda Nyengerai, Timothy Kaseke, Aimee Stewart

“…<h4>Methods</h4>Employing a longitudinal study design, participants were observed for 12 months from baseline, censoring survivors at the endpoint. …”
Get full text

Impact of the COVID-19 pandemic on utilisation of facility-based essential maternal and child health services from March to August 2020 compared with pre-pandemic March–August 2019... by Grace J Chan, Delayehu Bekele, Bezawit Mesfin Hunegnaw, Kimiko Van Wickle, Chalachew Bekele, Fanos Ashenafi Gebremeskel, Michelle Korte, Christine Tedijanto, Lisanu Taddesse

“…We aimed to assess maternal, newborn and child health (MNCH) service utilisation during the first 6 months of the COVID-19 pandemic compared with prior to the pandemic.Methods We conducted a mixed study design in eight health facilities that are part of the Birhan field site in Amhara, Ethiopia and compared the trend of service utilisation in the first 6 months of COVID-19 with the corresponding time and data points of the preceding year.Result New family planning visits (43.2 to 28.5/month, p=0.014) and sick under 5 child visits (225.0 to 139.8/month, p=0.007) declined over the first 6 months of the pandemic compared with the same period in the preceding year. …”
Get full text

Magnitude of fruit and vegetable consumption and its associated factors among patients with type 2 diabetes mellitus (T2DM) attending health services at selected health centers in... by Lelisa Worku, Burtukan Hussien, Teshome Bekele Elema, Taferi Atomsa Rekiti, Amana Ogatu Luke, Addisu Tadesse Sime

“…Objective To assess the fruit and vegetable (FV) consumption, and associated factors among patients with type 2 diabetes mellitus (T2DM) attending health services at selected health centres.Methods Institution-based cross-sectional study design was conducted. A study was conducted in selected health centres of Yeka subcity, Addis Ababa, from 2 March 2022 to 5 May= 2022. …”
Get full text

Evaluation of the antidiabetic and antinephritic effects of Pueraria tuberosa and Pterocarpus santalinus extracts co-encapsulated in nanostructured lipid carriers in streptozotocin... by Gyamcho Tshering Bhutia, Asit Kumar De, Manas Bhowmik, Pavia Bera, Tanmoy Bera

“…The promising experimental results suggest that this formulation holds potential for further clinical exploration. Study design: The in vivo study evaluated the therapeutic potential of NLCs loaded with hydroalcoholic extracts of P. tuberosa tubers (PTE) and P. santalinus heartwood (PSE) in managing DN over eight weeks in streptozotocin (STZ)-induced diabetic mice. …”
Get full text

Narrative Review of Free Radicals and Reactive Oxygen Species in Otitis Media by Jeongmin Lee, Seok Min Hong, Yong Sung Choi, Jinseok Lee, Joon Hyung Yeo, Sung Soo Kim, Jae Min Lee, Dong Keon Yon, Seung Geun Yeo

“…Although the levels of free radicals and ROS varied by type of OM, study design, control group selection, sample type, ROS and free radical markers, and antioxidant types, most studies showed increased ROS and decreased antioxidants in OM patients. …”
Get full text

“Knowledge was clearly associated with education.” epistemic positioning in the context of informed choice: a scoping review and secondary qualitative analysis by Niamh Ireland-Blake, Fiona Cram, Kevin Dew, Sondra Bacharach, Jeanne Snelling, Peter Stone, Christina Buchanan, Sara Filoche

“…., knowledge that was tested, study design) and testimony (e.g., population descriptors) developed a priori. …”
Get full text

Prehabilitation during neoadjuvant therapy in patients with cancer of the upper gastrointestinal tract and rectum—the study protocol by Irina Chmelova, Irina Chmelova, Dalibor Pastucha, Dalibor Pastucha, Tomas Hudecek, Zdenek Guran, Zdenek Guran, Sona Ciecotkova, Lubomír Martínek, Jana Zubikova, Alena Matlova, Jakub Dolezel, Dana Salounova, Jakub Chmelo

“…This is a single group study design, with all patients enrolled receiving the intervention.MethodsThis is an interventional feasibility study of a prehabilitation programme in the form of physical training conducted at home. …”
Get full text

“If that would have lessened my symptoms, that would have been great...”: a qualitative study about the acceptability of tecovirimat as treatment for mpox by Sara Paparini, Rosalie Hayes, Benjamin Weil, Will Nutland, Ismael Maatouk, Teodora Wi, Chloe M. Orkin, Rosamund Lewis

“…Methods A co-produced, qualitative, focus group study design was conducted with a theoretically informed sample of people from communities at higher risk and with experience of mpox illness. …”
Get full text

Impacts of National Reimbursement Drug Price Negotiation on drug accessibility, utilization, and cost in China: a systematic review by Zheng Zhu, Jiawei Zhang, Zhihu Xu, Quan Wang, Yu Qi, Li Yang

“…One of the following outcomes had to be reported: drug price, availability, affordability, utilization, cost, or health outcomes. The study design had to be a randomized or non-randomized trial, an interrupted time series (ITS) analysis, a repeated measures study, or a controlled before‐after (CBA) study. …”
Get full text

Cross-sectional Study of EMG and EMG Rise During Fast and Slow Hamstring Exercises by Kasper Krommes, Markus Due Jakobsen, Thomas Bandholm, Lars Louis Andersen, Mette Zebis, Anthony Shield, Per Hölmich, Kristian Thorborg

“… # Purpose This cross-sectional study therefore aimed to compare the Nordic Hamstring curl with a conventional prone Leg Curl at different loads, and novel high velocity Hamstring Catches; in terms of peak normalized electromyographical activity (nEMG) and rate of electromyographic rise (RER) of Biceps Femoris long head, and angular velocity of the knee. # Study design Cross-sectional study. # Methods Out of 28 participants enrolled, the final sample included 23 recreationally active male participants who attended a session for determining RM (repetition maximum) to establish loading (8 and 16RM for Hamstring Catches, and 8, 16 and 24RM for Leg Curl) and to familiarize themselves with the three different exercises (Nordic Hamstring, Leg Curl and Hamstring Catch), and a testing session >4 days after during which EMG data were collected during 3 repetitions of each exercise performed in a random order…”
Get full text

Impact of Low PM2.5 Exposure on Asthma Admission: Age-Specific Differences and Evidence from a Low-Pollution Environment in China by Xiaolong Fan, Chen Yang, Jinsheng Chen, Yuping Chen, Gaojie Chen, Ziyi Lin, Zecong Li, Yanting Chen, Liqian Yin, Lingling Xu, Naian Xiao

“…Using a time-stratified case-crossover study design, we examined the association between PM2.5 concentration and asthma admissions from January 2019 to November 2021. …”
Get full text