Diagnostic Accuracy Of Barium Swallow For Dysphagia, Keeping Rigid Esophagoscopy As The Gold Standard by Ansa Umara Akram, Sadia Chaudhry, Sundas Masood, Amna Kausar, Seema Naveed, Areesha Manzoor

“… Objective: To determine the diagnostic accuracy of Barium Swallow in detection of patients presenting with dysphagia. Study Design: Cross-sectional validation study. Study Setting & Duration: Department of Otorhinolaryngology, Head & Neck Surgery, District Headquarter Hospital Rawalpindi from 01-09- 2022 to 01-03-2023. …”
Get full text

Karakteristik Pasien Penyakit Jantung Rematik yang Dirawat Inap di RSUP Dr. M. Djamil Padang by Marhamah Hasnul, Najirman , Yanwirasti

“…<br />This study is a descriptive observasional with cross-sectional study design and the retrospective by observing the characteristics of RHD patients in RSUP Dr. …”
Get full text

Factors associated with cancer treatment delay: a protocol for a systematic review and meta-analysis by Timothy P Hanna, Elizabeth T Jacobs, Kristin E Morrill, Rogelio Robles-Morales, Melissa Lopez-Pentecost, Raigam J Martínez Portilla, Ahlam A Saleh, Meghan B Skiba, Taylor S Riall, Jessica D Austin, Rachel Hirschey, Lena Spotleson

“…Risk of bias will be assessed independently by two authors using validated tools according to the article’s study design.Ethics and dissemination Formal ethical approval is not required because the work is being carried out on publicly accessible studies. …”
Get full text

Global Insights into Cultured Meat: Uncovering Production Processes, Potential Hazards, Regulatory Frameworks, and Key Challenges—A Scoping Review by Renata Puppin Zandonadi, Maíra Catharina Ramos, Flavia Tavares Silva Elias, Nathalia Sernizon Guimarães

“…This step involved reading full texts to confirm eligibility and extract key data, including author, year, country, study design, objectives, results, cultured meat protocols, health hazards, and hazard control measures, followed by data analysis. …”
Get full text

Satisfaction toward Quality of Care and Associated Factors among Patients Admitted to Gambella General Hospital, Gambella Region, Southwest Ethiopia by Natnael Animut, Temesgen Kabeta chala, Waju Beyene Salgedo, Muluneh Getachew Geredew, Bekalu Getachew

“…A facility-based cross-sectional study design was conducted, and a consecutive sampling technique was used to recruit 271 study subjects among patients admitted to Gambella General Hospital. …”
Get full text

Protocol of a randomised controlled phase II clinical trial investigating PREoperative endoscopic injection of BOTulinum toxin into the sphincter of Oddi to reduce postoperative pa... by Phillip Knebel, Thilo Hackert, Markus W Büchler, Thomas Bruckner, Peter Sauer, Markus K Diener, Christine Tjaden, Ulla Klaiber, Pascal Probst, Eike Martin, Steffen Luntz

“…The aim of this project (PREBOTPilot) is to generate the first randomised controlled trial data on the safety, feasibility and efficacy of preoperative endoscopic BTX injection into the sphincter of Oddi to prevent clinically relevant POPF following DP.Methods and analysis PREBOTPilot is an investigator-initiated, single-centre, randomised, controlled, open-label, phase II clinical trial with two parallel study groups and an exploratory study design. 60 patients scheduled for DP will be randomised to intervention and control group. …”
Get full text

Association of smoking with amyotrophic lateral sclerosis: A systematic review, and meta-analysis, including dose-response analysis by Kihun Kim<sup>+<sup/>, Dai Sik Ko<sup>+<sup/>, Jin-Woo Kim, Dongjun Lee, Eunjeong Son, Hyun-Woo Kim, Tae-Jin Song<sup>+<sup/>, Yun Hak Kim

“…Subgroup analyses were performed based on sex, study design, and current smoking. Restricted cubic spline analysis was utilized to assess the dose-response relationship between smoking (pack-year) and ALS. …”
Get full text

A Retrospective Case Series of a Novel Spinal Cord Stimulator Trial Technique with Less Displacement and Migration of the Trial Leads by N. Shaparin, K. Gritsenko, P. Agrawal, S. Kim, S. Wahezi, A. Gitkind, J. Hascalovici, A. Vydyanathan, J. Bernstein, A. Dizdarevic, N. Mehta, A. Kaufman

“…This study utilizes a series of 19 patients to evaluate a new technique for securing percutaneous spinal cord simulator trial leads, which may minimize dislodgement and migration complications and improve the rate of trial success. Study Design. Retrospective case series. Setting. New Jersey Medical School, Department of Anesthesiology, Pain Management Division. …”
Get full text

Quercetin Alleviates Hyperglycemic-Generated Endoplasmic Reticulum Stress-Contacted Apoptosis of Rat Nucleus Pulposus Cells by Zhen Yu, Xianfeng Wang, Yusen Hu, Xinfa Wang, Zhenghuan Zhu, Xu Xu, Yiming Wang, Ailiang Zhang

“…Aims: To investigate the influences of quercetin on apoptosis and ER stress in a high-glucose-generated primary NP cell model. Study Design: In vivo animal experimental study. Methods: To investigate the influence of quercetin in a high-glucose-generated NP cell apoptosis model, control, glucose, and glucose + quercetin groups adopted with Sprague-Dawley rats primary NP cells. …”
Get full text

Traditional Chinese Medicine Ion Introduction Therapy Reduces the Incidence of Acute Exacerbation of Idiopathic Pulmonary Fibrosis: A Prospective Cohort Study by Wang Y, Xu B, Wang J, Li S, Xie Y

“…Yan Wang,1,2 Baichuan Xu,1,2 Jiajia Wang,1,3,4 Suyun Li,1,3,4 Yang Xie1,3,4 1National Regional Traditional Chinese Medicine (Lung Disease) Diagnosis and Treatment Center, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, 450046, People’s Republic of China; 2The First Clinical College of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, 450000, People’s Republic of China; 3Henan University of Traditional Chinese Medicine Respiratory Disease Diagnosis and Treatment and New Drug Research and Development Provincial and Ministry Co-Built Collaborative Innovation Center, Zhengzhou, Henan, 450046, People’s Republic of China; 4Henan Key Laboratory of Traditional Chinese Medicine for Prevention and Treatment of Respiratory Diseases, Zhengzhou, Henan, 450046, People’s Republic of ChinaCorrespondence: Yang Xie; Suyun Li, Email xieyanghn@163.com; lisuyun2000@126.comObjective: To evaluate the effectiveness and safety of traditional Chinese medicine (TCM) ion introduction therapy in the treatment of patients with acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF).Methods: This study adopts a prospective cohort study design, with 60 AE-IPF patients as the research subjects. …”
Get full text

Heme-Iron OptiFer® in the Treatment of Iron Deficiency Anemia During Pregnancy by Ibrahim A. Abdelazim, Mohannad AbuFaza, Soud M. Al-Ajmi, Osama O. Amer, Svetlana Shikanova, Bakyt Karimova

“… OBJECTIVES: This study designed to compare the efficacy, and tolerability of heme-iron OptiFer® to ferrous fumarate in the treatment of iron deficiency anemia during pregnancy. …”
Get full text

Complications following reverse total shoulder arthroplasty for proximal humeral fractures: a systematic review by Easton J. Bents, BS, Javier Ardebol, MD, Mathew Noble, DO, Lisa Galasso, MD, Patrick J. Denard, MD, Mariano E. Menendez, MD

“…Extracted data from each article included the publishing journal, level of evidence, study design, number of patients, mean age, age range, percent female, mean follow-up, specific postoperative complications, total complications, complication rate, number of revisions, and revision rate. …”
Get full text

Prevalence and predictors of sub-optimal laboratory monitoring of selected higher risk medicines in Irish general practice: a 5-year retrospective cohort study of community-dwellin... by Fiona Boland, Emma Wallace, Frank Moriarty, Tom Fahey, Caroline McCarthy, Ann Sinéad Doherty, Mark Feighery

“…Objectives To describe the prevalence of sub-optimal monitoring for selected higher-risk medicines in older community-dwelling adults and to evaluate patient characteristics and outcomes associated with sub-optimal monitoring.Study design Retrospective observational study (2011–2015) using historical general practice-based cohort data and linked dispensing data from a national pharmacy claims database.Setting Irish primary care.Participants 625 community-dwelling adults aged ≥70 years and prescribed at least one higher-risk medicine during the 5-year study period.Primary and secondary outcome measures The primary outcome was the prevalence of sub-optimal laboratory monitoring using a composite measure of published medication monitoring indicators, with a focus on commonly prescribed higher-risk medicines such as diuretics and anticoagulants. …”
Get full text

Clinical and Radiological Manifestations of Pulmonary Tuberculosis, Jazan Region, Saudi Arabia by Abuobaida Yassin, Heba M. Shalaby

“…Settings and Design: This cross-sectional study design was conducted at Jazan Chest Hospital in the Jazan region of SA over 10 months. …”
Get full text

Factors associated with knowledge and attitude towards adult cardiopulmonary resuscitation among healthcare professionals at the University of Gondar Comprehensive Specialized Hosp... by Abraham Tarekegn Mersha, Amare Haile Kiros Gebre Egzi, Hailu Yimer Tawuye, Nigussie Simeneh Endalew

“…Objective This study was conducted to assess the factors associated with knowledge and attitude towards adult cardiopulmonary resuscitation (CPR) among health professionals at the University of Gondar Hospital, Northwest Ethiopia.Study design An institutional-based cross-sectional study was conducted from 15 February to 15 March 2018. …”
Get full text

Assessment of Treatment Outcomes and Associated Factors Among Pediatric Patients With Burkitt Lymphoma at Kenyatta National Hospital by Divya Kumari Toor, Amsalu Degu, Peter N. Karimi

“…Because of the retrospective nature of the study design, the data accuracy relied on the proper documentation of medical records in the study setting. …”
Get full text

Clinical usefulness of patient-reported-outcome-measurement information system in Pediatric Crohn’s Disease: a cross-sectional study by Sara Azevedo, Maria Miguel Oliveira, Paulo Nogueira, Ana Isabel Lopes

“…Abstract Objectives This study evaluated the clinical utility of the Patient-Reported Outcomes Measurement Information System (PROMIS®) by comparing it with objective clinical data and validated health-related quality of life (HRQOL) measures in pediatric Crohn’s disease (CD) patients. Study design Cross-sectional study. Pediatric CD patients (aged 8–17 years) were enrolled prospectively over eight months from an outpatient pediatric gastroenterology center. …”
Get full text

Maximal and Explosive Muscle Strength During Hip Adduction Squeeze and Hip Abduction Press Test Using A Handheld Dynamometer: An Intra- and Inter-tester Reliability Study by Lasse Ishøi, Kristian Thorborg, Laura Krohn, Lars Louis Andersen, Asger Møller Nielsen, MIkkel Bek Clausen

“… # Hypothesis/purpose The aim of the present study was to assess intra- and inter-tester reliability of maximal, and explosive strength during the long lever hip adduction squeeze test and the long lever hip abduction press test in healthy adults using a hand-held dynamometer. # Study design Intra- and interrater reliability study…”
Get full text

Utilizing Hip Abduction Strength to Body-Weight Ratios in Return to Sport Decision-Making After ACL Reconstruction by Steven Higbie, Jacquelyn Kleihege, Brian Duncan, Walter R. Lowe, Lane Bailey

“… # Hypothesis/Purpose The purpose of this study was to compare self-reported function, objective functional test performance, and re-injury rates in patients with high (≥33%) versus low (<33% ) isometric hip abduction strength to body weight (BW) ratios when returning to activity following ACLR. # Study Design Cohort study # Methods Data were gathered from a single-surgeon database and included baseline demographics. …”
Get full text

Co-designing action-oriented mental health conversations between care providers and ageing Canadians in the community: a participatory mixed-methods study protocol by Carrie McAiney, Paul Holyoke, Heather McNeil, Justine L Giosa, Elizabeth Kalles, Nelly D Oelke, Katie Aubrecht, Olinda Habib Perez

“…This study aims to co-design and test an evidence-based approach to mental health conversations at the point-of-care in home and community settings with older adults, family and friend caregivers and health and social care providers that could facilitate help-seeking activities and care access.Methods and analysis A participatory mixed-methods study design will be applied, guided by a Working Group of experts-by-experience (n=30). …”
Get full text