Comparative analyses of the hemostatic efficacy and surgical device performance of powdered oxidized regenerated cellulose and starch-based powder formulations by Marianne Stark, Allen Y. Wang, Brittny Corrigan, Henok G. Woldu, Samar Azizighannad, Gustavo Cipolla, Richard Kocharian, Hector De Leon

“…Methods: Efficacy was evaluated in a porcine model of bleeding using 2 study designs where the powder was delivered with (experiment 1) and without (experiment 2) device applicators. …”
Get full text

Specialized pediatric palliative care in Italy: where are we going? The Palliped 2022–2023 study by Franca Benini, Anna Mercante, Sara Di Nunzio, Simonetta Papa, the PalliPed 2022-2023 Working Group

“…Abstract Background The PalliPed project is a nationwide, observational, cross-sectional study designed with the aim of providing a constantly updated national database for the census and monitoring of specialized pediatric palliative care (PPC) activities in Italy. …”
Get full text

Exercise interventions to improve bone mineral density in athletes participating in low-impact sports: a scoping review by Anders Gulbrandsen Florvåg, Øyvind Angelshaug Berg, Ola Drange Røksund, Gøril Tvedten Jorem, Bård Erik Bogen

“…However, there is limited evidence due to few identified studies, with varying study designs and inconsistent exercise reporting, highlighting the need of further research to better understand how different training approaches can improve bone health in these athletes.…”
Get full text

An exergy-based analysis for the synthesis of aromatics from biomass by Mohammed Usman, Joseph Akintola, Gabriel Umoh, Joseph Akpan, Ekpotu Wilson, Queen Moses, Philemon Udom, Edose Osagie

“…In response to these challenges and considering the industry's capital-intensive nature, ongoing optimization through redesigning existing production plants has become a key strategy. This study designs and analyses a typical process plant with two routes for synthesizing aromatics from methanol and pentane. …”
Get full text

Design and Experimental Evaluation of a Smart Intra-Row Weed Control System for Open-Field Cabbage by Shenyu Zheng, Xueguan Zhao, Hao Fu, Haoran Tan, Changyuan Zhai, Liping Chen

“…Addressing the challenges of complex structure, limited modularization capability, and insufficient responsiveness in traditional hydraulically driven inter-plant mechanical weeding equipment, this study designed and developed an electric swing-type opening and closing intra-row weeding control system. …”
Get full text

Association of functional health literacy and cognitive ability with self-reported diabetes in the English Longitudinal Study of Ageing: a prospective cohort study by Ian J Deary, Chloe Fawns-Ritchie, Jackie Price

“…Objectives We investigated whether functional health literacy and cognitive ability were associated with self-reported diabetes.Design Prospective cohort study.Setting Data were from waves 2 (2004–2005) to 7 (2014–2015) of the English Longitudinal Study of Ageing (ELSA), a cohort study designed to be representative of adults aged 50 years and older living in England.Participants 8669 ELSA participants (mean age=66.7, SD=9.7) who completed a brief functional health literacy test assessing health-related reading comprehension, and 4 cognitive tests assessing declarative memory, processing speed and executive function at wave 2.Primary outcome measure Self-reported doctor diagnosis of diabetes.Results Logistic regression was used to examine cross-sectional (wave 2) associations of functional health literacy and cognitive ability with diabetes status. …”
Get full text

Association of leukocyte elastase in semen and seminal plasma with sperm parameters and pregnancy outcomes in male fertility by Mausumi Das, Maha Gumssani, Julia Mullaney, Ralf Henkel, Suks Minhas, Marie Claire Aquilina, Channa N Jayasena

“…A narrative synthesis was used because of differing study designs. Quality assessment, using the National Heart, Lung, and Blood Institute tool, rated 21 studies medium quality, 6 high and 1 low. …”
Get full text

New Insights Into Hepatic Impairment (HI) Trials by Sebastian Haertter, Maximilian Lobmeyer, Brian C. Ferslew, Pallabi Mitra, Thomas Arnhold

“…This review aimed at looking into the data from dedicated HI studies, cluster these data into various categories and connect the effect by HI with reported pharmacokinetics (PK) properties in order to identify patterns that may allow waiver, extrapolations, or adapted HI study designs. Based on a ratio ≥ 2 or ≤ 0.5 in AUC or Cmax between hepatically impaired participants/healthy controls these were considered “positive” or “negative”. …”
Get full text

Using Deep Learning to Identify High-Risk Patients with Heart Failure with Reduced Ejection Fraction by Zhibo Wang, Xin Chen, Xi Tan, Lingfeng Yang, Kartik Kannapur, Justin L. Vincent, Garin N. Kessler, Boshu Ru, Mei Yang

“…For DL models to predict HF hospitalizations and worsening HF events, we utilized two study designs: with and without a buffer window. For comparison, we also tested multiple traditional machine learning models including logistic regression, random forest, and eXtreme Gradient Boosting (XGBoost). …”
Get full text

Investigating the psychology of eating after exercise — a scoping review by Alice Porter, Russell Jago, Luke A Robles, Elin Cawley, Peter J. Rogers, Danielle Ferriday, Jeffrey M. Brunstrom

“…Search terms relating to exercise, eating behaviour, and compensatory eating were used. All study designs were included. Research in children, athletes, or animals was excluded. …”
Get full text

Soap and water cleaning versus bleach-based cleaners for eliminating SARS-CoV-2 infection by Ekong E. Udoh, Ubong A. Udoh, Abiodun Egwuenu, Ekpereonne B. Esu, Aruk Eteng, Faithman E. Ovat, Uduak Okomo, Olabisi Oduwole, Joseph Okebe, Martin Meremikwu

“…We prioritised systematic reviews and randomised studies and only included other study designs, such as laboratory studies, which had interventions of relevant interest. …”
Get full text

Association of Cardiovascular Risk Factors With Major and Minor Electrocardiographic Abnormalities: A Report From the Cross‐Sectional Phase of Tehran Cohort Study by Pooria Ahmadi, Sajjad Ahmadi‐Renani, Parmida Sadat Pezeshki, Sepehr Nayebirad, Arash Jalali, Akbar Shafiee, Aryan Ayati, Arian Afzalian, Farshid Alaeddini, Soheil Saadat, Farzad Masoudkabir, Ali Vasheghani‐Farahani, Saeed Sadeghian, Mohamamdali Boroumand, Abbasali Karimi, Boshra Pourbashash, Kaveh Hosseini, Frits R. Rosendaal

“…Methods We used the Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal study designed to identify cardiovascular disease risk factors in the adult population of Tehran. …”
Get full text

Impact of empiric antibiotics on risk of Clostridioides difficile—a causal inference observational analysis by Matthew A. Pappas, Shoshana J. Herzig, Andrew D. Auerbach, Abhishek Deshpande, Eunice Blanchard, Michael B. Rothberg

“…Causal inference observational study designs can be used to estimate patient-level harms of interventions such as empiric antimicrobials. …”
Get full text

Effects of traditional Chinese exercises on brain-derived neurotrophic factor in middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials by Jianyu Gan, Jiya He, Kaixiang Zhou, Zhangyuting Shang, Gengxin Dong, Dapeng Bao, Junhong Zhou

“…Recent studies suggested that Traditional Chinese exercises (TCEs) may be a promising strategy to improve the BDNF levels of these populations, while the effectiveness has yet to be definitively confirmed due to the variances in the study designs and observations. Therefore, this systematic review and meta-analysis aimed to examine the effects of TCEs intervention on BDNF in middle-aged and older adults. …”
Get full text

Development of the Dutch translational knowledge agenda for inherited metabolic diseases by I. J. Hieltjes, J. H. van derLee, M. C. Groenendijk, G. vanHaaften, P. M. vanHasselt, R. J. Lunsing, G. J. J. vanProoijen, E. M. deRuiter, F. J. vanSpronsen, N. M. Verhoeven‐Duif, A. deVreugd, M. Wagenmakers, H. Zweers, H. Dekker, H. R. Waterham, C. D. vanKarnebeek, R. J. A. Wanders, R. A. Wevers

“…The resulting top 10 research questions cover multiple themes, i.e. prediction of disease progression, development of novel tools, mechanistic insights, improved diagnostics, therapeutic integration of multi‐omics techniques, assessment of impact on daily life, expanding treatment avenues, optimal study designs, effect of lifestyle interventions, and data utilization using FAIR principles. …”
Get full text

The clinical impact of conventional therapies for adults and adolescents suffering from eosinophilic esophagitis, a type 2 inflammatory chronic disease, and their economic conseque... by Giorgio Walter Canonica, MD, Gherardo Mazziotti, MD, PhD, Alessandro Repici, MD, Massimiliano Povero, PhD, Luca Castello, MSc, Lorenzo Pradelli, MD, Miryana Dobreva, MSc, Francesca Fanelli, MSc, Jean Pierre Saab, MD, Edoardo Vincenzo Savarino, MD, PhD

“…Meta-analyses were performed to evaluate treatment efficacy and safety across various patient populations and study designs. Results: TCSs showed superior efficacy over PPIs in achieving histologic, endoscopic, and partial clinical responses. …”
Get full text

Oral health risks in adults who use electronic nicotine delivery systems and oral nicotine pouches: a critical review of the literature and qualitative synthesis of the available e... by Gerhard Scherer, Nikola Pluym, Max Scherer

“…These results have to be interpreted with caution due to a number of limitations and uncertainties in the underlying studies, particularly the potential biases and confounding factors inherent in cross-sectional study designs.…”
Get full text

Barriers and enablers to young people accessing sexual and reproductive health services in Pacific Island Countries and Territories: A scoping review. by Maggie Ikinue Baigry, Robin Ray, Daniel Lindsay, Angela Kelly-Hanku, Michelle Redman-MacLaren

“…We assessed the quality of each study according to the study designs, methods of data collection, data analysis and ethical considerations. …”
Get full text

A Scoping Review of Factors Associated with Delayed Extubation in Post Cardiac Surgery Patients by Kumalasari RI, Kosasih CE, Priambodo AP

“…The articles analyzed met the inclusion criteria, such as full-text articles in English, published from 2014– 2024, with case-control, cross-sectional, longitudinal, and cohort study designs and had good quality as assessed using the Joanna Briggs Institute critical appraisal checklist. …”
Get full text

The effectiveness of dyadic interventions for health outcomes of prostate cancer patients and informal caregivers: a systematic review and meta-analysis by Yuan Xiao, Jiao Sun, Min Liu, Haifeng Wang, Jingjing Guan

“…However, given features such as research quality and sample size, further randomized controlled trials with excellent study designs are needed in the future to evaluate and validate the efficacy of dyadic care treatments for patients with prostate cancer. …”
Get full text