A qualitative research on the willingness and influencing factors of participating in early screening among ethnic minority patients with breast cancer in rural areas (农村地区少数民族乳腺癌患... by ZHANG Xuan (张旋), PEI Qiuping (裴秋萍), YOU Jiaojiao (游娇娇), HUANG Shuai (黄帅)

“…Methods Between January 2022 and June 2022, a phenomenological research method was conducted and 12 patients with breast cancer were selected for a semi-structured retrospective interview, and the Colaizzi phenomenological data analysis method was used for analysis. …”
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Ethnobotanical survey on anti-tuberculosis plants in Mbujimayi, Democratic Republic of the Congo by Malangu Lambert Muamba, Kitambala Marsi Mbayo, Numbi Evodie Wa Ilunga, Ilunga Eddy Mbuyu, Kabeya Justin Kanda, Otete François Dikala, Ebalantshim Daniel Munakongo, Mwinensenge James Maloba, Nonga Welcome Muyumba, Kalonji Serge Mbuyi, Muya Richard Kalunga, Tsheko Manya, Kihuya Eddy Ngoy, B. J. Kanangila, Mutombo Emery Kalonda, Kankenza Léonard Kalanda, Simbi Jean-Baptiste Lumbu, Clement L. LIYONGO

“…Methods An ethnobotanical survey was conducted through interviews using a structured questionnaire with 46 resource persons, including household members, herbalists, and traditional practitioners. …”
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Behavior of SD-OCT Detectable Hyperreflective Foci in Diabetic Macular Edema Patients after Therapy with Anti-VEGF Agents and Dexamethasone Implants by Anne Rübsam, Laura Wernecke, Saskia Rau, Dominika Pohlmann, Bert Müller, Oliver Zeitz, Antonia M. Joussen

“…Spectral-domain optical coherence tomography (SD-OCT) allows detection and monitoring of the edema and a detailed analysis of the retinal structure. Hyperreflective foci (HF) are small, circumscribed lesions on OCT, and their origin is yet to be determined. …”
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Pharmacological management of gambling disorder: A systematic review and network meta-analysis by Konstantinos Ioannidis, Cinzia Del Giovane, Charidimos Tzagarakis, Jeremy E. Solly, Samuel J. Westwood, Valeria Parlatini, Henrietta Bowden-Jones, Jon E. Grant, Samuele Cortese, Samuel R. Chamberlain

“…Methods: Based on our pre-registered protocol [CRD42022329520], a structured search was conducted across broad range of databases, for double-blind randomized controlled trials (RCTs) of medications for gambling disorder. …”
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High concentrations of polyethylene microplastics restrain the growth of Cinnamomum camphora seedling by reducing soil water holding capacity by Run Yang, Jinping Wang, Huanying Fang, Jinwen Xia, Guomin Huang, Rongzhen Huang, Hong Zhang, Liqin Zhu, Lichao Zhang, Jihong Yuan

“…Furthermore, high concentrations of PE-MPs (1 % and 2 %) greatly decreased soil alkali-hydrolysable nitrogen content and decreased bacterial diversity. The structural equation model clearly indicated that the inhibitory effect of soil PE-MPs with high concentrations on seedling growth was mainly derived from the decrement of soil water holding capacity. …”
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Effects of cold-pressed wheat germ oil and Bacillus subtilis on growth performance, digestibility, immune status, intestinal microbial enumeration, and gene expression of broilers... by Abdel-Moneim Eid Abdel-Moneim, Safaa A.M. Ali, M.G. Sallam, Ahmed M. Elbaz, Noura M. Mesalam, Zangabel S. Mohamed, AbdelRahman Y Abdelhady, Bing Yang, Mohamed Farouk Elsadek

“…Notably, CWB supplements modified the structure of the cecal microbial community by increasing Lactobacillus counts and decreasing E. coli and C. perfringens counts. …”
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Why do patients with isolated PCL rupture experience no subjective knee joint instability during walking? An in vivo biomechanical study by Mingfeng Lu, Mingfeng Lu, Wei Chen, Jinpeng Lin, Jinpeng Lin, Wenhan Huang, Junqing Gao, Junqing Gao, Lilian Zhao, Shilin Li, Lilei He, Yu Zhang

“…ObjectiveThe aim of this study is to assess the kinematic changes in the knee joint during walking in patients with isolated PCL-deficiency (PCLD) to determine the presence of walking-related joint instability (mechanical instability—abnormal displacement form structural damage). Additionally, the study seeks to provide biomechanical insights into the observed differences between subjective and objective assessments.Methods35 healthy volunteers and 27 patients with isolated PCLD (both involved and uninvolved sides) were included in the study. …”
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Application of Biochar-Immobilized <i>Bacillus megaterium</i> for Enhancing Phosphorus Uptake and Growth in Rice by Keru Yu, Zhenyu Wang, Wenyan Yang, Shuai Li, Dongtao Wu, Hongtao Zheng, Zhengqian Ye, Shaona Yang, Dan Liu

“…Biochar serves as a carrier that enhances microbial survival, and its porous structure and surface characteristics ensure the adsorption of <i>Bacillus megaterium</i>. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…Framework and thematic analysis were used to analyse the findings.Setting England and Wales, UK.Participants Adults discharged from National Health Service (NHS) hospitals at least 3 months previously after COVID-19, with ongoing physical and/or mental health sequelae.Results Twenty intervention participants, 20 control participants and five practitioners were interviewed.The themes from the group support sessions were: (1) you are not alone; (2) sharing experiences and addressing worries; (3) gaining new perspectives; (4) hope for progression; (5) peer support and bonding; (6) integration of facilitation skills; (7) modified activity pacing and goal setting, and (8) giving participants structure. The themes from group exercise were: (1) monitoring and modification of the online exercise; (2) catering for differing abilities; (3) feeling safe and confident to exercise; (4) progression of fitness; (5) optimal timing in the recovery trajectory; (6) group effect; (7) initial apprehension about exercise group; (8) gauging exercise capabilities; (9) translating exercises into life; and (10) on-demand supplementary videos. …”
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Antimicrobial Activities of Polysaccharide-Rich Extracts from the Irish Seaweed <i>Alaria esculenta</i>, Generated Using Green and Conventional Extraction Technologies, Against Foo... by Ailbhe McGurrin, Rahel Suchintita Das, Arturo B. Soro, Julie Maguire, Noelia Flórez Fernández, Herminia Dominguez, Maria Dolores Torres, Brijesh K. Tiwari, Marco Garcia-Vaquero

“…Microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), ultrasound–microwave-assisted extraction (UMAE), and conventional extraction technologies (maceration) were applied to generate extracts from <i>A. esculenta</i>, followed by their preliminary chemical composition (total phenolic content, total protein content, total soluble sugars) and antimicrobial activity (with minimum inhibitory concentration determined by broth microdilution methods), examining also the molecular weight distribution (via high performance size exclusion chromatography) and oligosaccharide fraction composition (via high-performance liquid chromatography) of the polysaccharides, as they were the predominant compounds in these extracts, aiming to elucidate structure–function relationships. The chemical composition of the extracts demonstrated that they were high in total soluble sugars, with the highest total sugars being seen from the extract prepared with UAE, having 32.68 mg glucose equivalents/100 mg dried extract. …”
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An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India... by Vaman Khadilkar, Tarun Reddy Katapally, Jasmin Bhawra, Neha Kajale, Rubina Mandlik, Vivek Patwardhan, Demi Miriam, Dipali Ladkat, Chidvilas More, Ketan Gondhalekar, Anuradha Vaman Khadilkar

“…The long-term data analysis plan includes longitudinal modelling, time-series analyses, structural equation modelling, multilevel modelling and sex-based analyses to investigate growth trajectories and intergenerational patterns of health risks. …”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This would suggest that education and self-management skills should be seen as an integral component of asthma management and should be incorporated in structured patient care to achieve optimal asthma control.…”
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A bioinformatic search for correspondence between differentially expressed genes of domestic versus wild animals and orthologous human genes altering reproductive potential by M. P. Ponomarenko, I. V. Chadaeva, P. M. Ponomarenko, A. G. Bogomolov, D. Yu. Oshchepkov, E. B. Sharypova, V. V. Suslov, A. V. Osadchuk, L. V. Osadchuk, Yu. G. Matushkin

“…Belyaev’s discovery of destabilizing selection during the domestication of animals and that this selection affects only gene expression regulation (not gene structure) and influences systems of neuroendocrine control of ontogenesis in a stressful environment. …”
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Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

“…Furthermore, HG9-91-01 was found to protect the retinal structure and reduce the loss of retinal layers in an acute glaucoma model. …”
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Evaluation of the effectiveness of GASMAN anesthesia simulation software combined with case-based learning versus traditional lecture-based learning in inhalation anesthesia educat... by Chao Chen, Chao Chen, Shengfeng Yang, Xinglong Xiong, Xinglong Xiong, Yewei Shi, Yewei Shi, Zhenyan Zhu, Zhenyan Zhu, Jing Shi, Jing Shi

“…The cases used in the IGC group were structured around realistic clinical scenarios, simulating real-world challenges in inhalation anesthesia. …”
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Diagnosis of hepatocellular carcinoma using liquid biopsy-based biomarkers: a systematic review and network meta-analysis by Yutong Jiang, Yutong Jiang, Shangwen Qi, Shangwen Qi, Rongrong Zhang, Rongrong Zhang, Ruixia Zhao, Yu Fu, Yuxuan Fang, Yuxuan Fang, Mingyi Shao

“…Subsequent analysis of circRNA and mRNA highlighted hsa_circ_000224, hsa_circ_0003998, KIAA0101 mRNA and GPC-3mRNA as the optimal diagnostic biomarkers for distinguishing HCC from healthy populations and liver disease patients, respectively. Well-structured prospective studies are crucial to comprehensively validate these findings.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/,identifier CRD42024521299.…”
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Assessing the efficacy of iso-mukaadial acetate and betulinic acid against selected Plasmodium falciparum glycolytic pathway proteins: in silico and in vitro studies by Lindiwe Khumbuzile Zuma, Ofentse Jacob Pooe, Nonduduzo Hlengiwe Mabaso, John Alake, Vincent A. Obakachi, Sinethemba Yakobi, Nothando Gasa, Rajshekhar Karpoormath, Mthokozisi Simelane

“…FTIR experiments confirmed interactions between the compounds and the secondary structure of the proteins. Direct protein–ligand interaction studies analysis using microscale thermophoresis (MST) showed a KD value of 0.1036 ± 0.6001 µM for the PfLDH-BA complex and 0.7473 ± 0.3554 µM KD value for PfLDH-IMA. …”
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Addressing evidence needs during health crises in the province of Quebec (Canada): a proposed action plan for rapid evidence synthesis by Quan Nha Hong, Esther McSween-Cadieux, Maxime Guillette, Luiza Maria Manceau, Jingjing Li, Vera Granikov, Marie-Pascale Pomey, Marie-Pierre Gagnon, Saliha Ziam, Christian Dagenais, Pierre Dagenais, Alain Lesage, Thomas G. Poder, Martin Drapeau, Valéry Ridde, Julie Lane

“…Results A total of 14 specific actions structured into four main axes were identified over the three phases. …”
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Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation by Yudi Li, Yudi Li, Alona Armstrong, Alona Armstrong, Christopher Simmons, Noah Z. Krasner, Noah Z. Krasner, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez, Rebecca R. Hernandez

“…Marked differences in vegetation across micro-patches indicated that GPVs drive changes in plant community composition, structure, and productivity. Compared to open spaces, vegetation near and within the PV array footprint displayed greater species richness (+8.4%), taller maximum height (+21%), reduced coverage of sun-loving plants (−71%), and less dead biomass accumulation (−26%), from shade-driven effects. …”
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A qualitative research on health education needs of pregnant women with gestational diabetes mellitus (妊娠期糖尿病孕产妇健康教育需求的质性研究) by TAN Minjing (覃敏静), YANG Miaomiao (杨苗苗), WANG Kaihua (王凯华), LUO Chunmiao (罗春苗), ZHOU Jinchang (周金嫦)

“…The phenomenological research method in the qualitative research was used to conduct semi-structured interviews. The Colaizzi's 7-step analysis method was used to analyze the data. …”
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